Table of Content

Open Access Case Report

Management of Agitation, Delirium, and Catatonia in Intubated COVID-19 Patients: A Case Series & Rationale for Valproate Sodium Use During Extubation

Received: 25 February 2021;  Published: 25 May 2021;  doi: 10.21926/obm.neurobiol.2102099

Abstract

The complete spectrum of neuropsychiatric effects of SARS-CoV-2 acute respiratory distress syndrome has yet to be fully appreciated, particularly in intubated patients. Manifestations including delirium and catatonia need to be considered in intubated COVID-19 patients. Medications known to exhibit neuroprotective effects, like valproate, can assist in agitation related to sedative withdrawal during extubation. This case series reports on the management of agitation, delirium, and catatonia in COVID-19 patients dur [...]

2009 14431

Open Access Original Research

Hypnotic Responsiveness and Dissociation: A Multi-Variable Analysis

Received: 18 February 2020;  Published: 11 May 2020;  doi: 10.21926/obm.icm.2002029

Abstract

Since Charcot [1], researchers and theorists have associated hypnotic responsiveness with dissociation. However, contemporary researchers have typically not documented impressive or statistically significant correlations between the most commonly used measure of dissociation, the Dissociative Experiences Scale-II [2, 3] and hypnotic responsiveness. We examined the ability of two measures of non-pathological dissociation, which have received scant attention in the hypnosis literature, the Wessex Dissociation Scale ( [...]

1978 14411

Open Access Review

Using Acoustic Fields to Fabricate ECM-Based Biomaterials for Regenerative Medicine Applications

Received: 22 March 2020;  Published: 21 July 2020;  doi: 10.21926/rpm.2003018

Abstract

Ultrasound is emerging as a promising tool for both characterizing and fabricating engineered biomaterials. Ultrasound-based technologies offer a diverse toolbox with outstanding capacity for optimization and customization within a variety of therapeutic contexts, including improved extracellular matrix-based materials for regenerative medicine applications. Non-invasive ultrasound fabrication tools include the use of thermal and mechanical effects of acoustic waves to modify the structure and function of extracell [...]

2355 14410

Open Access Research Article

A Computational Simulation Technology for Specific Counting of Perinatal and Postnatal Human Tissue Stem Cells for Transplantation Medicine

Received: 22 April 2020;  Published: 28 August 2020;  doi: 10.21926/obm.transplant.2003117

Abstract

Although tissue stem cells are essential for the maintenance, renewal, and repair of vertebrate organs and tissues, previously, the simple act of counting them has not been possible. For more than a half-century, progress in tissue stem cell research and medicine has been undermined by the lack of a means to determine tissue stem cell number. In particular, a major unmet need for stem cell transplantation medicine has been a way to quantify the specific dosage of tissue stem cell treatments. The counting problem pe [...]

2085 14368

Open Access Review

A Review on Silk Fibers and Their Medical Applications

Received: 12 December 2023;  Published: 15 March 2024;  doi: 10.21926/rpm.2401008

Abstract

This mini-compilation study included the chemical structure, mechanical, thermal, and dimensional properties of silk fiber, its production process, pre-treatment, and biomedical applications from various experimental studies, which are compiled and summarized. The silk fiber should have a degumming process before using biomedical applications. The 25% concentration for Na2CO3 in ethanol solution (80%) as a coagulant chemical with a salt such as LiB2 (9 M) at a temperature of 98°C for 45 minutes at pH between 6 [...]

2646 14365

Open Access Technical Note

Integrating Compassion into EMDR for PTSD

Received: 15 August 2023;  Published: 30 November 2023;  doi: 10.21926/obm.icm.2304058

Abstract

Post-traumatic stress disorder (PTSD) often involves feeling-states of shame and self-loathing. Traditional exposure-based treatments, which are effective for fear-based PTSD, are sometimes limited in effectiveness when working with these emotional experiences: clients with high levels of shame, guilt, or disgust may experience ‘blocks’ in processing when attempting eye movement desensitization and reprocessing (EMDR). Developed to help people who suffer from pervasive shame and self-attack, compassion focused ther [...]

2565 14364

Open Access Review

Application of Finite Element Method for Mechanical Characterization of Wood and Reconstituted Lignocellulosic-Based Composites – A Review

Received: 22 September 2022;  Published: 09 January 2023;  doi: 10.21926/rpm.2301003

Abstract

Performance evaluations of wood and other lignocellulosic-based composites involve complex scenarios of several factors such as material heterogeneity and geometry that often leads to complicated, expensive, and time-consuming experimental procedures. Hence, the application of computational modeling and simulation is desirable to mitigate these biocomposites’ performance testing challenges. This review paper, therefore, presents an outlook on the finite element method (FEM) application in probing performance charac [...]

2118 14346

Open Access Research Article

GAPcare: The Geriatric Acute and Post-Acute Fall Prevention Intervention for Emergency Department Patients – A Qualitative Evaluation

Received: 21 August 2019;  Published: 10 October 2019;  doi: 10.21926/obm.geriatr.1904078

Abstract

Background: Three million US emergency department (ED) visits occur for falls each year. The mortality of falls is increasing and only one fourth of older adults report their fall to their primary care provider, suggesting that valuable preventative opportunities are missed. A fall prevention intervention initiated in the ED immediately after a fall has the potential to reduce subsequent falls, but ED providers lack the time and resources to complete fall risk assessments on their patients. GAPcare, the Geriatric A [...]

3092 14300

Open Access Review

The Role of Land Use Planning in Urban Transport to Mitigate Climate Change: A Literature Review

Received: 13 May 2022;  Published: 26 August 2022;  doi: 10.21926/aeer.2203033

Abstract

With the growing urbanisation phenomenon, ambitious policy interventions are needed to limit transport-related greenhouse gas emissions in urban areas. Cities are a predominant source of pollution, with urban transport contributing significantly to emissions. To address climate change, decision-makers must implement appropriate and effective mitigation instruments. This literature review focuses on the different approaches and supporting measures of urban transport land-use planning, such as mixed-used zoning plans [...]

1663 14296

Open Access Research Article

The DPP4 Inhibitor Sitagliptin Increases Active GLP-1 Levels from Human Islets and May Increase Islet Cell Survival Prior to Transplantation

Received: 12 March 2019;  Published: 26 June 2019;  doi: 10.21926/obm.transplant.1902069

Abstract

Background: One of the goals of clinical islet transplantation is to achieve a single-donor transplant that is dependent on obtaining enough quality β cell mass from one donor pancreas. Human islets are routinely cultured prior to transplantation, and pro-survival factors such as GLP-1 analogues have been reported to maintain β cell mass and survival. Interestingly, human islets may secrete GLP-1 and they also express the enzyme DPP4 that proteolytically cleaves GLP-1 into an inactive form. The aim of [...]

1502 14280

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