Table of Content

Open Access Original Research

Breaking Barriers: A Reliable Method for RNA Extraction in Zebrafish Neurodegenerative Research

Received: 02 June 2024;  Published: 30 September 2024;  doi: 10.21926/obm.neurobiol.2403246

Abstract

Zebrafish (Danio rerio) is a vertebrate with unique characteristics, making it an excellent biomedical research animal model. One research area involves investigating changes in gene expression during neurodegenerative processes, aging-related changes, and behavioral studies in zebrafish. To achieve this, high-quality and quantity RNA must be extracted from zebrafish. This study aims to develop an optimized RNA extraction method from zebrafish larvae brains. After rearing and maintaining the zebrafish in suitable c [...]

1799 8074

Open Access Opinion

"Let's Live Life - Let's Give Life": Donor Program Improvement as the Key to Transplantation Success in 21st Century - A Croatian Experience

Received: 30 August 2022;  Published: 15 November 2022;  doi: 10.21926/obm.transplant.2204169

Abstract

Transplantation is a widely accepted and successful life-saving treatment for hundreds of thousands of patients. However, transplant medicine still faces a number of obstacles. One of the most significant is the large disparity between the number of donors and recipients and the growing need for re-transplantation. In the last two decades, the improvement and organization of the national transplantation program in Croatia have resulted in a steadily increasing donor rate and therefore the transplantation numbers. A [...]

1001 8073

Open Access Original Research

Brain Imaging Studies Using Deep Neural Networks in the Detection of Alzheimer's Disease

Received: 29 June 2022;  Published: 03 January 2023;  doi: 10.21926/obm.geriatr.2301220

Abstract

The increasing incidence of adult-onset dementia disorders and primarily Alzheimer’s disease (AD) among the aging population around the world is increasing the social and economic burden on society and healthcare systems. This paper presents three neural networking algorithms: MobileNet, Artificial Neural Networks (ANN), and DenseNet for AD classification based on MRI imaging data. The results of each model were compared in terms of performance metrics such as accuracy, true positive rate, and receiver operating cu [...]

1239 8061

Open Access Research Article

1-Decylbenzimidazole Copper(II) Complexes: Combined Experimental and DFT PCM and TD-DFT Computational Studies

Received: 29 June 2020;  Published: 27 August 2020;  doi: 10.21926/acr.2003007

Abstract

1-Decylbenzimidazole (dbim) copper(II) complexes formed during solvent extraction were thoroughly studied, and their structures were predicted. Density functional theory (DFT) calculations of their structures and Time-dependent DFT (TD-DFT) calculations of their spectra indicated that 1-decylbenzimidazole forms both mono- and binuclear complexes with copper(II), with coordination numbers of 4 or 5. At the molar ratio of [Cu(II)]aq/[dbim]org ≥ 1 and at [Cl-]aq ≥ 0.9 mol dm-3 in the extraction media, a binuclear 1:1 [...]

1533 8053

Open Access Case Report

Anticoagulation Rationale in an Elderly Patient with Stroke, Cerebral Amyloid Angiopathy, and Antiphospholipid Syndrome: A Case Report

Received: 29 September 2020;  Published: 24 December 2020;  doi: 10.21926/obm.geriatr.2004145

Abstract

We present a case of a 74-year-old woman with deep intracerebral hemorrhage (ICH), probable cerebral amyloid angiopathy (CAA), and probable antiphospholipid syndrome (APS). Due to the high hemorrhagic risk, it was decided not to use anticoagulants. In a period of three months, she had two separate cerebral ischemic events and died of stroke-related complications. The use of oral anticoagulation (OAC) in this patient is neither supported nor contra-indicated by current literature, even though past medical history su [...]

1814 8041

Open Access Editorial

The Human Touch in Acupuncture: A Future with Artificial Intelligence?

Received: 05 January 2025;  Published: 07 January 2025;  doi: 10.21926/obm.icm.2501003

Abstract

Acupuncture, an ancient practice in traditional Chinese medicine, is founded on understanding of human physiology and the dynamics of energy flow (Qi). The emergence of artificial intelligence (AI) in modern medicine presents opportunities to integrate advanced technologies into acupuncture, enhancing diagnostic precision and empirical validation. AI tools can analyze complex datasets, model energy flow dynamics, and provide evidence-based insights, potentially bridging traditional methodologies with scientific par [...]

1047 8040

Open Access Review

Emerging Advances in 3-D & 4-D Printing of Polymeric Nanoarchitectures & Multifacet Applications

Received: 05 September 2024;  Published: 02 February 2025;  doi: 10.21926/rpm.2501005

Abstract

3-Dimension printing (3-DPT) or additive manufacturing (AM) technology has been utilized for a while in the construction of customized 3-D objects utilizing computer software such as computer-aided design (CAD). However, the emergence of an innovative and new four-dimensional printing (4-DPT) has enabled the synergy of AM technology with programmable materials in transforming digital processes virtually into physical entities, thereby providing innovation and advanced functionalities. 4-DPT is a procedure facilitat [...]

2209 8033

Open Access Research Article

Evaluation of Pyrolysis Products of Industrial Wastes as Potential Feedstocks for Bioenergy and Biofuels

Received: 02 November 2022;  Published: 11 January 2023;  doi: 10.21926/aeer.2301005

Abstract

This work aimed at evaluating all products from the low-temperature pyrolysis (350°C) of some industrial wastes, cotton stems and seeds (CSS), grape husks and curls (GRH), undigested sewage sludge (USS) and their blends in a fixed bed system and suggesting their possible applications. Solid and liquid products, biochars, and bio-oils were analyzed using various techniques by physicochemical, mineralogical, and chemical analyses. Gases were qualitatively and quantitatively analyzed using a thermogravimetric-mass [...]

1659 8024

Open Access Original Research

Is Wheelchair Basketball a Symmetric or Asymmetric Sport?

Received: 16 January 2024;  Published: 25 June 2024;  doi: 10.21926/obm.neurobiol.2402227

Abstract

Wheelchair basketball (WB) is a health and inclusion opportunity for people with disabilities. In the scientific literature, no evidence defines WB as a symmetrical or asymmetrical sport; however, it would be helpful to deepen this aspect because it could improve the quality of training programs and consequently speed up WB performance. In WB, the biomechanical role of the shoulders is crucial. Therefore, the symmetry index and the activation of the bilateral supraspinatus and biceps brachii muscles were investigat [...]

1228 8021

Open Access Original Research

Nature and City Sounds Influence Physiological and Psychological Markers in College Students

Received: 02 March 2023;  Published: 28 September 2023;  doi: 10.21926/obm.icm.2303039

Abstract

Worldwide, human population growth has led to a higher demand for urbanization. While this development is in accordance with our gregarious lifestyles, our availability and contact with nature has consequentially been minimized. The goal of this study was to evaluate whether sounds from nature versus urban environments affect vital signs (i.e., heart rate and respiration rate) and mood states of female college students. Emotional states were assessed using the Positive and Negative Affect Schedule (PANAS) questionn [...]

1392 8019

TOP