by Fernando Cabo  and Isaac Aguaristi

Received: 01 April 2020;  Published: 02 April 2020;  doi: 10.21926/obm.icm.2002018

by Elham Amjad  and Babak Sokouti

Received: 21 February 2025;  Published: 09 June 2025;  doi: 10.21926/obm.transplant.2502251

Graft rejection, early allograft dysfunction (EAD), and poor diagnostic accuracy are some of the challenges that still need to be addressed, even though liver transplantation (LT) has the potential to help patients with end-stage liver disease (ESLD) significantly. Traditional procedures, such as liver biopsies and liver function tests (LFTs), often fail to identify abnormalities early and with accuracy. Genomic RNA sequencing (RNA-Seq) has recently emerged as a powerful approach for identifying molecular markers o [...]

by Anita H Kelleher  and Angelos K Sikalidis

Received: 09 November 2020;  Published: 05 February 2021;  doi: 10.21926/obm.hg.2101056

The Mediterranean diet (MD) is considered one of the healthiest dietary patterns due to its rich provision of phytochemicals, antioxidants, vitamins, fiber, polyunsaturated, omega-3, and short-chain fatty acids through a variety of foods. The supply of such nutrients and bioactive components can support gut health and reduce systemic inflammation, with accumulating evidence from several human studies demonstrating the utility of the Mediterranean diet in the prevention of chronic and metabolic diseases. Further stu [...]

by Hossein Hosseinkhani

Received: 26 August 2024;  Published: 12 December 2024;  doi: 10.21926/rpm.2404027

Viral and non-viral vectors for nucleic acids (DNA/RNA) therapeutics are important in development of pharmaceutical industries. Although viral vectors have shown significant impact in transfection of DNA/RNA, but numerus studies have shown that non-viral vectors are also effective for the safe and targeted delivery of DNA/RNA to exact location in the body with high percentage of efficacy, safety, and low-immunogenicity. It is also important to protect the nucleic acids from degradation and large-scale production ca [...]

by Giuseppe Cocco

Received: 20 March 2020;  Published: 01 April 2020;  doi: 10.21926/obm.geriatr.2002112

by Mohammed Naveed

Received: 22 December 2022;  Published: 12 April 2023;  doi: 10.21926/rpm.2302015

Composite materials with aluminum as matrix material have a wider amplitude of large-scale applications in engineering. Some salient features of aluminum matrix composites are, low density, low thermal coefficient of performance and low weight and high strength. Among the various series of aluminum alloy, Al6061 have been widely used by researchers due to its outstanding properties particularly as they are heat treatable. Aluminum 6061 alloys have been reinforced with various particulate reinforcements such as sili [...]

by Ousman Bajinka  , Mamtuti Panneh  , Sang Mendy  , Amadou Barrow  , Haddy Bah  , Lamarana Jallow  , Jarry Jallow  , Kaddy Drammeh  , Kaddijatou Kah  , Oulimatou Lateef  , Mariama A Bah  , Isatou K Sillah  , Fatoumata Bah  , Nyima Ceesay  , Mariama Jaiteh  and Yurong Tan

Received: 31 August 2024;  Published: 08 April 2025;  doi: 10.21926/rpn.2502006

The adverse effects of maternal passive smoking during pregnancy on offspring health remain understudied in sub-Saharan Africa, particularly in The Gambia, where smoke-free regulations are limited. To determine the prevalence of maternal passive smoking (MPS) during pregnancy and investigate its associations with adverse pregnancy outcomes and offspring health complications in The Gambia. A cross-sectional study was conducted in February 2023 among 401 mothers with children under 5 years in urban and rural regions [...]

by Sai Batchu  , Michael J. Diaz  , Lauren Ladehoff  and Brandon Lucke-Wold

Received: 27 September 2022;  Published: 03 February 2023;  doi: 10.21926/obm.neurobiol.2301153

Genes encoding for proteins associated with the plasma membrane, referred to as the membranome, have long been recognized to play an important role in the development and maintenance of glioblastoma multiforme (GBM). GBM cell lines are commonly used to mimic tumors for in vitro experiments, but the extent to which they resemble GBM tumors in relation to the membranome is unclear. The present study explores the resemblance of GBM cell lines to primary tumors regarding membranome expression. Gene expression data was [...]

by Andrey Koptyug  , Yurij Sukhovei  , Elena Kostolomova  , Irina Unger  and Vladimir A. Kozlov

Received: 14 April 2023;  Published: 22 December 2023;  doi: 10.21926/obm.geriatr.2304263

Understanding processes related to human aging and rejuvenation relies on experimental data and advanced models operating at different levels. There are several existing conceptual and specific modeling approaches. However, one of the existing tasks is compiling generic models linking properties at cell and cell-element levels to properties at systemic levels - tissue, organ, and whole body. One of the critical issues in the relevant models is the enormity of interacting components at the cell and sub-cell levels n [...]

by Marco Minella  , Khan M.G. Mostofa  , Cong-qiang Liu  and Davide Vione

Received: 05 September 2019;  Published: 21 January 2020;  doi: 10.21926/obm.acr.2001004

Superoxide, produced photochemically as well as microbially, is an important reactant present in seawater and a major source of hydrogen peroxide. Superoxide decay may occur through catalyzed or uncatalyzed dismutation forming H2O2 and O2, through oxidation to O2, or through reduction into H2O2. Under definite circumstances, the redox processes that are different from dismutation could produce or consume H+, thereby altering the pH of seawater. In order to alter the pH, these processes have to involve, together wit [...]