Table of Content

Open Access Review

Pneumocystis as a Co-Factor in Pulmonary Diseases

Received: 02 November 2018;  Published: 27 December 2018;  doi: 10.21926/obm.genet.1804057

Abstract

Pneumocystis causes life-threatening pneumonia in immunocompromised populations. More recently it has been implicated as a co-factor in a number of chronic lung diseases including chronic obstructive pulmonary disease (COPD), severe asthma, and cystic fibrosis (CF). In this review, we will examine the current literature regarding Pneumocystis and lung diseases in the HIV-infected patients and non-HIV immunocompromised populations, and the barriers to prophylaxis and treatment in these patients. Trimethoprim sulfame [...]

2022 9588

Open Access Case Report

Ectopic Pelvic Kidney with Anomalous Vascular Supply during Deceased Organ Procurement – Case Report

Received: 13 August 2018;  Published: 21 September 2018;  doi: 10.21926/obm.transplant.1803020

Abstract

Even though renal ectopia is common, there have been very few reports of these kidneys being used for transplantation. The concerns with using such kidneys are subnormal function, ureteral anomalies and complications and anomalous arterial supply which makes arterial reconstruction challenging. Majority of reports are for use in living donor transplantation where good preoperative imaging is available. There is very scant literature reporting use of ectopic pelvic kidneys from deceased donors. We report a case of a [...]

1775 9588

Open Access Concept Paper

Using Structured Compassion Focused Formulations Towards Change in Couples and Organisations

Received: 08 February 2022;  Published: 20 July 2023;  doi: 10.21926/obm.icm.2303030

Abstract

The current article describes the application of the Compassion Focussed (CF) formulation to the interaction between individuals and their social context. The standard CF formulation [1] would see the person’s fears as inadvertently reinforced by their attempts to cope with the underlying issue. However, sometimes such attempts to cope can also reinforce the fears of another person or party. Interpersonal CF formulations could provide a compassionate, non-blaming way of enlightening people in their interactions to [...]

1380 9581

Open Access Original Research

Generalized Resistance Resources in the Time of COVID-19: The Role of Sense of Coherence and Resilience in the Relationship between COVID-19 Fear and Loneliness among Schoolteachers

Received: 30 April 2022;  Published: 15 August 2022;  doi: 10.21926/obm.neurobiol.2203130

Abstract

Fear has been the most common emotional response to the COVID-19 pandemic, and excessive fear is associated with various indices of psychological distress, particularly loneliness. Although most people have experienced pandemic-related fear and distress, certain groups who are on the front of service provision have experienced the pandemic in distinct ways, owing to its impact on the nature of their work. Schoolteachers represent one such group; therefore, it is imperative to identify resources that can safeguard a [...]

1672 9579

Open Access Research Article

Developing a Compassion Focused Supervision Model for Senior Leaders in Education

Received: 22 March 2024;  Published: 11 June 2024;  doi: 10.21926/obm.icm.2402033

Abstract

This article describes the development and delivery of a novel model of supervision for senior teachers in schools, informed by Compassion Focused Therapy (CFT). It explores whether this model can be considered acceptable and valuable to senior teachers, and is able to be delivered by multiple supervisors using a manual. Surveys, interviews, and focus groups were used to gather feedback about the value and impact of the supervision. Data were gathered from 39 senior teachers across three phases to assess feedback o [...]

1689 9578

Open Access Research Article

Restoration of Reservoir Caprock: Long-Term Wellbore Sealing and Abandonment through Zeolite Enhanced Cement

Received: 21 March 2022;  Published: 29 April 2022;  doi: 10.21926/aeer.2202017

Abstract

Oil and gas wellbores that are drilled into the earth’s crust need to be plugged and abandoned, to restore the geological seals once they are no longer producing. The main aim of Plugging and abandonment (P&A) is to ensure that there is no leakage of hydrocarbons into the environment. Since offshore P&A is challenging due to subsurface temperature and pressure conditions, testing zeolite as an additive for improvement of cement properties is an intriguing research topic. This initial research aims to [...]

1533 9566

Open Access Editorial

MOF-based Heterogeneous Catalysis: A Frontier in Sustainable Chemical Transformations

Received: 02 December 2024;  Published: 05 December 2024;  doi: 10.21926/cr.2404014

1785 9566

Open Access Research Article

Integrated Oncology in an Integrated Medicine Hospital in Pitigliano (Grosseto, Italy)

Received: 29 September 2018;  Published: 01 February 2019;  doi: 10.21926/obm.icm.1901008

Abstract

Background: Complementary medicines (CM), including homeopathy, acupuncture, and traditional Chinese medicine, have been introduced for cancer patients undergoing chemotherapy and radiotherapy treatment in the Pitigliano Hospital Centre of Integrated Medicine in order to minimize the side effects of these treatments, which improves quality of life and adherence to conventional therapies. Methods: Cancer patients (240) were enrolled in an integrated care model offering a comprehensive protocol including homeopathy a [...]

1940 9565

Open Access Original Research

A Policy and Evaluation Framework for Sustainable Transitions - An Energy Policy Approach

Received: 15 May 2023;  Published: 15 January 2024;  doi: 10.21926/aeer.2401003

Abstract

The climate change and the social crisis launched the basis for the policy discussion about future trajectories of development and sustainability. Innovation policies are expected to promote the transformation of complex socio-technical systems and call for fundamentally different societal production and consumption patterns. This is strictly associated with energy systems and energy policies. A policy framework was conceptualized considering three levels approach: the policy shape at the micro level, the policy co [...]

1409 9564

Open Access Original Research

The P2X7 Receptor Antagonist AZ10606120 Does Not Alter Graft-Versus-Host Disease Development and Increases Serum Human Interferon-γ in a Humanized Mouse Model

Received: 06 June 2022;  Published: 06 September 2022;  doi: 10.21926/obm.transplant.2203166

Abstract

Allogeneic hematopoietic stem cell transplantation is a curative therapy for hematological malignancies, but its efficacy is limited by graft-versus-host disease (GVHD). This life-threatening disorder develops when donor (graft) immune cells cause inflammatory damage to recipient (host) tissues. The immune cell receptor channel P2X7 and its ligand adenosine 5’-triphosphate (ATP) have been implicated in GVHD pathogenesis. Therefore, this signaling axis represents a potential therapeutic target. This study aime [...]

1380 9560

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