by Kristy Lui  , Darlene Yee-Melichar  and Emiko Takagi

Received: 31 October 2018;  Published: 08 April 2019;  doi: 10.21926/obm.geriatr.1902046

This research review sought to examine the patterns of engagement in advance care planning (ACP) and utilization of end-of-life (EoL) care treatment services including, but not limited to hospice care, in distinct older Asian American ethnic groups. The review of existing research suggested evidence that empirical studies about different older subpopulations of Asian Americans remains scarce. This research analysed 30 small-scale studies on older Asian Americans’ attitudes and engagement in EoL care planning. The r [...]

by Khalid Nawaz  , Iqra  , Muneeb Ullah  , Jin-Wook Yoo  , Umme Aiman  , Madiha Ghazanfar  and Muhammad Naeem

Received: 21 June 2024;  Published: 10 January 2025;  doi: 10.21926/rpn.2501002

The persistent inflammation of the intestinal mucosa is the main characteristic of inflammatory bowel disease (IBD), a lifelong illness that affects people of both genders. The exact etiology is still undefined while previously it was attributed to genetic components. Later, it was investigated that the environment has an equal effect on the development of IBD encompassing both Crohn’s disease (CD) and Ulcerative colitis (UC). Among environmental risk factors linked to IBD, diet, notably the transition toward the W [...]

by James Farag  and Silvana Marasco

Received: 13 February 2019;  Published: 08 April 2019;  doi: 10.21926/obm.transplant.1902060

Left ventricular assist devices (LVADs) improve quality of life in end-stage heart failure patients but a frequent complication is Right heart failure (RHF) causing significant morbidity and mortality. This review article discusses key issues that need to be considered in the assessment and clinical management of RHF in LVAD patients including the use of Right Ventricle (RV) support devices and off-label LVADs as temporary or permanent RV support.

by Renly Dutton  , Frank Abdi  , Levon Minnetyan  and James L. Sherley

Received: 22 April 2020;  Published: 28 August 2020;  doi: 10.21926/obm.transplant.2003117

Although tissue stem cells are essential for the maintenance, renewal, and repair of vertebrate organs and tissues, previously, the simple act of counting them has not been possible. For more than a half-century, progress in tissue stem cell research and medicine has been undermined by the lack of a means to determine tissue stem cell number. In particular, a major unmet need for stem cell transplantation medicine has been a way to quantify the specific dosage of tissue stem cell treatments. The counting problem pe [...]

by Nancy Poirier  , Serge Beaulieu  , Sybille Saury  and Sonia Goulet

Received: 24 July 2018;  Published: 05 November 2018;  doi: 10.21926/obm.icm.1804028

Background: This study investigated variations in psychic and somatic anxiety during and after completion of MBCT compared to baseline in patients diagnosed with BD. Secondary variables considered were sleep quality and quality of life, as well as depressive and manic symptoms. Methods: HAMD-29, HAMD-7 and YMRS were administered at baseline (n=34), and every two weeks until the end of the eight-week program. PSQI (n=22) and Q-LES-Q-SF (n=29) were also administered at pre, mid- and post- MBCT assessments. Results: T [...]

by Maurizio Salvadori  and Aris Tsalouchos

Received: 19 January 2020;  Published: 03 February 2020;  doi: 10.21926/obm.transplant.2001097

Immunosuppressive therapy in renal transplantation is divided into two phases as induction and maintenance therapy. Induction therapy is an intense immunosuppressive therapy administered at the time of kidney transplantation to reduce the risk of acute allograft rejection. In general, induction immunosuppressive strategies utilized by kidney transplant centers fall in one of the two categories. One approach relies upon high doses of conventional immunosuppressive agents, while the other uses antibodies directed aga [...]

by Robert J. Brent

Received: 31 July 2019;  Published: 10 October 2019;  doi: 10.21926/obm.geriatr.1904079

Background: The 2018 Alzheimer's Disease Facts and Figures special report includes two new guidelines for measuring dementia symptoms. The first requires that a biomarker (biological factor) be added to a doctor's clinical judgment of the cause of symptoms when determining whether dementia is present. The second involves identifying four stages of dementia: normal cognition, preclinical, MCI and dementia. Now only those with defining brain pathologies and significant symptoms will be judged to be persons with stage [...]

by Giuseppe Cocco  and Philipp R. Amiet

Received: 16 January 2021;  Published: 28 July 2021;  doi: 10.21926/obm.geriatr.2103178

Atrial fibrillation is very common in most old patients who need an adapted therapy due to their comorbidities. Before initiating an antiarrhythmic therapy, possible adverse effects, especially iatrogenic proarrhythmia, and extracardiac side-effects, must be considered. In geriatric patients with atrial fibrillation, heart rate control is the most frequent therapy. Oral anticoagulation plays a vital role in the therapy, but anticoagulation in old patients, who had a bleeding or stroke event, is challenging. Availab [...]

by Suzie Jokic  , Nicole Jacqueline Albrecht  and Sue Erica Smith

Received: 15 July 2018;  Published: 23 January 2019;  doi: 10.21926/obm.icm.1901004

Background: Adult learners often engage in formal education because they want to create changes in their lives and are determined to succeed in their chosen field. However, they also come with emotional "baggage" of early educational experiences, frequently have to deal with a multitude of competing demands, have financial strain, may face a lack of support, illness and/or injury. In addition, they are often dealing with the challenges of unfamiliar academic work, competing deadlines and initially lack basic academ [...]

by Emma G. Norris  , Diane Dalecki  and Denise C. Hocking

Received: 22 March 2020;  Published: 21 July 2020;  doi: 10.21926/rpm.2003018

Ultrasound is emerging as a promising tool for both characterizing and fabricating engineered biomaterials. Ultrasound-based technologies offer a diverse toolbox with outstanding capacity for optimization and customization within a variety of therapeutic contexts, including improved extracellular matrix-based materials for regenerative medicine applications. Non-invasive ultrasound fabrication tools include the use of thermal and mechanical effects of acoustic waves to modify the structure and function of extracell [...]