by Suhani Sharma  , Sonali Karhana  and Mohd. Ashif Khan

Received: 15 May 2025;  Published: 29 September 2025;  doi: 10.21926/rpn.2503021

Vitamin D, a fat-soluble secosteroid, plays a pivotal role beyond its functions in calcium and bone homeostasis. Emerging evidence suggests its involvement in glucose metabolism and insulin sensitivity, thus influencing the pathophysiology of Type 2 Diabetes Mellitus (T2DM). For the current review, a search was conducted across four major databases: PubMed, Embase, Google Scholar, and Web of Science. The aim was to identify relevant studies and clinical trials, published in English, reporting the mechanistic insigh [...]

by Wanda Liguigli  , Rita Cengarle  , Anita Rimanti  , Giovanna Catania  , Laura Faglioni  , Simone Voltolini  , Carla Rabbi  , Roberto Barbieri  , Ilenia Zanardi Di Pietro  , Beatrice Vivorio  , Patrizia Morselli  , Chiara Iridile  , Laura Rigotti  and Maurizio Cantore

Received: 26 October 2022;  Published: 27 March 2023;  doi: 10.21926/obm.geriatr.2301230

Comprehensive Geriatric Assessment (CGA) is utilized to plan social and health care of the elderly and to complete the diagnostic-therapeutic choice of oncologist also considering early integration with palliative care. Cancer patients (pts) hospitalized aged ≥70 years were screened by the G8 questionnaire to define if necessary CGA. CGA identified: fit, unfit and frail pts. We screened 95 pts by G8 and 93 (98%) were at risk. Pts at risk, evaluated by CGA resulted: 3 fit, 45 unfit and 45 frail. 3 fit pts received s [...]

by Nicole Mölders

Received: 11 August 2020;  Published: 17 August 2020;  doi: 10.21926/aeer.2003001

by Dipti Nikam  and Abbas S. Milani

Received: 05 May 2022;  Published: 24 April 2023;  doi: 10.21926/rpm.2302017

This study evaluates the influence of different loading angles and the area of loading on the ensuing stress distribution and the physical response of a natural central incisor tooth, using a 3D finite element analysis. The CAD model of the incisor tooth assembly (including enamel, dentin, periodontal ligament, pulp, gingiva and jaw bone) was subject to an external (chewing) load of 100 N, over four different areas and at four different angles along the vertical. It was observed that the tooth experiences high von- [...]

by Elga J. Vargas  , Julio C. Martinez  and Lina A. Gomez

Received: 26 April 2024;  Published: 03 October 2024;  doi: 10.21926/obm.transplant.2404225

Acne is a chronic inflammatory condition affecting the pilosebaceous units of the skin, characterized by the formation of papules, cysts, comedones, pustules, nodules, and scars. These lesions are typically located on the face and shoulders, although they can extend to the trunk, arms, and legs. In regenerative medicine, biomolecules are fundamental to tissue regeneration. The use of growth factors from autologous platelet-rich plasma emerges as a promising alternative in the treatment of acne and scars. This study [...]

by Sujeet Kumar Thakur  and Sambasivan Venkat Eswaran

Received: 17 June 2023;  Published: 01 September 2023;  doi: 10.21926/rpm.2303032

The Inert soil obtained from the Ghazipur Municipal Solid Waste landfill located in East Delhi, India has been used as the starting material for the work described in this paper. This mountain-like monster is often in the news for its bad smell, pollution of the groundwater in the area from its leachates, and the occasional fires in it endangering the lives of the people living nearby. Landfills produce many greenhouse gases (CO2, CH4, CO, HCHO, H2S, and NH3) which are poisonous and cause environmental pollution in [...]

by Giuseppe Cocco  , Hans Peter Hofmann  and Stefano Pandolfi

Received: 27 December 2023;  Published: 11 March 2024;  doi: 10.21926/obm.geriatr.2401273

Heart failure is one of the major health threats in Western societies, and its prevalence is steadily increasing. Many data show the important impact of sex (biological) and gender (sociocultural) differences on most aspects (diagnosis, etiology, treatments, and outcomes) of heart failure. For example, compared to men, women with heart failure are older, have more co-morbidities, and develop different phenotypes of heart failure. Postpartum cardiopathy is unique in women. The iatrogenic effects of cancer therapies [...]

by Tara Hickey  , Sarah Strohmaier  , Ellie Fossey  and Charlie Heriot-Maitland

Received: 21 December 2023;  Published: 25 April 2024;  doi: 10.21926/obm.icm.2402023

In the compassion focused therapy (CFT) model of voice-hearing, a distressing relationship with voices is thought to be influenced by evolved threat-protection patterns, which are activated and attuned by socially threatening experiences, such as being harmed by others, as well being shamed, stigmatised, invalidated, and excluded. Therefore, the CFT approach is particularly interested in the role of voice-hearers’ relationships with others and self, as well as their social context of family/friends, professio [...]

by Heather J. Leach  , Emma L. Gomes  , Mary C. Hidde  , Kate Lyden  , Angela D. Bryan  , Myles G. Cockburn  and Wells A. Messersmith

Received: 17 July 2023;  Published: 20 December 2023;  doi: 10.21926/obm.icm.2304060

Physical activity (PA) after a colorectal cancer (CRC) diagnosis can improve physical function and quality of life and is associated with decreased mortality rates and longer disease-free survival. The accelerated use of videoconference technology during and following the COVID-19 pandemic offers an opportunity to explore the potential of a virtually supervised intervention to help survivors of CRC increase PA. A two-arm single blind pilot randomized controlled trial of individuals who had completed treatment for C [...]

by Michael Frass

Received: 13 November 2019;  Published: 14 November 2019;  doi: 10.21926/obm.icm.1904063

Highlights of Application of Homeopathy in Oncology Patients: An Interview with Prof. Michael Frass

by Sunil Kumar

Received: 20 October 2022;  Published: 22 January 2024;  doi: 10.21926/aeer.2401004

Generally, automobile vehicles discharge specific contaminants into the surrounding environment during operation, which might affect human and reproductive health. Additionally, a more extended period of sitting while driving is linked with the manifestation of heat in the pelvic region, which might also impact the driver’s semen quality. The data on motor traffic pollution, sitting posture duration while driving, and their impact on reproduction was collected by searching various websites. The data on the effects [...]

by Pier Alberto Testoni  and Sabrina Testoni

Received: 17 October 2019;  Published: 23 December 2019;  doi: 10.21926/obm.hg.1904042

Recurrent acute pancreatitis (RAP) is a clinical entity characterized by episodes of acute pancreatitis which occurs on more than one occasion. Recurrence of pancreatitis generally occurs in a setting of a normal anatomical and functional gland, however, a chronic disease at early stage may be found either on the occasion of the first episode of pancreatitis or during the follow-up. The etiology of RAP can be identified in up to 70% of cases; for the remaining cases the term “idiopathic” is used. Most common caus [...]

by David G Smithard

Received: 24 December 2022;  Published: 07 March 2023;  doi: 10.21926/obm.geriatr.2301225

Ageing: Longevity, Successful and Positive

by Paul Andrew Entwistle

Received: 09 March 2022;  Published: 26 September 2022;  doi: 10.21926/obm.icm.2203046

Much has been written about the aetiological role of Adverse Childhood Experiences (ACEs) in the development of chronic adult physical and emotional health problems but current screening methods utilising questionnaires and formal interviewing often fail to show consensus across populations and surveys. This paper proposes that hypnotic regression might provide an alternative approach to ACE screening through its facility in revealing unsuspected and seemingly minor ACEs, which nevertheless can go on to have long t [...]

by Michael Falkenstein

Received: 11 August 2020;  Published: 19 August 2020;  doi: 10.21926/obm.geriatr.2003130

by Doo-Sung Lee

Received: 09 December 2020;  Published: 02 June 2021;  doi: 10.21926/rpm.2102021

This paper concerns a poroelastic half-space in which plane compressional waves are scattered by a spherical inclusion. Addition theorems for the spherical wave functions are utilized to meet the boundary conditions on the plane, and the satisfaction of the given conditions on the boundary of the sphere leads to three infinite series equations, whose solution can be acquired by successive approximations. Further, its existence and uniqueness are discussed.

by Ludek Fiala  , Jiri Lenz  and Sarka Papadaki

Received: 28 December 2024;  Published: 06 June 2025;  doi: 10.21926/obm.icm.2502023

This research focused on the evaluation of the relationship between the levonorgestrel-releasing intrauterine device and Hypoactive Sexual Desire Disorder in women. Sexual desire disorder is part of a group of sexual dysfunctions. A group of 60 women with a diagnosis of hypoactive sexual desire were tested in the period from July 2023 to July 2024 at the Institute of Sexology of the 1st Faculty of Medicine in Prague. These patients were examined for levels of prolactin, sex hormone binding globulin, total testoster [...]

by Abdulmalik Ahmad Lawan  , Hauwa Zakariyya Abdullahi  , Abdullahi Yunusa Abdullahi  and Sadiya Tahir

Received: 16 January 2025;  Published: 15 August 2025;  doi: 10.21926/obm.neurobiol.2503298

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder associated with significant heterogeneity in symptoms and comorbid conditions. Studies have shown the value of early and accurate diagnosis in mitigating the associated social and behavioral challenges. Recently, studies have demonstrated the potential of machine learning (ML) models in identifying ASD patterns from neuroimaging, genetic, and behavioral data. However, the limited interpretability of these models poses a barrier to their clinical adopti [...]

by Sanju Dahiya  and Munish Garg

Received: 23 August 2023;  Published: 26 March 2024;  doi: 10.21926/rpn.2401004

The world has suffered a lot during the COVID-19 pandemic, for which nobody was prepared. Due to the lack of appropriate treatment, Indian medicinal plants have alleviated the burden due to their diverse health benefits. It has been observed that certain medicinal plants can effectively enhance immunity against microorganisms and viruses. Numerous scientific studies have supported the above claims. This paper presents the SWOC analysis of Indian medicinal plants for their immunity-enhancing effects so that the medi [...]

by John Konstantaras  , Christos Pagkalos  , Maria K. Koukou  , Kostas Lymperis  , Yannis Caouris  and Michail Gr. Vrachopoulos

Received: 17 April 2022;  Published: 09 June 2022;  doi: 10.21926/jept.2202021

In this study, the performance of a self-sufficient controller used for a solar-latent heat domestic hot water (DHW) production unit under real-world operating conditions was analyzed. The unit consists of a flat-plate solar collector and a latent heat storage tank. The controller is powered by a small solar panel and governs the charging and discharging of the system, ensuring maximum solar energy absorption, desired hot water temperature, and constant monitoring of the heat-storage tank’s capacity. The system is [...]

by Mona Liza Santana  , Aline Santos e Santos  , Gildomar L.V. Júnior  and Sandra Aparecida de Assis

Received: 24 December 2022;  Published: 12 June 2023;  doi: 10.21926/cr.2302019

Microorganisms that are capable of degrading lignocellulolytic materials can produce extracellular cellulase complexes. Microorganisms are an excellent alternative for the production of cellulolytic complex, since these sources have a high power of multiplication. In this work, we researched the production by the fungus Moniliophthora perniciosa. The production and pH and temperature optimum optimization were studied by Response surface methodology and carboxymethylcellulase (CMCase) characterization. Thermal stabi [...]

by Peter Jones  and Martin Wynn

Received: 17 February 2024;  Published: 01 April 2024;  doi: 10.21926/jept.2402009

The purpose of this article is to examine the approach to waste management of local authorities in England, to investigate their strategic objectives, and to ascertain to what extent sustainability and circular economy practices are in evidence in this context. A qualitative, inductive research method is used, based on an examination of secondary documentation in three local authorities in England in Birmingham, Bristol and Newcastle upon Tyne. The findings reveal considerable common ground within the three authori [...]

by Nadia A. Abdelmegeed Abdelwahed  , Mohammed A. Al Doghan  and Bahadur Ali Soomro

Received: 25 August 2023;  Published: 24 November 2023;  doi: 10.21926/obm.neurobiol.2304197

In today's corporate landscape, optimizing performance has emerged as a formidable challenge for organizations, often hindered by formidable barriers and psychological factors. This study explores the role of anxiety, stress, and depression in attaining performance among Egyptian construction site workers. The quantitative analysis utilizes cross-sectional data collected from workers working at different construction sites in Egypt. The study concludes with findings from 298 valid cases. Leveraging the structur [...]

by Yogendra Keche  , Preetam Wasneek  , Keshao Nagpure  , Nitin Gaikwad  , Suryaprakash Dhaneria  , Sabah Siddiqui  and Apoorva Joshi

Received: 22 August 2022;  Published: 11 December 2022;  doi: 10.21926/obm.geriatr.2204216

The COVID-19 pandemic had imposed a city-level quarantine, local lockdown, and border closures for patient-level isolation to control virus spread. There is a lack of studies on the health-related quality of life (HRQoL) in the elderly in countries like India during COVID-19. After obtaining written informed consent from the elderly patients, data was recorded in the case record form-cum-questionnaire. The quality of life was assessed with the help of Centers for disease control and prevention (CDC) HRQoL-14 measur [...]

by Matina Lazaraki  , Niki Skopeliti  and Ioannis Syros

Received: 06 January 2025;  Published: 24 March 2025;  doi: 10.21926/obm.neurobiol.2501280

Children's leisure time in the Western world is changing compared to what it used to be in the previous decades. Children's involvement in organized activities and screen time use is increasing, while outdoor play, despite once being the main leisure time activity for children, is declining. Gray, Oliver and other contemporary theorists link this shift in children's lifestyles to an increase in the prevalence of anxiety disorders. This study aimed to determine whether allocating preschool children's [...]