Table of Content

Open Access Review

Mycobacterium Tubercular Mediated Inflammation and Lung Carcinogenesis: Connecting Links

Received: 03 September 2022;  Published: 21 June 2023;  doi: 10.21926/obm.genet.2302183

Abstract

Lung cancer is a leading cause of death among all the cancer worldwide and it has the highest occurrence and mortality rates. Mycobacterium tuberculosis (MTB) induced tuberculosis has been known as one of the risk factors for lung carcinogenesis. The exact mechanism of MTB is understood to date. Several research and epidemiological studies about the link between tuberculosis and lung cancer exist. It has been proposed that tuberculosis causes chronic inflammation, which increases the risk of lung cancer by creating [...]

1349 8581

Open Access Original Research

A Mixed-Methods Pilot Study to Identify Facilitators Leading to Sustained Mindfulness Practice across the Perinatal Period

Received: 31 May 2022;  Published: 26 August 2022;  doi: 10.21926/obm.icm.2203038

Abstract

Many women experience depression and/or anxiety during pregnancy and/or the postpartum period. Mind-Body Interventions (MBIs) have shown great efficacy in the mitigation of these symptoms; however, there is limited research spanning the postpartum period and exploring long-term sustainability of mindfulness practice. Furthermore, little is known about specific facilitators that contribute to sustainability. The primary objective of this mixed-methods study is to use the Theory of Planned Behavior (TPB) framework to [...]

1648 8581

Open Access Communication

The Global Malnutrition Composite Score Quality Measure-Seize this Opportunity to Benefit Older Adult Care and Health Equity!

Received: 27 February 2023;  Published: 25 May 2023;  doi: 10.21926/obm.geriatr.2302237

Abstract

In August 2022, the Centers for Medicare and Medicaid Services (CMS) adopted its first-ever nutrition electronic clinical quality measure (eCQM), known as the Global Malnutrition Composite Score (GMCS) as part of the Inpatient Hospital Quality Reporting (IQR) Program. Starting in January 2024, hospitals can self-select to include the GMCS as one of three optional eCQMs for reporting. This article focuses on the importance of addressing malnutrition to improve the overall health of the aging population, reduce preve [...]

1323 8571

Open Access Original Research

Nature and City Sounds Influence Physiological and Psychological Markers in College Students

Received: 02 March 2023;  Published: 28 September 2023;  doi: 10.21926/obm.icm.2303039

Abstract

Worldwide, human population growth has led to a higher demand for urbanization. While this development is in accordance with our gregarious lifestyles, our availability and contact with nature has consequentially been minimized. The goal of this study was to evaluate whether sounds from nature versus urban environments affect vital signs (i.e., heart rate and respiration rate) and mood states of female college students. Emotional states were assessed using the Positive and Negative Affect Schedule (PANAS) questionn [...]

1589 8570

Open Access Technical Note

Towards Femtoscan-Assisted Analysis of Liquid Crystal Self-Organization on Different Polymer and Glass Surfaces for Lab-on-a-Chip and Lab-on-a-Dish Applications, Including Optofluidic and Flexoelectric Ones

Received: 27 December 2022;  Published: 29 May 2023;  doi: 10.21926/rpm.2302022

Abstract

In this paper, starting with an introductory review of the applications of liquid crystals and polymer-dispersed liquid crystal systems in (bio)sensors and microfluidics, the possibilities of visualizing self-organization products of liquid crystalline media or field-induced instabilities of liquid crystalline systems are considered. In particular illustrated cases, it is proposed to use FemtoScan software-containing metrological complexes to visualize instabilities in liquid crystalline systems and products of sel [...]

1968 8568

Open Access Review

Secondary Findings of Newborn Screening

Received: 16 April 2023;  Published: 31 August 2023;  doi: 10.21926/obm.genet.2303191

Abstract

The aim of newborn screening (NBS) program is to detect and manage treatable conditions in the early stages prior to the occurrence of long-term and irreversible sequalae. Phenylketonuria was the first screened disorder, but panels rapidly expanded after the introduction of tandem mass spectrometry technology into the program. Significant differences in the diseases screened by NBS were noted between programs in United States. Therefore, the recommended uniform screening panel was developed in 2006 to include a lis [...]

1613 8563

Open Access Original Research

The Social Justice and Human Rights Benefits of Domestic Renewable Energy

Received: 10 August 2022;  Published: 16 February 2023;  doi: 10.21926/aeer.2301021

Abstract

Focusing upon the United Kingdom reveals that centralised provisions of energy have historically failed to uphold standards of human rights. Even if a transition is made to renewable energy, existing centralised distribution systems cannot promise improvement. This work would recommend the transition to domestic renewables, whereby energy is harnessed and used in situ, as it may support the more desirable notion of social justice with regard to energy usage. Domestic renewables are likely to become an inevitability [...]

1326 8561

Open Access Short Report

Pediatric Thoracoscopic Repair of Diaphragmatic Herniation Following Liver Transplantation

Received: 09 August 2020;  Published: 05 January 2021;  doi: 10.21926/obm.transplant.2101131

Abstract

Diaphragmatic Hernia (DH) after Liver Transplantation (LT) is a rare complication with unclear pathophysiology. Among 261 LT, we recognized six DH during the post transplant period (2.30%). All patients with DH had received a left lateral segment (LLS) reduced graft. The mean graft weight was 340g with a mean graft-to-recipient body weight ratio (GBWR) of 4.20%. LLS grafts, a GBWR > 4%, previous abdominal surgery and direct trauma during surgery can be enumerated as potential risk factors for DH post-LT. These chil [...]

1483 8561

Open Access Original Research

The Significance of Key Proteins in the RAS Signaling Pathway: Implications for Cancer and Therapeutic Targets

Received: 18 January 2024;  Published: 24 May 2024;  doi: 10.21926/obm.genet.2402236

Abstract

The RAS signaling pathway is a crucial cell transduction pathway central to transmitting signals from outside the cell to the cell nucleus and influencing fundamental biological mechanisms like cell growth, division, and specialization. This signaling pathway has recently received much attention in scientific research because of its involvement in various diseases, especially carcinogenesis. Our study identified the significance of crucial proteins in the RAS signaling cascade in cancer development and progression. [...]

1273 8560

Open Access Original Research

Heavy Metal Concentration and Health Risk Assessment of Selected Fruits Sold in Jos Metropolis

Received: 27 February 2021;  Published: 12 May 2021;  doi: 10.21926/acr.2102013

Abstract

The present study investigated the level of heavy metals in selected fruits sold commonly in Jos, Nigeria. The fresh fruits (Avocado pear, Black currant, Egg Plant, Golden melon, and Soursop) were purchased from five major markets (Terminus, Farin Gada, Building materials, Bukuru, and Fobur) in Jos. Each fruit sample was collected in triplicate and analyzed using standard procedures. The concentration of heavy metals (Fe, Cu, As, Cd, Zn, Pb, Mn, and Cr) was determined using Graphite Furnace Atomic Absorption Spectr [...]

1522 8556

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