by Karen Sermon

Received: 11 August 2017;  Published: 26 October 2017;  doi: 10.21926/obm.genet.1704009

The main aim of PGS has always been to improve IVF outcome, especially in patient groups assumed to have higher rates of chromosomally abnormal embryos, such as patients of advanced maternal age. In that sense, PGS is quite different from other types of screening as discussed in other papers in this issue.Today it bears no doubt that blastocysts found to be uniformly aneuploid in a biopsy will fail to implant, or worse, will implant and lead to a pregnancy and birth carrying a major chromosomal abnormality, such as [...]

by Mariarosaria Angrisano  and Francesco Fabbrocino

Received: 02 August 2022;  Published: 11 January 2023;  doi: 10.21926/rpm.2301005

Nowadays, the challenge of climate change and “ecological transition” is substantially an “energy challenge” for every city, which is supposed to become as “energetically self-sufficient” as possible. The construction sector is one of the main contributors to the effects of climate change, starting from the production of materials to the use phase of buildings to their demolition. Recent innovations in sustainable/circular design are related to using “new materials." According to this perspective, nanomaterials are [...]

by Renata Lemonica  , Isabela Almeida Cunha  , Jéssica Layane Costa Melo  , Sandra Regina Caram  , José Eduardo Fuser Bittar  and Karina Pavao Patricio

Received: 23 March 2024;  Published: 31 July 2024;  doi: 10.21926/obm.icm.2403044

Homeopathy has shown promise in fighting epidemics, leading to potential applications in the COVID-19 clinical cases. To assess the impact of add-on individualized homeopathic medicinal products (IHMP) on improving clinical outcomes and time to medical discharge in COVID-19 patients, a prospective, double-blind, randomized, placebo-controlled, parallel-group exploratory clinical trial was conducted in a São Paulo state municipality, Brazil, between February and July 2021. 82 (unvaccinated) patients with conf [...]

by Ami Rokach  and Karishma Patel

Received: 27 July 2023;  Published: 13 October 2023;  doi: 10.21926/obm.icm.2304042

The healthcare industry is the largest and fastest growing industry in the world; however, being a part of the healthcare system involves being at an increased risk of experiencing mental health problems, loneliness, stress, and increased susceptibility to experiencing compassion fatigue related to the emotional wear associated with providing patient-centered care. Healthcare workers include, but are not limited, to physicians, nurses, allied health professionals, and psychologists. Often, healthcare workers place [...]

by Oleksandr Skrylnyk  , Emilie Courbon  , Nicolas Heymans  and Marc Frère

Received: 18 December 2020;  Published: 14 April 2021;  doi: 10.21926/jept.2102017

Hybrid solar thermal systems are considered to be a promising solution for delivering clean thermal energy for the building sector, especially while combining them with other renewable energy sources. Usually, solar energy production does not match the thermal energy demand, and hence the energy storage must be integrated. Thermochemical energy storage is adapted particularly to be used along with solar thermal applications. In this article, the design of the combined solar thermochemical energy storage system is p [...]

by Ivan V. Maksimovich

Received: 24 July 2021;  Published: 21 October 2021;  doi: 10.21926/obm.icm.2104036

The present research is dedicated to the application of intracerebral laser PBMT for the treatment of the consequences of ischemic stroke. The effectiveness of intracerebral laser PBMT is compared to that of the conservative therapy methods. Recent studies have demonstrated a high potential of laser technology PBMT in the treatment of various ischemic lesions of the brain. A total of 836 patients who had experienced ischemic strokes of different degrees of severity in the period ranging from 6 months to 6 years pri [...]

by Reinhard Haas  , Marina Siebenhofer  , Jakob Lederer  and Amela Ajanovic

Received: 24 June 2022;  Published: 27 September 2022;  doi: 10.21926/jept.2203030

Today, the building sector poses a major problem concerning fossil fuel energy consumption and the corresponding emissions of local pollutants and global greenhouse gases (GHG). In addition, an increasing number of people are living in urban areas, and it is becoming challenging to provide the necessary living space and energy for heating in fast-growing cities. Currently, urban areas host approximately 50 % of the global population and generate 70 % of GHG. The core objective of this study is to analyze the histor [...]

by Laura Alonso Canal  , Cecilia Paredes Mercado  , María José Quiles Blanco  and Marco Motta Calderón

Received: 01 April 2019;  Published: 14 May 2019;  doi: 10.21926/obm.neurobiol.1902028

Lyme disease is a spirochetal illness transmitted primarily through the bite of ticks. The disease has a broad spectrum of comorbid conditions including osteoarticular, cardiovascular, and neurological involvement. In addition, clinical variability depends on the age of affected individuals. The Center for Disease Control recognizes the disease as an epidemic and mentions it to be a major morbidity burden in our environment because of the frequent lack of diagnosis and early treatment. Scientific literature mention [...]

by Shashya Wijesinghe  and Elizabeta B. Mukaetova-Ladinska

Received: 03 March 2024;  Published: 10 May 2024;  doi: 10.21926/obm.geriatr.2402279

In the UK, 25,000 people from ethnic minority background live with dementia. Although dementia associated risk factors are common amongst South Asians, they tend to present at services later and when in crisis. This review explores UK South Asian communities perception of dementia to understand factors impacting their decision to seek help. Search terms assisted by the PICO strategy were inputted into five databases and ten qualitative papers identified. Meta-ethnography methodological framework was implemented for [...]

by Irina Udina  , Yurii Vasiliev  , Vladimir Volobuyev  , Olga Gulenko  and Alesya Gracheva

Received: 24 December 2021;  Published: 27 June 2022;  doi: 10.21926/obm.genet.2202158

In this study, we investigated VNTR polymorphisms in intron 2 of the IL1RN gene (rs2234663) and intron 3 of the IL4 gene (rs8179190) related to the development of caries in school children (N = 196) with mixed bite dentition from Krasnodarskii Krai. The genotypes A1/A1 and L/L (L-"long" alleles) (rs2234663) provided resistance to the most intensive form of dental caries. The groups of children with DFC (decompensated form of caries) were significantly different from the pooled group SFC (subcompensated form of cari [...]