by Robert J Emanuel

Received: 09 January 2019;  Published: 21 March 2019;  doi: 10.21926/obm.geriatr.1901040

The amount of patients who suffer with dementia is set to rise with an ageing population. As well as living longer, patients will be retaining their natural teeth into their later life and will be less reliant on dentures. From both the current evidence available in the literature, and anecdotally from clinicians experienced in treating patients with dementia, it can be concluded that on balance, patients with dementia appear to be at a greater risk from dental caries (dental decay). However, more research in this [...]

by Manuel Legree  , Jocelyn Sabatier  , Fabrice Mauvy  , Abdel Salam Awad  , Matthieu Faessel  , Frederic Bos  and Jean-Louis Bobet

Received: 04 March 2020;  Published: 28 April 2020;  doi: 10.21926/jept.2002004

This paper focuses on hydrogen production for green mobility applications (other applications are currently under investigation). Firstly, a brief state of the art of hydrogen generation by hydrolysis with magnesium is shown. The hydrolysis performance of Magnesium powder ball–milled along with different additives (graphite and transition metals TM = Ni, Fe, and Al) is taken for comparison. The best performance was observed with Mg–10 wt.% g mixtures (95% of theoretical hydrogen generation yield in about 3 min). An [...]

by Jennie Cao  , Valentina L Kouznetsova  and Igor F Tsigelny

Received: 30 January 2019;  Published: 01 April 2019;  doi: 10.21926/obm.genet.1902071

Cancer is the leading cause of death in dogs, and 50 percent of dogs over the age of 10 develop cancer at some point. The most common cancers in dogs include lymphoma, mast cell tumors, osteosarcoma, mammary gland tumors, and melanoma, and many of them share marked similarities with their human counterparts. Although canines are afflicted with many of the same types of cancers as humans, the genetic basis behind these cancers are not as well understood. Thus, the aim of this study is to elucidate some of the molecu [...]

by Gunnel Berry

Received: 13 April 2018;  Published: 25 February 2019;  doi: 10.21926/obm.icm.1901012

Chronic pain is notoriously multifactorial, multifaceted and difficult to manage. Twenty per cent of reported whiplash-injured persons go on to develop a Whiplash Associated Disorder (WAD) where persistent pain becomes chronic with no prospect of change [1]. Paucity of effective therapies to address the effect of WAD enforces new approaches. This case report, with a patient’s perspective, illustrates a novel therapy, Adapted Reflextherapy (AdRx), which is akin to reflexology and has been used, developed and revised [...]

by Mohamed Abutineh  , Nicholas Pizzo  , Nicholas Nifakos  , Xiao-Lu Jin  , John M Harlin  and Xing-Hai Zhang

Received: 26 October 2020;  Published: 18 February 2021;  doi: 10.21926/obm.genet.2101124

Citrus is an important group of globally produced fruit crops, holding great economic, cultural, and health value. Belonging to the Rutacaeae family, the genus Citrus includes some of the most iconic and widely appreciated variants of fruits such as the orange, lemon, lime, grapefruit, and tangerine. The spread of various diseases threatens the worldwide production of citrus fruit crops. Diseases such as Asiatic citrus canker, citrus tristeza virus, citrus leprosis, and especially citrus greening disease (also know [...]

by Michelle Szucs  , Miguel Angulo  , Carlos Costa  and Mª Carmen Márquez

Received: 12 May 2021;  Published: 08 November 2021;  doi: 10.21926/rpm.2104045

Five different commercial proteases (Alcalase 2.4L, Flavourzyme 1000L, Neutrase, Protamex, and PTN) were evaluated for the simultaneous recovery of protein and lipids through hydrolysis. The hydrolysis reaction was monitored using the pH-stat procedure, in which samples were collected after 240 min of hydrolysis using each enzyme. The samples were analyzed for the degree of hydrolysis, protein hydrolysate, collagen, lipids, and fatty acids. A clear relationship was observed between the degree of hydrolysis and the [...]

by Sara B Taylor  , Kristy Arbon  and Faith Reynolds

Received: 27 October 2020;  Published: 31 March 2021;  doi: 10.21926/obm.icm.2101011

Somatic Self-Compassion® training is a newly developed trauma-informed self-compassion training that was designed to combine interoception and sensory modulation in order to teach individuals to more effectively cope with current and past stress. Thirty-two non-clinical adults across five cohorts participated in this pre-post design feasibility study. Participation in Somatic Self-Compassion® Online resulted in significant reductions in perceived stress, internalized shame, and bodily shame and significant improvem [...]

by Hans Rhode  , Thomas Liehr  , Nadezda Kosyakova  , Martina Rinčić  and Shaymaa S. Hussein Azawi

Received: 30 July 2018;  Published: 19 September 2018;  doi: 10.21926/obm.genet.1803037

(1) Background: Colorectal cancer (CRC) is the third most common cancer in human and the fourth leading cause of adult man’s death. Murine tumor cell lines have been established as a model system for CRC, but their cytogenetic properties have so far been only poorly understood. (2) Methods: The two murine colon tumor cell lines CMT-93 and CT26 (also called CT26.WT, CT-26 or CT-26 WT) were investigated in this study by molecular cytogenetic methods, i.e. by multicolor-fluorescence in situ hybridization (mFISH), muri [...]

by Elizabeth Orsega-Smith  , Stephen Goodwin  , Melissa Ziegler  , Katie Greenawalt  , Jennie Turner  and Erica Rathie

Received: 31 October 2018;  Published: 10 January 2019;  doi: 10.21926/obm.geriatr.1901029

Background: Research has shown that positive psychology interventions can enhance subjective well-being and reduce depression. However, the efficacy of these programs with older adult populations has been minimally studied. The present study studied the short and long term impact of an intervention enhancing happiness and overall mental well-being in older adults. Methods: The Art of Happiness is an 8-week program conducted at 2 senior centers in the state of Delaware. Each 90-minute class examined a different topi [...]

by Giuseppe De Benedittis

Received: 18 February 2020;  Published: 24 April 2020;  doi: 10.21926/obm.icm.2002023

There is increasing evidence demonstrating that hypnosis could be effective in the down-modulation of pain sensation in both acute and chronic pain states. In the neurophysiological context, recent evidence has deciphered, to a certain extent, the mystery of pain relief upon hypnosis. It is probable that hypnotic suggestions of analgesia are able to modulate pain processing at multiple levels and sites within the central nervous system (CNS). At the peripheral level, hypnosis may modulate the nociceptive input thro [...]

by Jana Wurz  , Nicolette Nadene Houreld  and Janice Pellow

Received: 12 April 2021;  Published: 19 August 2021;  doi: 10.21926/obm.icm.2103024

Photobiomodulation (PBM), as well as plant extracts of Calendula officinalis (Calen), Hypericum perforatum (Hyper), and Echinacea purpurea (Echi-p), have been used to accelerate wound healing. However, the use of homeopathic preparations of these medicinal plants, in combination with PBM, is unknown. The objective of this study was to investigate the combined wound healing potential of these therapies in vitro. Various cell models were created in vitro in commercially available human skin fibroblasts (WS1). PBM was [...]

by Shiping Wang  , Georg Bendt  and Stephan Schulz

Received: 24 May 2021;  Published: 16 July 2021;  doi: 10.21926/cr.2103001

One-pot synthesis of mesoporous hybrid material consisting of Mn-Co/CoO nanoparticles encapsulated in an N-doped graphene shell decorated with Mo2C nanoparticles (Mo2C-NC@Mn-Co/CoO) was reported. The Mn and Mo components synergistically refined the graphitized carbons due to the interactions with N and C atoms while promoting the stability of the Co/CoO nanoparticles. These components exhibited a beneficial effect on the dispersion of the active metal/metal oxide nanoparticles and the formation of a mesoporous stru [...]

by Xiuhui Tang  , Daming Zhang  and Hua Chai

Received: 19 May 2021;  Published: 08 July 2021;  doi: 10.21926/jept.2103032

In AC microgrid systems, technical issues resulting from the power control effect are the power control method efficiency and the filter resonance since voltage-frequency interference and filtering resonance may cause significant control input reduction and oscillation. A simple and robust solution is to regulate active power flow by adding an optimal passive damping resistor. The optimal LCL filter parameterization process in this paper provides an innovative approach to obtain the optimal quality factor and the o [...]

by Ibrahim Nahit Sendur  , Büsra Köksoy  and Yasemin H. Balaban

Received: 11 November 2024;  Published: 01 April 2025;  doi: 10.21926/obm.transplant.2502244

Cytomegalovirus (CMV) remains a significant cause of morbidity and mortality in solid organ transplant (SOT) recipients. Despite advancements in prophylaxis and antiviral therapy, CMV continues to pose clinical challenges in transplant medicine. This review provides a comprehensive overview of CMV, exploring its pathophysiology, epidemiology, and clinical presentation in SOT patients, in whom CMV infection can lead to direct organ involvement and systemic symptoms. Additionally, CMV has indirect effects, including [...]

by Bas T Röttgering  and Karoly Szuhai

Received: 14 May 2019;  Published: 14 October 2019;  doi: 10.21926/obm.genet.1904096

Insulin-like growth factor 2 (IGF2) is a strong mitogenic peptide with an imprinted gene that is primarily involved in fetal development. It is highly expressed in the fetus where it is involved in fetal growth and tissue differentiation. However, postnatally, the expression of IGF2 decreases despite higher expression levels in the blood as compared with that of IGF1. In adults, the physiological function of IGF2 is poorly understood; however, the possibility of a metabolic function exists. Although the expression [...]

by Ciro Comparetto  , Florence Dupré  and Franco Borruto

Received: 15 July 2019;  Published: 12 December 2019;  doi: 10.21926/obm.genet.1904101

Background: Clinical or medical genetics deals with the study and diagnosis of genetic diseases. It is oriented to the formulation of the clinical diagnosis of genetic diseases and genetic counseling to evaluate the possible reproductive risk for the patient and his/her family. The geneticists here play a role in the diagnosis and prevention of some of the diseases occurring most frequently, such as cancer and cardiovascular diseases. Methods: State-of-the-art through literature review. Results: Genetic counseling [...]

by Marianna Michałowska

Received: 11 June 2021;  Published: 18 October 2021;  doi: 10.21926/aeer.2104025

Since 1907, when Bakelite was invented, there has been a dramatic rise in the daily usage of plastic-like materials. Today, its negative impacts are a part of scientific studies and public debates. Art and artists play a significant role in these discussions. They mediate between the specialist content and public awareness. This study is dedicated to the artworks of artists using plastic waste collected from the seashore. I organized their works into three lines, within which artists have different threads of plast [...]

by Xiu-Zhi Wei  , Jianguo Liu  and Longlong Ma

Received: 28 December 2021;  Published: 21 February 2022;  doi: 10.21926/cr.2201004

In recent years, research on converting biomass platform compounds into high-value chemicals and pharmaceutical intermediates has garnered huge interest. Nitrile and amide groups are key structures in natural products and biologically active molecules. The direct conversion of biomass platform compounds into nitriles and amides will undoubtedly be an important guide for biomass utilization. In this paper, a facile and efficient triphosgene-assisted one-pot conversion for aldehydes and ketones into nitrile and amide [...]

by Andrew Hanna  and Aileen M. Pidgeon

Received: 04 April 2018;  Published: 15 May 2018;  doi: 10.21926/obm.icm.1802007

Objective: Mindfulness-based interventions (MBIs) have shown promise in cultivating resilience and are widely accepted as efficacious in the treatment of a range of psychological disorders. This paper explores the feasibility of a Mindful-Awareness and Resilience Skills Training (MARST) program to enhance mindfulness and resilience, as a means of increasing psychological well-being and alleviating burnout and compassion fatigue in human service professionals. Method: In this randomised control trial, 46 human servi [...]

by Stanislav Birko  , Marie-Eve Lemoine  , Minh Thu Nguyen  and Vardit Ravitsky

Received: 10 February 2018;  Published: 19 April 2018;  doi: 10.21926/obm.genet.1802018

Women’s reproductive autonomy, and its translation into informed free choice regarding prenatal screening, is a dominant concept in the bioethical discourse concerning prenatal screening. This discourse is based on the premise that access to information regarding the pregnancy promotes autonomous decision-making. However, studies show that the offer of prenatal screening as a routine part of pregnancy care is not supported, to a large degree, by appropriate informed consent mechanisms. This means that the implement [...]

by Amir Mahboob  , Omid Hassanshahi  , Abdulqaiyoum Hakimi  and Mohammad Safi

Received: 02 March 2023;  Published: 19 April 2023;  doi: 10.21926/rpm.2302016

The largest proportion of the material used in multistory buildings, and thus its carbon impact, is attributed to their slabs being the main contributor of weight. Because of their high strength and concrete self-weight reduction, composite beams with hollow-core slabs were created for their technical and economic benefits, making this system inexpensive and with a reduced environmental impact, thereby lowering carbon emissions. Geometrically, the hollow slab has a sequence of T and L form pieces on both sides. Hol [...]

by Bruno Riccardi

Received: 10 October 2022;  Published: 21 December 2022;  doi: 10.21926/rpn.2204023

In this article, the long journey from the production of food ingredients to their transformation into nutrients was described. The essential function of nutrients is to satisfy the primary needs of living organisms, namely energy, morphology and reproduction, through the consumption of food. Fulfilling its primary role, food must contain nutrients that are essential for the well-being of the living, along with others that are not essential but are still important for proper metabolism. These substances are known a [...]

by Sofía Albolafio  , María I. Gil  , Ana Allende  and Epameinondas Xanthakis

Received: 02 December 2020;  Published: 21 April 2021;  doi: 10.21926/rpm.2102013

The present study aimed to characterize wastewater fractions obtained after the wet extraction of proteins from legumes. In addition, the suitability of wastewater fractions for the potential recovery of high value-added compounds was also examined, and consequently, the prevention of the environmental impact of these wastes was explored. Similar to the industrial production of proteins, wet alkaline and acidic extractions of proteins from faba bean and pea flours were performed in two stages of extraction. The dif [...]

by Deborah R. Simkin  and L. Eugene Arnold

Received: 06 April 2020;  Published: 19 October 2020;  doi: 10.21926/obm.icm.2004040

Teen depression and suicide rates have risen despite conventional treatments. This article reviews adjunctive interventions that may improve outcomes. A search of the National Library of Medicine database used tailored searches with combinations of specific terms. Modern lifestyle is associated with increased inflammation and pro-inflammatory cytokines leading to, for instance, hyperactivation of the hypothalamic-pituitary-adrenal axis, which promotes depression. Inflammation also increases oxidative stress, leadin [...]

by Alexander Peller  , Lara Suarez  , Ashleigh Trapuzzano  , Matt S. Stock  and Nicole Dawson

Received: 16 November 2021;  Published: 15 February 2022;  doi: 10.21926/obm.geriatr.2201188

Gait speed has been correlated to quality of life and has been called the sixth vital sign. The purpose of this study was to understand the factors that comprise fast and comfortable gait speed. 90 older adults provided demographic, cognitive, and functional performance data. Hierarchical linear regression models revealed predictors for comfortable gait speed to be lower-extremity strength ( B = 1.13, β = 0.233, P< .05), comorbid health ( B = −2.95, β = −0.22, P < 0.05), and gender( B = [...]