by Renata Martins Pacheco

Received: 09 September 2022;  Published: 15 December 2022;  doi: 10.21926/aeer.2204051

Climate change is one of the main challenges of the current century. Emissions taxes are one of the proposed ways to help in addressing this issue. In this sense, Portugal has introduced an Addition Tax on Carbon Emissions through Law N. 82-D/2014. One of the most notorious impacts of climate change in the country is the wildfires increasing in frequency and intensity. Forests provide various ecosystem services not valued by traditional markets, such as carbon sequestration. Recently, Portugal has created new envir [...]

by Wei Wang  , Sa Bi  , Huanhuan Li  and Tiesheng Li

Received: 21 September 2022;  Published: 02 December 2022;  doi: 10.21926/cr.2204042

Fabrication, arrangement, and controllable composition of ordered organometallic films are critical for designing a highly active catalyst and investigating the catalytic mechanism. In this paper, an organometallic terpyridine Pd(II)/Ni(II) monolayer linked on the silicon substrate surface (denoted as Si-Tpy-Pd1/Ni1) was prepared and characterized using water contact angle, ultraviolet spectra, X-ray diffraction, scanning electron microscopy, and X-ray photoelectron microscopy. Si-Tpy-Pd1/Ni1 exhibited high catalyt [...]

by Hidehiro Kamezaki  , Tatsuo Kanda  , Osamu Yokosuka  , Yasunori Kasahara  and Takayuki Sakurai

Received: 16 November 2016;  Published: 21 January 2017;  doi: 10.21926/obm.hg.1701001

(1) Background: Preventative treatment for Pneumocystis jirovecii pneumonia (PCP) has been recommended for patients receiving ≥20 mg/day prednisolone. We describe a patient who developed PCP while receiving a dose of 15 mg/day prednisolone, and consider criteria for the initiation of preventative therapy for PCP in patients with autoimmune hepatitis (AIH) treated with prednisolone. (2) Case Report: A 71-year-old woman initially possessed dark-colored urine, white stool, and decreased appetite, which indicated hepat [...]

by Vikas Dhikav  , Pankaj Kumar  and Praveen Kumar Anand

Received: 23 August 2022;  Published: 23 November 2022;  doi: 10.21926/obm.geriatr.2204214

Various grades of cognitive impairment generally occur in older adults over the age of 55, where cardiovascular risk factors such as diabetes and/or hypertension, coronary artery disease, or cerebrovascular accidents are also common. Cognitive impairment occurs in various forms, from mild or amnesia such as forgetting today's date to more ominous and progressive forms, such as frank dementia. Over 5 million people worldwide suffer from dementia, most of whom live in low- and middle-income countries. It has been env [...]

by Ellen Kuo  , Esther Belogolovsky  , Sarah Fracci  , Amy Wozniak  , Marina Feffer  , Rachel Klauber  , Theodote K. Pontikes  and Edwin Meresh

Received: 03 October 2022;  Published: 02 March 2023;  doi: 10.21926/obm.neurobiol.2301159

The Coronavirus Disease (COVID-19) pandemic has contributed to a co-occurring psychiatric epidemic. Children and adolescents have been particularly impacted, with disruptions in continuity of learning and healthcare. Psychological stressors such as fear of infection, boredom, decreased socialization, supply shortages, and incomplete information have contributed to low mood, irritability, insomnia, and emotional exhaustion. Our study contributes to this research by quantifying the devastating psychiatric toll that t [...]

by Beom-Jin Lee  , Manal Hadi Ghaffoori Kanaan  , Sura Saad Abdullah  and Abdolmajid Ghasemian

Received: 04 July 2025;  Published: 18 August 2025;  doi: 10.21926/obm.genet.2503308

Cancer continues to be one of the leading causes of global death, and conventional therapies have limited efficacy because of their toxicity, drug resistance, and off-target effects. Plant-derived nanoparticles (PDNPs) have emerged as suitable alternatives as they have biocompatibility, biodegradability, and multifunctional therapy. In this review, we discussed the recent advancements in PDNPs for cancer therapy, including the green synthesis of PDNPs using phytochemical (flavonoids, terpenoids) reducing and cappin [...]

by S.Amitha Banu  and Khan Sharun

Received: 25 May 2023;  Published: 02 June 2023;  doi: 10.21926/obm.transplant.2302187

Platelet-rich plasma (PRP) is a promising tool in regenerative medicine because it stimulates tissue repair and regeneration. PRP contains a high concentration of platelets, growth factors, and cytokines involved in the healing process. This editorial paper aims to give an overview of PRP in regenerative medicine and its potential applications in various medical fields such as orthopedics, dentistry, dermatology, and wound healing. PRP can be integrated with other regenerative therapies, such as stem cell and gene [...]

by Oreste Piccolo  , Elisabetta Parodi  and Antonella Petri

Received: 14 September 2022;  Published: 17 November 2022;  doi: 10.21926/cr.2204041

In this study, a PoC (Proof of Concept) of a possible biomass valorization of flax and camelina oilseed press cakes was presented. Biocatalyzed hydrolysis of residual oils and proteins extracted from these wastes was studied. The biotransformation of oils was performed using commercial immobilized lipases, including Amano PS, Amano AK, and Candida Antarctica Lipase B (CALB). Acylglycerols were partially or fully hydrolyzed using Amano PS and AK. Triglycerides were not hydrolyzed by CALB, which behaved differently. [...]

by Mahmoud F. Elmorshedy  , Abualkasim Bakeer  and Dhafer Almakhles

Received: 14 February 2023;  Published: 09 May 2023;  doi: 10.21926/jept.2302017

The special design of linear induction machines (LIMs) leads to adverse effects caused by the longitudinal and end effects. These effects make the thrust control of the LIMs most attractive because its value decreases sharply with the speed increase. Thus, finite-state model predictive control (FS-MPC) is developed to increase the performance of the LIMs. However, the variable switching frequency is the main drawback of this control. Consequently, the main objectives of this paper are to propose FS-MPC with a const [...]

by Amjad Mizyed

Received: 23 December 2024;  Published: 21 April 2025;  doi: 10.21926/jept.2502007

Water scarcity is one of the most pressing global challenges, particularly in arid and semi-arid regions. In this context, the Gaza Strip, where groundwater is the only available natural water resource, faces severe water stress due to overexploitation and drought conditions. This study aimed to review the recent water budget for the Gaza Strip by collecting data for the years (2021-2022) which was analyzed, discussed, and compared with other studies. The results showed a sharp deterioration in the Gaza Strip in te [...]

by Isadora Muller de Oliveira  , Letícia Caroline de Oliveira Vital  , Izabela de Siqueira Reis Regueira  and Marcos Paulo Gomes Mol

Received: 02 July 2025;  Published: 11 November 2025;  doi: 10.21926/aeer.2504031

The management of healthcare waste (HCW) presents a significant environmental and public health challenge, aggravated by gaps in current Brazilian federal regulations. This study provides a comprehensive analysis of specific state and municipal legislation on HCW, comparing it with ANVISA Resolution No. 222/2018 and CONAMA Resolution No. 358/2005 to ascertain whether local regulations enhance management practices and can act as supplementary instruments to federal guidelines. The methodology was structured into thr [...]

by Rene J. Duquesnoy

Received: 11 July 2018;  Published: 05 September 2018;  doi: 10.21926/obm.transplant.1803018

The Holy Grail to Clinical Transplant Tolerance is Paved with HLA Epitopes

by Sofia Oliveira Correia  , Catarina Eusébio  , Ana Sofia Cipriano  , Virginia Lopes  , José Ramón Vizcaíno  , António Cabrita  , Manuela Almeida  , Sofia Pedroso  , Leonidio Dias  , La Salete Martins  and António Castro Henriques

Received: 18 October 2018;  Published: 07 March 2019;  doi: 10.21926/obm.transplant.1901057

Mucormycosis is an angioinvasive and potentially fatal fungal infection caused by ubiquitous filamentous fungi. Cutaneous mucormycosis is an emerging infection and potentially lethal. Our aim was to review the literature on cutaneous mucormycosis. We present a case of a renal transplant patient with a surgical wound infection 20 days after kidney transplant. This case is an example on how early diagnosis is crucial and, since culture is less sensitive, microscopic evaluation of the characteristic broad hyphae is th [...]

by Carsten Croonenbroeck  and David Hennecke

Received: 06 February 2024;  Published: 15 March 2024;  doi: 10.21926/jept.2401008

We address the Wind Farm Layout Optimization (WFLO) problem and tackle the optimal placement of several turbines within a specific (wind farm) area by incorporating additional aspects of an economically driven target function. With this, we contribute three refinements for WFLO research: First, while many research contributions optimize the turbines' locations subject to maximum energy production or energy efficiency, we instead pursue a strategy of maximizing a profit objective. This enables us to incorporate inne [...]

by Roberto Anaya-Prado  , Ana P. Cárdenas-Fregoso  , Ana M. Reyes-Perez  , Danielle M. Ortiz-Hernandez  , Montserrat Quijano-Ortiz  , Monica V. Delgado-Martinez  , Ana S. Pelayo-Romo  , Roberto Anaya-Fernández  , Michelle M. Anaya-Fernández  , Consuelo C. Azcona-Ramirez  , Ivan F. Garcia-Ramirez  , Miguel A. Guerrero-Palomera  , Daniel Gonzalez-Martinez  , Citlalli S. Guerrero-Palomera  , Karina Paredes-Paredes  and Claudia Garcia-Perez

Received: 23 February 2024;  Published: 16 July 2024;  doi: 10.21926/obm.neurobiol.2403232

The human gastrointestinal (GI) tract harbors many microorganisms, including viruses, protozoa, archaea, fungi, and bacteria. Altogether, these microbes constitute what we know as the gut microbiome (GM). These commensal communities have important implications for human health. They influence physiological processes through different mechanisms, including synthesizing neurotransmitters, regulating enzymatic pathways, and releasing molecules responsible for different signal pathways. The interaction between GM and b [...]

by Priya R. Bhosale  , Oliver H. Wang  and Jeannelyn S. Estrella

Received: 08 July 2019;  Published: 28 October 2019;  doi: 10.21926/obm.hg.1904038

Background: Pure pancreatic-type ACC outside the pancreas is extremely rare. Methods: We presented a very rare case of primary ACC of the pancreatic-type involving jejunum with a synchronous metastasis to left adrenal gland arising in well-developed ectopic pancreas which had fully developed pancreatic acini, islets of Langerhans, ductal structures, pancreatic cancer precursor lesions and a well-formed minor papilla that opens to the mucosal surface of jejunum. We also reviewed all 21 cases of pure pancreatic-type [...]

by Ya Wen

Received: 28 November 2017;  Published: 05 December 2017;  doi: 10.21926/obm.neurobiol.1704007

More and more studies revealed links amongst neurological disorders, heart diseases and cancers. For example, people with subclinical cardiovascular diseases are at higher risk for Alzheimer's disease, Parkinson’s disease is associated with varied risk of cancer, Autism Spectrum Disorders and cancer have overlapping genes and molecular pathways, heart disease and cancer share common risk factors, etc. It is intriguing how are these conditions that appear to be completely different linked together.

by Ginevra G Adamo  , Sergio D'Angelo  , Angeli Christy Yu  , Marco Pellegrini  , Federico Bernabei  , Vincenzo Scorcia  and Giuseppe Giannaccare

Received: 17 June 2022;  Published: 02 August 2022;  doi: 10.21926/obm.transplant.2203164

Graft-versus-host disease (GVHD) is a serious complication that may occur in patients receiving allogeneic hematopoietic stem cell transplant (HSCT). GVHD occurs because of the immunological reaction between the donor’s T cells and the recipient’s antigens; GVHD may develop in different tissues, including the eye. Corneal perforation is an uncommon but vision-threatening manifestation of GVHD. We reported the case of a 65-year-old male patient who developed corneal perforation sequentially in both eyes 3 years afte [...]

by Jacques De Reuck  , Florent Auger  , Nicolas Durieux  , Claude-Alain Maurage  , Vincent Deramecourt  , Charlotte Cordonnier  , Florence Pasquier  , Didier Leys  and Regis Bordet

Received: 24 September 2020;  Published: 10 December 2020;  doi: 10.21926/obm.geriatr.2004142

The influence of cerebral amyloid angiopathy (CAA) in Alzheimer’s disease (AD) remains unexplored. The present post-mortem study investigated possible differences in the degree of hippocampal atrophy (HA) between AD patients with and without CAA using 7.0-tesla magnetic resonance imaging (MRI). Also, the incidence of the hippocampal cortical micro-infarcts (HCoMIs) and hippocampal cortical micro-bleeds (HCoMBs) is compared to those in the neocortex. The examined post-mortem brains included 30 AD-CAA cases and 20 AD [...]

by OBM Genetics Editorial Office

Received: 09 January 2023;  Published: 10 January 2023;  doi: 10.21926/obm.genet.2301176

An Interview with Dr. Yuri Shavrukov

by Yashiro Rojas  , Evana Halaka  , Mary Hanna  , Alex Sidotu  , Jehan Joma  , Mina Mikhael  , Roger A. Lalancette  and Ivan Bernal

Received: 26 July 2020;  Published: 07 September 2020;  doi: 10.21926/acr.2003008

The compound, [cis-dichloro-(tris-2-amino(ethylamine))cobalt(III)]chloride hydrate, [cis-Cl2-(tren)Co(III)Cl]·H2O, a conglomerate crystallizing in P21 with Z = 4 (Z’ = 2), has been used as a precursor in the synthesis of a new dicobalt(III) peroxo complex: [(μ2-hydroxo)(μ2-peroxo)bis(tris-2-amino(ethylamine))di-cobalt(III)] tris(triiodide) dihydrate. This material crystallizes, without disorder, in space group P212121 with Z = 4 (Z’ = 2), thus making it, unambiguously, an example of a conglomerate. Its cell constan [...]

by Raymond H. Baillargeon  , Marylène Charette  , François Tessier  and Kevin P. Brand

Received: 08 March 2022;  Published: 03 August 2022;  doi: 10.21926/obm.icm.2203031

The current recommendations of the Canadian Paediatric Society about monitoring children’s disruptive behaviors at well-child visits call for screening if behavioral concerns are being raised by parents. But do parents’ concerns about their child’s behavior constitute a reliable means for primary care providers (PCPs) to decide either in favor or against screening? We conducted a rapid systematic review of the literature by identifying documents that cited the landmark study by Glascoe and her col [...]

by OBM Genetics Editorial Office

Received: 07 July 2022;  Published: 13 July 2022;  doi: 10.21926/obm.genet.2203160

by Filippo Lixi  , Benedetta Pintus  and Giuseppe Giannaccare

Received: 27 February 2024;  Published: 07 June 2024;  doi: 10.21926/obm.transplant.2402218

Calcareous corneal degeneration is a rare disease characterized by calcium phosphate deposition into the deep corneal layers. Corneal calcification has a multifactorial origin and is associated with various systemic and ocular conditions. Several treatment options showed promising results in the management of this disorder. Herein, two cases of calcareous degeneration occurring postoperatively in patients undergoing surgery for retinal detachment (case #1) and glaucoma (case #2) were reported. Despite normal serum [...]

by Michael D. Owens  and Megan Halliday

Received: 24 December 2020;  Published: 30 August 2021;  doi: 10.21926/obm.icm.2103025

The coronavirus (COVID-19) pandemic continues to bring challenges in identification and management of which the “happy hypoxic” or silent hypoxia presentation has been found to present its own unique challenge. A 67-year-old African American COVID-19 positive female presents to the emergency department (ED) with a chief complaint of decreased oral intake and responsiveness, oriented and stable, with oxygen saturations found to drop as low as 47%. The patient was successfully managed with supplemental oxygen and det [...]