by Courtney Tate  , Jason P Butler  , Cameron Curley  , Siok-Keen Tey  , Glen A Kennedy  and Ashleigh P Scott

Received: 23 June 2020;  Published: 23 October 2020;  doi: 10.21926/obm.transplant.2004121

Acquired Severe Aplastic Anaemia (SAA) is a rare bone marrow failure syndrome, for which allogeneic haematopoietic stem cell transplant (HSCT) is a proven curative therapy. Despite excellent outcomes for matched sibling SAA recipients in terms of engraftment and survival, HSCT remains highly challenging in older matched-unrelated-donor (MUD) recipients, due to increased non-relapse mortality (NRM) from causes such as graft versus host disease (GVHD), organ failure and infection. We sought to evaluate our local HSCT [...]

by Petr A. Fedotov  , Maria A. Simonenko  , Yulia V. Sazonova  , Mariya A. Bortsova  , Artem N. Kostomarov  and Mariya Yu. Sitnikova

Received: 01 February 2019;  Published: 05 August 2019;  doi: 10.21926/obm.transplant.1903077

Background: To estimate the survival of patients in the heart transplantation waiting list (HTx WL) at Almazov National Medical Research Centre (V.A. Almazov NMRC), Saint-Petersburg, Russia, from 2010 to 2017 and to define risk factors for death among these patients. Methods: It was a single-center retrospective study involving 151 patients with advanced chronic heart failure (CHF) in the HTx WL. Results: Mortality in the HTx WL for the period 2010-2017 was found to decrease. Based on the results of constructing th [...]

by Qing Ye  , Yijen L. Wu  , Lesley M. Moley  , Parker H. Mills  , Fang-Cheng Yeh  , Haosen Zhang  , Danielle F. Eytan  , Li Liu  , T. Kevin Hitchens  and Chien Ho

Received: 07 January 2019;  Published: 29 August 2019;  doi: 10.21926/obm.transplant.1903083

Background: Cardiac allograft vasculopathy (CAV) remains a major obstacle to long-term heart allograft survival. A number of studies show that immune mechanisms are involved in CAV. Using non-invasive cellular MRI (CMRI) to explore indicators of CAV lesions and characterize its development could provide new insights into the target immune cells that are responsible for the progression of CAV and reveal early markers of the disease before irreversible changes occur. Methods and Results: Rat heart transplant allograf [...]

by Mariarosaria Angrisano  and Francesco Fabbrocino

Received: 02 August 2022;  Published: 11 January 2023;  doi: 10.21926/rpm.2301005

Nowadays, the challenge of climate change and “ecological transition” is substantially an “energy challenge” for every city, which is supposed to become as “energetically self-sufficient” as possible. The construction sector is one of the main contributors to the effects of climate change, starting from the production of materials to the use phase of buildings to their demolition. Recent innovations in sustainable/circular design are related to using “new materials." According to this perspective, nanomaterials are [...]

by Reinhard Haas  , Marina Siebenhofer  , Jakob Lederer  and Amela Ajanovic

Received: 24 June 2022;  Published: 27 September 2022;  doi: 10.21926/jept.2203030

Today, the building sector poses a major problem concerning fossil fuel energy consumption and the corresponding emissions of local pollutants and global greenhouse gases (GHG). In addition, an increasing number of people are living in urban areas, and it is becoming challenging to provide the necessary living space and energy for heating in fast-growing cities. Currently, urban areas host approximately 50 % of the global population and generate 70 % of GHG. The core objective of this study is to analyze the histor [...]

by Marco Antonio Gaya de Figueiredo  , Luiza G. dos Santos  , Rômulo Luciano Nascimento  and Harrison Lourenço Corrêa

Received: 18 April 2024;  Published: 11 November 2024;  doi: 10.21926/jept.2404020

Hydrogen is crucial in various industrial sectors and can be obtained through different synthesis routes. However, a significant portion of its production still relies on chemical processes involving fossil fuels, resulting in hydrogen and the generation of greenhouse gases (GHGs) as the final byproduct. In alignment with the goals of the 2030 Agenda, where countries commit to implementing energy transition, hydrogen obtained through a green route has been increasingly explored by governmental and academic entities [...]

by Robert Medina  , Akanksha Dave  , Candice Keogh  , Jordan Bartfield  , Franco Estenssoro  , Melissa Fraga  and Brandon Lucke-Wold

Received: 28 February 2025;  Published: 21 July 2025;  doi: 10.21926/obm.neurobiol.2503292

This review examines a multimodal approach that integrates advanced neuroimaging, biofluid biomarkers, and innovative rehabilitation strategies for the optimized diagnosis and recovery of traumatic brain injury (TBI). TBI remains a critical public health challenge due to its high incidence and diverse, long-lasting morbidities. Conventional diagnostic methods often lack the sensitivity to detect subtle injuries, and current prognostic models are limited by the heterogeneity of TBI. Emerging neuroimaging techniques, [...]

by Tahereh Fatemian  and Ezharul Hoque Chowdhury

Received: 29 March 2019;  Published: 15 August 2019;  doi: 10.21926/obm.genet.1903090

Introduction of biocompatible ingredients into nano-material formulations has been studied as a strategy for the enhancement of the pharmacokinetics as well as pharmacodynamics of the final product. With the aim of enhancing drug loading and the ultimate efficacy, incorporation of Bovine Serum Albumin (BSA) into carbonate apatite (CA) nanoparticles structure was employed in the present study. As a result of BSA embedding in the CA formulation, approximately three-times higher loading efficiency was achieved for pac [...]

by Sophia Demeneopoulou  , Marianna Mantzorou  , Petra Mandysova  , Nikoletta Margari  , Eleni Dokoutsidou  , Aggeliki Tsiligianni  , Chrysoula Tsiou  and Theodoula Adamakidou

Received: 09 October 2020;  Published: 02 April 2021;  doi: 10.21926/obm.geriatr.2102165

Dysphagia may become a threatening condition if not diagnosed and treated at an early stage. Healthcare professionals require simple, rapid, and reliable tools for the immediate evaluation of dysphagia in their daily clinical practice. The aim of the present study was the translation and validation of the “Brief Bedside Dysphagia Screening Test-Revised (BBDST-R)” tool in the Greek language in a sample of patients with neurological disorders. The present study was designed as a cross-sectional study cond [...]

by Ivan V. Maksimovich

Received: 24 July 2021;  Published: 21 October 2021;  doi: 10.21926/obm.icm.2104036

The present research is dedicated to the application of intracerebral laser PBMT for the treatment of the consequences of ischemic stroke. The effectiveness of intracerebral laser PBMT is compared to that of the conservative therapy methods. Recent studies have demonstrated a high potential of laser technology PBMT in the treatment of various ischemic lesions of the brain. A total of 836 patients who had experienced ischemic strokes of different degrees of severity in the period ranging from 6 months to 6 years pri [...]