Management of Agitation, Delirium, and Catatonia in Intubated COVID-19 Patients: A Case Series & Rationale for Valproate Sodium Use During Extubation
Abstract
2009 14431
Management of Agitation, Delirium, and Catatonia in Intubated COVID-19 Patients: A Case Series & Rationale for Valproate Sodium Use During Extubationby
Abstract
The complete spectrum of neuropsychiatric effects of SARS-CoV-2 acute respiratory distress syndrome has yet to be fully appreciated, particularly in intubated patients. Manifestations including delirium and catatonia need to be considered in intubated COVID-19 patients. Medications known to exhibit neuroprotective effects, like valproate, can assist in agitation related to sedative withdrawal during extubation. This case series reports on the management of agitation, delirium, and catatonia in COVID-19 patients dur [...] 2009 14431 |
Hypnotic Responsiveness and Dissociation: A Multi-Variable AnalysisAbstract
Since Charcot [1], researchers and theorists have associated hypnotic responsiveness with dissociation. However, contemporary researchers have typically not documented impressive or statistically significant correlations between the most commonly used measure of dissociation, the Dissociative Experiences Scale-II [2, 3] and hypnotic responsiveness. We examined the ability of two measures of non-pathological dissociation, which have received scant attention in the hypnosis literature, the Wessex Dissociation Scale ( [...] 1978 14411 |
Using Acoustic Fields to Fabricate ECM-Based Biomaterials for Regenerative Medicine ApplicationsAbstract
Ultrasound is emerging as a promising tool for both characterizing and fabricating engineered biomaterials. Ultrasound-based technologies offer a diverse toolbox with outstanding capacity for optimization and customization within a variety of therapeutic contexts, including improved extracellular matrix-based materials for regenerative medicine applications. Non-invasive ultrasound fabrication tools include the use of thermal and mechanical effects of acoustic waves to modify the structure and function of extracell [...] 2355 14410 |
A Computational Simulation Technology for Specific Counting of Perinatal and Postnatal Human Tissue Stem Cells for Transplantation MedicineAbstract
Although tissue stem cells are essential for the maintenance, renewal, and repair of vertebrate organs and tissues, previously, the simple act of counting them has not been possible. For more than a half-century, progress in tissue stem cell research and medicine has been undermined by the lack of a means to determine tissue stem cell number. In particular, a major unmet need for stem cell transplantation medicine has been a way to quantify the specific dosage of tissue stem cell treatments. The counting problem pe [...] 2085 14368 |
A Review on Silk Fibers and Their Medical ApplicationsAbstract
This mini-compilation study included the chemical structure, mechanical, thermal, and dimensional properties of silk fiber, its production process, pre-treatment, and biomedical applications from various experimental studies, which are compiled and summarized. The silk fiber should have a degumming process before using biomedical applications. The 25% concentration for Na2CO3 in ethanol solution (80%) as a coagulant chemical with a salt such as LiB2 (9 M) at a temperature of 98°C for 45 minutes at pH between 6 [...] 2646 14365 |
Integrating Compassion into EMDR for PTSDby
Abstract
Post-traumatic stress disorder (PTSD) often involves feeling-states of shame and self-loathing. Traditional exposure-based treatments, which are effective for fear-based PTSD, are sometimes limited in effectiveness when working with these emotional experiences: clients with high levels of shame, guilt, or disgust may experience ‘blocks’ in processing when attempting eye movement desensitization and reprocessing (EMDR). Developed to help people who suffer from pervasive shame and self-attack, compassion focused ther [...] 2565 14364 |
Application of Finite Element Method for Mechanical Characterization of Wood and Reconstituted Lignocellulosic-Based Composites – A ReviewAbstract
Performance evaluations of wood and other lignocellulosic-based composites involve complex scenarios of several factors such as material heterogeneity and geometry that often leads to complicated, expensive, and time-consuming experimental procedures. Hence, the application of computational modeling and simulation is desirable to mitigate these biocomposites’ performance testing challenges. This review paper, therefore, presents an outlook on the finite element method (FEM) application in probing performance charac [...] 2118 14346 |
GAPcare: The Geriatric Acute and Post-Acute Fall Prevention Intervention for Emergency Department Patients – A Qualitative EvaluationAbstract
Background: Three million US emergency department (ED) visits occur for falls each year. The mortality of falls is increasing and only one fourth of older adults report their fall to their primary care provider, suggesting that valuable preventative opportunities are missed. A fall prevention intervention initiated in the ED immediately after a fall has the potential to reduce subsequent falls, but ED providers lack the time and resources to complete fall risk assessments on their patients. GAPcare, the Geriatric A [...] 3092 14300 |
The Role of Land Use Planning in Urban Transport to Mitigate Climate Change: A Literature Reviewby
Abstract
With the growing urbanisation phenomenon, ambitious policy interventions are needed to limit transport-related greenhouse gas emissions in urban areas. Cities are a predominant source of pollution, with urban transport contributing significantly to emissions. To address climate change, decision-makers must implement appropriate and effective mitigation instruments. This literature review focuses on the different approaches and supporting measures of urban transport land-use planning, such as mixed-used zoning plans [...] 1663 14296 |
The DPP4 Inhibitor Sitagliptin Increases Active GLP-1 Levels from Human Islets and May Increase Islet Cell Survival Prior to TransplantationAbstract
Background: One of the goals of clinical islet transplantation is to achieve a single-donor transplant that is dependent on obtaining enough quality β cell mass from one donor pancreas. Human islets are routinely cultured prior to transplantation, and pro-survival factors such as GLP-1 analogues have been reported to maintain β cell mass and survival. Interestingly, human islets may secrete GLP-1 and they also express the enzyme DPP4 that proteolytically cleaves GLP-1 into an inactive form. The aim of [...] 1502 14280 |
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