Table of Content

Open Access Original Research

Moldavian Dragonhead Extract: A Natural Collagen-Booster to Target Skin Aging

Received: 09 December 2024;  Published: 03 April 2025;  doi: 10.21926/obm.geriatr.2502305

Abstract

The complex process of skin aging results in noticeable changes, including decreased collagen content, reduced elasticity, and decreased hydration. Interventions to preserve or restore collagen, a key structural protein, may help counteract these signs. The concept of "beauty from within” through nutritional supplements is of growing interest, particularly the use of plant-based alternatives to animal-derived or synthetic collagen. This study investigated the anti-aging potential of an extract from Moldavian dragon [...]

1086 10253

Open Access Case Report

Oral Features in Children with X-Linked Hypophosphatemic Rickets: An 8-Year Follow-Up Case Report

Received: 19 March 2024;  Published: 03 April 2025;  doi: 10.21926/obm.genet.2502290

Abstract

X-linked hypophosphatemic rickets (XLHR) is a hereditary metabolic disease caused by the loss of phosphate through the renal tubules into the urine and an associated decrease in serum calcium and potassium phosphate, resulting in bone and dental abnormalities. We report this case, aiming to describe, through an 8-year follow-up case report, the clinical approach adopted in managing dental features in both primary and permanent dentition in a child diagnosed with XLHR. The oral manifestations were mainly premature e [...]

756 3872

Open Access Concept Paper

Enhancing Biodiversity Education and Outreach for Conservation Awareness and Environmental Stewardship

Received: 15 August 2024;  Published: 02 April 2025;  doi: 10.21926/aeer.2502016

Abstract

Biodiversity—the rich variety of life on Earth—is essential for ecosystem stability and resilience, which, in turn, supports human well-being. However, human activities, such as habitat destruction, pollution, overexploitation, and climate change, are placing unprecedented pressures on global biodiversity, emphasizing the need for urgent conservation measures. In response, biodiversity education and outreach initiatives have become pivotal in fostering conservation awareness and action. This paper critically evalua [...]

1892 11517

Open Access Original Research

A Novel Approach to Carbon Monoxide Removal Using Transition Metal-Doped Boron Nitride Nanosensors for Environmental Sustainability

Received: 12 November 2024;  Published: 02 April 2025;  doi: 10.21926/jept.2502006

Abstract

Adsorption of toxic gas of CO molecules by using transition metals of X (X = Ti, V, Cr, Co, Cu, Zn)-doped boron nitride nanocage (B5N10_NC) has been studied by computational chemistry. Based on NQR analysis, X-doped on B5N10_NC has shown the lowest fluctuation in electric potential and the highest negative atomic charge, including 0.2331 (copper), 0.3112 (cobalt), 0.5883 (chromium), 0.6853 (zinc), 0.6893 (vanadium) and 0.7499 coulomb (titanium), respectively, have presented the most tendency for being the electron [...]

947 4497

Open Access Original Research

Entropy and War, Toy Models

Received: 05 February 2025;  Published: 02 April 2025;  doi: 10.21926/rpse.2502007

Abstract

This study investigates the relationship between entropy and societal dynamics, with a particular focus on the origins and implications of war. By using entropy as a measure of uncertainty and inequality, the research examines societal stability through patterns of stratification and wealth distribution. Employing simplified models of various wealth distributions, the study explores their effects on social stratification and the potential for conflict. Drawing on historical and contemporary examples, it delves into [...]

892 8984

Open Access Review

Poly ε-Caprolactone Scaffolds: Advancements in Bone Regeneration and Grafting

Received: 20 October 2024;  Published: 02 April 2025;  doi: 10.21926/obm.transplant.2502245

Abstract

In orthopedics and oncology, benign and malignant bone lesions pose significant clinical challenges. Malignant tumors, like osteosarcomas and multiple myeloma, pose substantial health dangers and can spread common and mostly non-life-threatening benign lesions, including non-sizing fibromas and unicameral bone cysts. Treatment plans for bone lesions may involve radiation, chemotherapy, and surgical excision, depending on their type. Combining stem cell research, bioactive materials, and advanced scaffold design, cu [...]

1045 8579

Open Access Review

Pregnancy Risk Factors in Cerebrovascular Disease

Received: 16 May 2024;  Published: 01 April 2025;  doi: 10.21926/obm.neurobiol.2502282

Abstract

Cerebrovascular diseases such as strokes and cerebral hemorrhages are important causes of death in the world, which increase during pregnancy due to physiological conditions. This study investigated risk factors such as diabetes mellitus, hypertension and other factors by searching in databases. After searching, 35 articles were reviewed based on the inclusion criteria. The inclusion criteria included articles from 2014-2024 related to the words "pregnancy" AND "cerebrovascular disease." The obtained results were e [...]

595 4045

Open Access Research Article

An Analysis of Thermal Comfort in a School’s Outdoor Space: A Case Study of a Typical School, Dubai, UAE

Received: 29 October 2024;  Published: 01 April 2025;  doi: 10.21926/aeer.2502015

Abstract

Outdoor school spaces are significant, as they provide great opportunities for outdoor exploration, leading to the overall enhancement of a student’s well-being. This paper analyzes the outdoor school spaces in Dubai to optimize them and ensure their thermal comfort. To achieve this aim, using a mixed methodology approach of survey, field observation, workshops and ENVI-met V5.3 software simulation, the existing outdoor spaces were analyzed and then enhanced using several proposed heat mitigation strategies. The im [...]

1161 10857

Open Access Review

Diagnosis of Infectious Diseases by CRISPR/Cas System

Received: 18 November 2024;  Published: 01 April 2025;  doi: 10.21926/obm.genet.2502289

Abstract

Since the initial discovery of the CRISPR system in bacteria as an adaptive immune system, a deeper understanding of CRISPR structure and function has made it possible to perform gene editing, gene therapy, and revolutionize the diagnostic field. One of the exciting applications of the CRISPR-Cas system is used as a tool for the rapid diagnosis of infectious diseases and their treatment and the prevention of infection spread among people. The CRISPR-based diagnostic system could be the next-generation standard beca [...]

1462 18938

Open Access Review

Simulation Software in the Design and AI-Driven Automation of All-Terrain Farm Vehicles and Implements for Precision Agriculture

Received: 26 August 2024;  Published: 01 April 2025;  doi: 10.21926/rpse.2502006

Abstract

Precision agriculture depends on the automation and mechanization of agricultural equipment and vehicles in a variety of terrains, which increases productivity and sustainability. This review presents a comparative analysis of significant simulation software used in designing and developing automated agricultural systems, emphasizing their methodologies and significance in advancing farm technology. Artificial intelligence (AI) and machine learning (ML) methods are modeled, optimized, and integrated using key techn [...]

2981 19950

Open Access Original Research

Identification of Soybean Components that Prevent the Entry of Influenza Virus

Received: 31 August 2024;  Published: 01 April 2025;  doi: 10.21926/rpn.2502005

Abstract

We have previously demonstrated the anti-influenza virus activity of a soybean extract, indicating the presence of compounds that prevent viral entry into cells. In this study, we sought to identify the compounds in hydrothermal extracts of soybean that blocked viral entrance and analyzed their mechanisms of action. Hot aqueous extracts of roasted soybeans were separated by reverse-phase chromatography on an octadecylsilyl C18 column, and the antiviral activity of individual fractions was measured during the viral [...]

955 4750

Open Access Review

Cytomegalovirus Management in Solid Organ Transplant Recipients

Received: 11 November 2024;  Published: 01 April 2025;  doi: 10.21926/obm.transplant.2502244

Abstract

Cytomegalovirus (CMV) remains a significant cause of morbidity and mortality in solid organ transplant (SOT) recipients. Despite advancements in prophylaxis and antiviral therapy, CMV continues to pose clinical challenges in transplant medicine. This review provides a comprehensive overview of CMV, exploring its pathophysiology, epidemiology, and clinical presentation in SOT patients, in whom CMV infection can lead to direct organ involvement and systemic symptoms. Additionally, CMV has indirect effects, including [...]

1358 14990

Open Access Case Report

Forgiveness Therapy to Reduce Violent Behavior in Individuals with Schizophrenia: A Case Study

Received: 03 December 2024;  Published: 26 March 2025;  doi: 10.21926/obm.neurobiol.2501281

Abstract

This study aims to describe the application of forgiveness therapy as a psychosocial intervention for a schizophrenia patient with violent behavior. Mr. M, a 19-year-old male diagnosed with schizophrenia, exhibited psychotic symptoms, including auditory hallucinations, persecutory delusions, agitation, and aggression. He had a history of trauma due to physical violence from his brother. The patient was diagnosed with a risk for violence toward others. Forgiveness therapy was implemented over six sessions, each last [...]

1272 6718

Open Access Original Research

Investigating Interest in Cancer Predisposition Testing and Expanded Carrier Screening in Routine Gynecologic Care among Pregnancy Capable Individuals

Received: 28 May 2024;  Published: 25 March 2025;  doi: 10.21926/obm.genet.2501288

Abstract

The goal of this qualitative study was to explore pregnancy capable individuals’ perceptions of having cancer predisposition testing (CPT) and/or expanded carrier screening (ECS) during routine gynecologic care and how these perceptions differ across individuals. A thematic analysis was conducted based on qualitative data from 26 semi-structured interviews with women between 20 and 35 years of age at a single academic health center in the Mountain West of United States. The analysis indicated that participants’ int [...]

1083 4508

Open Access Original Research

Machine Learning Analysis of the Impact of Increasing the Minimum Wage on Income Inequality in Spain from 2001 to 2021

Received: 31 July 2024;  Published: 25 March 2025;  doi: 10.21926/rpse.2501005

Abstract

The main aim of this work is to analyze the impact of the National Minimum Wage (NMW) on wealth redistribution in Spain during the 2001-2021 period. This research addresses a fundamental question: Does increasing the minimum wage effectively reduce income inequality and contribute to a more equitable wealth distribution without negatively impacting overall economic growth and employment? Using a complete statistical census provided by the Spanish Tax Administration Agency, this study examines how the increase in th [...]

1420 7264

Open Access Original Research

Influence of Teachers’ Secondary Traumatic Symptoms on Their Burnout, Compassion Fatigue, and Intentions to Resign in Low Socioeconomic Status Schools

Received: 09 September 2024;  Published: 24 March 2025;  doi: 10.21926/obm.icm.2501016

Abstract

The current study explored the adverse outcomes of secondary traumatic symptoms experienced by secondary school teachers on their compassion fatigue, burnout, sense of satisfaction, and intention to resign from the teaching profession in low SES schools in the United States context. The study was inspired by Ludick and Figley’s Compassion Fatigue and Resilience model and Figley’s work on Compassion Fatigue. A non-experimental design was employed, and data were gathered from a random sample of 131 teache [...]

1397 8631

Open Access Research Article

Do We Care about Preschool Children's Leisure Time? Correlations between Anxiety Symptoms and Leisure Time Allocation. Results of a Cross-Sectional Study

Received: 06 January 2025;  Published: 24 March 2025;  doi: 10.21926/obm.neurobiol.2501280

Abstract

Children's leisure time in the Western world is changing compared to what it used to be in the previous decades. Children's involvement in organized activities and screen time use is increasing, while outdoor play, despite once being the main leisure time activity for children, is declining. Gray, Oliver and other contemporary theorists link this shift in children's lifestyles to an increase in the prevalence of anxiety disorders. This study aimed to determine whether allocating preschool children's [...]

1231 7450

Open Access Case Report

Pregnancy-Associated Spontaneous Coronary Artery Dissection: Anesthetic Considerations

Received: 29 August 2024;  Published: 20 March 2025;  doi: 10.21926/obm.transplant.2501243

Abstract

Spontaneous coronary artery dissection (SCAD) accounts for one-third of all peripartum myocardial infarction. Peripartum SCAD is associated with increased severity. We surmise that altered maternal cardiac physiology increases susceptibility to SCAD and warrants consideration when managing cardiac ischemia. One week after vaginal delivery, a 35-year-old woman with no known medical history developed multivessel SCAD and cardiogenic shock after attempted percutaneous coronary intervention, requiring rescue CABG and p [...]

947 4966

Open Access Interview

An Interview with Prof. Takashiro Akitsu

Received: 19 March 2025;  Published: 19 March 2025;  doi: 10.21926/rpse.2501004

715 3722

Open Access Concept Paper

Improving Outcomes in Elderly Patients with Ovarian and Pancreatic Cancer through Multimodal Prehabilitation

Received: 19 August 2024;  Published: 19 March 2025;  doi: 10.21926/obm.geriatr.2501304

Abstract

Elderly patients with ovarian and pancreatic cancer frequently experience malnutrition and sarcopenia, which negatively impact treatment tolerance, functional outcomes, and survival. The increasing use of neoadjuvant chemotherapy in this population necessitates structured interventions to mitigate these challenges. While prehabilitation has shown promise in enhancing treatment tolerance and quality of life, its role during chemotherapy remains underexplored. This prospective study evaluates the feasibility and impa [...]

968 5569

Open Access Original Research

Increasing the Omega-3 Index of Endurance Trained Adults: A Pilot Study Comparing Microencapsulated Algae to Fish Powders Provided as Chewable Tablets

Received: 12 November 2024;  Published: 19 March 2025;  doi: 10.21926/rpn.2501004

Abstract

Long-chain omega-3 fatty acids (LCn-3PUFA), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), support heart function during exercise and recovery by incorporating into the cardiac cell membranes. Traditionally sourced from fish and fish oil, algae-derived LCn-3PUFA have become alternative in supplemental forms. This study evaluated whether 12 weeks supplementation of a microencapsulated algal oil, delivered as chewable tablets, would perform equivalently to fish-derived LCn-3PUFA in boosting the [...]

1702 24217

Open Access Review

Functional Prognosis of Spinal Cord Injury Due to Spinal Tuberculosis

Received: 03 October 2024;  Published: 18 March 2025;  doi: 10.21926/obm.neurobiol.2501279

Abstract

Spinal tuberculosis (TB), an extrapulmonary manifestation of TB, primarily involves one or multiple vertebrae, with a high prevalence at the thoracolumbar region, which can compromise spinal cord integrity and result in severe sequelae such as paraplegia, bladder and bowel dysfunction, and mobility limitation. This study aimed to review medical, surgical, and rehabilitation management, clinical outcomes, and prognostic factors of spinal TB with spinal cord injury (SCI). Research was conducted utilizing databases su [...]

1318 8857

Open Access Original Research

A Pilot Study of a School-Based Yoga and Mindfulness Program for Girls

Received: 15 August 2024;  Published: 18 March 2025;  doi: 10.21926/obm.icm.2501015

Abstract

Schools have made commendable efforts to incorporate yoga and mindfulness programs to address the wellbeing of students; however, research on the efficacy of school-based yoga and mindfulness programs is still in its infancy, particularly with school-aged students at risk of developing externalizing disorders. Much of the research has also focused on evaluating interventions implemented by researchers, rather than evaluating those implemented by the school and its staff. The aim of this pilot study was to evaluate [...]

1763 10734

Open Access Review

The Independence Principle - A Neglected Feature of the Hodgkin Huxley Legacy

Received: 19 May 2024;  Published: 17 March 2025;  doi: 10.21926/obm.neurobiol.2501278

Abstract

The legacy of Hodgkin and Huxley rests on their squid giant axon studies, which were summarised in an empirical model of impressive predictive power that successfully quantified the permeability changes of excitable membranes and accurately reconstructed the action potential. Hodgkin and Huxley applied the independence principle to their experimental data in order to reveal potential mechanism(s) of trans-membrane ion movements. This was motivated by their lack of information on the manner in which ions crossed the [...]

826 4459

Open Access Review

Neurotoxicity Following Exposure to Micro and Nanoplastics

Received: 13 December 2024;  Published: 16 March 2025;  doi: 10.21926/obm.neurobiol.2501277

Abstract

The pervasive presence and enduring existence of micro and nanoplastics in the environment render their exposure to humans and aquatic creatures unavoidable. Research indicates these tiny plastic particles can be taken in by aquatic beings and mammals. Once within the body, micro and nanoplastics have the capability to infiltrate the brain, although the level of penetration and the subsequent neurotoxic effects are not fully explored. Previous studies indicate that metal (oxide) nanoparticles can enter the brain an [...]

3502 19950

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