by Tayseer A. S. Idrees  and Ibtisam E. M. El Zubeir

Received: 06 April 2024;  Published: 27 April 2025;  doi: 10.21926/rpn.2502009

This study was conducted to investigate the effect of sources. locations and seasons (late summer and winter) on the chemical composition of cow milk collected from Khartoum State. The samples were collected randomly in the morning or the evening. Two hundred and seventy milk samples were collected from farms (90 samples), groceries (90 samples) and vendors (90 samples) in Khartoum State during the late summer and winter seasons, 135 samples each. The milk samples were kept in cool cracked ice and transported immed [...]

by Camilo A. Velasquez  , Simon Yaguare  , Sabrina Gambini  , Elizabeth McElhiney  and Suresh Keshavamurthy

Received: 19 September 2024;  Published: 27 April 2025;  doi: 10.21926/obm.transplant.2502248

Lung transplantation (LTx) is the gold standard for the surgical treatment of end-stage lung disease. Ongoing discussions persist whether single lung transplantation (SLT) or bilateral lung transplantation (BLT) lead to better patient outcomes and quality of life. This study analyzed 58 peer-reviewed articles from 1990 to 2024, comparing SLT and BLT across several parameters, including indications for transplantation, overall survival, pulmonary hypertension, complications, chronic rejection, functional status, and [...]

by Abubakar Siddiq Salihu  , Wan Mohd Nuzul Hakimi Wan Salleh  , Nurunajah Ab Ghani  , Mohd Hafiz Arzmi  , Bunleu Sungthong  and Ravikumar Kapavarapu

Received: 05 March 2025;  Published: 27 April 2025;  doi: 10.21926/obm.neurobiol.2502286

The Myristicaceae family, particularly the Knema genus, is renowned for its diverse bioactive compounds, including lignans, flavonoids, and phenolics. This study explores the phytochemical profile of Knema hookeriana Warb. leaves and evaluates their potential as acetylcholinesterase (AChE) inhibitors. Phytochemical extraction was performed using a cold maceration method with a polarity-gradient solvent system (hexane, ethyl acetate, and methanol). The isolated compounds were purified through chromatographic techniq [...]

by Monday Uchenna Obaji  , Angus Nnamdi Oli  and Malachy C Ugwu

Received: 12 December 2024;  Published: 23 April 2025;  doi: 10.21926/obm.genet.2502293

Cytokines are pivotal regulators of immune responses. They are critical in mediating inflammation, recruiting immune cells, and driving pathogen clearance. Among these, interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor-alpha (TNF-α) stand out as key players in pediatric immunity, as they exhibit unique expression patterns that reflect the dynamic nature of the developing immune system. This review explores the dual roles of these cytokines in orchestrating immune defense and their potential as d [...]

by Recent Progress in Nutrition Editorial Office

Received: 17 April 2025;  Published: 22 April 2025;  doi: 10.21926/rpn.2502008

by Amjad Mizyed

Received: 23 December 2024;  Published: 21 April 2025;  doi: 10.21926/jept.2502007

Water scarcity is one of the most pressing global challenges, particularly in arid and semi-arid regions. In this context, the Gaza Strip, where groundwater is the only available natural water resource, faces severe water stress due to overexploitation and drought conditions. This study aimed to review the recent water budget for the Gaza Strip by collecting data for the years (2021-2022) which was analyzed, discussed, and compared with other studies. The results showed a sharp deterioration in the Gaza Strip in te [...]

by Mojtaba Ehsanifar  , Akram Gholami  and Alireza Esmaeili

Received: 27 October 2024;  Published: 18 April 2025;  doi: 10.21926/obm.neurobiol.2502285

There is growing scientific concern regarding how endocrine-disrupting chemicals (EDCs) impact central nervous system (CNS) disorders. Both anecdotal and preclinical studies suggest a link between EDC exposure and major depressive disorder (MDD), potentially leading to neurodegenerative outcomes. EDCs primarily exhibit their biological effects by interacting with hormone receptors. Nonetheless, there is scientific evidence pointing to dysfunction in the hypothalamic-pituitary-gonadal-adrenal axis, which is linked t [...]

by Fabian Banda  , Leonard Simukoko  , Mulenga Kalumba  and Mwansa Kaoma

Received: 26 September 2024;  Published: 17 April 2025;  doi: 10.21926/aeer.2502020

Aquatic weeds present significant ecological and socio-economic challenges in the Bangweulu Wetlands of northern Zambia, where their proliferation disrupts aquatic ecosystems, impedes fishing activities, and affects local livelihoods. Despite these challenges, aquatic weeds also offer a unique opportunity for sustainable biochar production, a clean alternative cooking fuel that can alleviate pressure on diminishing forest resources. This study explores the application of machine learning (ML) techniques to estimate [...]

by M. Lourdes Mourelle  and Leonel Pereira

Received: 26 January 2025;  Published: 17 April 2025;  doi: 10.21926/obm.geriatr.2502308

The increasing consumer demand for cosmetic products has led to the widespread use of synthetic substances, which are inexpensive and readily available but can sometimes harm the skin and body. Examples include hydroxybenzoic acid esters (parabens) and phthalates, which are considered endocrine disruptors, and synthetic fragrances that may cause irritation or allergies. Consequently, there has been a shift in consumer preferences towards natural cosmetic products. In response to this demand and the expanding market [...]

by Michael J Eiswerth  and Joel Wedd

Received: 30 November 2024;  Published: 17 April 2025;  doi: 10.21926/obm.transplant.2502247

The prevalence of alcohol use disorder (AUD) and alcohol-related liver disease (ALD) has increased in the last two decades. ALD is currently the most common indication for both waitlist additions and liver transplant (LT) in the United States, including alcohol-associated cirrhosis, alcohol-associated hepatitis (AH), and acute-on-chronic liver failure (ACLF). ALD also has a significant global disease burden. LT in ALD is a complex paradigm that poses both medical and ethical challenges, requiring a multidisciplinar [...]

by Matthieu Tshanga  , Faidance Mashauri  and Pierre Mashala

Received: 19 September 2024;  Published: 16 April 2025;  doi: 10.21926/aeer.2502019

This study examines the hydrochemical characteristics of groundwater in the Mutoshi mining environment in Kolwezi, Democratic Republic of Congo, addressing gaps in understanding the impact of mining on water quality. Despite the DRC's vast water resources, only 26% of the urban population has access to safe drinking water, with the Mutoshi aquifer, providing over a quarter of Kolwezi's drinking water, facing deterioration due to underlying copper and cobalt-rich geological formations. Groundwater and geological sam [...]

by Kajsa Landgren  , Hólmfríður Margrét Bjarnadóttir  , Helga Sif Friðjónsdóttir  and Jóhanna Bernharðsdóttir

Received: 19 December 2024;  Published: 15 April 2025;  doi: 10.21926/obm.icm.2502018

Depression, insomnia, cravings, and anxiety are significant and often long-lasting health problems. As medication has limited effect and often side effects, complementary methods such as ear acupuncture are used in mental health care. To describe mental health care users' experiences of ear acupuncture, including ratings of sleep, anxiety, depression, stress, pain, and cravings. This mixed methods study included in- and outpatients at a mental health rehabilitation service in Iceland. Standardized ear acupuncture ( [...]

by Mojtaba Ehsanifar  and Alireza Esmaeili

Received: 14 January 2025;  Published: 15 April 2025;  doi: 10.21926/obm.neurobiol.2502284

Neurotoxicity occurs when exposure to a biological, chemical, or physical agent, especially a neurotoxin, alters the normal activity of the nervous system in a way that results in permanent or reversible damage to neurons and nerve tissue and disrupts the functioning of the brain and nervous system. Chlorpyrifos is a broad-spectrum organophosphorus insecticide that has been used worldwide for more than 50 years and can damage the nervous system of insects by creating neurotoxicity. Epidemiological studies show that [...]

by Ayub Nor Hanin  , Mat Yunus Abdul Masani  , Ong-Abdullah Janna  , Omar Abdul Rasid  and Ghulam Kadir Ahmad Parveez

Received: 18 December 2024;  Published: 15 April 2025;  doi: 10.21926/obm.genet.2502292

Oil palm is the most productive vegetable oil crop compared to other oil-bearing crops because it produces the highest oil yield per hectare. Palm oil is very versatile since it is used for producing food and beverages, personal care and cosmetics, cleaning products, biofuel, and bioenergy. To cater to the increasing demand in the global palm oil market, much research has been done to improve the oil's yield and modify its quality in addition to the oil palm height through breeding. Due to its long breeding cyc [...]

by Stefan Hardy Lung  and Thomas Lung

Received: 30 November 2024;  Published: 14 April 2025;  doi: 10.21926/obm.geriatr.2502307

Cellular senescence (aging) is a physiological process that plays a role in tissue remodeling, wound healing, and embryogenesis. Prolonged senescence of cells can have detrimental effects and trigger a secretory phenotype (SASP, senescence-associated secretory phenotype), degenerative disorders, cancer, and age-related diseases. Suitable biomarkers and a range of different laboratory methods are used to investigate these complex relationships in vitro and in vivo. Since a universal biomarker for cell senescence has [...]

by Mohammad-Reza Ghasemi  , Maryam Mirahmadi  , Hadi Bayat  , Morteza Sheikhi Nooshabadi  , Sanaz Jamshidi  , Shadab Salehpour  , Reza Mirfakhraie  , Fatemeh Fazeli  , Mohammad Miryounesi  and Milad Gholami

Received: 22 November 2024;  Published: 14 April 2025;  doi: 10.21926/obm.genet.2502291

Knobloch Syndrome (KS) is a rare genetic disorder characterized by ocular abnormalities and central nervous system (CNS) defects, which are attributed to collagenopathy. The primary gene implicated in KS is COL18A1, which encodes the alpha chain of type XVIII collagen. This type of collagen functions as a proteoglycan, predominantly located in the basement membrane of human tissues. This study examined an Iranian female presenting with symptoms of horizontal nystagmus, strabismus, and suspected vision loss, with a [...]

by Recent Progress in Science and Engineering Editorial Office

Received: 07 April 2025;  Published: 11 April 2025;  doi: 10.21926/rpse.2502008

by Modupe Akintomide  , Xinyue Zhang  , Lota Iwuagwu  and Mary Ramos

Received: 03 October 2024;  Published: 10 April 2025;  doi: 10.21926/obm.geriatr.2502306

About 90% of people living with Alzheimer's disease and related dementias experience behavioral and psychological symptoms during the course of the disorder. Although extensive research exists on the roles of informal caregivers in dementia care, their abilities to manage behavioral symptoms and the resources they turn to for support remain understudied. This phenomenological study explored informal caregivers' experience, knowledge sources, and self-initiated strategies for managing behavioral symptoms of dementia [...]

by Fabiana Cristina Lima Barbosa  , Ana Carolina Teles de Aquino  , Marcos Paulo Gomes Mol  and Raphael Tobias de Vasconcelos Barros

Received: 16 October 2024;  Published: 10 April 2025;  doi: 10.21926/aeer.2502018

When addressing Healthcare Waste Management (HCWM), numerous factors play a crucial role in ensuring its safety and environmentally responsible handling within institutional processes. Recognizing this imperative, this study employed the Analytical Hierarchical Process (AHP) methodology to establish a comprehensive assessment of 10 primary criteria and 66 sub-criteria concerning the governance and operational aspects of Healthcare Waste Management. This evaluation was based on the insights of 14 specialists in the [...]

by Che Aishah Nazariah Ismail  , Nazlahshaniza Shafin  , Khairunnuur Fairuz Azman  , Idris Long  and Nor Syafinaz Yaakob

Received: 28 September 2024;  Published: 09 April 2025;  doi: 10.21926/obm.neurobiol.2502283

Chronic pain is a significant and global healthcare issue that hugely implies the quality of life and productivity of the affected individuals. It is challenging to treat and thus necessitates a deeper understanding of its underlying pathomechanisms to develop targeted interventions. Serotonin is one of the essential neurotransmitters involved in the propagation of pain signals through both ascending and descending pathways, acting via various receptor subtypes, including the 5-hydroxytryptamine receptor-6 (5-HT6R) [...]

by Sara Evans  , Ariba Moin  and Ashwini Arjuna

Received: 13 June 2024;  Published: 09 April 2025;  doi: 10.21926/obm.transplant.2502246

Varicella-zoster virus (VZV) significantly impacts the central and peripheral nervous systems, particularly in immunocompromised individuals. This case report details a rare presentation of VZV meningoencephalitis in a 42-year-old woman with interstitial lung disease and connective tissue disease undergoing lung transplant evaluation who presented with a thunderclap headache and a new-onset seizure. Despite normal initial MRI findings, further investigation with PCR of the cerebrospinal fluid (CSF) revealed the pre [...]

by Alessia Bartolacci  , Fabrizio Stocchi  , Vilberto Stocchi  and Sabrina Donati Zeppa

Received: 17 November 2024;  Published: 08 April 2025;  doi: 10.21926/rpn.2502007

In recent years, there has been an alarming increase in the incidence of inflammatory bowel disease (IBD), which includes both Crohn's disease (CD) and ulcerative colitis (UC), particularly in Western countries. This chronic condition is intricately linked to the composition and health of the gut microbiota (GM) — a complex community of microorganisms residing in the gastrointestinal (GI) tract. Despite extensive research, the underlying pathogenesis of IBD remains poorly understood, making it a wide area of invest [...]

by Ousman Bajinka  , Mamtuti Panneh  , Sang Mendy  , Amadou Barrow  , Haddy Bah  , Lamarana Jallow  , Jarry Jallow  , Kaddy Drammeh  , Kaddijatou Kah  , Oulimatou Lateef  , Mariama A Bah  , Isatou K Sillah  , Fatoumata Bah  , Nyima Ceesay  , Mariama Jaiteh  and Yurong Tan

Received: 31 August 2024;  Published: 08 April 2025;  doi: 10.21926/rpn.2502006

The adverse effects of maternal passive smoking during pregnancy on offspring health remain understudied in sub-Saharan Africa, particularly in The Gambia, where smoke-free regulations are limited. To determine the prevalence of maternal passive smoking (MPS) during pregnancy and investigate its associations with adverse pregnancy outcomes and offspring health complications in The Gambia. A cross-sectional study was conducted in February 2023 among 401 mothers with children under 5 years in urban and rural regions [...]

by Fatima A. M. Lino  , Kamal A. R. Ismail  , Waldir A. Bizzo  , Lucas A. N. da Silva  and João P. S. Veiga

Received: 23 September 2024;  Published: 07 April 2025;  doi: 10.21926/aeer.2502017

Urbanization driven by industrialization and population growth amplifies food consumption and reinforces the need for more fuels and energy. However, the expansion of biofuels can impose risks on long-term food security. This paper examines potential alternative crops for energy generation and food production, including those used by family farmers and their associations, to decentralize energy production and utilization as a crucial pillar of the global energy transition. Cassava, corn, and sugar beet are the chos [...]

by Lindsay E. Turgeon-Brown

Received: 19 November 2024;  Published: 07 April 2025;  doi: 10.21926/obm.icm.2502017

Teachers face at-work risk factors including compassion fatigue, burnout, dealing with violence, and a teacher shortage. A review of the literature shows that self-care can have positive benefits that mitigate and help to buffer these at-work risk factors This study examines teachers’ stories of self-care. The data suggests that self-care is a positive practice for teachers professionally and personally.