Table of Content

Open Access Technical Note

Towards Femtoscan-Assisted Analysis of Liquid Crystal Self-Organization on Different Polymer and Glass Surfaces for Lab-on-a-Chip and Lab-on-a-Dish Applications, Including Optofluidic and Flexoelectric Ones

Received: 27 December 2022;  Published: 29 May 2023;  doi: 10.21926/rpm.2302022

Abstract

In this paper, starting with an introductory review of the applications of liquid crystals and polymer-dispersed liquid crystal systems in (bio)sensors and microfluidics, the possibilities of visualizing self-organization products of liquid crystalline media or field-induced instabilities of liquid crystalline systems are considered. In particular illustrated cases, it is proposed to use FemtoScan software-containing metrological complexes to visualize instabilities in liquid crystalline systems and products of sel [...]

1830 8163

Open Access Review

Mycobacterium Tubercular Mediated Inflammation and Lung Carcinogenesis: Connecting Links

Received: 03 September 2022;  Published: 21 June 2023;  doi: 10.21926/obm.genet.2302183

Abstract

Lung cancer is a leading cause of death among all the cancer worldwide and it has the highest occurrence and mortality rates. Mycobacterium tuberculosis (MTB) induced tuberculosis has been known as one of the risk factors for lung carcinogenesis. The exact mechanism of MTB is understood to date. Several research and epidemiological studies about the link between tuberculosis and lung cancer exist. It has been proposed that tuberculosis causes chronic inflammation, which increases the risk of lung cancer by creating [...]

1184 8160

Open Access Review

Emerging Roles of Signal Transduction Pathways in Neurodegenerative Diseases. Hunting New Possible Therapeutic Molecular Targets

Received: 27 January 2023;  Published: 05 May 2023;  doi: 10.21926/obm.geriatr.2302234

Abstract

Illnesses following the degeneration of the nervous system can occur due to aging or genetic mutations and represent a clinical concern. In neurodegenerative diseases, loss of neuronal structure and functions mainly causes cognitive impairment, representing an increasing social burden. In neurodegenerative diseases, the progressive loss of vulnerable populations of neurons in specific regions of the central nervous system was traced to different pathological events, such as misfolded proteins’ accumulation, abnorma [...]

1222 8153

Open Access Original Research

Comparing Two Strategies for Locating Hydrogen Refueling Stations under High Demand Uncertainty

Received: 21 February 2023;  Published: 15 May 2023;  doi: 10.21926/aeer.2302031

Abstract

This research aims to model and compare two strategies for locating new hydrogen refueling stations (HRS) in a context of high uncertainty on H2 demand and on the spatial distribution of demand points. The first strategy S1 represented by an agent-based model integrating a particle swarm optimization metaheuristic consists of finding the best HRS locations by adapting to the real evolution of the demand. A second strategy S2 consists in solving a classical capacitated p-median problem based on H2 consumption foreca [...]

1194 8150

Open Access Review

Perspectives to Modify and Counter Aging in the Frame of Subtelomere–Telomere Theory of Aging

Received: 22 July 2022;  Published: 14 October 2022;  doi: 10.21926/obm.geriatr.2204208

Abstract

The interpretation of aging as an adaptive and programmed phenomenon implies the existence of specific genetically determined and regulated aging-causing mechanisms. This interpretation is in contrast to the explanation of aging as the gradual accumulation of the effects of harmful factors that are only partially countered by natural selection. The subtelomere–telomere theory of aging offers what is required by the interpretation of aging as a programmed phenomenon. The experimentally documented mechanisms that are [...]

1274 8149

Open Access Original Research

Dancing Exercise Enhances Metabolic Functions via Hypercortisolism-Mediated Inhibition of Inflammatory Cytokines in Healthy Adult Volunteers

Received: 04 December 2023;  Published: 27 February 2024;  doi: 10.21926/obm.icm.2401015

Abstract

Regular physical activity has been proven to improve metabolism, slow aging, and decrease the likelihood of various health conditions such as obesity, type 2 diabetes, and cardiovascular disorders. Hence, dancing was evaluated for its effects on cardiovascular, liver enzymes, and biochemical markers among healthy adults. Forty (40) healthy adults (20-40 years old) were chosen for the study, with an average age calculated. Those with certain health conditions or habits were not allowed to participate. Twenty (20) me [...]

1177 8140

Open Access Review

Secondary Findings of Newborn Screening

Received: 16 April 2023;  Published: 31 August 2023;  doi: 10.21926/obm.genet.2303191

Abstract

The aim of newborn screening (NBS) program is to detect and manage treatable conditions in the early stages prior to the occurrence of long-term and irreversible sequalae. Phenylketonuria was the first screened disorder, but panels rapidly expanded after the introduction of tandem mass spectrometry technology into the program. Significant differences in the diseases screened by NBS were noted between programs in United States. Therefore, the recommended uniform screening panel was developed in 2006 to include a lis [...]

1505 8129

Open Access Short Review

Arterial Elasticity: Linking of Cardiovascular Risks, Pulse Pressure, Dementia, Aging, and Drug Targeting

Received: 08 December 2021;  Published: 29 March 2022;  doi: 10.21926/obm.neurobiol.2201117

Abstract

Cerebrovascular atherosclerosis, and several other cardiovascular (or "inflamm-aging" type) diseases, are more frequent and advanced in subjects with Alzheimer's disease compared with normal aging. In addition, the observed pathogenic link to dementia (and its associated cerebral microvascular damage) is readily explained by alterations of arterial elasticity. A therapeutic strategy to delay dementia could be based upon localized drug delivery, using lipid nanocarriers (i.e., biobased nanoemulsion technology), targ [...]

1106 8129

Open Access Original Research

A Cross-Sectional Study of COVID-19 Pandemic Impact on Postpartum Women's Level of Anxiety, Depression and Breastfeeding Duration

Received: 06 January 2023;  Published: 15 May 2023;  doi: 10.21926/obm.neurobiol.2302169

Abstract

Pregnancy and postpartum periods are known as sensitive periods in women’s life and COVID-19 pandemic seems to be worsening their mental health with major impacts on exclusive breastfeeding duration. Therefore, the present study aims to fill the gap in the literature by assessing the links between postpartum anxiety and depression symptoms and breastfeeding duration as well as the associated factors during the COVID-19 pandemic. A longitudinal prospective observational study was conducted between November and [...]

1146 8123

Open Access Review

Comparison of Compressed Air Flow Measurement Techniques for Industrial Energy Efficiency Enhancement

Received: 31 October 2024;  Published: 24 June 2025;  doi: 10.21926/aeer.2502024

Abstract

Across the industrial sector, compressed air is utilized as an easy-to-use and readily accessible tool in a variety of applications. This tool is commonly misunderstood as being more efficient than it is in reality. Air compression is energy intensive and thus both economically and environmentally costly. Compressed air typically only achieves around ~15% efficiency if judged by the energy delivered from the air, meaning approximately 5-6 kWh are wasted for every 1 kWh of useful work performed by compressed air. Du [...]

1305 8117

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