by Edmund Zolnik

Received: 14 January 2022;  Published: 02 August 2022;  doi: 10.21926/jept.2203026

Monetary incentives to accelerate the transition of private vehicle fleets to zero emissions promote sustainability in the transportation sector. Clean Cars for America to incentivize transactions for new battery power vehicles is a program in furtherance of sustainable transportation goals in the United States. Unfortunately, data on transactions for new alternative fuel vehicles (AFVs) are scarce so empirical research to explore the costs and/or the benefits of such programs is also scarce. Analysis of transactio [...]

by Ginevra G Adamo  , Sergio D'Angelo  , Angeli Christy Yu  , Marco Pellegrini  , Federico Bernabei  , Vincenzo Scorcia  and Giuseppe Giannaccare

Received: 17 June 2022;  Published: 02 August 2022;  doi: 10.21926/obm.transplant.2203164

Graft-versus-host disease (GVHD) is a serious complication that may occur in patients receiving allogeneic hematopoietic stem cell transplant (HSCT). GVHD occurs because of the immunological reaction between the donor’s T cells and the recipient’s antigens; GVHD may develop in different tissues, including the eye. Corneal perforation is an uncommon but vision-threatening manifestation of GVHD. We reported the case of a 65-year-old male patient who developed corneal perforation sequentially in both eyes 3 years afte [...]

by Xinying Hong  and Miao He

Received: 04 May 2022;  Published: 02 August 2022;  doi: 10.21926/obm.genet.2203161

Galactosemia is a group of hereditary disorders of galactose metabolism. Newborn screening for galactosemia type I is mandatory in all states in the US since timely intervention can prevent life-threatening sequela. The biochemical basis, clinical presentation, and potential treatment options for different types of galactosemia are described. This review has a focus on the screening methodologies, including the principle of the assay, the transition from the initial bacteria inhibition test to the modern fluorometr [...]

by Ankit Patel  , Kevin Houston  , Michael Saadeh  , Ana Vilela  , Byung-Soo Yoo  , Steve M. D’Souza  and David A. Johnson

Received: 24 April 2022;  Published: 01 August 2022;  doi: 10.21926/rpn.2203018

Colorectal cancer (CRC) is currently the third most common cancer within the United States among both males and females, with increasing rates occurring in younger individuals compared to the past. Multiple environmental and social aspects including diet may be contributing to this increase in CRC rates. The aim of this review is to examine foods containing high fructose corn syrup, processed meats, and red meats which have shown to be linked to an increase in incidence of CRC. These foods can be a cause for disrup [...]

by Gilda F. Pardey Bracho  , Karine Collomb  and Astrig Topouzkhanian

Received: 09 May 2022;  Published: 28 July 2022;  doi: 10.21926/obm.icm.2203030

The patient as the custodian of their own care is a concept that has been evolving for several years and can help the patient to a better and quicker recovery. Medical Hypnosis (MH) assist the practitioner to reduce the patient’s pain and disorders and help the patient to understand, accept, and manage their situation. Recently, this technique has been increasingly used in awake surgery protocols. This paper describes three examples of the successful perioperative management of patients who benefited from an awake [...]

by Zsuzsanna M. Schmidt  and Gyula Poor

Received: 07 May 2022;  Published: 27 July 2022;  doi: 10.21926/obm.geriatr.2203202

Polymyalgia rheumatica (PMR) is an age-related chronic inflammatory disease with rheumatic features at the fore. In addition to the high-grade systemic inflammation, it is characterized by typical "polymyalgic" musculoskeletal symptoms, including diffuse and severe pain and prolonged morning stiffness of the shoulder girdle, pelvic girdle, and neck. PMR is a member of the so-called giant cell arteritis complex; however, in spite of the marked systemic inflammation in PMR, the local vasculitis process aborts. The pa [...]

by Ibrahim El-Serafi  , Sandra Oerther  , Ying Zhao  and Moustapha Hassan

Received: 08 July 2022;  Published: 27 July 2022;  doi: 10.21926/obm.transplant.2203163

Cytochrome P450 2J2 (CYP2J2) is one of the recently discovered enzymes that is involved in the metabolism of several drugs. It is mainly an extrahepatic enzyme which can, to some extent, explain some the drugs’ side effects such as cyclophosphamide (Cy). Cyclophosphamide is an alkylating agent that is commonly used in conditioning prior to stem cell transplantation. It is a prodrug that is bio-activated by several CYPs including CYP2J2. Cy is known to have several side effects and its extrahepatic activation by CYP [...]

by Rachel Hull  , Scott Browning  and Melanie Puzio

Received: 11 April 2022;  Published: 25 July 2022;  doi: 10.21926/obm.icm.2203029

The authors attempted to operationalize the clinical work of strategic theorist and expert family therapist, Scott Browning. Strategic therapy takes the position that a client is stuck, not necessarily sick. This focus encourages the clinician to create alternative perspectives such that a client learns to consider a problem from a new lens. Milton Erickson, a progenitor of strategic thinking, used hypnosis and paradox to nudge clients toward a useful alternative perspective [1]. The present article examined three [...]

by Olushola S. Ayanda  , Cecilia C. Oforkansi  , Omolola H. Aremu  , Oluwakemi E. Ogunjemiluyi  , Ololade L. Olowoyeye  and Cecilia O. Akintayo

Received: 26 June 2022;  Published: 25 July 2022;  doi: 10.21926/cr.2203022

In this study, we investigated the degradation of amido black dye in an aqueous solution using ultra-violet (UV) light catalyzed by iron oxide nanoparticles (nano-Fe). The nano-Fe was synthesized by sodium borohydride reduction of ferric chloride solution and was characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), and X-ray fluorescence spectrophotometry (XRF). The SEM of the nano-Fe showed regular spherical particles, the XRD examination showed a weak and broad peak at Fe (1 1 0), and the [...]

by Prabhumallikarjun Patil  and Amanda RB Weber

Received: 18 January 2022;  Published: 22 July 2022;  doi: 10.21926/obm.neurobiol.2203129

Cerebral palsy is defined as “A group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cognition, communication, and behavior, by epilepsy, and by secondary musculoskeletal problems [1].” Between 30-40% of people with cerebral palsy also have epilepsy [2,3,4]. Som [...]

by Harald P. Hoensch  and Benno Weigmann

Received: 23 March 2022;  Published: 21 July 2022;  doi: 10.21926/rpn.2203017

Flavonoids are phytochemicals (polyphenols) of plant origin. They can trap free oxygen radicals generated by mitochondria and other electronic transport chains, thereby inhibiting inflammatory and carcinogenic changes in vivo and in vitro. Why the body requires these compounds for the well-being of the organism and the maintenance of human health remains unclear. However, a deficit of flavonoids could lead to molecular malfunctions in cells, organelles, and macromolecules. This manuscript describes the occurrence a [...]

by Julia Caldwell  , Pamela Meredith  , Koa Whittingham  and Jenny Ziviani

Received: 07 March 2022;  Published: 20 July 2022;  doi: 10.21926/obm.icm.2203028

Positive perceptions of pregnancy are associated with better postpartum outcomes, including stronger relationship with baby. Although better self-reported emotional availability (EA-SR) is associated with greater attachment security with infants, research has not yet explored the relationship between prenatal maternal factors and EA-SR. The aim of the study was to explore the associations between prenatal variables (adult attachment, shame, compassion) and EA-SR at 3- and 6-months postpartum. A cross-sectional surv [...]

by Anilkumar Mettu  , Ninad Loke  , Vilas Patil  , Rahul Panday  and Sreenivasarao Gajula

Received: 10 January 2022;  Published: 19 July 2022;  doi: 10.21926/cr.2203021

In this study, we present selective hydrocracking of poly (di and tri) aromatic compounds to monoaromatics, such as benzene, toluene, and xylenes (BTX), over a mixture of Pt/Al2O3 and Y zeolites. The polyaromatic compounds feed is a combined simulated model feed, which is similar to light cycle oil (LCO) in composition. The feed is processed in a fixed bed reactor over a catalyst mixture: in the first step, selective hydrogenation of di and tri-aromatic compounds occurs in the presence of Pt/Al2O3 catalyst, followe [...]

by Fabien Leurent

Received: 10 March 2022;  Published: 18 July 2022;  doi: 10.21926/jept.2203025

The carbon footprint of motorized transport modes per unit length traveled encompasses the unit share of the vehicle lifetime emissions, that of the transport infrastructure, and those of the motor energy, considered both from “well to tank” and from “tank to wheel”. In the active modes of transport, i.e., walking and cycling, the counterpart of motor energy is human energy, which is associated with two kinds of carbon flows: the carbon footprint of food intake, – which we call the Food to Body component – and the [...]

by Jeggathishwaran Panisilvam  , Peng Cheng Wang  and Hui An

Received: 26 March 2022;  Published: 13 July 2022;  doi: 10.21926/jept.2203024

Reducing and conserving fuel usage is pivotal for any engineering system for the development of a sustainable energy solution. Proton exchange membrane fuel cells (PEMFCs) are one of the promising renewable energy systems that consume hydrogen as their source of fuel to generate electricity. This paper investigate the necessity of the constant supply of fuel (hydrogen) in the PEMFC system to ensure stable operation. We propose that a dynamic supply of fuel could help achieve similar performance and reduce the amoun [...]

by OBM Genetics Editorial Office

Received: 07 July 2022;  Published: 13 July 2022;  doi: 10.21926/obm.genet.2203160

by Zoi Portokalidou  , Anna Huysse-Gaytandjieva  and Madelon L. Peters

Received: 09 January 2022;  Published: 12 July 2022;  doi: 10.21926/obm.icm.2203027

Hashimoto thyroiditis (HT) is an autoimmune disease affecting mainly middle-aged women. Hormonal replacement is the most common therapy; however, it tackles only the functionality of the thyroid and not the autoimmunity components. Thus, patients experience persistent somatic and psychological symptoms, thereby affecting their quality of life. The cause of HT remains uncertain. Primary evidence suggests that adverse experiences in childhood are associated with autoimmune disease manifestation in adulthood; therefor [...]

by Jean-Lionel BAGOT

Received: 22 April 2022;  Published: 11 July 2022;  doi: 10.21926/obm.icm.2203026

The application of targeted therapies (TT) in oncology has prolonged survivals and even enabled complete remission of cancers previously considered incurable. With small therapeutic indices, the reduction in dosage or spacing out of the doses of TT due to side effects, represents a significant loss of treatment opportunity for the patients. In the absence of drug interaction and significant side effects, homeopathy used in supportive care improves the quality of life of patients, compliance with oncological treatme [...]

by Karine Dornela Rosa  , Tara Rava Zolnikov  , Rodrigo Souza Leite  , Sérgio Caldas  , Job Alves de Souza Filho  , Raquel Sampaio Jacob  and Marcos Paulo Gomes Mol

Received: 05 May 2022;  Published: 11 July 2022;  doi: 10.21926/aeer.2203028

Visceral leishmaniasis (VL) is a vector-borne disease that is caused by the protozoan Leishmania infantum and transmitted to humans and other mammals through the bites of infected female sandflies. VL has been prevalent in Minas Gerais, Brazil, since the 1940s. As the vector completes its reproductive cycle in the soil with organic matter, the association between the occurrence of VL and unimproved solid waste disposal sites has been investigated. Thus, in this study, we analyzed the relationship of waste disposal [...]

by Maïté Van Hentenryck  , Zhanzhuo Li  , Philip M. Murphy  and Agnieszka Czechowicz

Received: 24 November 2021;  Published: 08 July 2022;  doi: 10.21926/obm.transplant.2203162

The ability to successfully transplant cells and organs from a donor into an immunologically disparate recipient is one of the greatest treatment advances in the history of medicine. Nevertheless, acute and chronic rejection, graft versus host disease, and the inability to identify suitable donors continue to be challenges and limit broader application of cell and organ transplantation to the many patients that could benefit. Immunosuppression before and after allogeneic transplant has been found to dramatically im [...]

by Rachel Moor  , Michael Goutnik  , Brandon Lucke-Wold  , Dimitri Laurent  , Si Chen  , William Friedman  , Maryam Rahman  , Nichole Allen  , Marie Rivera-Zengotita  and Matthew Koch

Received: 30 May 2022;  Published: 07 July 2022;  doi: 10.21926/obm.neurobiol.2203128

Paragangliomas are rare tumors that may present with cranial neuropathies when located along the skull base. Supratentorial paragangliomas are less likely to secrete catecholamines but should be worked up, nonetheless. We highlight a case of a female in her fourth decade found to have a petroclival lesion following initial presentation that included one month of tooth pain, dysphagia, diplopia, hoarseness and right hemifacial hypoesthesia. Magnetic resonance imaging of the brain demonstrated a T2 hyperintense lesio [...]

by Dean M. Cordingley  and Stephen M. Cornish

Received: 29 April 2022;  Published: 07 July 2022;  doi: 10.21926/obm.icm.2203025

Sarcopenia is the age-related loss of muscle mass and strength which is associated with the loss of physical performance, lower quality of life, and other negative health outcomes. Resistance training (RT) is a recognized method to increase muscle strength and mass, however some older adults may be limited in their ability to perform RT with traditionally recommended higher-loads. Occluding blood flow to a limb, commonly referred to as muscle blood flow restriction (MBFR), has been investigated as an adjunct to RT [...]

by Luiz Felipe da M. Rocha  , Leonardo C. Ferreira  , Maria de Fatima V. Marques  , Rodrigo S. Bitzer  and Marco Antônio Chaer Nascimento

Received: 18 May 2022;  Published: 06 July 2022;  doi: 10.21926/cr.2203020

We synthesized and spectroscopically characterized a new heterotrimetallic {Ti2Ni} ethylene (co)polymerization precatalyst containing one (α-diimine)NiBr2 and two (phenoxy-imine)TiCl4 scaffolds. Its calculated structure was investigated at the DFT B3LYP/LACVP** level. Our calculations showed that the titanium(IV) centers were in a slightly distorted trigonal bipyramidal environment, and the average Ti···Ni distance was 8.76 Å. The precatalyst was used for synthesizing polyethylene a [...]

by Sofie Amalie Andersson  , Mathias Møller Thygesen  , Anita Dittrich  and Henrik Lauridsen

Received: 07 March 2022;  Published: 06 July 2022;  doi: 10.21926/obm.neurobiol.2203127

The Mexican axolotl salamander is an important model species in regenerative medical research and experiments involving this species often require anesthesia which is usually limited to the duration of the surgical procedure or other interventions, usually lasting no more than a few hours. This study aimed to examine the potential for increasing the duration of anesthesia by continued propofol infusion for a week. Neurobehavioral changes in response to prolonged anesthesia were evaluated after two and seven days of [...]

by Vjollca Ndreu  , Yllka Themeli  , Ilirjana Zekja  and Fatjona Kamberi

Received: 02 April 2022;  Published: 06 July 2022;  doi: 10.21926/obm.neurobiol.2203126

The World Health Organization declared the COVID-19 pandemic on March 11th, 2020. The pandemic had significantly affected public health, and the mental health of people was compromised regardless of age or socioeconomic status. In this study, we measured the psychological distress caused by the pandemic and determined the associated factors. An online survey was conducted from November 16th (2020) to January 31st (2021). The participants were Albanian adults (≥18 years old). The call to participate was poste [...]