Table of Content

Open Access Editorial

OBM Transplantation—A New Hub in the Network of Transplantation Science

Received: 07 April 2017;  Published: 11 April 2017;  doi: 10.21926/obm.transplant.1701001

1114 9677

Open Access Original Research

Generalized Normal Distribution Optimization Algorithm for Economic Dispatch with Renewable Resources Integration

Received: 18 June 2023;  Published: 28 September 2023;  doi: 10.21926/jept.2303030

Abstract

In an electric power system operation, the main goal of economic dispatch (ED) is to schedule the power outputs of committed generating units efficiently. This involves consideration of relevant system equality and inequality constraints to meet the required power demand at the lowest possible operational cost. This is a challenging optimization problem for power system operators that can be dealt with efficient meta-heuristic algorithms. This article uses a recent meta-heuristic approach named the generalized norm [...]

1430 9670

Open Access Review

The Relationship between Pneumocystis Infection in Animal and Human Hosts, and Climatological and Environmental Air Pollution Factors: A Systematic Review

Received: 14 September 2018;  Published: 25 October 2018;  doi: 10.21926/obm.genet.1804045

Abstract

Background: Over the past decade, there has been rising interest in the interaction of Pneumocystis with the environment. This interest has arisen in part from the demonstration that environmental factors have important effects on the viability and transmission of microbes, including Pneumocystis. Environmental factors include climatological factors such as temperature, humidity, and precipitation, and air pollution factors including carbon monoxide, nitrogen dioxide, sulfur dioxide, and particulate matter. Methods [...]

2251 9667

Open Access Case Report

Influence of Wetting-Drying Cycles on Wood Behaviour of Coastal Pedestrian Walkways

Received: 30 September 2022;  Published: 11 January 2023;  doi: 10.21926/rpm.2301004

Abstract

In the context of inspection and maintenance actions for beach walkways in the North of Portugal, some samples of wood used in their construction were collected – the Pinus sylvestris wood, widely applied in the country. The sustainability of the beach walkways over natural coastal areas is very dependent on their material durability. One of the main problems of the timber used to build those structures is its behavior under wet-drying cycles. For that reason, this work aimed to simulate the effects of weathering o [...]

1386 9667

Open Access Review

Episomal Vectors: Principle, Utility, and Application

Received: 31 August 2025;  Published: 24 November 2025;  doi: 10.21926/obm.genet.2504317

Abstract

An episomal vector is a plasmid- or virus-based vector that is present extrachromosomally in cells after transfection. Although it disappears during cell proliferation, it can exist in non-dividing cells, such as neuronal and muscular cells, and continues to express a gene of interest (GOI). Such episomal vectors are usually based on sequences from DNA viruses such as bovine papillomavirus 1 and Epstein-Barr virus. When cells are transfected with an episomal vector harboring a drug-resistance gene and subsequently [...]

1738 9663

Open Access Editorial

Epigenetics of Obesity and Diabetes: Emerging Roles and Mechanisms of Non-coding RNAs

Received: 16 March 2020;  Published: 17 March 2020;  doi: 10.21926/obm.genet.2001105

1915 9662

Open Access Case Report

Dietary Supplements in Dyslipidemia

Received: 04 March 2018;  Published: 23 May 2018;  doi: 10.21926/obm.icm.1802008

Abstract

Lifestyle and dietary interventions can have a significant impact on patients with dyslipidemia and should be encouraged with the use of dietary supplements. With new research, there is evidence that using dietary supplements, specifically nutraceuticals can be helpful for cholesterol management. Four commonly used supplements are: Red Yeast Rice, Omega 3 Fatty Acids, Niacin and Berberine.

1950 9659

Open Access Perspective

Diabetes and Obesity

Received: 18 August 2021;  Published: 22 November 2021;  doi: 10.21926/obm.icm.2104048

Abstract

Obesity and Diabetes are leading causes of cardiovascular disease and mortality. They are closely linked because of insulin resistance. Hypertension and dyslipidaemia together with poor exercise drive atherosclerosis. Early treatment of blood sugar, dyslipidaemia and hypertension reverse the atherosclerosis process. Bariatric surgery and low calorie diets have in recent years been shown to reverse or improve blood sugars lipids and blood pressure. The risk of premature myocardial infarction and death should no long [...]

1675 9658

Open Access Original Research

Who Believes in Fake News: A Study on the Relationship between Affective Temperament, Cyberchondria and Problematic Use of the Internet during the COVID-19 Pandemic

Received: 02 November 2022;  Published: 12 January 2023;  doi: 10.21926/obm.neurobiol.2301151

Abstract

The COVID-19 outbreak has been associated with various psychological problems, such as Cyberchondria, constant research for information online, to obtain health-related information. This was associated with problematic social media use and various psychological problems. This study aimed to measure the characteristics of fear and anxiety of COVID-19, the generalized approach to online searching and the use of the Internet about the perception of health, during a pandemic. The online survey was disseminated from Apr [...]

1434 9655

Open Access Review

The Potential Impact of COVID-19 on Depression and Suicide Risk in Older Adults

Received: 19 January 2021;  Published: 24 December 2021;  doi: 10.21926/obm.neurobiol.2104112

Abstract

COVID-19 infections, hospitalizations, and deaths continue to skyrocket across the world, leaving a trail of enduring psychological turmoil. It wreaks havoc on the physical, emotional, and cognitive health of those directly infected, as well as caretakers, friends, and families. Though the pandemic has at least indirectly impacted most people, older adults appear to be the most vulnerable to COVID-19-related deaths and little is known about the psychological consequences. Unfortunately, many of the precautions take [...]

1224 9653

Open Access Case Report

Hypereosinophilia with Gastrointestinal Involvement: A Case Report

Received: 29 September 2019;  Published: 22 November 2019;  doi: 10.21926/obm.hg.1904040

Abstract

Hypereosinophilic syndrome is currently defined by an absolute blood eosinophil count of more of 1500 cell per μL for more than 1 month and by multiorgan system infiltration. Eosinophilic colitis is an exceptionally rare inflammatory condition in which eosinophils infiltrate the colonic gut. It represents the least frequent manifestation of the wide spectrum of eosinophilic gastrointestinal disorders. We describe a case of an adult male patient with persistent eosinophilia for at least twenty-five years. During thi [...]

1500 9647

Open Access Original Research

Establishment of an In Vitro Propagation, Transformation, and Gene Editing System in Tomato (Solanum lycopersicum)

Received: 12 January 2024;  Published: 18 June 2024;  doi: 10.21926/obm.genet.2402244

Abstract

Tomato (Solanum lycopersicum), a family of Solanaceae, is an annual crop grown in fields and greenhouses. Tomato is the fourth-largest agricultural crop in the world, with a market value of more than $50 billion. Numerous attempts were conducted on the tomato for further improvement via in vitro regeneration and transformation. This study aims to establish in vitro multiplication, transformation, and gene editing systems in tomatoes by using cotyledon explants. Cotyledon explants were placed on the MS medium suppor [...]

1579 9643

Open Access Review

Systematic Review of High-Dimensional Omics in Mind-Body Medicine

Received: 27 March 2022;  Published: 05 December 2022;  doi: 10.21926/obm.icm.2204052

Abstract

The multi-dimensional measurement of complex biological systems and sub-systems is made possible by high-dimensional omics technologies. This frontier of research is promising for elucidating disease processes, physiological parameters, and therapeutic action mechanisms. Omics have potential merit for the integrative medicine field that is relatively early in terms of mechanistic research towards understanding the underlining therapeutic processes of mind-body interventions that show to affect multiple systems simu [...]

1632 9634

Open Access Review

Fall Prevention Knowledge and Attitude Tests-Surveys Used by Staff and Nurses: A Systematic Review of Current Literature

Received: 01 February 2025;  Published: 26 June 2025;  doi: 10.21926/obm.geriatr.2502317

Abstract

Falls are a serious global public health issue affecting individuals of all ages, resulting in serious injuries, fatalities, and extended hospital stays. While knowledge and attitude of healthcare staff toward fall prevention are understood to impact patient safety, less well known are the type and content of fall prevention surveys used to identify nurses’ knowledge of fall prevention. Until now, no study has systematically reviewed the universe of existing tests, surveys, and programs used to assess fall pr [...]

1468 9629

Open Access Research Article

What Do We Know about an Invisible Issue? Results of a Scoping Review of Elder Abuse and Gender and Sexual Minorities

Received: 04 January 2024;  Published: 18 March 2024;  doi: 10.21926/obm.geriatr.2401274

Abstract

Elder abuse occurs to older adults who are members of gender and sexual minorities (GSM). Whilst most of that abuse is similar to that experienced by their heterosexual and cisgender peers GSM older adults face particular vulnerabilities due to their life experiences and changes. In this article we report on our findings from a literature search and knowledge synthesis, conducted as part of a larger project to inform Canadian policy makers working to eliminate gender and sexuality-based inequalities. The review inc [...]

1494 9619

Open Access Review

Functional Prognosis of Spinal Cord Injury Due to Spinal Tuberculosis

Received: 03 October 2024;  Published: 18 March 2025;  doi: 10.21926/obm.neurobiol.2501279

Abstract

Spinal tuberculosis (TB), an extrapulmonary manifestation of TB, primarily involves one or multiple vertebrae, with a high prevalence at the thoracolumbar region, which can compromise spinal cord integrity and result in severe sequelae such as paraplegia, bladder and bowel dysfunction, and mobility limitation. This study aimed to review medical, surgical, and rehabilitation management, clinical outcomes, and prognostic factors of spinal TB with spinal cord injury (SCI). Research was conducted utilizing databases su [...]

1443 9619

Open Access Review

Allogeneic Hematopoietic Cell Therapies to Induce Tolerance in Kidney Transplantation

Received: 29 October 2018;  Published: 20 November 2018;  doi: 10.21926/obm.transplant.1804027

Abstract

This review summarizes the latest results from the interventional clinical trials for inducing clinical tolerance in the recipients of human leukocyte antigen (HLA)-matched or mismatched living donor kidney transplants via allogeneic hematopoietic stem cell (HSC)-based therapies. The protocols utilized by the three medical centers in the United States differ in degree of HLA-matching, relatedness or unrelatedness, donor cell composition of the hematopoietic stem cells transplant (HSCT), timing for infusion and cond [...]

1644 9609

Open Access Research Article

The Lived Experience of Individuals with Chronic Traumatic Brain Injury: An Adapted Group Yoga Intervention

Received: 04 November 2018;  Published: 16 December 2018;  doi: 10.21926/obm.icm.1804033

Abstract

Background: An adapted yoga intervention was delivered to seven individuals with chronic traumatic brain injury. The purpose of this study was to explore and describe the participants' experience of engaging in the 8-week intervention. Methods: Using a phenomenological design, data were collected, analyzed, and coded to generate themes regarding experiences that occurred, how experiences occurred, and why experiences occurred. Results: Participants described experiencing the yoga intervention as a process: from ini [...]

1523 9607

Open Access Short Report

The Brazilian Research Scenario in Green Hydrogen: A Brief Contextualization

Received: 18 April 2024;  Published: 11 November 2024;  doi: 10.21926/jept.2404020

Abstract

Hydrogen is crucial in various industrial sectors and can be obtained through different synthesis routes. However, a significant portion of its production still relies on chemical processes involving fossil fuels, resulting in hydrogen and the generation of greenhouse gases (GHGs) as the final byproduct. In alignment with the goals of the 2030 Agenda, where countries commit to implementing energy transition, hydrogen obtained through a green route has been increasingly explored by governmental and academic entities [...]

1968 9604

Open Access Review

Molecular Plant Physiology for Model Plants under Abiotic Stress Conditions

Received: 23 December 2023;  Published: 24 April 2024;  doi: 10.21926/obm.genet.2402230

Abstract

Extreme temperatures, drought, and high soil salinity are some of the significant abiotic stresses that can severely impact crop yields, posing a threat to global food production. Comprehensive studies on model plant species are crucial for understanding their biochemical, physiological, and molecular responses to abiotic stresses. Identifying stress response mechanisms and potential targets can aid in developing stress-tolerant crop varieties. Additionally, elucidating the functions of reactive oxygen species is e [...]

1409 9600

Open Access Review

Reflexes and Shared Intentionality in the Origins of Emotions Development: A Scoping Review of Studies on Blinking in Infants

Received: 16 August 2024;  Published: 10 January 2025;  doi: 10.21926/obm.neurobiol.2501263

Abstract

This review aims to explore research on the development of emotions in organisms at the simple reflexes substage of the sensorimotor stage of cognitive development. We review the literature on alterations in spontaneous blinking in children under 6 months of age. Then, we extract the data from the selected studies that allow us to examine whether simple reflexes in infants reveal the emotion signature in the altered reflective responses. The significance of this study is that it is the first review to demonstrate t [...]

916 9594

Open Access Research Article

Drainage in a Screw Press and Utilization of the Recovered Fibres after Thermo-Hydrolytic Disintegration of Waste Fibreboards

Received: 15 March 2021;  Published: 22 July 2021;  doi: 10.21926/rpm.2103029

Abstract

A thermo-hydrolytic disintegration process qualifies as a promising option for recycling the waste MDF and preserving the fibrous morphology of the recovered lignocellulosic fibre material. This study aims to include a drainage process between the thermo-hydrolytic disintegration and the further utilization of the recovered fibres (RF) obtained using a screw press for removing the disintegration water (DW). In this context, the chemical properties of the RF (pH, nitrogen content, formaldehyde emissions) and the DW [...]

2011 9585

Open Access Original Research

Historical Evolution and Scenarios Up to 2050 of Heating Energy Consumption and CO2 Emissions of Residential Buildings in Vienna

Received: 24 June 2022;  Published: 27 September 2022;  doi: 10.21926/jept.2203030

Abstract

Today, the building sector poses a major problem concerning fossil fuel energy consumption and the corresponding emissions of local pollutants and global greenhouse gases (GHG). In addition, an increasing number of people are living in urban areas, and it is becoming challenging to provide the necessary living space and energy for heating in fast-growing cities. Currently, urban areas host approximately 50 % of the global population and generate 70 % of GHG. The core objective of this study is to analyze the histor [...]

1368 9582

Open Access Review

The Relation between Environmental Risk Analysis and the Use of Nanomaterials in the Built Environment Sector: A Circular Economy Perspective

Received: 02 August 2022;  Published: 11 January 2023;  doi: 10.21926/rpm.2301005

Abstract

Nowadays, the challenge of climate change and “ecological transition” is substantially an “energy challenge” for every city, which is supposed to become as “energetically self-sufficient” as possible. The construction sector is one of the main contributors to the effects of climate change, starting from the production of materials to the use phase of buildings to their demolition. Recent innovations in sustainable/circular design are related to using “new materials." According to this perspective, nanomaterials are [...]

1752 9582

Open Access Research Article

Post-Mortem Comparison of the Incidence and the Distribution of Cerebrovascular Lesions Using Additional 7.0-Tesla Magnetic Resonance Imaging in Cognitive Normal Young, Middle-Aged, and Elderly Persons

Received: 06 April 2020;  Published: 04 June 2020;  doi: 10.21926/obm.geriatr.2002122

Abstract

Regional brain atrophy and an escalation in vascular risk are associated to increasing age in normal cognitive healthy persons. The present post-mortem study compares the incidence of cerebrovascular lesions between young-aged, middle-aged, and elderly cognitive normal persons with additional 7.0-tesla MRI). The patients consisted of 10 young adults, 20 middle-aged adults, and 14 elderly ones. In addition to the macroscopic visible cerebrovascular lesions, a whole coronal section of a cerebral hemisphere was taken [...]

1667 9580

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