by Enrico Facco

Received: 04 February 2020;  Published: 08 July 2020;  doi: 10.21926/obm.icm.2003032

The topic of resilience is of paramount importance. Although the term resilience was coined in the fields of physics and engineering, its use has spread to the fields of social sciences, biology, psychology, and psychiatry, as well as to the industry. Moreover, the term is now endowed with a wide range of meanings. The topic of resilience plays a central role in all critical life events. It is of paramount importance in medicine as well as in psychology and psychotherapy, where it is involved in both psychiatric di [...]

by Michele Bisceglia  , Stefano Pizzolitto  , Tullio Parracino  , Giovanna De Maglio  , Elena Minenna  , Serena D’Agostini  and Carlos A. Galliani

Received: 07 October 2018;  Published: 14 November 2018;  doi: 10.21926/obm.neurobiol.1804016

Thyroid transcription factor 1 (TTF-1) is a nuclear polypeptide and a tissue-restricted member of the homeobox protein family that, when attached to DNA, plays a crucial role in regulating the expression of select genes during early embryonic development of the thyroid, lung, and brain. As often happens, the initial enthusiasm for the diagnostic value of TTF-1 as a selective immunohistochemical marker of lung and thyroid tumors began to dwindle, due to its detection in tumors arising from other organs. TTF-1-expres [...]

by Consuelo C. Casula

Received: 18 January 2020;  Published: 27 February 2020;  doi: 10.21926/obm.icm.2001010

This article is based on the assumption that the therapist's focused attention, open awareness and kind intention are the basic ingredients for creating a relationship of trust with the patient from the first session. He also stresses that when the attention of a genuine therapist, without prejudice or judgment, is centered on how the patient expresses him/herself and on the contents s/he proposes, the patient relies more easily on the competent care of the therapist. The author argues that to empower patients it i [...]

by Hanny Tanasal  , Iline Michaela  and Retno Danarti

Received: 28 October 2024;  Published: 08 January 2025;  doi: 10.21926/obm.genet.2501281

Harlequin ichthyosis (HI) is among the most severe hereditary skin conditions of autosomal recessive congenital ichthyosis (ARCI) in newborns, associated with a mutation of the ABCA12 gene. Patients have a typical clinical appearance at birth. A thick layer of armor-like scales covers the entire body. Affected newborns have abnormal facial features, such as ectropion, eclabium, and ears and nose flattening. Although HI was formerly assumed to be fatal, more intensive neonatal care and early retinoid therapy may imp [...]

by Maggie MacKinnon  , Maibritt Pedersen Zari  and Daniel K. Brown

Received: 13 August 2021;  Published: 09 November 2021;  doi: 10.21926/aeer.2104029

The practice of reconciliation ecology in urban environments relies heavily on urban green space as the primary source of vegetated habitat in cities. However, most cities lack the quantity, connectivity, and accessibility of green space needed to provide essential ecosystem services for the health, well-being, and resilience of human and non-human species. In reaction to urban densification and the increasing frequency and severity of climate change impacts, this study argues that architecture could strategically [...]

by Mitsuko Hirosawa  , Koji Hayakawa  , Kunio Shiota  and Satoshi Tanaka

Received: 05 July 2018;  Published: 17 September 2018;  doi: 10.21926/obm.genet.1803036

Histone modifications play an important role in the control of DNA-based processes by altering the structure and function of chromatin. O-linked N-acetylglucosamine (O-GlcNAc) modification is a form of post-translational modification of proteins that affects the serine (Ser)/threonine (Thr) residues. This process is controlled by a single pair of enzymes, i.e. O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). Recent evidence indicates the existence of O-GlcNAc modification of histones, with 16 histone O-GlcNAc site [...]

by Yang Eun Kim  and Boram Lee

Received: 07 March 2024;  Published: 21 May 2024;  doi: 10.21926/obm.neurobiol.2402224

Preschool teachers are at high risk of depression. Therefore, emphasis should be placed on evaluating a valid and reliable instrument to measure depressive symptomatology for this population. One such promising instrument is the Beck Depression Inventory (BDI-II), a 21-item self-report measure designed to assess the presence and severity of depression. Although the tool’s psychometric properties have been analyzed in different samples, they have not been validated with a Korean preschool teacher sample. Hence, this [...]

by Oscar Daoura  , Maya Boutros  and Franck Launay

Received: 01 September 2020;  Published: 26 January 2021;  doi: 10.21926/jept.2101007

CO2 reforming of CH4, also referred to as the Dry Reforming of Methane (DRM), is considered an excellent method to produce H2 and CO (syngas), which are known to be used for the production of higher alkanes and oxygenates. Despite nickel’s moderate toxicity, Ni-based heterogeneous catalysts are considered excellent candidates for use in DRM due to their reasonable performances and economic advantages. However, these materials also present severe drawbacks, such as sintering of the active phase and coke (carbo [...]

by Ankit Patel  , Kevin Houston  , Michael Saadeh  , Ana Vilela  , Byung-Soo Yoo  , Steve M. D’Souza  and David A. Johnson

Received: 24 April 2022;  Published: 01 August 2022;  doi: 10.21926/rpn.2203018

Colorectal cancer (CRC) is currently the third most common cancer within the United States among both males and females, with increasing rates occurring in younger individuals compared to the past. Multiple environmental and social aspects including diet may be contributing to this increase in CRC rates. The aim of this review is to examine foods containing high fructose corn syrup, processed meats, and red meats which have shown to be linked to an increase in incidence of CRC. These foods can be a cause for disrup [...]

by Suhail Hyder Vattathurvalappil  , Syed Fahad Hassan  and Mahmoodul Haq

Received: 24 January 2023;  Published: 16 March 2023;  doi: 10.21926/rpm.2301012

Thermoplastics polymers like Acrylonitrile Butadiene Styrene (ABS) are often reinforced with nano/micro reinforcements to enhance their mechanical, thermal and electrical properties. However, the viscoelastic nature of these polymers results in their strong dependence on the applied strain rate and temperature sensitivity, leading to their characterization complexity. Hence it is paramount to study the strain rate-dependent mechanics of neat ABS. In this study, the effect of strain rate and temperature on Young’s m [...]

by Christopher H. Vane  , Alexander W. Kim  , Darren Beriro  , Mark R. Cave  , Stephen R. Lowe  , Raquel A. Lopes dos Santos  , Antonio M. P. J. Ferreira  , Christopher Collins  , C. Paul Mathanail  and Vicky Moss-Hayes

Received: 05 March 2021;  Published: 28 May 2021;  doi: 10.21926/aeer.2102012

Total organic carbon (TOC), black carbon (BC), total petroleum hydrocarbons (TPH), polycyclic aromatic hydrocarbons (PAH) and polychlorinated biphenyls (PCB) were determined in 73 surface (0-2 cm) and subsurface (5-20 cm) soil samples taken from a 142 km2 area in Central London, UK. Soils were assessed to provide a baseline chemistry for site owners, developers, occupiers and regulators involved in understanding the potential risk to human health and the environment. TOC range was 1.75-11.85 % (mean 5.82 %), BC 3.7 [...]

by Siamak Shirani Bidabadi  , Parisa Sharifi  and S. Mohan Jain

Received: 09 June 2021;  Published: 15 September 2021;  doi: 10.21926/obm.genet.2103137

Plant breeding programs have used conventional breeding methods, such as hybridization, induced mutations, and other methods to manipulate the plant genome within the species' natural genetic boundaries to improve crop varieties. However, repeatedly using conventional breeding methods might lead to the erosion of the gene reservoir, thereby rendering crops vulnerable to environmental stresses and hampering future progress in crop production, food and nutritional security, and socio-economic benefits. Integrating in [...]

by Kamalakanta Sahoo  , Richard Bergman  and Poonam Khatri

Received: 24 August 2021;  Published: 21 December 2021;  doi: 10.21926/rpm.2104049

According to the United Nations Environment Programme (UNEP), the construction and operation of buildings accounted for nearly 38% of total global energy-related CO2 emissions in 2019. The construction sector has been striving to use more low-carbon footprint building products to mitigate climate change and enhance environmentally preferable purchasing. Over the last several decades, there has been substantial growth in engineered wood products for the construction industry. To assess these products used in constru [...]

by Sahar M Afeef  , Laura A Barrett  , Julia K Zakrzewski-Fruer  and Keith Tolfrey

Received: 30 March 2022;  Published: 15 August 2022;  doi: 10.21926/rpn.2203020

Exercise-induced moderation of postprandial glycaemia in adolescents is unclear and has not been examined under free-living conditions. We assessed the effect of moderate-intensity exercise (MIE) and high-intensity intermittent exercise (HIIE) bouts on subsequent postprandial glycaemic responses across three standard school days. Fourteen healthy adolescents (13 ± 1 years) completed three conditions in the following order across consecutive days: MIE, 30-min continuous brisk walking; CON, no-exercise control; HIIE, [...]

by Jordin Lane  and Kevin R. Fontaine

Received: 28 December 2020;  Published: 21 April 2021;  doi: 10.21926/obm.icm.2102015

Carbohydrate-restricted ketogenic diets (KD) were introduced in the mid-19th century as a weight loss method with a resurgence of its use in epilepsy treatment in the 1920’s. Research conducted over the last several years provides evidence that KD’s can confer beneficial effects for several chronic metabolic diseases, including obesity, type-2 diabetes, and polycystic ovary syndrome. In recent years, emerging evidence suggests KD’s may also have therapeutic benefits for some cancers and for neurological conditions [...]

by Vasilios M. Polymeropoulos

Received: 01 August 2020;  Published: 26 October 2020;  doi: 10.21926/obm.icm.2004042

There is a dramatic need for extensive research into the predictors of severe infection with SARS-CoV2 and therapeutic options for infected people. People who suffer from severe illness and higher mortality display a pattern of having specific co-morbidities (diabetes, obesity, hypertension) and are of higher age. Recent research has described methods of viral entry via receptors (ACE2, TMPRSS2) and the hyper-inflammatory state often associated with severe illness (increase in interleukins, increase in TNF-alpha). [...]

by Marie Jardine  , Anna Miles  and Jacqui Allen

Received: 07 November 2020;  Published: 25 December 2020;  doi: 10.21926/obm.geriatr.2004146

Generalisations and misconceptions about ageing and swallowing can influence clinical opinion. Assumptions about swallowing function based on someone’s age risk overmedicalising or, conversely, undertreating older patients. Evidence suggests that increased prevalence of swallowing problems in older age is attributed to pathology known to affect swallowing function, or an unrelated serious illness and combination of health factors, and not ageing itself. This review highlights factors clinicians should consider when [...]

by Claudia Harper  , Radhika Seimon  , Brendon Yee  , Amanda Salis  and Elizabeth Cayanan

Received: 21 February 2022;  Published: 27 May 2022;  doi: 10.21926/rpn.2202015

We report the case of a 30-year-old male with significant obesity (body mass index 47 kg/m2) with co-existing moderate obstructive sleep apnoea, hypertension, hypercholesteremia and hypogonadotropic hypogonadism, who was treated with a very-low-energy diet (VLED) and lifestyle modification programme for 12 months. The patient lost weight throughout the entire treatment period (average weight loss was 2.1 kg/week, for a total of 42.7 kg), and showed marked improvement in co-morbidities and no adverse effects. This c [...]

by Athanasia Soultana  , Michael Galetakis  , Anthoula Vasiliou  , Konstantinos Komnitsas  and Despina Vamvuka

Received: 11 February 2021;  Published: 17 August 2021;  doi: 10.21926/rpm.2103035

Waste concrete is the most predominant constituent material among construction and demolition waste. Current waste concrete recycling is limited to the use of recycled concrete aggregates as a road-base material and less as aggregates in new concrete mixes. Further, the production of recycled concrete aggregates results in the generation of a high amount of fines, consisting mainly of cement paste particles. Hence, this study aims to produce the cement mortars using the upgraded recycled concrete aggregates (sand g [...]

by Annie Keleher  , Paul Dargusch  and Genia Hill

Received: 13 January 2022;  Published: 15 April 2022;  doi: 10.21926/aeer.2202013

With scientific consensus on climate change and growing public concern, firms are recognising the multiple risks associated with inaction on their Greenhouse Gas (GHG) emissions. The Information and Communications Technology (ICT) and Entertainment & Media (E&M) sectors provide essential communications services, that are foundational for much of the modern world's social and economic systems. The ICT sector has already demonstrated success in innovations that enable emissions reductions. At the same tim [...]

by Joseph V. Pergolizzi  , Jo Ann LeQuang  , Peter Magnusson  and Giustino Varrassi

Received: 11 April 2021;  Published: 12 July 2021;  doi: 10.21926/obm.icm.2103021

Traditional, complementary, and integrative medicine (TCIM) approaches to COVID-19 represent a paradigm shift from Western medicine, in that TCIM emphasizes prevention, encouraging wellness, and supporting health and recovery. A wide range of TCIM approaches exist: whole medical systems (such as traditional Chinese medicine), mind-body approaches, biological therapies, body-based treatments, and energy therapies. TCIM is used to help people resist infection, but people with moderate to severe COVID-19 symptoms ofte [...]

by Selin Galatalı  , Damla Ekin Özkaya  , Taner Mercan  and Ergun Kaya

Received: 27 July 2023;  Published: 19 October 2023;  doi: 10.21926/obm.genet.2304198

In the face of rapid population growth worldwide, humanity's need for plant and animal products is increasing. In this regard, the organizations in charge of production make production and consumption forecasts for the future and try to accelerate the work aimed at increasing production. There are various ways of increasing production. The first of these is the improvement of cultivation techniques, the expansion of irrigated agricultural areas, and the effective control of diseases and pests. The second is to find [...]

by Maria Victoria Tejada-Simon  and Sara Lodhi

Received: 14 November 2021;  Published: 04 March 2022;  doi: 10.21926/obm.icm.2201009

Mindfulness is a form of meditation that can be defined as one’s ability to be present to the surroundings and environment, and not overreact to what is happening around us. With the recent pandemic still affecting the world, more studies have recently become known describing the suitability of mindfulness to prevent and manage mental health. This fact alone offers grounds for mindfulness practices to be added to any stressful environment, including Institutions of higher education and the workforce. Even more, min [...]

by XinRan Quan  and Marica Bakovic

Received: 21 December 2020;  Published: 21 July 2021;  doi: 10.21926/obm.geriatr.2103176

Neurodegenerative diseases (NDs) are a diverse group of neuropathological diseases that are currently incurable due to the irreversible neuronal loss. At the present rate of the world population growth, it is projected that the number of ND cases will double by the year of 2050. With treatments only available for symptom management and relief, disease prevention may yield significant benefits. Recently, there had been association drawn between the disruption of phospholipid (PL) homeostasis and the progression of N [...]

by Aminata Bicego  , Pauline Delmal  , Didier Ledoux  , Marie-Elisabeth Faymonville  , Benoît Maertens de Noordhout  , Alfredo Cerasoli  , Héléna Cassol  , Olivia Gosseries  and Audrey Vanhaudenhuyse

Received: 29 June 2022;  Published: 09 September 2022;  doi: 10.21926/obm.icm.2203040

Phantom limb pain occurs in more than half of the people who have undergone an amputation. Hypnosis can alleviate pain effectively in experimental, procedural, and chronic pain. Thus, in this multiple-case study, we determined whether hypnosis might be a successful complementary approach to help patients with phantom limb pain in alleviating their pain quality (i.e., sensitive and affective), intensity, fatigue, and emotional distress (i.e., anxiety and depression). Seven patients experiencing phantom limb pain wer [...]