Table of Content

Open Access Original Research

Theoretical investigation of the single and double ionization spectra of M(CO)6, M = W and Cr

Received: 26 April 2020;  Published: 14 December 2020;  doi: 10.21926/acr.2004010

Abstract

In this work, we study the single and double ionization spectra of the , with complexes by applying the four-component algebraic diagrammatic construction and Fock-space coupled cluster methods to extend earlier studies based on less demanding approaches. The computed single and double ionization potentials are in good agreement comparing with the available experimental results. The electronic structures of the cationic molecular systems are carefully investigated by computing accurately single and double ionizatio [...]

1489 7217

Open Access Original Research

Effective Photogeneration of Singlet Oxygen and High Photocatalytic and Antibacterial Activities of Porous Mn-Doped ZnO-ZrO2 Nanocomposites

Received: 06 April 2024;  Published: 03 July 2024;  doi: 10.21926/cr.2403008

Abstract

Disperse porous Mn-doped ZnO-ZrO2 nanocomposites were prepared using the facile polymer-salt method. The effect of Mn content on the crystal structure, composite morphologies, their ability to photogenate the singlet oxygen, luminescence properties, and bactericidal activities were studied. The crystal structure and morphology of these materials were investigated using XRD and SEM analysis. It was found that obtained nanocomposites consist of small (~9 nm) hexagonal ZnO and fine ZrO2 crystals and the embedding of M [...]

1131 7216

Open Access Original Research

Farmer Stress & Coping: Qualitative Study from Hawaiʻi

Received: 18 June 2024;  Published: 23 December 2024;  doi: 10.21926/obm.icm.2404070

Abstract

This qualitative study explores the mental health challenges faced by Hawaiʻi farmers and allied agricultural producers, focusing on the main stressors they encountered and the coping mechanisms they employed. Through interviews with 77 farmers across all four counties, data revealed that significant stressors for Hawaiʻi farmers were legislative and policy issues, financial and economic concerns, as well as pests and diseases. Farmers employed various coping strategies to mitigate stress, primarily along the lines [...]

897 7209

Open Access Review

Diabetes and Sarcopenia: Intersection of Co Morbid Conditions

Received: 09 July 2024;  Published: 20 February 2025;  doi: 10.21926/obm.geriatr.2501299

Abstract

Sarcopenia is more common in persons with type 2 diabetes mellitus (T2DM) than in persons without diabetes. There is overlap of some pathophysiologic features of sarcopenia and T2DM. In addition, the risk for sarcopenia is associated with common complications of T2DM including renal disease, cardiovascular disease and neuropathy. Glycemic control in T2DM may have some benefits on sarcopenia. The specific effects of glucose lowering agents on sarcopenia suggest that metformin, insulin, thiazolidinediones and GLP1 re [...]

1301 7201

Open Access Original Research

Resilience in Adversity: COVID-19 Pandemic Challenges in Diminishing Entrepreneurial Intentions and Business Startups

Received: 13 November 2023;  Published: 11 March 2024;  doi: 10.21926/obm.neurobiol.2401212

Abstract

In this study, the researchers explore the effects of COVID-19-related challenges, such as fear and anxiety about COVID-19, the uncertainty of COVID-19, and the recognition of business opportunities for entrepreneurial intentions and business startups. This study used quantitative methods and based their findings on 278 usable samples collected from Egyptian entrepreneurs. Employing the Structural Equation Model (SEM) through SmartPLS4 shows that fear and anxiety arising from the COVID-19 pandemic harm entrepreneur [...]

1231 7192

Open Access Research Article

Biogeochemical Engineering: Technologies for Managing Environmental Risks

Received: 05 September 2022;  Published: 13 October 2022;  doi: 10.21926/aeer.2204040

Abstract

This research aims at one of the most important economic and environmental problems - the elimination of the consequences in case of emergency spills while cleaning petroleum products. The objectives of the study include the development and production of new biological products and biosorbents based on carbon-oxidizing microorganisms, testing the developed technologies for environmental risk management to eliminate the consequences of emergency petroleum product spills, creating an algorithm for conducting prelimin [...]

1267 7184

Open Access Review

Dynamic Resting-State Functional Connectivity in Migraineurs

Received: 19 July 2022;  Published: 26 October 2022;  doi: 10.21926/obm.neurobiol.2204143

Abstract

Functional magnetic resonance imaging (fMRI) is widely used to detect changes in the resting-state brain networks of migraine patients. Functional connectivity fMRI analysis examines the functional organization of the brain based on temporal correlations of blood oxygen level-dependent signal changes in different brain regions. Most previous resting-state fMRI studies have assumed that functional connectivity between brain regions remains relatively stable over time. However, it is now known that the brain is a com [...]

1200 7180

Open Access Review

A Systematic Literature Review on the Application of Explainable AI Approaches in the Assessment of Autism Spectrum Disorder

Received: 16 January 2025;  Published: 15 August 2025;  doi: 10.21926/obm.neurobiol.2503298

Abstract

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder associated with significant heterogeneity in symptoms and comorbid conditions. Studies have shown the value of early and accurate diagnosis in mitigating the associated social and behavioral challenges. Recently, studies have demonstrated the potential of machine learning (ML) models in identifying ASD patterns from neuroimaging, genetic, and behavioral data. However, the limited interpretability of these models poses a barrier to their clinical adopti [...]

891 7177

Open Access Original Research

Effect of Convective Mixing Process on Storage of CO2 in Saline Aquifers with Layered Permeability

Received: 19 October 2020;  Published: 25 February 2021;  doi: 10.21926/acr.2101012

Abstract

Convective mixing of free-phase CO2 and brine in saline aquifers is an established technique to accelerate the CO2 dissolution process. Correct estimation of the convection onset time and rate of CO2 dissolution into brine are two crucial parameters regarding safety issues, as the timescale for dissolution corresponds to the same time over which the free-phase CO2 has a chance to leak out from the storage site. In real practice, underground formations are heterogeneous with a layered structure, but the convective m [...]

1025 7176

Open Access Short Communication

Surgical Tips for Improving Success Rate of Deep Anterior Lamellar Keratoplasty in Keratoconus

Received: 20 April 2023;  Published: 15 June 2023;  doi: 10.21926/obm.transplant.2302188

Abstract

This article aims to provide some personal surgical tips to increase the success rate of deep anterior lamellar keratoplasty (DALK), a very advantageous yet complex procedure for treating keratoconus. The most troublesome surgical step is obtaining a successful pneumatic dissection of the deep stromal tissue, allowing the exposure of a deep cleavage plane. The following tips may aid the trainee surgeon in mastering this step, among others: performing a deep trephination, using intraoperative anterior segment optica [...]

994 7171

Open Access Research Article

Biocompatibility and Surface Integrity of Zirconia Ceramics Treated by Laser-plasma Driven Shock-waves

Received: 10 April 2022;  Published: 22 November 2022;  doi: 10.21926/rpm.2204025

Abstract

This is a multi-disciplinary paper focused on the preliminary results of deploying laser shock treatment (LST) to ZrO2 ceramics. This work has significance in several industrial sectors for components that will benefit from strengthening. These components are, namely: dental implants; cutting and drawing tools; valves, bearings, pressure vessels, heat exchangers and high-performance scissors and knives, where modification of hard, brittle materials properties such as that of a ZrO2, can yield a performance boost. T [...]

1143 7167

Open Access Research Article

Risk Matrix of Hydrological Disasters Combining Rainfall Thresholds and Social-Environmental Criteria

Received: 30 September 2022;  Published: 07 February 2023;  doi: 10.21926/aeer.2301019

Abstract

This paper presents a procedure for risk assessment for hydrological disasters considering the threshold rainfall and environmental and social criteria. A case study was carried out to test its feasibility in the northern region of the State of São Paulo, Brazil. The advantage of this procedure is that it only uses data available on government institutions and websites. For this reason, other regions and countries can easily adapt the procedure to their reality. Initially, the hydrological disasters were obtained i [...]

1102 7165

Open Access Original Research

Mental Health of Teachers during the First Wave of COVID-19 in Daegu, Korea: Challenges in Reopening Schools

Received: 25 February 2024;  Published: 06 May 2024;  doi: 10.21926/obm.neurobiol.2402221

Abstract

This study conducted an in-depth analysis of the psychological states of teachers during the first outbreak of coronavirus disease 2019 (COVID-19) using data on school mental health projects related to COVID-19 in Daegu from May to June 2020. The participants comprised 811 (34.9%) male and 1,511 (65.1%) female teachers in 1,041 (44.8%) middle and 1,281 (55.2%) high schools. After schools reopened, the most common causes of unbearable stress were unusual experiences, fear of infection, and negative emotions. Moreove [...]

1104 7160

Open Access Original Research

Exploring Spousal Relationships Post-Stroke and the Association Between Relationship Congruence and Dysphagia-Related Caregiver Burden

Received: 11 August 2022;  Published: 07 November 2022;  doi: 10.21926/obm.geriatr.2204210

Abstract

Stroke survivors often receive spousal support for post-stroke impairments. The quality of spousal caregiving and couples’ wellbeing can suffer from post-stroke relationship changes and caregiver burden. Because swallowing impairment (dysphagia) is common post-stroke and spouses providing dysphagia care may experience burden, it is also important to explore whether relationship changes post-stroke are associated with dysphagia outcomes. The purpose of this study was to describe stroke survivor-spouse relationships [...]

1339 7157

Open Access Original Research

Removal of As(III) from Water by Cellulase Templated TiO2: A Photocatalytic Oxidation Conjugated Adsorption Process

Received: 16 July 2022;  Published: 09 September 2022;  doi: 10.21926/cr.2203025

Abstract

TiO2 photocatalyst was prepared using cellulase as a biotemplate through a hydrothermal process. The as-prepared catalyst was characterized based on physicochemical techniques and was used to remove As(III) from contaminated water. The cellulase templated TiO2 photocatalyst (TiO2-cellulase) had a large specific surface area, which reached 166.6 m2·g–1. It also had a strong oxidation ability and, thus, behaved well in both photocatalytic oxidation of As(III) and dark adsorption. The pH of the solution h [...]

1218 7151

Open Access Original Research

Association of Stress with Healthy Aging, the Role of Physical Activity

Received: 14 October 2022;  Published: 29 December 2022;  doi: 10.21926/obm.geriatr.2204219

Abstract

The World Health Organization attracted more attention to the positive effects of physical activity (PA) and the adverse effects of stress on the health of older people and, therefore, attracted a more significant number of practitioners. To verify the impact of PA on stress in older people. Observational and analytical research, composed of 690 older people of both genders residing in Brazil, present in street races (as participants or observers), who volunteered to respond to the research protocol consisting of s [...]

1207 7150

Open Access Review

Locked Plating Versus Retrograde Intramedullary Nailing in The Surgical Fixation of Periprosthetic Supra-condylar Knee Fractures: An Updated Systematic and Meta-Analysis Review

Received: 25 November 2024;  Published: 02 June 2025;  doi: 10.21926/obm.geriatr.2502315

Abstract

Meta-analysist to evaluate impact of Surgical Methods on Outcomes in periprosthetic supracondylar knee fracture management. This study examines the rate of functional outcomes and complications associated with two distinct surgical methods for the management of periprosthetic supracondylar knee fractures in patients treated with Low Contact Locking Plates (LCP) and Retrograde Intramedullary Nails (RIMN). With the growing prevalence of total knee replacements, the incidence of periprosthetic supracondylar knee fract [...]

910 7148

Open Access Original Research

Mechanical Characterization of a Tunable 3-D Collagen-Hyaluronic Acid Hydrogel for Use in Cell Culture

Received: 28 June 2024;  Published: 17 December 2024;  doi: 10.21926/rpm.2404028

Abstract

Many cells demonstrate variances in behavior due to their cell culture environment. To provide a mechanically-tunable, tissue-like environment, a 3D hydrogel for cell culture was formulated using collagen (Col) and hyaluronic acid (HA) to help provide a system for studying these dynamic cellular responses in a soft-tissue environment. A design of experiments was organized to study the effects of collagen concentration, HA fragment size, and Col: HA mass ratio on the hydrogel mechanical properties. Mechanical charac [...]

1224 7145

Open Access Original Research

Differences in Blame-Like and Forgiveness-Like Judgments between Young People, Healthy Older People, and Older People with Dementia

Received: 19 October 2022;  Published: 03 April 2023;  doi: 10.21926/obm.geriatr.2302231

Abstract

The objective of the present experimental study was to compare how young people, healthy older people, and older people with dementia cognitively integrated three factors (Intention, Consequence, and Apology) when making blame-like judgments (prosecution and revenge) and forgiveness-like judgments (resentment and reconciliation). Thirty-four young people (Mage = 22.12, SD = 3.44), 22 healthy older people (Mage = 71.82, SD = 8.69), and 18 older people with dementia (Mage = 75, SD = 10.06) participated in the study. [...]

1373 7141

Open Access Original Research

A Probiotic Mixture Decreases Neuropathy and Oxidative Stress Markers in Diabetic Rats

Received: 11 May 2024;  Published: 30 September 2024;  doi: 10.21926/obm.neurobiol.2403247

Abstract

Diabetic neuropathy (DN) is a type of nerve damage caused by long-term hyperglycemia in diabetes mellitus (DM). The gut microbiota alters in DM. Therefore, improvement of the gut flora may affect neuropathic pain and oxidative biomarkers' responsiveness to the probiotic treatment. The present study aimed to assess the effects of probiotic supplementation on neuropathic pain and oxidative stress biomarkers in diabetic rats’ serum. Forty-eight rats (200-250 g) were randomly divided into four groups (n = 12 [...]

812 7137

Open Access Original Research

Modeling of Autonomous Microgrid Operated at Medium-Voltage Level and at Constant Frequency and Study of Its Voltage Profile

Received: 06 December 2022;  Published: 17 February 2023;  doi: 10.21926/jept.2301009

Abstract

To increase power level in an autonomous microgrid, higher voltage is necessary. In this paper, detailed Matlab/Simulink modeling of a microgrid operated at medium-voltage level and at constant frequency has been conducted. Modified boost converter and medium-frequency transformer isolated DC/DC converter are adopted for both solar energy and wind energy harnessing in order for them to be connected with the microgrid. This paper further adopted a differential evolution (DE)-based method to carry out load flow analy [...]

1155 7123

Open Access Research Article

Relationship between Hearing Loss Risk Factors and Hearing Screening Results in Newborns: A Retrospective Cross-Sectional Study

Received: 02 January 2023;  Published: 29 June 2023;  doi: 10.21926/obm.genet.2302184

Abstract

Congenital hearing loss can have a long-term impact on children’s speech and communication abilities. Early detection and intervention of hearing loss are important in newborns. It is well known that there are several risk factors for hearing loss; however, the relationship between these risk factors and hearing screening tests remains uncertain in Iran. Therefore, this study aimed to explore the relationship between hearing loss risk factors and Automated Auditory Brainstem Response (AABR) and Transient-Evok [...]

1166 7119

Open Access Original Research

Possible Preventive Effect of Ziziphora clinopodioides Lam. Essential Oil on Some Neurodegenerative Disorders

Received: 10 June 2022;  Published: 08 October 2022;  doi: 10.21926/obm.neurobiol.2204140

Abstract

The present article describes some characteristics of the effect of essential oil (EO) extracted from Ziziphora clinopodioides harvested from Armenian highlands on microglial cell lines (BV-2 wild-type (WT) and acyl-CoA oxidase1 (ACOX1)-deficient (Acox1–/–) cells). The mutant cell line was used as a model to investigate cellular oxidative damage following EO treatment. The main components of the tested EO were pulegone, isomenthone, 1,8-cineole, piperitone, and neomenthole, with concentrations of 42.1%, [...]

1136 7117

Open Access Review

Biochemical Foundations of Emotion Regulation: Implications for Pharmacological and Psychological Interventions-A Narrative Review

Received: 02 May 2025;  Published: 19 November 2025;  doi: 10.21926/obm.neurobiol.2504310

Abstract

Emotion regulation (ER) involves processes by which individuals modulate the intensity, duration, and expression of emotional responses, and its dysregulation is associated with a broad spectrum of psychological disorders. While traditionally conceptualized within psychological frameworks, ER is increasingly recognized as biologically grounded, involving intricate interactions between neurochemical, hormonal, and metabolic systems. This narrative review aims to synthesize current evidence on biochemical substrates [...]

1684 7117

Open Access Research Article

Arginine and Histidine-modified Layered Double Hydroxides Facilitate Transgene Expression in Cancer Cells in Vitro

Received: 14 June 2023;  Published: 21 September 2023;  doi: 10.21926/obm.genet.2303193

Abstract

Layered double hydroxides (LDHs) have interesting properties and structures that enable them to carry nucleic acids, such as deoxyribonucleic acid (DNA). This study synthesized LDHs using the co-precipitation method and functionalized with the amino acids arginine (Arg) and histidine (His) to promote proton-sponge activity for enhanced transgene expression. The LDHs were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), and nanoparticle tracking analysis (NTA). The interaction of [...]

1473 7112

Open Access Original Research

Incentivizing Alternative Fuel Vehicle Transactions: Analysis of Cash-for-Clunkers Transactions for New Alternative Fuel Vehicles

Received: 14 January 2022;  Published: 02 August 2022;  doi: 10.21926/jept.2203026

Abstract

Monetary incentives to accelerate the transition of private vehicle fleets to zero emissions promote sustainability in the transportation sector. Clean Cars for America to incentivize transactions for new battery power vehicles is a program in furtherance of sustainable transportation goals in the United States. Unfortunately, data on transactions for new alternative fuel vehicles (AFVs) are scarce so empirical research to explore the costs and/or the benefits of such programs is also scarce. Analysis of transactio [...]

1182 7112

Open Access Short Communication

Migraine in Adolescents: Comparison of Attack Frequency During School and Vacation Periods

Received: 18 May 2022;  Published: 16 August 2022;  doi: 10.21926/obm.neurobiol.2203131

Abstract

This citizen science project CLUE compared the attack frequency between school and vacation periods among adolescents. The data collection process adopted in citizen science projects opens up the possibility of conducting analyses by including a large number of participants over a long period and across different regions. The data on 684 migraine attacks reported by 68 adolescents aged 16 to 19 years were collected using an online platform and smartphone apps. A Fisher’s exact test was used to compare the distribut [...]

1158 7112

Open Access Review

Platelet Function in Experimental Models of Liver Cirrhosis

Received: 15 May 2019;  Published: 01 November 2019;  doi: 10.21926/obm.hg.1904039

Abstract

(1) Background: Platelet function is commonly altered in liver cirrhosis. In experimenta models of liver cirrhosis we have analyzed the mechanisms of this defective function. (2) Methods: Experiments were performed in a model of liver cirrhosis by bile duct-ligation in washed platelets by means of fluorescence spectroscopy with fura-2. (3) Results: We have found several alterations compatible with the existence of a hyperaggregatory state. These alterations are related to a defective platelet calcium handling, spec [...]

1446 7111

Open Access Research Article

Spin Entanglement – A Unifying Principle for Superconductors and Molecular Bonding

Received: 20 December 2023;  Published: 03 June 2024;  doi: 10.21926/rpm.2402012

Abstract

The spin-statistics theorem is generalized to include quantum entanglement. Specifically, within the context of spin entanglement, we prove that isotropically spin-correlated (ISC) states must occur in pairs. This pairing process can be composed of parallel or anti-parallel states. Consequently, the article proposes using ISC states as a unifying principle to explain better Bose-Einstein condensates, the theory of superconductivity, and molecular and atomic orbitals, all of which involve a pairing process. The theo [...]

923 7111

Open Access Original Research

Young Adult’s Mental Health Literacy in Relation to Depression and Their Attitudes Towards Complementary Medicine Practice

Received: 11 July 2022;  Published: 09 October 2022;  doi: 10.21926/obm.icm.2204047

Abstract

Depression and mental health-related issues are increasingly prevalent in young adolescents and adults and so is the use of Complementary Therapies (CTs) to treat depression. Systematic reviews have found that, of all CTs, acupuncture, exercise, and the herbal remedy St John’s Wort have the greatest amount of evidence for efficacy in treating depression. We aimed to assess Mental Health Literacy (MHL) levels in the treatment of depression and Complementary Therapy’s (CT) usage in adolescents and adults. Surveys wer [...]

1276 7109

Open Access Case Report

Therapeutic Use of Auto-Induced Cognitive Trance in a Chronic Pain Setting: A Case Study Using Mixed Methodology

Received: 14 August 2024;  Published: 05 March 2025;  doi: 10.21926/obm.icm.2501012

Abstract

Auto-induced cognitive trance (AICT) is a method for voluntarily entering modified state of consciousness. The therapeutic implications of AICT are still unknown. Since complementary approaches based on modified states of consciousness are recognized to be beneficial for patients suffering from chronic pain (e.g., hypnosis, meditation), we here present the first case report of a 68-year-old man with a long history of chronic pain linked to an open Spina Bifida L4-L5, who used AICT to improve his health condition. S [...]

1207 7094

Open Access Review

Therapeutic Exercise Holds the Key to Improve Hand and Upper Limbs Dystonia Rehabilitation Programs: A Systematic Review

Received: 20 September 2024;  Published: 27 February 2025;  doi: 10.21926/obm.neurobiol.2501272

Abstract

Upper limb dystonia is a focal locomotion disorder affecting arm, forearm, and hand muscles, causing abnormal movements given by repeated, steady, and intercontinuous contractions. There are different types of dystonia and the multifaced nature of this pathology is challenging in the treatment management, leading to a worsening of affected patients’ life quality, mainly from a psychological point of view, but also from a functional perspective. This work examines the present literature regarding upper limb dystonia [...]

917 7089

Open Access Original Research

Comparison of Sputum and Oropharyngeal Microbiome Compositions in Patients with Non-Small Cell Lung Cancer

Received: 01 August 2022;  Published: 07 November 2022;  doi: 10.21926/obm.genet.2204169

Abstract

Recent findings indicate that the microbiota is involved in the development of lung cancer by inducing inflammatory responses and generating genome damage. This study aimed to compare sputum microbiomes from the mouth and oropharynx in non-small cell lung carcinoma (NSCLC) patients. A second goal was to search for bacterial taxonomic units that behave differently in the microbiome of NSCLC patients and healthy subjects. In the study, the taxonomic composition of the sputum and oropharyngeal microbiomes of 23 male p [...]

1190 7088

Open Access Original Research

Interactive and Deep Learning-Powered EEG-BCI for Wrist Rehabilitation: A Game-based Prototype Study

Received: 14 August 2025;  Published: 24 September 2025;  doi: 10.21926/obm.neurobiol.2503302

Abstract

Motor deficits induced by neurological disorders impose a severe impact on activities of daily life. Conventional rehabilitation practices necessitate ongoing clinical supervision, which is costly and inaccessible. EEG-based brain-computer interface (BCI) systems offer a viable solution by facilitating neurorehabilitation through the direct interpretation of brain signals. Nonetheless, current systems are confronted with issues of real-time control, portability, and classification precision. The paper describes a n [...]

1290 7088

Open Access Research Article

Photodegradation of Polyethersulfone (PES), Polyvinylidene Fluoride (PVDF) and Polymethyl Methacrylate (PMMA) Microplastics via a Metal Organic Framework Namely ZIF-8/ZnO/C

Received: 27 August 2024;  Published: 17 October 2024;  doi: 10.21926/aeer.2404019

Abstract

The aim of this study was to photodegrade the Polyethersulfone (PES), Polyvinylidene fluoride (PVDF) and Polymethyl methacrylate (PMMA) microplastics using Zeolitic imidazolate framework-8/Zinc oxide/Carbon (ZIF-8/ZnO/C) nanocomposite generated under laboratory conditions. The produced nanocomposite was analysed using X-Ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Photo Spectroscopy (XPS), Scanning Electron Microscope (SEM), Diffuse reflectance UV-vis spectra (DRS) and Electron Spin R [...]

1312 7084

Open Access Original Research

COVID-19’s Psychological Threats and Future Career Anxiety among University Students

Received: 17 May 2024;  Published: 30 July 2024;  doi: 10.21926/obm.neurobiol.2403234

Abstract

The COVID-19 pandemic brought different intolerable and uncomfortable situations that ruined the students' academic performance, career opportunities, and social lives through depression, anxiety, fear, uncertainty, and mental illness. In this study, we examined the psychological threats of the COVID-19 among Egypt’s public-sector university students. We employed quantitative methods in this study and used a questionnaire to collect cross-sectional data. The Structural Equation Modeling (SEM) results show that Fear [...]

821 7080

Open Access Review

The Impact of Vitamin D on Type 2 Diabetes Mellitus: Exploring Its Role in Glucose Metabolism and Insulin Sensitivity

Received: 15 May 2025;  Published: 29 September 2025;  doi: 10.21926/rpn.2503021

Abstract

Vitamin D, a fat-soluble secosteroid, plays a pivotal role beyond its functions in calcium and bone homeostasis. Emerging evidence suggests its involvement in glucose metabolism and insulin sensitivity, thus influencing the pathophysiology of Type 2 Diabetes Mellitus (T2DM). For the current review, a search was conducted across four major databases: PubMed, Embase, Google Scholar, and Web of Science. The aim was to identify relevant studies and clinical trials, published in English, reporting the mechanistic insigh [...]

1227 7072

Open Access Original Research

Impact of COVID-19 on Chile's Energy Transition Policies and Goals

Received: 16 June 2022;  Published: 13 October 2022;  doi: 10.21926/aeer.2204041

Abstract

Because of climate change, greenhouse gas (GHG) emissions have increased, leading to the implementation of energy transition policies. Countries have adopted the Paris Agreement to curb the effects of climate change. The emergence of COVID-19 in 2020 led to the application of different measures to stop its transmission. This study evaluated the effects of COVID-19-related restrictions (such as quarantine and mobility restriction) in Chile during the first wave on compliance with the country's energy transition poli [...]

1208 7071

Open Access Original Research

Looking Beyond the Mother: Investigating Relationship Characteristics and Postpartum Depression Risk Factors

Received: 11 November 2022;  Published: 29 January 2023;  doi: 10.21926/obm.icm.2301010

Abstract

Postpartum depression (PPD) affects a notable number of women. While many of the risk and protective factors for PPD are specific to the mother, there are also factors that are related to the partner. However, the partner is often overlooked when assessing the landscape of PPD and potential treatment programs. This study sought to expand the knowledge on partner perceptions during the perinatal period. This online, cross-sectional survey of fathers who were in relationships with mothers who had given birth within t [...]

1117 7058

Open Access Editorial

Highlights of Complementary and Alternative Medicine in Nervous System Conditions: An Interview with Dr. James David Adams, Jr.

Received: 24 May 2019;  Published: 24 May 2019;  doi: 10.21926/obm.icm.1902032

Abstract

Highlights of Complementary and Alternative Medicine in Nervous System Conditions: An Interview with Dr. James David Adams, Jr.

1199 7053

Open Access Original Research

YNCRG Alleviated Hepatic Steatosis in Metabolic Syndrome Model Rats by Improving Lipid Metabolism and Chronic Inflammatory Reaction

Received: 25 October 2021;  Published: 30 June 2022;  doi: 10.21926/obm.icm.2202023

Abstract

YNCRG is a combination of five traditional Chinese ingredients with medicinal properties. We studied its effects and mechanism of action on a rat model of non-alcoholic fatty liver with metabolic syndrome. Eight-week-old male SHRcp rat(s) and Wister Kyoto (WKY) rats were adaptively fed for one week, after which they were randomly divided into three groups, including the control group (n = 9), the YNCRG group (n = 8), and the WKY group (n = 8). The WKY group could freely consume water, the control group was provided [...]

1015 7033

Open Access Review

Chemical Neuroscience of Heterocyclic N-Amines: Implications for Pain Management, Mental Health, and Opioid Withdrawal

Received: 05 December 2024;  Published: 10 June 2025;  doi: 10.21926/obm.neurobiol.2502289

Abstract

This study reviews the biochemical mechanisms and clinical implications of N-heterocyclic amine drugs, particularly in the context of pain management, mental health, and opioid withdrawal. It highlights the structural diversity and receptor binding capabilities of these compounds, which enable them to target the nervous system and cross the blood-brain barrier effectively. The article discusses the role of opioids in pain relief, detailing their agonistic effects on opioid receptors and the subsequent risk of addic [...]

1171 7027

Open Access Original Research

4Active Intervention for Promoting Physical Activity and Cognitive Flexibility Among Older Adults

Received: 03 July 2022;  Published: 26 December 2022;  doi: 10.21926/obm.geriatr.2204218

Abstract

Physical activity is essential to delaying cognitive decline and preventing cognitive impairment in older adults. We designed and implemented two-level 4Active intervention for older adults living in retirement communities. This study aimed to examine the effectiveness of the 4Active intervention in increasing physical activity and cognitive function in older adults. Fifty-eight eligible older adults with a mean age of 83.83 years (76.3% females) living in two retirement communities voluntarily participated in this [...]

1104 7024

Open Access Review

A Review of the Effects of Anthropogenic Activities during the Pandemic Lockdown Period Timeline on Water Quality

Received: 27 October 2022;  Published: 14 February 2023;  doi: 10.21926/aeer.2301020

Abstract

The pandemic has shown its effect on the world regarding health, economy, society, and environment. Whether it is a negative or positive impact, the period of this pandemic has a vast open platform for further studies. This review focused on the impact of the COVID-19 pandemic lockdown on water quality. It is hypothesized that due to the reduced amount of anthropogenic activity due to the global lockdown, the water quality of water resources increased and rejuvenated. This review showed the study period, methods an [...]

1148 7021

Open Access Original Research

The Remediation of Hexavalent Chromium Using Orange Peel Biosorbent from Industrial Effluents

Received: 28 February 2024;  Published: 09 February 2025;  doi: 10.21926/aeer.2501011

Abstract

One major cause of aquatic pollution is the accumulation of heavy metal ions. This study shows the biosorption properties of orange peel for removing chromium (CrVI) from industrial wastewater at a laboratory scale. This study focused on the biosorption of CrVI using orange peel biosorbent (OPB) from aqueous solutions in the plastic industry (PI), textile and fabrics industry (TFI), chemical industry (CI), and food industry (FI). The total Cr contents in effluents of FI, CI, TFI and PI varied between 30.0-38.0, 23. [...]

1085 7018

Open Access Editorial

Chess and Acupuncture?

Received: 18 April 2023;  Published: 19 April 2023;  doi: 10.21926/obm.icm.2302020

Abstract

This editorial briefly describes possible relationships and similarities between chess and acupuncture. Although the methods of chess and acupuncture could not be more different, possible joint effects on the brain can be hypothesized. However, the effectiveness of these joint effects has yet to be proven in scientific studies. Both chess and acupuncture can be used to improve physical and mental well-being. According to the author, the Yintang point could play a key role here.

1065 7018

Open Access Opinion

Vitamin D in Patients with Chronic Hepatitis C Virus Infection Receiving the Direct Antiviral Agents

Received: 23 February 2020;  Published: 30 March 2020;  doi: 10.21926/obm.hg.2001044

1508 7008

Open Access Original Research

Array Formation Testing with Multiple Azimuthal and Axial Pressure Transducers

Received: 12 April 2023;  Published: 27 November 2023;  doi: 10.21926/jept.2304038

Abstract

An early formation tester operating a “sink probe” that extracts fluids from the borehole, also measures pressures at its location; pressures are additionally collected at two passive sensors, one situated 180 deg away and the second about meter axially. These positions are not conducive to accurate permeability predictions, since pressure transient signals used for inverse analysis attenuate very rapidly. Closer probe spacings offer formation evaluation advantages at low mobilities because Darcy pressure dissipati [...]

1313 7008

Open Access Original Research

Shifting Pancreas Transplantation Rates and Demographics are the Culmination of Many Strategic Policy Changes

Received: 06 September 2022;  Published: 21 November 2022;  doi: 10.21926/obm.transplant.2204170

Abstract

The 2014 Pancreas Allocation System established national qualifying criteria for simultaneous kidney pancreas (SPK) transplantation. The 2019 UNOS Pancreas Transplantation Committee Policy 11.3.B modified these guidelines to expand transplantation. Subsequent effects on recipient demographics have not been studied. We analyzed 81 SPK transplantations performed at our center from June 2014 to December 2020 to compare recipient demographics and outcomes before and after the 11.3.B policy change. National data were al [...]

1085 7008

Open Access Review

The Impact of Wellbeing Interventions on the Anxiety Levels of Children Attending Low-Income Schools: A Systematic Literature Review

Received: 02 November 2023;  Published: 11 May 2024;  doi: 10.21926/obm.icm.2402026

Abstract

This systematic review examined the impact of wellbeing interventions on the anxiety levels of children attending low-income schools. Studies, published between January 2000 and April 2022, were included if they had samples of school aged children attending low-income schools who were given a universal school-based wellbeing intervention. Ten databases were searched systematically to identify 542 records. After title and abstract screening, 43 records remained for full text screening, and of these studies, 10 met i [...]

1381 7007

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