by Nazrien M.D Nazrien  , Novitri  , Tertianto Prabowo  and Farida Arisanti

Received: 14 September 2023;  Published: 17 February 2024;  doi: 10.21926/obm.neurobiol.2401211

Balance is the ability to move and/or preserve a particular position while not falling under external force. Human balance is a complex process of integration and coordination of the sensory, motor, and biomechanical components, which is influenced by intrinsic and exogenous factors. One inherent factor that is hypothesized to have an impact on balance is cognition. However, studies about cognition's role in balance control are still limited, and study literature is needed to gain a better understanding. Cognition [...]

by Yuqi Tang  , Xuejun Qian  , Darrin J. Lee  , Qifa Zhou  and Junjie Yao

Received: 24 October 2019;  Published: 30 April 2020;  doi: 10.21926/obm.neurobiol.2002056

Alzheimer’s disease (AD) causes severe cognitive dysfunction and has long been studied for the underlining physiological and pathological mechanisms. Several biomedical imaging modalities have been applied, including MRI, PET, and high-resolution optical microscopy, for research purposes. However, there is still a strong need for imaging tools that can provide high spatiotemporal resolutions with relatively deep penetration to enhance our understanding of AD pathology and monitor treatment progress in fundamental r [...]

by Carsten Unglaub  , Johannes Thiessen  and Andreas Jess

Received: 27 September 2022;  Published: 03 January 2023;  doi: 10.21926/cr.2301001

Fischer-Tropsch reactors operated in a steady state suffer from a low pore effectiveness factor and a high methane selectivity caused by internal mass transfer limitations due to the accumulation of long-chain hydrocarbons inside the catalyst pores. Therefore, an alternating process switching between Fischer-Tropsch synthesis (FTS) and drainage of the pores by hydrogenolysis is proposed. The periodical cracking of the accumulated waxes within the (partially) filled pores, realized by a switch from syngas (H2, CO) t [...]

by Ryosuke Oochi  , Kengo Aoyama  and Akira Ueda

Received: 27 November 2019;  Published: 12 February 2020;  doi: 10.21926/jept.2001002

In order to achieve advancement in zero-emission geothermal power generation for fixing the CO2 in the geothermal fluids to the carbonate minerals after binary power generation and reinjection of the fluid into the reservoir, batch-type experiments and geochemical simulations of CO2-andesitic pyroclastic rock interaction (tuff from Oku-Aizu geothermal area) were performed at 150 °C with and without CO2 gas for 15 days. Despite the low Ca content (0.9% wt.%) in the rock, the Ca2+ concentrations in the solutions [...]

by Natalia V. Kovaleva  and Philip D. Cotter

Received: 02 May 2022;  Published: 05 September 2022;  doi: 10.21926/obm.genet.2203162

Mosaicism for trisomy of chromosome 14 (T14) is a very rare chromosomal disease in liveborn patients. Since the 1970s, when the first patients with mosaicism for T14 were reported, a number of studies on the clinical manifestations of this abnormality have been published. No information on epidemiological parameters was known except for the rarity of the disease and its predominance among female carriers. This was the first systematic review of published cases of mosaic T14 that addressed some epidemiological aspec [...]

by Chenchang Li  , Jianqiang Hu  , Jie Yu  , Jieci Xue  , Runze Yang  , Yijie Fu  and Bo Sun

Received: 23 April 2021;  Published: 15 July 2021;  doi: 10.21926/jept.2103033

Due to the uncertainty and volatility of wind speed, its natural output power also exhibits strong volatility. In order to avoid the negative effects of the excessive fluctuation of the output power of wind turbines in the wind farm and the power grid, it is very important to accurately predict and reasonably plan and control the output power of the wind farm. Model predictive control (MPC) is a type of advanced control method that can deal with a multi-input multi-output nonlinear system. Compared to the tradition [...]

by Ken-ichi Takayama

Received: 26 May 2018;  Published: 02 November 2018;  doi: 10.21926/obm.genet.1804047

Prostate cancer is the most common cancer among men in the world. Androgen receptor (AR), acting as a nuclear receptor, facilitates ligand-dependent transcriptional activation in the nucleus. Androgen deprivation therapy (ADT) is used for the treatment of advanced prostate cancer because androgen and AR signaling drive prostate tumor growth and anti-apoptotic function. Resistance to ADT in most tumors develops quickly; thus, AR continues to be active in relapsed tumors called castration-resistant prostate cancer (C [...]

by Mary P Galea  , Natasha van Zyl  and Aurora Messina

Received: 02 October 2020;  Published: 29 December 2020;  doi: 10.21926/obm.neurobiol.2004075

Spinal cord injury (SCI) leads to an immediate loss of sensory and motor function below the level of injury mostly affecting people in the prime of life. In addition to the primary injury there is accumulating neurophysiological and histological evidence of dysfunction in the peripheral nerves, not related to direct damage from the primary injury, which exacerbates muscle wasting, and contributes to further functional loss and poor recovery. Among the potential contributing factors are systemic inflammation, and mo [...]

by Khaled Hassan  , Ian Sims  , Murray Reid  , Alex Smith  and Mohammed Al-Kuwari

Received: 18 April 2021;  Published: 26 September 2021;  doi: 10.21926/rpm.2103038

Wadi gravel is a local aggregate in Qatar that could contribute to enhanced sustainability by replacing expensive imported gabbro. The material needs to be processed before use to reduce sulfate content to acceptable levels. The paper presents the performance assessment of three full-scale buildings, variously made with 50% and 100% Wadi gravel and conventional gabbro concretes. Site monitoring up to four years in service demonstrated the strength development with age and resistance to the aggressive exposure condi [...]

by Michele Bisceglia  , Stefano Pizzolitto  , Tullio Parracino  , Giovanna De Maglio  , Elena Minenna  , Serena D’Agostini  and Carlos A. Galliani

Received: 07 October 2018;  Published: 14 November 2018;  doi: 10.21926/obm.neurobiol.1804016

Thyroid transcription factor 1 (TTF-1) is a nuclear polypeptide and a tissue-restricted member of the homeobox protein family that, when attached to DNA, plays a crucial role in regulating the expression of select genes during early embryonic development of the thyroid, lung, and brain. As often happens, the initial enthusiasm for the diagnostic value of TTF-1 as a selective immunohistochemical marker of lung and thyroid tumors began to dwindle, due to its detection in tumors arising from other organs. TTF-1-expres [...]

by Fabien Leurent

Received: 10 March 2022;  Published: 18 July 2022;  doi: 10.21926/jept.2203025

The carbon footprint of motorized transport modes per unit length traveled encompasses the unit share of the vehicle lifetime emissions, that of the transport infrastructure, and those of the motor energy, considered both from “well to tank” and from “tank to wheel”. In the active modes of transport, i.e., walking and cycling, the counterpart of motor energy is human energy, which is associated with two kinds of carbon flows: the carbon footprint of food intake, – which we call the Food to Body component – and the [...]

by Maggie MacKinnon  , Maibritt Pedersen Zari  and Daniel K. Brown

Received: 13 August 2021;  Published: 09 November 2021;  doi: 10.21926/aeer.2104029

The practice of reconciliation ecology in urban environments relies heavily on urban green space as the primary source of vegetated habitat in cities. However, most cities lack the quantity, connectivity, and accessibility of green space needed to provide essential ecosystem services for the health, well-being, and resilience of human and non-human species. In reaction to urban densification and the increasing frequency and severity of climate change impacts, this study argues that architecture could strategically [...]

by Enrico Facco

Received: 04 February 2020;  Published: 08 July 2020;  doi: 10.21926/obm.icm.2003032

The topic of resilience is of paramount importance. Although the term resilience was coined in the fields of physics and engineering, its use has spread to the fields of social sciences, biology, psychology, and psychiatry, as well as to the industry. Moreover, the term is now endowed with a wide range of meanings. The topic of resilience plays a central role in all critical life events. It is of paramount importance in medicine as well as in psychology and psychotherapy, where it is involved in both psychiatric di [...]

by Igor Val Danilov  and Sandra Mihailova

Received: 02 October 2021;  Published: 29 December 2021;  doi: 10.21926/obm.neurobiol.2104113

The present interdisciplinary study discusses the physical foundations of the neurobiological processes occurring during social interaction. The review of the literature establishes the difference between Intentionality and Intention, thereby proposing the theoretical basis of Shared Intentionality in humans. According to the present study, Shared Intentionality in humans (Goal-directed coherence of biological systems), which is the ability among social organisms to instantly select just one stimulus for the entire [...]

by Mitsuko Hirosawa  , Koji Hayakawa  , Kunio Shiota  and Satoshi Tanaka

Received: 05 July 2018;  Published: 17 September 2018;  doi: 10.21926/obm.genet.1803036

Histone modifications play an important role in the control of DNA-based processes by altering the structure and function of chromatin. O-linked N-acetylglucosamine (O-GlcNAc) modification is a form of post-translational modification of proteins that affects the serine (Ser)/threonine (Thr) residues. This process is controlled by a single pair of enzymes, i.e. O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). Recent evidence indicates the existence of O-GlcNAc modification of histones, with 16 histone O-GlcNAc site [...]

by Ladislaus Alexander Bányai  and Mircea Bundaru

Received: 21 October 2022;  Published: 08 December 2022;  doi: 10.21926/rpm.2204027

We describe here the coherent formulation of electromagnetism in the non-relativistic quantum-mechanical many-body theory of interacting charged particles. We use the mathematical frame of the field theory and its quantization in the spirit of the quantum electrodynamics (QED). This is necessary because a manifold of misinterpretations emerged especially regarding the magnetic field and gauge invariance. The situation was determined by the historical development of quantum mechanics, starting from the Schrödinger e [...]

by Paul D. Loprinzi

Received: 07 February 2019;  Published: 21 March 2019;  doi: 10.21926/obm.icm.1901018

The objective of this brief systematic review was to examine the effects of aquatic exercise on cognitive function. Studies were identified using electronic databases, including PubMed, PsychInfo, Sports Discus and Google Scholar. In total, 13 articles met the inclusionary criteria. Among the 13 studies, all 13 demonstrated beneficial cognitive effects from exercise. This included chronic aquatic exercise-induced improvements in global cognition, executive function, attention, learning and memory, cognitively-relat [...]

by Rakesh Chandra Nainwal  , Premchand Chaurasiya  , Arun Kumar  , Mohan Singh  , Devendra Singh  and Shri Krishna Tewari

Received: 14 March 2024;  Published: 12 June 2024;  doi: 10.21926/aeer.2402015

Soil salinization is a significantconstraint affecting the productivity of agricultural land worldwide. This led to the abandoning of the production of farmcrops on colossalland. Soil salinity inversely affects seed germination and plant growth and influences the plant’s biological activities like photosynthesis, respiration, plant metabolism, enzymatic activities, hormone regulation, etc. Therefore, efforts are being made to bring the saline soil under cultivation by improving itthrough a proper drainage sys [...]

by Giuseppe Cocco  and Philipp R. Amiet

Received: 16 January 2021;  Published: 28 July 2021;  doi: 10.21926/obm.geriatr.2103178

Atrial fibrillation is very common in most old patients who need an adapted therapy due to their comorbidities. Before initiating an antiarrhythmic therapy, possible adverse effects, especially iatrogenic proarrhythmia, and extracardiac side-effects, must be considered. In geriatric patients with atrial fibrillation, heart rate control is the most frequent therapy. Oral anticoagulation plays a vital role in the therapy, but anticoagulation in old patients, who had a bleeding or stroke event, is challenging. Availab [...]

by Nadia El Kadmiri

Received: 16 August 2023;  Published: 07 August 2024;  doi: 10.21926/obm.neurobiol.2403238

The use of immunotherapy as a therapeutic approach to Alzheimer's Disease (AD) is gaining rapid interest, with the primary goal of targeting abnormalities that impact neuronal viability through specific antibodies. Currently, clinical strategies focus intensively on targeting the two main pathologies associated with AD, beta-amyloid (Ab) and tau. This review examines ongoing research in the realm of tau immunotherapy, including clinical trials that demonstrate promising potential for halting AD progression. Several [...]

by Shruthi Kodad  , Waleed Sabry  , Assem Elsayed  , Hadi Goubran  and Mohamed Elemary

Received: 25 June 2019;  Published: 26 August 2019;  doi: 10.21926/obm.transplant.1903081

Hematopoietic stem cell transplant (HSCT) recipients are at an increased risk of bacterial, viral, fungal and parasitic infections. Past exposures to infections, the degree of immunosuppression, prolonged neutropenia and presence of graft versus host disease (GVHD) are some of the factors which make HSCT recipients more susceptible to infections. Viral infections have emerged as a major challenge causing high morbidity and mortality in stem cell transplant recipients. Myeloablative conditioning regimens and GVHD pr [...]

by Siamak Shirani Bidabadi  , Parisa Sharifi  and S. Mohan Jain

Received: 09 June 2021;  Published: 15 September 2021;  doi: 10.21926/obm.genet.2103137

Plant breeding programs have used conventional breeding methods, such as hybridization, induced mutations, and other methods to manipulate the plant genome within the species' natural genetic boundaries to improve crop varieties. However, repeatedly using conventional breeding methods might lead to the erosion of the gene reservoir, thereby rendering crops vulnerable to environmental stresses and hampering future progress in crop production, food and nutritional security, and socio-economic benefits. Integrating in [...]

by Jozélio Freire de Carvalho  and Aaron Lerner

Received: 20 June 2024;  Published: 12 October 2024;  doi: 10.21926/obm.icm.2404058

To systematically review the literature for cases using homeopathy in which complete healing was observed. Scielo, Pubmed, CINAHL, and Embase databases were systematically screened for case reports and series of patients successfully cured by homeopathy between 1966 and August 2022. Language limitation was not used. Forty-nine articles, comprising 191 patients, were depicted. Most of them had dermatological conditions (12 papers, 71 patients), followed by infectious (7 papers, 31 patients), neuropsychiatric (10 pub [...]

by Kamalakanta Sahoo  , Richard Bergman  and Poonam Khatri

Received: 24 August 2021;  Published: 21 December 2021;  doi: 10.21926/rpm.2104049

According to the United Nations Environment Programme (UNEP), the construction and operation of buildings accounted for nearly 38% of total global energy-related CO2 emissions in 2019. The construction sector has been striving to use more low-carbon footprint building products to mitigate climate change and enhance environmentally preferable purchasing. Over the last several decades, there has been substantial growth in engineered wood products for the construction industry. To assess these products used in constru [...]

by Zakkoyya H. Lewis  , Ryan N. Harrison  , Brian D. Clocksin  , Alexandra T. Auslander  and Lara Killick

Received: 05 July 2023;  Published: 12 September 2023;  doi: 10.21926/rpn.2303016

Within the US, people are experiencing longer life expectancy, yet these extended lifespans have not necessarily translated into years living in good health. Musculoskeletal degenerative diseases are particularly prevalent amongst older adults. Research shows that regular resistance exercise carries preventive health benefits to combat these conditions. This study evaluated the impact of an innovative hand-held device (OYO) on the physical function of older adults compared to a traditional chair fitness program (CF [...]