Table of Content

Open Access Original Research

The P2X7 Receptor Antagonist AZ10606120 Does Not Alter Graft-Versus-Host Disease Development and Increases Serum Human Interferon-γ in a Humanized Mouse Model

Received: 06 June 2022;  Published: 06 September 2022;  doi: 10.21926/obm.transplant.2203166

Abstract

Allogeneic hematopoietic stem cell transplantation is a curative therapy for hematological malignancies, but its efficacy is limited by graft-versus-host disease (GVHD). This life-threatening disorder develops when donor (graft) immune cells cause inflammatory damage to recipient (host) tissues. The immune cell receptor channel P2X7 and its ligand adenosine 5’-triphosphate (ATP) have been implicated in GVHD pathogenesis. Therefore, this signaling axis represents a potential therapeutic target. This study aime [...]

1380 9557

Open Access Opinion

The Conundrum of High Body Mass Index in Kidney Transplant Patients

Received: 19 October 2018;  Published: 19 November 2018;  doi: 10.21926/obm.transplant.1804026

Abstract

Obesity is on the rise and the number of end stage renal disease patients who are obese parallel this trend. There is no universally accepted guideline for wait-listing end stage renal disease obese patients in order to reduce surgical complications and improve survival of the kidney graft. Criteria for acceptance are variable among transplant centres, as do post-transplant policies. Careful risk assessment to maximise the benefits of the limited organ donor resource must be undertaken prior to waitlist an obese ki [...]

1507 9552

Open Access Original Research

Modulation of Excitability of Spinal Neural Functions by Acupoint Stimulation Physical Therapy at LU5 (Chize) in Three Hemiplegic Patients with Cerebrovascular Disease

Received: 21 January 2017;  Published: 20 February 2017;  doi: 10.21926/obm.icm.1701001

Abstract

(1) Background: Acupoint stimulation physical therapy (ASPT) is a novel method of physical therapy that combines physical and acupuncture methods. This study aimed to examine the effect of ASPT in three hemiplegic patients with cerebrovascular disease using F-wave as a measure of the excitability of spinal neural function. (2) Methods: Subjects included three hemiplegic patients with cerebrovascular disease who presented with three types of neurological findings. All patients had moderate hypertonic muscles on the [...]

1779 9544

Open Access Original Research

Non-Isothermal Compressible Flow Model for Analyzing the Effect of High CO2 Inlet Flow Rate on Particle Size in a Supercritical Antisolvent Process

Received: 17 December 2022;  Published: 18 April 2023;  doi: 10.21926/jept.2302016

Abstract

In this work with CFD simulations, the evaluation of the supercritical anti-solvent (SAS) process for producing nanoparticles from an expanded solution of ethanol/solute in carbon dioxide is reported. The influence of the solution and antisolvent flow rates on mean particle size, the flow dynamic, and the supercritical mixture's jet velocity must be well established in the literature and analyzed. The high flow rate of the anti-solvent resulted in increased mean particle sizes for all studied cases. At the lowe [...]

1378 9541

Open Access Original Research

Teachers on Self-Care

Received: 19 November 2024;  Published: 07 April 2025;  doi: 10.21926/obm.icm.2502017

Abstract

Teachers face at-work risk factors including compassion fatigue, burnout, dealing with violence, and a teacher shortage. A review of the literature shows that self-care can have positive benefits that mitigate and help to buffer these at-work risk factors This study examines teachers’ stories of self-care. The data suggests that self-care is a positive practice for teachers professionally and personally.

1331 9537

Open Access Original Research

The Use of Sulfur Waste to Protect Against Corrosion of Metal Implants

Received: 24 March 2021;  Published: 15 June 2021;  doi: 10.21926/rpm.2102024

Abstract

Metal parts of endoprosthesis have a detrimental effect on the bones that come into contact with them and on the entire body of the patient. Coating them with biocompatible layers (hydroxyapatite and bioglass) has not yet brought about permanent results. In this study, the author showed the possibility of using a binder containing sulfur waste for this purpose. The sulfur binder is used industrially in electrical engineering and construction applications. The chemical properties of elemental sulfur indicate that it [...]

1950 9537

Open Access Research Article

Estimation of the Return Periods in Hydrology

Received: 26 September 2022;  Published: 08 December 2022;  doi: 10.21926/aeer.2204049

Abstract

A filtered Poisson process is proposed as a model for river flows. With the help of real-life data, the model parameters are estimated. Mathematical formulae are derived in order to estimate the various return periods of the river. An application to two rivers shows that the point estimates are very close to the corresponding values computed by hydrologists, based on historical data. Moreover, by modifying the values of the parameters in the model, we can see the potential effects of climate change on the return pe [...]

2282 9530

Open Access Original Research

Associations between Health-Related Behaviours, Well-Being, and Academic Performance of Secondary School Students with Special Educational Need: A Secondary Analysis

Received: 24 October 2022;  Published: 06 March 2023;  doi: 10.21926/rpn.2301005

Abstract

Health-related behaviours (HRBs) have been considered one of the most critical public health issues, especially for those with special educational needs (SEN). Previous research suggests that health-related behaviours are highly likely to impact well-being and academic achievement. Diet is a crucial health-related behaviour that needs to be investigated along with factors such as sleep and exercise. The present study used data from the Cornish Academies Project, and secondary analyses were conducted to investigate [...]

1440 9529

Open Access Review

Comparison of Compressed Air Flow Measurement Techniques for Industrial Energy Efficiency Enhancement

Received: 31 October 2024;  Published: 24 June 2025;  doi: 10.21926/aeer.2502024

Abstract

Across the industrial sector, compressed air is utilized as an easy-to-use and readily accessible tool in a variety of applications. This tool is commonly misunderstood as being more efficient than it is in reality. Air compression is energy intensive and thus both economically and environmentally costly. Compressed air typically only achieves around ~15% efficiency if judged by the energy delivered from the air, meaning approximately 5-6 kWh are wasted for every 1 kWh of useful work performed by compressed air. Du [...]

1628 9528

Open Access Research Article

A Methodology to Estimate Net Proton: Phosphorus Co-Adsorption Ratios for Acidic Soils

Received: 07 November 2019;  Published: 13 April 2020;  doi: 10.21926/acr.2002005

Abstract

Despite extensive research, the behaviour of the key nutrient element, phosphorus (P), in soil is not yet fully understood. This study focussed on the outstanding issue of the co-adsorption of protons (H+) and P by soils. We developed a congruent set of measures to determine the net H+:P co-adsorption ratio and tested it on goethite, for which a ratio of 1.6:1 had been estimated under CO2-free conditions for additions of NaH2PO4. Under our conditions, and using additions of KH2PO4, the net H+:P co-adsorption ratio [...]

1507 9525

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