by Wanda Liguigli  , Rita Cengarle  , Anita Rimanti  , Giovanna Catania  , Laura Faglioni  , Simone Voltolini  , Carla Rabbi  , Roberto Barbieri  , Ilenia Zanardi Di Pietro  , Beatrice Vivorio  , Patrizia Morselli  , Chiara Iridile  , Laura Rigotti  and Maurizio Cantore

Received: 26 October 2022;  Published: 27 March 2023;  doi: 10.21926/obm.geriatr.2301230

Comprehensive Geriatric Assessment (CGA) is utilized to plan social and health care of the elderly and to complete the diagnostic-therapeutic choice of oncologist also considering early integration with palliative care. Cancer patients (pts) hospitalized aged ≥70 years were screened by the G8 questionnaire to define if necessary CGA. CGA identified: fit, unfit and frail pts. We screened 95 pts by G8 and 93 (98%) were at risk. Pts at risk, evaluated by CGA resulted: 3 fit, 45 unfit and 45 frail. 3 fit pts received s [...]

by Giuseppe Cocco  , Hans Peter Hofmann  and Stefano Pandolfi

Received: 27 December 2023;  Published: 11 March 2024;  doi: 10.21926/obm.geriatr.2401273

Heart failure is one of the major health threats in Western societies, and its prevalence is steadily increasing. Many data show the important impact of sex (biological) and gender (sociocultural) differences on most aspects (diagnosis, etiology, treatments, and outcomes) of heart failure. For example, compared to men, women with heart failure are older, have more co-morbidities, and develop different phenotypes of heart failure. Postpartum cardiopathy is unique in women. The iatrogenic effects of cancer therapies [...]

by Dipti Nikam  and Abbas S. Milani

Received: 05 May 2022;  Published: 24 April 2023;  doi: 10.21926/rpm.2302017

This study evaluates the influence of different loading angles and the area of loading on the ensuing stress distribution and the physical response of a natural central incisor tooth, using a 3D finite element analysis. The CAD model of the incisor tooth assembly (including enamel, dentin, periodontal ligament, pulp, gingiva and jaw bone) was subject to an external (chewing) load of 100 N, over four different areas and at four different angles along the vertical. It was observed that the tooth experiences high von- [...]

by Charles E. Carraher  , Michael R. Roner  , Jessica Frank  , Paul Slawek  , Francesca Mosca  , Kimberly Shahi  , Alisa Moric-Johnson  and Lindsey Miller

Received: 31 January 2019;  Published: 14 May 2019;  doi: 10.21926/obm.hg.1902019

Pancreatic cancer is the fourth leading cause of death in the USA. Treatment is seldom successful. A wide variety of organotin polymers exhibit good inhibition of human pancreatic cancer cell lines AsPC-1 and PANC-1. The AsPC-1 is an adenocarcinoma pancreatic cell line and PANC-1 which is an epithelioid carcinoma pancreatic cell line. Synthesis is rapid employing commercially available reactants and the interfacial polymerization that is employed in the commercial synthesis of aramids and polycarbonates.

by John Konstantaras  , Christos Pagkalos  , Maria K. Koukou  , Kostas Lymperis  , Yannis Caouris  and Michail Gr. Vrachopoulos

Received: 17 April 2022;  Published: 09 June 2022;  doi: 10.21926/jept.2202021

In this study, the performance of a self-sufficient controller used for a solar-latent heat domestic hot water (DHW) production unit under real-world operating conditions was analyzed. The unit consists of a flat-plate solar collector and a latent heat storage tank. The controller is powered by a small solar panel and governs the charging and discharging of the system, ensuring maximum solar energy absorption, desired hot water temperature, and constant monitoring of the heat-storage tank’s capacity. The system is [...]

by Martina C Cornel

Received: 13 July 2017;  Published: 11 February 2018;  doi: 10.21926/obm.genet.1801013

Technology makes it possible to expand many of the current screening programs. Initiatives for preconception screening of carrier status of recessive diseases, prenatal screening of aneuploidies and neonatal screening were initially undertaken by targeting one or at most, a few, conditions. Tandem mass spectrometry and genomic technologies, such as sequencing and panel testing, make it possible to increase the scope of these programs to include more disorders or markers. While inclusion of a larger number of condit [...]

by Mona Liza Santana  , Aline Santos e Santos  , Gildomar L.V. Júnior  and Sandra Aparecida de Assis

Received: 24 December 2022;  Published: 12 June 2023;  doi: 10.21926/cr.2302019

Microorganisms that are capable of degrading lignocellulolytic materials can produce extracellular cellulase complexes. Microorganisms are an excellent alternative for the production of cellulolytic complex, since these sources have a high power of multiplication. In this work, we researched the production by the fungus Moniliophthora perniciosa. The production and pH and temperature optimum optimization were studied by Response surface methodology and carboxymethylcellulase (CMCase) characterization. Thermal stabi [...]

by David G Smithard

Received: 24 December 2022;  Published: 07 March 2023;  doi: 10.21926/obm.geriatr.2301225

Ageing: Longevity, Successful and Positive

by Peter Jones  and Martin Wynn

Received: 17 February 2024;  Published: 01 April 2024;  doi: 10.21926/jept.2402009

The purpose of this article is to examine the approach to waste management of local authorities in England, to investigate their strategic objectives, and to ascertain to what extent sustainability and circular economy practices are in evidence in this context. A qualitative, inductive research method is used, based on an examination of secondary documentation in three local authorities in England in Birmingham, Bristol and Newcastle upon Tyne. The findings reveal considerable common ground within the three authori [...]

by Elga J. Vargas  , Julio C. Martinez  and Lina A. Gomez

Received: 26 April 2024;  Published: 03 October 2024;  doi: 10.21926/obm.transplant.2404225

Acne is a chronic inflammatory condition affecting the pilosebaceous units of the skin, characterized by the formation of papules, cysts, comedones, pustules, nodules, and scars. These lesions are typically located on the face and shoulders, although they can extend to the trunk, arms, and legs. In regenerative medicine, biomolecules are fundamental to tissue regeneration. The use of growth factors from autologous platelet-rich plasma emerges as a promising alternative in the treatment of acne and scars. This study [...]

by Filippo Lixi  , Benedetta Pintus  and Giuseppe Giannaccare

Received: 27 February 2024;  Published: 07 June 2024;  doi: 10.21926/obm.transplant.2402218

Calcareous corneal degeneration is a rare disease characterized by calcium phosphate deposition into the deep corneal layers. Corneal calcification has a multifactorial origin and is associated with various systemic and ocular conditions. Several treatment options showed promising results in the management of this disorder. Herein, two cases of calcareous degeneration occurring postoperatively in patients undergoing surgery for retinal detachment (case #1) and glaucoma (case #2) were reported. Despite normal serum [...]

by Nadia A. Abdelmegeed Abdelwahed  , Mohammed A. Al Doghan  and Bahadur Ali Soomro

Received: 25 August 2023;  Published: 24 November 2023;  doi: 10.21926/obm.neurobiol.2304197

In today's corporate landscape, optimizing performance has emerged as a formidable challenge for organizations, often hindered by formidable barriers and psychological factors. This study explores the role of anxiety, stress, and depression in attaining performance among Egyptian construction site workers. The quantitative analysis utilizes cross-sectional data collected from workers working at different construction sites in Egypt. The study concludes with findings from 298 valid cases. Leveraging the structur [...]

by Kevin Bobeck  , Sarah Ordway  , Brett Sadowski  , Adam Tritsch  and Manish Singla

Received: 31 January 2019;  Published: 28 June 2019;  doi: 10.21926/obm.hg.1902025

Diseases of the liver are commonly encountered in patients with Inflammatory Bowel Disease (IBD). While the differential for IBD patients with elevated liver associated enzymes is broad, it is similar to that of the general population. This differential includes including non-alcoholic fatty liver disease (NAFLD), the most common liver disease in North America. When initial work-up for elevated liver associated enzymes is negative and patients have steatosis on ultrasound, we counsel IBD patients aggressively about [...]

by Sanju Dahiya  and Munish Garg

Received: 23 August 2023;  Published: 26 March 2024;  doi: 10.21926/rpn.2401004

The world has suffered a lot during the COVID-19 pandemic, for which nobody was prepared. Due to the lack of appropriate treatment, Indian medicinal plants have alleviated the burden due to their diverse health benefits. It has been observed that certain medicinal plants can effectively enhance immunity against microorganisms and viruses. Numerous scientific studies have supported the above claims. This paper presents the SWOC analysis of Indian medicinal plants for their immunity-enhancing effects so that the medi [...]

by Prasanna N. de Silva

Received: 10 September 2020;  Published: 26 November 2020;  doi: 10.21926/obm.neurobiol.2004078

This study looked at secondary care utilization metrics as an effectiveness indicator of Clozapine initiation in 77 patients over the following year compared to the year prior to initiation. It was found that there was a marginal drop in psychiatric bed utilization, alongside reduced crisis team use. Medical and psychiatric outpatient use increased, as did physical health interventions. Overall, compared with costs over the year preceding Clozapine initiation, an estimated saving per patient of £3,867 (5,065) was a [...]

by Yogendra Keche  , Preetam Wasneek  , Keshao Nagpure  , Nitin Gaikwad  , Suryaprakash Dhaneria  , Sabah Siddiqui  and Apoorva Joshi

Received: 22 August 2022;  Published: 11 December 2022;  doi: 10.21926/obm.geriatr.2204216

The COVID-19 pandemic had imposed a city-level quarantine, local lockdown, and border closures for patient-level isolation to control virus spread. There is a lack of studies on the health-related quality of life (HRQoL) in the elderly in countries like India during COVID-19. After obtaining written informed consent from the elderly patients, data was recorded in the case record form-cum-questionnaire. The quality of life was assessed with the help of Centers for disease control and prevention (CDC) HRQoL-14 measur [...]

by Hülya Çakmur

Received: 23 March 2023;  Published: 14 August 2023;  doi: 10.21926/obm.geriatr.2303245

The geriatric population is increasing all over the world. Aging people have special health requirements and comprehensive medical checkups prevent physical, functional and mental decline during the aging period. This study aimed to examine the fitness level and identify problems with the well-being of elderly persons. In this context, the study also attempted to determine the relationship between socio-demographic factors and the health status of elderly adults. In this cross-sectional study, 168 elderly adults (≥ [...]

by Heather J. Leach  , Emma L. Gomes  , Mary C. Hidde  , Kate Lyden  , Angela D. Bryan  , Myles G. Cockburn  and Wells A. Messersmith

Received: 17 July 2023;  Published: 20 December 2023;  doi: 10.21926/obm.icm.2304060

Physical activity (PA) after a colorectal cancer (CRC) diagnosis can improve physical function and quality of life and is associated with decreased mortality rates and longer disease-free survival. The accelerated use of videoconference technology during and following the COVID-19 pandemic offers an opportunity to explore the potential of a virtually supervised intervention to help survivors of CRC increase PA. A two-arm single blind pilot randomized controlled trial of individuals who had completed treatment for C [...]

by OBM Transplantation Editorial Office

Received: 06 January 2022;  Published: 07 January 2022;  doi: 10.21926/obm.transplant.2201157

The editors of OBM Transplantation would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recogni [...]

by Paul Andrew Entwistle

Received: 09 March 2022;  Published: 26 September 2022;  doi: 10.21926/obm.icm.2203046

Much has been written about the aetiological role of Adverse Childhood Experiences (ACEs) in the development of chronic adult physical and emotional health problems but current screening methods utilising questionnaires and formal interviewing often fail to show consensus across populations and surveys. This paper proposes that hypnotic regression might provide an alternative approach to ACE screening through its facility in revealing unsuspected and seemingly minor ACEs, which nevertheless can go on to have long t [...]

by Hunter Heineman  , Omran Omar  , Benjamin Rippel  , Ryan Keeley  , Michael Mehan  , Surendra Gupta  and Gerald A. Takacs

Received: 21 August 2022;  Published: 06 December 2022;  doi: 10.21926/jept.2204040

Ozone was reacted with the aromatic membrane polyetheretherketone (PEEK) to form oxidized functional groups on the surface to enhance the attraction and transport of protons in fuel cells. Ozonation of unsaturated C-C sp2 bonds in PEEK formed a primary ozonide which dissociated to primarily produce O=C-O/O=C-OH moieties, and the root mean squared roughness factor (Rq) decreased from 7.4 nm, for the untreated sample, down to 3.1 nm. The oxidation of the surface and decrease in surface roughness made the surface incr [...]

by Lie Zhang  , Reza D. Fakhrabadi  , Maryam Khoshkhoo  and Husien Salama

Received: 29 December 2021;  Published: 09 October 2022;  doi: 10.21926/jept.2204031

Integrating large-scale wind energy in modern power systems necessitates high-efficiency mathematical models to address classical assumptions in power systems. In particular, two main assumptions for wind energy integration in power systems have not been adequately studied. First, nonlinear AC power flow equations have been linearized in most of the literature. Such simplifications can lead to inaccurate power flow calculations and result in technical issues. Second, wind power uncertainties are inevitable and have [...]

by Elvira A. Guseinova  and Samira R. Safarova

Received: 28 July 2022;  Published: 26 October 2022;  doi: 10.21926/cr.2204037

In this study, we found that adding catalytic cracking feedstock, vacuum gas oil, and naphthenic acids in the amount of 0.005–0.0075% vol. increased the liquid target fractions, i.e., gasoline and light gas oil. The decrease in the yield of hydrocarbon gas at a practically constant degree of conversion of the raw material indicated a small proportion of the reactions of re-cracking of the resulting products. This also indicated the resource-saving nature of the process, allowing a larger amount of gasoline fraction [...]

by Julia Henderson

Received: 05 November 2019;  Published: 17 January 2020;  doi: 10.21926/obm.geriatr.2001101

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by Haris Muhammad  , Muhammad Hammami  , Peng-sheng Ting  , Cem Simsek  , Behnam Saberi  and Ahmet Gurakar

Received: 02 February 2020;  Published: 24 April 2020;  doi: 10.21926/obm.hg.2002046

Liver transplantation has steadily increased worldwide resulting in a large number of patients on the waiting list. Due to the opioid epidemic in the US, the pool of Hepatitis C seropositive donors increased significantly in recent years. Direct acting antivirals played an instrumental role in making liver transplantation with hepatitis C positive allograft an acceptable option. Although hepatitis C positive liver transplantation to hepatitis C positive recipients is a common practice, there is limited data and agr [...]