by Laxminarayan Sahoo  , Payal Murmu  , Mohan Krishna Ghanta  and LVKS Bhaskar

Received: 28 June 2025;  Published: 30 October 2025;  doi: 10.21926/obm.genet.2504314

Ebstein's anomaly (EA) is a rare form of congenital heart disease (CHD), characterized by abnormal cardiac anatomy involving a defective tricuspid valve (TV), resulting in tricuspid regurgitation (TR) and cyanosis. EA is represented in different case scenarios with varying degrees of complexity across various age groups. It usually affects 0.2-0.7 out of 10,000 live births and accounts for 0.3%-0.6% of all CHD cases. While its occurrence is mainly sporadic, evidence from multiple studies suggests that EA can be ass [...]

by Robert B. Diller  , Robert G. Audet  , Mediha Gurel  , Eric E. Lee  , Aaron J. Tabor  , Peter McFetridge  and Robert S. Kellar

Received: 25 September 2019;  Published: 09 June 2020;  doi: 10.21926/obm.transplant.2002112

Mesenchymal Stromal/Stem Cells (MSCs) were originally discovered in the 1970s. MSCs are considered a multipotent population that retain tri-lineage differentiation. These cells can be sourced from a variety of tissues, including bone marrow, adipose, molar pulp, and birth tissues. Historically varying definitions of MSCs have existed, but in 2006, the International Society for Cellular Therapy (ISCT) set forth a standardized, minimal criteria for MSCs, including plastic adherence, differentiation into osteoblasts, [...]

by CT Valliappan  , J Joyson Joe Asir  , V Subashri  , V Vaishnavi  and I Anand Sherwood

Received: 28 December 2020;  Published: 27 April 2021;  doi: 10.21926/rpm.2102014

Furcal perforation management in root canal retreatment is often challenging as the outcome of the perforation sealing depends on several parameters. The recent introduction of several bioactive cements and magnification systems has made the sealing of perforations easier and the outcome more predictable. This study highlights the clinical outcomes of furcal perforation management in root canal retreatment using biodentine.

by James Farag  and Silvana Marasco

Received: 13 February 2019;  Published: 08 April 2019;  doi: 10.21926/obm.transplant.1902060

Left ventricular assist devices (LVADs) improve quality of life in end-stage heart failure patients but a frequent complication is Right heart failure (RHF) causing significant morbidity and mortality. This review article discusses key issues that need to be considered in the assessment and clinical management of RHF in LVAD patients including the use of Right Ventricle (RV) support devices and off-label LVADs as temporary or permanent RV support.

by Maria Neve Ombra  , Filomena Nazzaro  and Florinda Fratianni

Received: 30 March 2023;  Published: 07 June 2023;  doi: 10.21926/rpn.2302008

Edible wild plants are a largely available food at no cost and an emblem of sustainability. Among the numerous varieties of edible wild plants, purslane (Portulaca oleracea L.) and common mallow (Malva sylvestris L.) are good sources of healthful bioactive compounds. Therefore, there is a growing interest in their consumption for health-related nutritional and sustainable perspectives. Fresh durum wheat tagliatelle fortified with dried and pulverized leaves of mallow or purslane at two distinct percentages of integ [...]

by Zena Aldridge  and Karen Harrison Dening

Received: 19 September 2019;  Published: 18 October 2019;  doi: 10.21926/obm.geriatr.1904081

The population of the United Kingdom is ageing. In 2017 approximately 18% of the UK population were aged 65 years or over and projected to grow to almost 21% by 2027 according to the Office of National Statistics. Increased age is the greatest risk factor for developing dementia. It is estimated that there are 850,000 people living with dementia in the UK and if current figures relating to incidence and prevalence are realised, this will increase to 1 million people by 2025 and 2 million by 2051. The National Healt [...]

by Oyovwi Mega Obukohwo  , Oyelere Abosede Oreoluwa  , Odewale O. Comfort  and Afolabi Opeyemi Olanike

Received: 24 March 2024;  Published: 20 June 2024;  doi: 10.21926/obm.genet.2402246

Infertility affects millions globally, with 10-15% of couples experiencing unexplained cases. Despite advancements in medicine, the cause remains unknown, causing emotional distress. Recent research suggests a genetic basis for this issue. This review aims to provide a better understanding of the underlying genetic factors contributing to unexplained infertility and potentially identify genetic markers that could aid in the diagnosis and treatment of this condition. A literature review was conducted to understand t [...]

by Joseph P. Green  , Steven Jay Lynn  , Olivia J. Green  , Victoria R. Bradford  and Rouhangiz Rasekhy

Received: 18 February 2020;  Published: 11 May 2020;  doi: 10.21926/obm.icm.2002029

Since Charcot [1], researchers and theorists have associated hypnotic responsiveness with dissociation. However, contemporary researchers have typically not documented impressive or statistically significant correlations between the most commonly used measure of dissociation, the Dissociative Experiences Scale-II [2, 3] and hypnotic responsiveness. We examined the ability of two measures of non-pathological dissociation, which have received scant attention in the hypnosis literature, the Wessex Dissociation Scale ( [...]

by Nancy Poirier  , Serge Beaulieu  , Sybille Saury  and Sonia Goulet

Received: 24 July 2018;  Published: 05 November 2018;  doi: 10.21926/obm.icm.1804028

Background: This study investigated variations in psychic and somatic anxiety during and after completion of MBCT compared to baseline in patients diagnosed with BD. Secondary variables considered were sleep quality and quality of life, as well as depressive and manic symptoms. Methods: HAMD-29, HAMD-7 and YMRS were administered at baseline (n=34), and every two weeks until the end of the eight-week program. PSQI (n=22) and Q-LES-Q-SF (n=29) were also administered at pre, mid- and post- MBCT assessments. Results: T [...]

by Amrin Ahmed  , Alixe Ménard  , Alison C Novak  , Nancy Edwards  and Sarah Fraser

Received: 27 May 2024;  Published: 28 August 2024;  doi: 10.21926/obm.geriatr.2403286

Older adults are disproportionately susceptible to hospitalizations and fatalities due to stair-related falls. While many intrinsic risk factors, such as mobility and vision, may increase the likelihood of falls on stairs, features of the stairs that increase the risk of falls are understudied. This study aimed to capture older adults’ perspectives of stair falls, as well as introduce the Safer Steps app and explore its feasibility in this population. This m-health technology was designed to gather data on st [...]