by Hülya Çakmur

Received: 23 March 2023;  Published: 14 August 2023;  doi: 10.21926/obm.geriatr.2303245

The geriatric population is increasing all over the world. Aging people have special health requirements and comprehensive medical checkups prevent physical, functional and mental decline during the aging period. This study aimed to examine the fitness level and identify problems with the well-being of elderly persons. In this context, the study also attempted to determine the relationship between socio-demographic factors and the health status of elderly adults. In this cross-sectional study, 168 elderly adults (≥ [...]

by Mohammad Shabani  , Elham Hassanpour  , Fatemeh Aghighi  , Mojgan Mohammadifar  , Fereshteh Bahmani  and Sayyed Alireza Talaei

Received: 11 May 2024;  Published: 30 September 2024;  doi: 10.21926/obm.neurobiol.2403247

Diabetic neuropathy (DN) is a type of nerve damage caused by long-term hyperglycemia in diabetes mellitus (DM). The gut microbiota alters in DM. Therefore, improvement of the gut flora may affect neuropathic pain and oxidative biomarkers' responsiveness to the probiotic treatment. The present study aimed to assess the effects of probiotic supplementation on neuropathic pain and oxidative stress biomarkers in diabetic rats’ serum. Forty-eight rats (200-250 g) were randomly divided into four groups (n = 12 [...]

by Nanimpo Kansongue  , Stephen Vertigans  and James Njuguna

Received: 22 December 2024;  Published: 13 October 2025;  doi: 10.21926/jept.2504014

This work investigates the potential of renewable energy to significantly reduce Togo’s energy deficit, offering a critical analysis of the country’s current energy landscape. It evaluates the availability and viability of renewable energy sources—particularly solar and small-scale hydropower—and examines the mismatch between energy supply and growing demand. The study highlights Togo’s heavy reliance on biomass and energy imports from neighbouring countries such as Ghana, Côte d’Ivoire, and Nigeria, which exacerba [...]

by Lie Zhang  , Reza D. Fakhrabadi  , Maryam Khoshkhoo  and Husien Salama

Received: 29 December 2021;  Published: 09 October 2022;  doi: 10.21926/jept.2204031

Integrating large-scale wind energy in modern power systems necessitates high-efficiency mathematical models to address classical assumptions in power systems. In particular, two main assumptions for wind energy integration in power systems have not been adequately studied. First, nonlinear AC power flow equations have been linearized in most of the literature. Such simplifications can lead to inaccurate power flow calculations and result in technical issues. Second, wind power uncertainties are inevitable and have [...]

by Martina C Cornel

Received: 13 July 2017;  Published: 11 February 2018;  doi: 10.21926/obm.genet.1801013

Technology makes it possible to expand many of the current screening programs. Initiatives for preconception screening of carrier status of recessive diseases, prenatal screening of aneuploidies and neonatal screening were initially undertaken by targeting one or at most, a few, conditions. Tandem mass spectrometry and genomic technologies, such as sequencing and panel testing, make it possible to increase the scope of these programs to include more disorders or markers. While inclusion of a larger number of condit [...]

by Meir Djaldetti  , Chiya Moshe Leibovitch  and Hanna Bessler

Received: 28 June 2020;  Published: 19 November 2020;  doi: 10.21926/obm.hg.2004053

The current study aimed to investigate the effect of a multi-species probiotic (MSP) on cytokine production by human peripheral blood mononuclear cells (PBMCs) and their immune dialogue with HT-29 colon cancer cells. PBMCs were incubated with MSP and their effect on cell proliferation and TNFα, IL-1β, IL-2, IL-6, IFNγ, IL-10, and IL-1ra production was evaluated. The impact of MSP on the cytokine production by PBMC stimulated by HT-29 cells was detected. Not-stimulated PBMC incubated with MSP showed increased produc [...]

by Fausto Garmendia-Lorena

Received: 03 August 2022;  Published: 12 December 2022;  doi: 10.21926/obm.genet.2204173

This study aimed to reveal the evolution and characteristics of the COVID-19 pandemic in high-altitude areas of Perú. An observational, descriptive, retrospective and longitudinal study based on information from the Peruvian Ministry of Health, COVID-19 Situational Room, warning from the National Epidemiology Center, Prevention and Disease Control, and the Panamerican Health Organization (PAHO) was conducted to analyze the occurrence of the COVID-19 pandemic in Perú from the beginning of the pandemic until March 7, [...]

by Ana Valado  , Márcia Morais  , Stephanie Fortes  , Joana Rosado  , João Paulo Figueiredo  and Armando Caseiro

Received: 20 November 2023;  Published: 21 May 2024;  doi: 10.21926/obm.icm.2402028

Hydrotherapy is highly recommended for older adults because it offers warmth and support, so people with pain or reduced mobility and balance can move and exercise more freely compared to regular physical activity. The high plasma antioxidant capacity of uric acid in neutralizing oxidative species and the importance of nitric oxide (NO) in vasodilation and inflammatory response are relevant in older adults. This work aimed to evaluate hydrotherapy's effect on uric acid and NO concentrations in a population aged ≥ 6 [...]

by Hunter Heineman  , Omran Omar  , Benjamin Rippel  , Ryan Keeley  , Michael Mehan  , Surendra Gupta  and Gerald A. Takacs

Received: 21 August 2022;  Published: 06 December 2022;  doi: 10.21926/jept.2204040

Ozone was reacted with the aromatic membrane polyetheretherketone (PEEK) to form oxidized functional groups on the surface to enhance the attraction and transport of protons in fuel cells. Ozonation of unsaturated C-C sp2 bonds in PEEK formed a primary ozonide which dissociated to primarily produce O=C-O/O=C-OH moieties, and the root mean squared roughness factor (Rq) decreased from 7.4 nm, for the untreated sample, down to 3.1 nm. The oxidation of the surface and decrease in surface roughness made the surface incr [...]

by Talha Nazir  , Muhammad Umair  , Muhammad Mushhood Ur Rehman  , Reeda Saeed  , Osama O Zaidat  and Junaid S. Kalia

Received: 02 June 2023;  Published: 09 January 2024;  doi: 10.21926/obm.neurobiol.2401206

According to 2019 WHO data, neurological conditions contribute to 1503.39 disability-adjusted life years (DALYs) per 100,000 population. Approximately 57% of office-based physicians use EHR systems and the natural place to incorporate standardized ePRO is into EHR. However, implementing patient-reported outcomes (PROs) for neurological conditions is challenging because many patients are elderly, have comorbidities, and experience cognitive impairment. As healthcare digitization increases, we propose a framework for [...]

by Esra Pehlivan

Received: 11 December 2024;  Published: 03 March 2025;  doi: 10.21926/obm.transplant.2501239

Cystic fibrosis (CF) is a genetic disorder that significantly impacts respiratory function, leading to progressive lung damage and ultimately respiratory failure. Lung transplantation (LTx) is a critical intervention for CF patients with end-stage lung disease, offering improved survival and quality of life. Pulmonary rehabilitation (PR) plays a pivotal role both preoperatively and postoperatively in optimizing outcomes for LTx candidates and recipients. Pre-transplant PR interventions, including exercise programs, [...]

by Byron J. Hoogwerf

Received: 09 July 2024;  Published: 20 February 2025;  doi: 10.21926/obm.geriatr.2501299

Sarcopenia is more common in persons with type 2 diabetes mellitus (T2DM) than in persons without diabetes. There is overlap of some pathophysiologic features of sarcopenia and T2DM. In addition, the risk for sarcopenia is associated with common complications of T2DM including renal disease, cardiovascular disease and neuropathy. Glycemic control in T2DM may have some benefits on sarcopenia. The specific effects of glucose lowering agents on sarcopenia suggest that metformin, insulin, thiazolidinediones and GLP1 re [...]

by Tülin Avcı Hansu

Received: 25 December 2023;  Published: 15 May 2024;  doi: 10.21926/cr.2402005

In this study, by producing bifunctional material, hydrolysis, and supercapacitor applications were investigated. The carbon nanotube-supported Pt catalyst was prepared using the sodium borohydride (NaBH4) reduction. Surface characterization of the synthesized Pt/CNT catalyst was performed using scanning electron microscopy-energy dıstrıbutıon X-ray spectrometer (SEM-EDX), X-ray diffraction (XRD), and transmission electron microscopy (TEM). Hydrolysis experiments were performed after deciding on the appropriate ato [...]

by Jalal Uddin  , Meredith Greene  , Leslie Dubbin  , Madeline Deutsch  and Jason D. Flatt

Received: 28 July 2023;  Published: 15 December 2023;  doi: 10.21926/obm.geriatr.2304261

Housing is one of the top four most needed services for LGBTQ+ older adults, and this study focuses on the intersection of depression and social antecedents among LGBTQ+ older adults eligible for low-income housing. To explore social antecedents (i.e., demographics, early events, later events, social integration, and stressors) associated with screening positive for depression among low-income LGBTQ+ older adults from two cities in the Western United States. A cross-sectional study was conducted with LGBTQ+ older a [...]

by Walter Calderón-Gerstein  , Gabriela Torres-Samaniego  , Kevin Pazos-Sovero  , Mirella Calderón-Anyosa  , Merly Quisurco-Cárdenas  and Viviana Dorregaray-Lizárraga6

Received: 01 December 2022;  Published: 19 April 2023;  doi: 10.21926/obm.genet.2302180

This study aims to determine the relationship between the severity of lung tomographic compromise with arterial oxygenation and inflammatory markers in patients with COVID-19, and to evaluate the relationship between the CTSS tomographic severity score and the mortality risk in a high-altitude population. A retrospective, longitudinal study reviewed medical records between January and July of 2021 at the Daniel Alcides Carrión Regional Teaching Clinical Surgical Hospital in Huancayo. Categorical variables were anal [...]

by Donny Japly Pugesehan  , Vernando Yanry Lameky  and Agustinus Mathinus Luther Batlajery

Received: 12 June 2024;  Published: 21 August 2024;  doi: 10.21926/obm.genet.2403258

"Case Studies in the Ethics of Assisted Reproduction" explores the moral and ethical implications of assisted reproductive technologies (ART), such as in vitro fertilization (IVF), surrogacy, and genetic screening. These findings outline ethical dilemmas, including the importance of informed consent, and highlight a multidisciplinary approach involving law, bioethics, reproductive endocrinology, and reproductive biology. Using case studies, the findings address ethical challenges in ART practice, such as the transf [...]

by Aml Labib  , Jitesh Jeswani  and Durga AK Kanigicherla

Received: 26 June 2023;  Published: 13 October 2023;  doi: 10.21926/obm.transplant.2304199

IgAN is a major cause of end-stage kidney disease (ESKD) leading to kidney transplantation in a significant proportion of patients. However, its recurrence in transplanted kidneys can lead to graft loss. The rate of graft loss attributable to IgAN after transplantation is variably reported in different retrospective cohorts. Previous reports describe recurrence rates of 22-58% with a 1.3% to 16% rate of graft loss. Accurate diagnosis and prediction of graft loss are important for planning effective therapies to imp [...]

by Ayan Mishra  , Barsha Panda  and Debosree Ghosh

Received: 10 May 2023;  Published: 26 October 2023;  doi: 10.21926/obm.geriatr.2304255

Non Alcoholic Fatty Liver Disease (NAFDL) is a condition in which an individual suffers from an accumulation of fat in the liver. This is a disease condition with a multifactorial etiology. Some potent causes of such conditions are altered thyroid condition, abnormal metabolism in the body due to aging or menopause, or any other hormonal imbalance. Most of these causes are regulated by genetics, lifestyle, and environmental factors. Menopause comes with tremendous hormonal turmoil in the human body and brings vario [...]

by Matthew Kostek  and Siyu Liu

Received: 28 March 2023;  Published: 19 September 2023;  doi: 10.21926/obm.genet.2303192

Human skeletal muscle exhibits remarkable plasticity, being responsive to chemical, mechanical, metabolic, and inflammatory stress. When the homeostatic disturbance is below a threshold of significant damage, the muscle responds by modifying metabolic activity, cell size/shape, and structure, thereby normalizing cellular function. If the disturbance causes significant damage, skeletal muscle, along with a precisely choreographed response from the immune system, can regenerate. Very few pathological conditions inhib [...]

by Elvira A. Guseinova  and Samira R. Safarova

Received: 28 July 2022;  Published: 26 October 2022;  doi: 10.21926/cr.2204037

In this study, we found that adding catalytic cracking feedstock, vacuum gas oil, and naphthenic acids in the amount of 0.005–0.0075% vol. increased the liquid target fractions, i.e., gasoline and light gas oil. The decrease in the yield of hydrocarbon gas at a practically constant degree of conversion of the raw material indicated a small proportion of the reactions of re-cracking of the resulting products. This also indicated the resource-saving nature of the process, allowing a larger amount of gasoline fraction [...]

by OBM Transplantation Editorial Office

Received: 06 January 2022;  Published: 07 January 2022;  doi: 10.21926/obm.transplant.2201157

The editors of OBM Transplantation would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recogni [...]

by Paul O'Hara

Received: 20 December 2023;  Published: 03 June 2024;  doi: 10.21926/rpm.2402012

The spin-statistics theorem is generalized to include quantum entanglement. Specifically, within the context of spin entanglement, we prove that isotropically spin-correlated (ISC) states must occur in pairs. This pairing process can be composed of parallel or anti-parallel states. Consequently, the article proposes using ISC states as a unifying principle to explain better Bose-Einstein condensates, the theory of superconductivity, and molecular and atomic orbitals, all of which involve a pairing process. The theo [...]

by James S. Powers  , Shana Atkins  and Allison B. McCoy

Received: 05 June 2022;  Published: 28 September 2022;  doi: 10.21926/obm.geriatr.2203205

Many health systems have joined the Age-Friendly Health Systems movement to provide every older adult safe, high-quality care aligned with what matters most. Becoming an Age-Friendly Health System means that hospitals and health care systems reliably use a set of evidence-based practices known as the “4M’s” – What Matters, Medication, Mentation, and Mobility – to provide care for older, disabled and medically complex patients across all care settings. Implementing the Institute for Healthcare Improvement’s (IHI) 4M [...]

by Charles E. Carraher  , Michael R. Roner  , Jessica Frank  , Paul Slawek  , Francesca Mosca  , Kimberly Shahi  , Alisa Moric-Johnson  and Lindsey Miller

Received: 31 January 2019;  Published: 14 May 2019;  doi: 10.21926/obm.hg.1902019

Pancreatic cancer is the fourth leading cause of death in the USA. Treatment is seldom successful. A wide variety of organotin polymers exhibit good inhibition of human pancreatic cancer cell lines AsPC-1 and PANC-1. The AsPC-1 is an adenocarcinoma pancreatic cell line and PANC-1 which is an epithelioid carcinoma pancreatic cell line. Synthesis is rapid employing commercially available reactants and the interfacial polymerization that is employed in the commercial synthesis of aramids and polycarbonates.

by Kajsa Landgren  , Hólmfríður Margrét Bjarnadóttir  , Helga Sif Friðjónsdóttir  and Jóhanna Bernharðsdóttir

Received: 19 December 2024;  Published: 15 April 2025;  doi: 10.21926/obm.icm.2502018

Depression, insomnia, cravings, and anxiety are significant and often long-lasting health problems. As medication has limited effect and often side effects, complementary methods such as ear acupuncture are used in mental health care. To describe mental health care users' experiences of ear acupuncture, including ratings of sleep, anxiety, depression, stress, pain, and cravings. This mixed methods study included in- and outpatients at a mental health rehabilitation service in Iceland. Standardized ear acupuncture ( [...]