by David W. Scharp  , Jayagowri Arulmoli  , Kelly Morgan  , Hannah Sunshine  and Ergeng Hao

Received: 15 October 2018;  Published: 26 February 2019;  doi: 10.21926/obm.transplant.1901052

Background: This presentation of a six-year study processing human islets for research and transplantation includes a review of multi-center transplant studies identifying key variables critical for successful islet processing and defines standardized processing procedures required to provide highly purified, functional Human Islets. Methods: Human islet processing methods are defined in detail with pancreas retrieval, shipping, trimming for processing, collagenase distension, controlled digestion by digestion/filt [...]

by Mubashir Zafar

Received: 13 March 2024;  Published: 24 May 2024;  doi: 10.21926/obm.neurobiol.2402225

The increasing prevalence of mental health issues among university students has become a growing concern globally. This review explores the potential of Artificial Intelligence (AI) integrated with principles of behaviour therapy to address mental health challenges among university students. The paper examines how AI technologies, including chatbots, virtual reality, and machine learning algorithms, can be harnessed to provide accessible, personalized, and effective mental health interventions. Furthermore, it disc [...]

by Athalie Redwood-Mills  , Taea Scott  , Mhairi Morris  and Jennifer Wilson

Received: 01 June 2024;  Published: 08 November 2024;  doi: 10.21926/obm.icm.2404066

Chronic diseases, responsible for 74% of global mortality, impose a substantial health burden. This study investigates the perceived effects of CrossFit, a form of functional training, on medication use in the UK population. The research aims to provide insights into how CrossFit might relate to medical interventions for individuals with long-term health conditions. The study, encompassing 1,211 UK residents (over 18yrs.) recruited via CrossFit Affiliates, involved a 14-question online survey covering information p [...]

by Foad Haeri  , Deepak Tapriyal  , Christopher Matranga  , Dustin Crandall  and Angela Goodman

Received: 05 September 2021;  Published: 05 November 2021;  doi: 10.21926/jept.2104046

Contact angles were measured for CO2-brine interactions on 20 different rocks that represent the properties of various CO2 storage depositional environments to characterize the wettability during geologic carbon storage. Three different CO2 phases (gaseous, liquid, and supercritical) were considered to investigate the effect of pressure and temperature. Bubbles were studied in two groups of larger and smaller than 500 μm, the latter being more relevant to pore scale. Variation was observed among contact angle measu [...]

by Michael Fossel

Received: 11 December 2016;  Published: 06 January 2017;  doi: 10.21926/obm.geriatr.1701001

Geriatrics, and much of clinical medicine, is on the verge of a profound transformational shift. Until now, there has been a sharp conceptual divide between diseases which can be readily and effectively treated, and diseases which we have thought to be beyond clinical intervention. In the first disease category, are many of the most common infections that respond to antibiotics and immunizations. We have made dramatic changes in the demographics and the mortality of many such treatable diseases. At the other extrem [...]

by Morgan J. Minyo  and Katherine S. Judge

Received: 30 July 2019;  Published: 07 February 2020;  doi: 10.21926/obm.geriatr.2001104

Through the assessment of previous and current literature on the behaviors experienced by persons with dementia, this review discusses the terminology, conceptual models, measurement techniques, and non-pharmacological interventions employed within behavioral research. Additionally, this review considers the illness experience and the need for more research using self-report methodology with persons with dementia in order to address the current gaps within the behaviour literature. With three main objectives, this [...]

by Pierpaolo Di Cocco  , Alberto Fratti  , Kerim B. Kaylan  , Ivo G. Tzvetanov  and Enrico Benedetti

Received: 22 August 2020;  Published: 28 September 2020;  doi: 10.21926/obm.transplant.2003119

This article reviews the current treatment strategies of antibody-mediated rejection in kidney transplantation, which is increasingly recognized as the leading immunological cause of graft failure. The pathophysiologic complexity of this condition poses significant challenges for its treatment; however, progress toward advancing our understanding of its pathogenesis and diagnosis will allow for identification of new therapeutic targets. Emphasis is also given to prevention, which is mainly based on careful assessme [...]

by In Lam  , Irina Gutman  , Ashley Feist  and Mark Mariski

Received: 10 March 2017;  Published: 22 June 2017;  doi: 10.21926/obm.transplant.1701003

After lung transplant, infection is a leading contributor to morbidity and mortality, and hypogammaglobulinemia (HGG) may be an important risk factor for many of these infections. Some reports suggest that HGG not only increases the risk of various infections, but also worsens survival. The incidence of HGG has been shown to increase after lung transplant, and may be as high as 70%. In order to mitigate this risk, intravenous immunoglobulin G (IVIG) replacement for the treatment of HGG has been utilized. However, t [...]

by Nazrien M.D Nazrien  , Novitri  , Tertianto Prabowo  and Farida Arisanti

Received: 14 September 2023;  Published: 17 February 2024;  doi: 10.21926/obm.neurobiol.2401211

Balance is the ability to move and/or preserve a particular position while not falling under external force. Human balance is a complex process of integration and coordination of the sensory, motor, and biomechanical components, which is influenced by intrinsic and exogenous factors. One inherent factor that is hypothesized to have an impact on balance is cognition. However, studies about cognition's role in balance control are still limited, and study literature is needed to gain a better understanding. Cognition [...]

by Joana Sousa

Received: 05 October 2023;  Published: 29 February 2024;  doi: 10.21926/aeer.2401008

The consistent associations between dampness and health-related problems, such as allergies and asthma symptoms, explain the growing scientific interest in assessing housing characteristics. Due to a growing interest in the built environment, the present study performed a systematic review to investigate the prevalence of dampness related to specific building characteristics. The built environment is gaining significance in population well-being due to the substantial time spent indoors. This aspect is especially n [...]

by Bo-Cai Gao  and Rong-Rong Li

Received: 26 April 2021;  Published: 05 July 2021;  doi: 10.21926/aeer.2103017

Passive high spatial resolution hyperspectral and multispectral imaging systems in the solar spectral region from aircraft and satellite platforms are being increasingly used for remote sensing of coastal waters and inland lakes. However, the remotely sensed data are often contaminated by the specular reflection of solar radiation at the air/water interface. Thus, the effects of sunglint need to be corrected. The purpose of sunglint correction is to remove the undesired specular reflected portion of radiance that d [...]

by Najam A. Sharif

Received: 24 January 2022;  Published: 22 March 2022;  doi: 10.21926/obm.neurobiol.2201116

Glaucomatous optic neuropathy (GON) associated with different forms of glaucoma and chronic ocular hypertension (cOHT) is characterized by progressive loss of retinal ganglion cells and their axons in the optic nerves that project to the brain to transmit visual information. The resultant thinning of the optic nerves cause loss of peripheral vision, which if not halted or slowed, can lead to irreversible blindness. Whilst the precise triggering insult(s) for the primary open angle glaucoma (POAG), the most prevalen [...]

by Cenk Temizel  , Hakki Aydin  , F. Bahar Hosgor  , Cengiz Yegin  and C. Shah Kabir

Received: 25 September 2022;  Published: 28 January 2023;  doi: 10.21926/jept.2301004

In recent years, the oil and gas sector has been moving towards green production methods to achieve net-zero emission goals. Governments and corporations have started large-scale initiatives to deploy advanced technologies to reduce carbon footprints and prevent global warming. Herein, we have explored the emerging techniques and methods used in reducing the effects of gas emissions in the oil and gas industry. The transition process from hydrocarbons to renewable energy resources, including solar thermal applicati [...]

by Anita Verma  and Anil Dhawan

Received: 14 February 2020;  Published: 11 May 2020;  doi: 10.21926/obm.transplant.2002108

The infectious complications before and after liver transplant (LT) are affected by the severity of liver disease and immunosuppression intensity after transplantation. Both cirrhosis and immunosuppression contribute to dysfunction of defensive mechanisms of the host. When a patient is evaluated for transplantation, the opportunity arises to assess the individual’s risk for infection and how one may modify those risks through prophylactic and therapeutic strategies. Pretransplant infectious disease evaluation focus [...]

by Fabien Leurent

Received: 10 March 2022;  Published: 18 July 2022;  doi: 10.21926/jept.2203025

The carbon footprint of motorized transport modes per unit length traveled encompasses the unit share of the vehicle lifetime emissions, that of the transport infrastructure, and those of the motor energy, considered both from “well to tank” and from “tank to wheel”. In the active modes of transport, i.e., walking and cycling, the counterpart of motor energy is human energy, which is associated with two kinds of carbon flows: the carbon footprint of food intake, – which we call the Food to Body component – and the [...]

by Allison B. Ventura  , Barbara I. Kissam  , Kandise Chrestensen  , Ian Tfirn  , Jennifer Brailsford  and Lourdes P. Dale

Received: 27 November 2022;  Published: 24 May 2023;  doi: 10.21926/obm.icm.2302022

Mindful education (ME) in schools can address student well-being and stressors, as well as improve the overall school environment. Implementing a whole-school mindfulness curriculum can be challenging, especially when serving students in both general education and emotional behavioral disorder (EBD) settings. We investigated the feasibility, implementation, and benefits of a whole-school mindfulness curriculum (MindUP) in an urban elementary school. This study is unique in that it investigated how to implement mind [...]

by Ladislaus Alexander Bányai  and Mircea Bundaru

Received: 21 October 2022;  Published: 08 December 2022;  doi: 10.21926/rpm.2204027

We describe here the coherent formulation of electromagnetism in the non-relativistic quantum-mechanical many-body theory of interacting charged particles. We use the mathematical frame of the field theory and its quantization in the spirit of the quantum electrodynamics (QED). This is necessary because a manifold of misinterpretations emerged especially regarding the magnetic field and gauge invariance. The situation was determined by the historical development of quantum mechanics, starting from the Schrödinger e [...]

by Alhayat Getu Temesgen  , Ömer Fırat Turşucular  and Elif Dicle Turşucular

Received: 12 December 2023;  Published: 15 March 2024;  doi: 10.21926/rpm.2401008

This mini-compilation study included the chemical structure, mechanical, thermal, and dimensional properties of silk fiber, its production process, pre-treatment, and biomedical applications from various experimental studies, which are compiled and summarized. The silk fiber should have a degumming process before using biomedical applications. The 25% concentration for Na2CO3 in ethanol solution (80%) as a coagulant chemical with a salt such as LiB2 (9 M) at a temperature of 98°C for 45 minutes at pH between 6 [...]

by Francesco Sivelli  , Elio Rossi  , Sonia Baccetti  , Mariella Di Stefano  , Eugenia Gallo  and Fabio Firenzuoli

Received: 27 September 2018;  Published: 18 October 2019;  doi: 10.21926/obm.icm.1904060

Phytotherapy, which is defined as the use of titrated herbal extracts in clinical practice, has been receiving increasing interest in the scientific community recently. In the present report, information regarding the most important mechanisms underlying the drug-drug interactions (DDI) and herb-drug interactions (HDI) has been discussed briefly. Furthermore, the best known and relevant interactions of Ginkgo biloba, Citrus paradisi (Grapefruit Juice), Silybum marianum (Milk Thistle), Hypericum perforatum (St. John [...]

by Alexander Manevich  , Simon Shimshon Rubin  , Rachel Ben-Hayun  , Judith Aharon-Peretz  and Michael Katz

Received: 07 September 2020;  Published: 12 March 2021;  doi: 10.21926/obm.geriatr.2101160

Caregiving for a loved one suffering from cognitive decline involves coping with many challenges and losses. This experience increases the risk of worsening the physical and mental health of the caregiver and has been the subject of a substantial number of studies focusing on the stress and burden of the primary caretaker. Theory and research on the grief reactions experienced by the family members, however, continues to lag in terms of the attention given to the behavioral and psychological burden of caregivers. T [...]

by Jun Kohyama

Received: 21 February 2019;  Published: 22 July 2019;  doi: 10.21926/obm.neurobiol.1903034

Background: Several recommendations on optimum sleep duration have been published for adolescents to secure a healthy life. This study aimed to compare the sleep duration of middle and high school pupils in Japan with the recommended values and determined the factors associated with the duration of sleep among them. Methods: A total of 1766 completed questionnaires were obtained from grades 7 to 12 pupils in Japan. The questionnaire addressed the following points: sleeping, eating, defecation, physical activity, sc [...]

by Riccardo Misto

Received: 19 November 2020;  Published: 24 May 2021;  doi: 10.21926/obm.icm.2102019

Using musical scales in a therapeutic key is one of the fundamental music therapy techniques of the Yoga of Sound (Nāda Yoga). The practice consists of singing particular sound formulas (scales), which are devised on a logical mathematical basis formed by specific musical intervals. These scales can bring to the surface, in a clear (objective), recognizable, and predictable way, psycho-emotional states and transform the blocked emotional energies. These blocked emotional energies are caused by repeated emotional st [...]

by Temitope Akinjogbin  , Jacob Parnell  and Maria C. Duggan

Received: 05 May 2020;  Published: 13 July 2020;  doi: 10.21926/obm.geriatr.2003128

Delirium is an acute change in mental status with key features of inattention and disorganized thinking. It is particularly common in older adults, with multiple and varied causes. Delirium increases the risk of morbidity, mortality, institutionalization, and healthcare costs; however, it is often missed because it is difficult to recognize without the use of a validated screening tool. The Age-Friendly Health Systems (AFHS) initiative highlights the need for implementation of a delirium monitoring program in hospi [...]

by Karine Sénécal  , Brigid Unim  and Bartha Maria Knoppers

Received: 19 October 2017;  Published: 14 August 2018;  doi: 10.21926/obm.genet.1803027

The benefits of neonatal screening programs are undeniable: children’s lives are saved, and disease burden and morbidity alleviated. Without a doubt, « classical » neonatal screening programs are in the best interests of newborns. Indeed, those screening programs are recognized among the ten most important public health achievements. However, newborn screening programs raise ethical, legal and social challenges. For example, which criteria should govern whether or not to include a disease in the list of screened co [...]

by Ana Monteagudo-Sánchez  , Marta Sánchez-Delgado  , Sonia Guara Ciurana  , Jose Medrano  , Maria Eugenia Poo-Llanillo  , Miho Ishida  , Gudrun E. Moore  , Isabel Iglesias-Platas  , Carlos Simón  and David Monk

Received: 29 May 2018;  Published: 29 July 2018;  doi: 10.21926/obm.genet.1803026

Background: Symmetrical DNA methylation profiles of autosomal genes are associated with equal expression by both alleles. Genes with an allelic imbalance or monoallelic expression are associated with discrete intervals of allele-specific methylation (ASM), as highlighted by genomic imprinting, X-chromosome inactivation and genotype-driven ASM. However, a more complex pattern has been described in which random monoallelic methylation provides cells with a unique mechanism for modulating allelic dosage. Methods: We c [...]