by Jose L. Tapia  and Jon Andoni Duñabeitia

Received: 31 March 2023;  Published: 10 October 2023;  doi: 10.21926/obm.neurobiol.2304187

Driving is a critical aspect of personal mobility and autonomy, but ensuring road safety requires a comprehensive evaluation of driving abilities beyond self-reported behaviors and practical skills. This article emphasizes the importance of cognitive assessment in determining fitness to drive and explores the potential benefits of using digital tools for such evaluations to enhance road safety. Implementing these digital tools does come with challenges, such as unfamiliarity with digital cognitive reviews for some [...]

by Leila Naseri  , Mohsen Akbaribazm  and Mozafar Khazaei

Received: 06 February 2024;  Published: 04 July 2024;  doi: 10.21926/obm.genet.2403248

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy causing non-ovulation infertility in women. Women with PCOS have higher levels of luteinizing hormone (LH), testosterone, cholesterol and triglycerides but, in contrast, lower levels of follicular stimulating hormone (FSH) and sex hormone-binding globulin (SHBG) compared with healthy counterparts. Because of the limitations of human studies, animal models of PCOS have been developed to identify appropriate therapeutics and to explore their mechanism [...]

by Athina Chasapi  , Konstantinos Balampanis  , Anna Tanoglidi  , Eleni Kourea  , George I. Lambrou  , Vaia Lambadiari  , Fotios Kalfarentzos  , Erifili Hatziagelaki  , Maria Melachrinou  and Georgia Sotiropoulou-Bonikou

Received: 28 January 2019;  Published: 22 May 2019;  doi: 10.21926/obm.hg.1902020

(1) Background: A great number of inflammatory mediators and metabolic biomarkers have been shown to contribute to the development and progression of obesity-induced pathologies, including insulin resistance and nonalcoholic fatty liver disease (NAFLD). Many of those mediators are either targets or activators of nuclear factor-κappa B (NF-κB), which is a key transcription factor and plays a pivotal role in the homeostasis and the regulation of inflammatory signaling pathways in the liver. (2) Methods: Our study po [...]

by António A. L. Ferreira  , Pedro Delgado  , Helena Parauta  , Charles V. Löwenström  and Joana O. Almeida

Received: 30 September 2022;  Published: 11 January 2023;  doi: 10.21926/rpm.2301004

In the context of inspection and maintenance actions for beach walkways in the North of Portugal, some samples of wood used in their construction were collected – the Pinus sylvestris wood, widely applied in the country. The sustainability of the beach walkways over natural coastal areas is very dependent on their material durability. One of the main problems of the timber used to build those structures is its behavior under wet-drying cycles. For that reason, this work aimed to simulate the effects of weathering o [...]

by Herbert B. Allen

Received: 30 December 2019;  Published: 19 February 2020;  doi: 10.21926/obm.geriatr.2001107

A pathway which highlighted spirochetes (Borrelia burgdorferi and dental treponemes) that made biofilms which led to Alzheimer’s disease has recently been promulgated. All the Alzheimer’s disease, on which this pathway was based, had been specifically confirmed both clinically and pathologically. This current work will show putative and plausible individual pathways that were studied. First and foremost, intracellular spirochetes make biofilms and concurrently make beta amyloid; this has been shown in v [...]

by Marcel Torrent

Received: 16 November 2022;  Published: 15 May 2023;  doi: 10.21926/aeer.2302032

This article quantifies the recycling potential of the metallic materials that make up three-phase induction motors. The data on the use of electric motors by type and power determines that the most significant recycling potential lies in this low-voltage motor which powers up to 75 kW. The work aims to show the possibility of such recycling in the European Union (EU). The metals used to make the various parts of the induction motor and the main recycling methods that allow their reuse are listed. It evaluates whic [...]

by Rosaria Ferreri  , Simonetta Bernardini  , Franco Cracolici  and Francesca Bechini

Received: 29 September 2018;  Published: 01 February 2019;  doi: 10.21926/obm.icm.1901008

Background: Complementary medicines (CM), including homeopathy, acupuncture, and traditional Chinese medicine, have been introduced for cancer patients undergoing chemotherapy and radiotherapy treatment in the Pitigliano Hospital Centre of Integrated Medicine in order to minimize the side effects of these treatments, which improves quality of life and adherence to conventional therapies. Methods: Cancer patients (240) were enrolled in an integrated care model offering a comprehensive protocol including homeopathy a [...]

by Sheri Tran  and Mark M Fuster

Received: 16 July 2017;  Published: 12 September 2017;  doi: 10.21926/obm.transplant.1703004

The risk for developing a variety of malignancies is significantly elevated in the setting of lung transplantation. Malignancy remains among the three major causes of death in post-transplant recipients, and the relatively high risk of cancer development as well as metastatic aggression pose special threats to this population due to the need for continued immunosuppression. A variety of risks such as tobacco use and inflammatory lung diseases that led to the lung pathology prompting lung transplantation, in additio [...]

by Peter Leary  and Peter Malin

Received: 30 November 2020;  Published: 19 March 2021;  doi: 10.21926/jept.2101013

In interest of accurately modelling wellbore production in convective geothermal systems, we draw attention to two approaches to numerical simulation of crustal fluid flow. The historical "strong" approach simulates the fluid mass conservation condition on a localised finite difference mesh approximation to poroelastic continua. The more flexible "weak" approach globally enforces fluid mass conservation by in effect integrating over all numerical mesh cells. Strong formulation crustal flow simulation emerged from n [...]

by Stefan Hardy Lung  and Thomas Lung

Received: 30 November 2024;  Published: 14 April 2025;  doi: 10.21926/obm.geriatr.2502307

Cellular senescence (aging) is a physiological process that plays a role in tissue remodeling, wound healing, and embryogenesis. Prolonged senescence of cells can have detrimental effects and trigger a secretory phenotype (SASP, senescence-associated secretory phenotype), degenerative disorders, cancer, and age-related diseases. Suitable biomarkers and a range of different laboratory methods are used to investigate these complex relationships in vitro and in vivo. Since a universal biomarker for cell senescence has [...]