An Interview with Prof. Rosita Gabbianelli
Abstract
490 2309
An Interview with Prof. Rosita GabbianelliAbstract
An Interview with Prof. Rosita Gabbianelli 490 2309 |
Duration of Hospitalization is Associated with the Gut Microbiome in Patients Undergoing Hematopoietic Stem Cell Transplantation: Early Results from a Randomized Trial of Home Versus Hospital Transplantationby
Abstract
Home-based hematopoietic stem cell transplantation (HCT) is an innovative care model with growing interest, but its impact on the gut microbiome remains unexplored in a randomized setting. We present interim results from the first randomized controlled trials (RCT) evaluating the effect of HCT location—home versus hospital—on gut microbial diversity and antimicrobial resistance (AMR) gene carriage. We hypothesize that patients randomized to undergo home HCT would have higher gut taxonomic diversity and lower AMR ge [...] 1829 4926 |
Fairness and Reasonableness Tariff Indicator (FRTI) to Meter and Compare Rate Policy in the Electricity Regimes. The Case of Argentina in 2022Abstract
The tariff policy for energy services is a fundamental issue for today's societies, especially for end users, including residential, commercial, and industrial. The main objective of this paper is to propose a statistical method to calculate, compare, and evaluate policies of this nature. To this end, firstly, it is intended to rethink an old concept on this type of policy, the principle of fairness and reasonableness, through the linkage with the perspective of human rights, specifically with the right to energy, [...] 928 5241 |
Physiological Impact of Milk on Multiple Health Outcomes in HumanAbstract
Milk is best known as a nutrient-rich fluid produced by the mammary glands of mammals, designed primarily to feed young. In the human diet, cow milk is most prevalent, but milk of other mammals and plant milk are common too. This study aims to investigate milk's nutritional value in various age groups and review opposing evidence of its effect on cardiovascular diseases in adults. It is a literature-based strategy to synthesize information from observational and meta-analytic studies. The milk content—macronutrient [...] 1978 9984 |
A Review on the Ethnomedicinal Plants Used in Zimbabwe for the Treatment and Management of Skin Conditions: Perspectives on Pharmacological and Toxicological Evaluationby
Abstract
Medicinal plants remain central to healthcare in Africa, where up to 80% of the population relies on traditional remedies to manage a range of health conditions, including skin ailments. In Zimbabwe, the country's rich biodiversity and favourable agroecological zones support a diverse range of ethnomedicinal plants. However, much of the knowledge surrounding these plants remains dispersed and scientifically under-evaluated. This review consolidates evidence from ethnobotanical surveys, peer-reviewed research, and g [...] 1709 12410 |
Plant-Derived Nanoparticles in Cancer Therapy: A Comprehensive Review of Recent Advances and Future ProspectsAbstract
Cancer continues to be one of the leading causes of global death, and conventional therapies have limited efficacy because of their toxicity, drug resistance, and off-target effects. Plant-derived nanoparticles (PDNPs) have emerged as suitable alternatives as they have biocompatibility, biodegradability, and multifunctional therapy. In this review, we discussed the recent advancements in PDNPs for cancer therapy, including the green synthesis of PDNPs using phytochemical (flavonoids, terpenoids) reducing and cappin [...] 1450 7470 |
Trends in Breast Cancer Epigenetics Research from 1993 to 2023: A Bibliometric AnalysisAbstract
Breast cancer is a significant health problem. Epigenetic alterations that influence gene expression were implicated in breast cancer pathogenesis. Bibliometric analysis can be done to evaluate the existing literature and identify gaps and emerging trends. This bibliometric analysis aims to provide an overview of the current landscape of global breast cancer epigenetics research, identify existing networks of countries and authors’ keywords, and assess the association of a country’s socioeconomic indica [...] 746 4687 |
A Systematic Literature Review on the Application of Explainable AI Approaches in the Assessment of Autism Spectrum DisorderAbstract
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder associated with significant heterogeneity in symptoms and comorbid conditions. Studies have shown the value of early and accurate diagnosis in mitigating the associated social and behavioral challenges. Recently, studies have demonstrated the potential of machine learning (ML) models in identifying ASD patterns from neuroimaging, genetic, and behavioral data. However, the limited interpretability of these models poses a barrier to their clinical adopti [...] 894 7203 |
Loneliness or Solitude: How Are They Different?by
Abstract
Loneliness, social isolation, aloneness, and solitude may be used interchangeably by some who may miss the difference between them. Loneliness is the experience of being alone, or perceiving that one is alone and unimportant to others. Solitude is being geographically isolated out of one’s choice. Loneliness is not a feeling, but a multidimensional construct which is expressed cognitively, behaviorally and affectively. solitude is also reviewed and a clear distinction between loneliness and solitude is established. [...] 1645 10542 |
Lithium Stable Flexible Polyethylene Oxide-Based Composite Electrolyte with High Lithium-Ion Conducting NASICON-Type Solid Electrolyte for Lithium BatteriesAbstract
Solid lithium-ion conducting polymer electrolytes are attractive candidates for battery applications because they are flexible and less flammable, and can be easily prepared as large-sized thin films. However, the room temperature conductivity of conventional polymer electrolytes is relatively low, and detrimental lithium dendrite formation is observed at high current density. In this study, a composite polymer electrolyte of polyethylene oxide (PEO) with lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) and a hi [...] 941 5342 |
Feasibility and Physiological Effects of a Home-Based Swallow Exercise Program Using sEMG Biofeedback in Prefrail Older Adults: A Case Seriesby
Abstract
Age-related decline in swallowing function increases the risk of dysphagia in older adults. Strengthening the muscles involved in swallowing through proactive training may help prevent such decline, particularly in prefrail individuals. This case series evaluated the feasibility and physiological effects of a home-based effortful swallow training program in three prefrail older adults without swallowing impairments. The intervention used a wearable surface electromyography biofeedback device (Mobili-T®) to provide [...] 837 5131 |
Applications of Generative Large Language Models in Environmental Science: A Systematic Reviewby
Abstract
Environmental science addresses critical global challenges, including climate change, biodiversity loss, and sustainability. These complex topics generate a vast amount of both structured and unstructured data, from remote sensing output to policy documents, guidelines, and scientific literature. Effectively processing and utilizing this information is essential for advancing research and supporting decision-making. Large Language Models (LLMs) have shown remarkable capabilities in natural language understanding an [...] 2193 10975 |
Transforming Community Strategy from Population Health to Quality Aging — The Role of Digital Technologiesby
Abstract
Aging is a multifaceted journey shaped by diverse life-course experiences, which contribute both to the challenges populations face in achieving their health goals and to the competencies they can bring to sustain health and aging. Community strategies designed to support population health—by leveraging technology and external partners—require transformation to effectively extend their focus to aging-related goals. In this paper, we adopt a service lens to examine how these community strategies, which co-produce pr [...] 883 5387 |
Maximal 4-Second Cycle Accelerations Attenuate Sarcopenia and Improve Cardiovascular Function in Older AdultsAbstract
The shrinkage of muscles with age, beginning at 30 y and accelerating in old age, is due largely to atrophy of fast-twitch muscle fibers (FT) partly from disuse. It was our purpose to develop an exercise program that is effective and time efficient at stimulating FT, as well as slow-twitch fibers (ST), to offset their atrophy. FT are recruited during movements requiring very high force and/or high velocity. We developed a safe exercise cycle that allows a person to ‘accelerate’ with the maximal effort needed to rec [...] 860 4331 |
Treatment Choices and Healthcare Services Utilization Amongst Lumbosacral Radiculopathy Patients: Results from a Randomized Controlled Trialby
Abstract
Lumbosacral radicular pain (LRP) is a common sequelae of low back pain, the world’s leading cause of years lived with disability. LRP typically causes numbness, weakness, and tingling into the lower extremity and is associated with high rates of pain and impaired function. Despite its prevalence, there is significant heterogeneity among clinical practice guidelines for the treatment of LRP, which may contribute to poor patient outcomes. The aim of the present study was to identify treatments that participants [...] 2109 5453 |
Morpho-Biochemical Characterization and Genetic Analyses of the Traits of Mungbean Genotypes Confined with Yield Attributing Traits and Salinity Stress Toleranceby
Abstract
Low phenotypic and genotypic variability for yield-attributing traits and susceptibility to salinity stress are constraints of mungbean productivity. The objectives of the study are to phenotype a set of exotic mungbean genotypes for yield-attributing traits and salinity tolerance, as well as to conduct genetic analysis of these traits for efficient selection. Three consecutive experiments were conducted to fulfill these objectives. In the first experiment, 26 mungbean genotypes were evaluated for yield traits unde [...] 1141 5560 |
Exercise Training and Cardioprotection in Cardiovascular Disease: A Review of MechanismsAbstract
Cardiovascular disease remains the leading cause of death worldwide, prompting extensive research into effective methods for treatment and prevention. Among these, exercise training and physical activity are widely recognized as the safest and most effective strategies for improving health. Specifically, exercise training has been explored for its role in cardioprotection, particularly in reducing damage caused by ischemia-reperfusion (I/R) injury and myocardial infarction (MI). Both high-intensity interval trainin [...] 743 4155 |
Advancing Objective Pain Measurement: Exploring the Potential of Electroencephalography BiomarkersAbstract
Chronic pain involves complex cortical and subcortical changes, suggesting that brain electrical activity may be a potential biomarker for nociceptive processing. Pain leaves its signature in the brain's oscillatory patterns, yet limited studies have explored the neurophysiological alterations associated with chronic pain. This review examines the pain detection method currently used in clinical settings, the potential of neurophysiological features to become brain oscillatory brain biomarkers, and their use in fut [...] 1327 7885 |
Maladjustment in Minority Youth from Community Network Disparities in the COVID-19 Lockdown Environmentby
Abstract
Pandemic lockdown orders resulted in closures to critical community networks. One such infrastructure was community recreation centers/parks. This infrastructure serves a critical role in building psychosocial wellness for youth. Socioeconomic minority youth face baseline disparity in center/park distribution and services. Youth recreation activity declined 50% as result of lockdown orders with corresponding decline in youth mental health status. Despite overall youth activity decline, White and high socioeconomic [...] 558 2962 |
Quantum Diamonds and the Future of Advanced Processors, Review on Benefits and ChallengesAbstract
Nowadays, the development of advanced processors plays a key role in the progress of humanity and the discovery of new sciences, and quantum computers play an essential role in this regard. In this regard, the development of new generation processors is necessary for the development of quantum computers. Quantum diamonds, with their astonishing properties, especially the presence of nitrogen-vacancy (NV) centers in their crystalline structure, are among the most advanced emerging technologies in the field of quantu [...] 3387 11869 |
“At My Age, Its Perhaps the End of My Walking or the End of a Lot of My Life”: A Phenomenological Study of the Lived Experiences of a Serious Fall to Independent Older AdultsAbstract
The purpose of this original research was to describe the lived experience and meaning of a serious fall to independently residing older adults. A qualitative phenomenological approach was utilized with a purposive sample of 19, independent, high-level functioning older adult residents of a Continuing Care Retirement Community to describe their most serious fall and its personal meaning. Traced through multiple data sources, interpretive analysis of the language expressed by older adults were integrated to support [...] 804 3814 |
How Can Architectural Acoustics Reflect Levels of Stress and Relaxation in Indoor Environments? An EEG-Based Experimental StudyAbstract
The acoustic design of indoor environments encompassing spatial configuration, material properties, and sound absorption significantly influences auditory perception and psychological well-being. This study examines the interaction between architectural acoustics, musical stimuli, and neural responses within a controlled therapeutic context, focusing on their effects on stress reduction and relaxation. Electroencephalography (EEG) was utilized to measure brain activity in 24 participants exposed to six musical inst [...] 1150 7635 |
Protective Effects of Teucrium polium Extract Against LPS-Induced Oxidative Stress in BV-2 Microglia: Insights from Wild-Type and Acox1⁻/⁻ Modelsby
Abstract
Microglial activation and the associated oxidative or inflammatory responses play a crucial role in the development of neurodegenerative diseases. In this study, we evaluated the antioxidant, cytotoxic, and anti-inflammatory properties of Teucrium polium (TP) ethanolic extract in murine BV-2 microglial cells, including wild-type (Wt) and peroxisomal β-oxidation-deficient Acox1-/- cell lines. The TP extract exhibited high antioxidant activity as assessed via the DPPH test, with an IC50 value of 73.89 μ [...] 612 3398 |
Performance Art as Lifestyle: Art in Action for Health PromotionAbstract
Performance art is both a visual arts practice and kinaesthetic approach to place-based health. The perspective of this commentary is to promote the attributes of performance art to showcase its capacity to extend people into new configurations of cultural engagement with beneficial effects. Performance art is an opportunity to engage both mind and body in actions that transform predictability and encourage wellness within the context of people’s life studios (their everyday lives). Wellness is defined here in rela [...] 569 3502 |
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