by Deborah R. Simkin  and L. Eugene Arnold

Received: 06 April 2020;  Published: 19 October 2020;  doi: 10.21926/obm.icm.2004040

Teen depression and suicide rates have risen despite conventional treatments. This article reviews adjunctive interventions that may improve outcomes. A search of the National Library of Medicine database used tailored searches with combinations of specific terms. Modern lifestyle is associated with increased inflammation and pro-inflammatory cytokines leading to, for instance, hyperactivation of the hypothalamic-pituitary-adrenal axis, which promotes depression. Inflammation also increases oxidative stress, leadin [...]

by Christopher H. Vane  , Alexander W. Kim  , Darren Beriro  , Mark R. Cave  , Stephen R. Lowe  , Raquel A. Lopes dos Santos  , Antonio M. P. J. Ferreira  , Christopher Collins  , C. Paul Mathanail  and Vicky Moss-Hayes

Received: 05 March 2021;  Published: 28 May 2021;  doi: 10.21926/aeer.2102012

Total organic carbon (TOC), black carbon (BC), total petroleum hydrocarbons (TPH), polycyclic aromatic hydrocarbons (PAH) and polychlorinated biphenyls (PCB) were determined in 73 surface (0-2 cm) and subsurface (5-20 cm) soil samples taken from a 142 km2 area in Central London, UK. Soils were assessed to provide a baseline chemistry for site owners, developers, occupiers and regulators involved in understanding the potential risk to human health and the environment. TOC range was 1.75-11.85 % (mean 5.82 %), BC 3.7 [...]

by Mary P Galea  , Natasha van Zyl  and Aurora Messina

Received: 02 October 2020;  Published: 29 December 2020;  doi: 10.21926/obm.neurobiol.2004075

Spinal cord injury (SCI) leads to an immediate loss of sensory and motor function below the level of injury mostly affecting people in the prime of life. In addition to the primary injury there is accumulating neurophysiological and histological evidence of dysfunction in the peripheral nerves, not related to direct damage from the primary injury, which exacerbates muscle wasting, and contributes to further functional loss and poor recovery. Among the potential contributing factors are systemic inflammation, and mo [...]

by Annie Keleher  , Paul Dargusch  and Genia Hill

Received: 13 January 2022;  Published: 15 April 2022;  doi: 10.21926/aeer.2202013

With scientific consensus on climate change and growing public concern, firms are recognising the multiple risks associated with inaction on their Greenhouse Gas (GHG) emissions. The Information and Communications Technology (ICT) and Entertainment & Media (E&M) sectors provide essential communications services, that are foundational for much of the modern world's social and economic systems. The ICT sector has already demonstrated success in innovations that enable emissions reductions. At the same tim [...]

by Aditya Sharma  , Opeyemi Bello  , Catalin Teodoriu  and Hamidreza Karami

Received: 15 February 2021;  Published: 30 June 2021;  doi: 10.21926/jept.2102030

The Industry 4.0 is here, and advanced technologies are widely available for domains such oil and gas which are traditionally slow in adopting extreme new technologies. This paper presents the design architecture and implementation of effective data acquisition (DAQ) and monitoring system applied to an experimental sucker rod pumping unit for both event occurrence and educational purpose using latest technological advancements and industry 4.0 principles. The designed framework allows control and monitoring of anal [...]

by Onix Cantres-Fonseca  , Shambhu Aryal  , Christopher King  and Steven D. Nathan

Received: 25 May 2023;  Published: 20 February 2024;  doi: 10.21926/obm.transplant.2401207

Chronic allograft dysfunction (CLAD) is one of the leading causes of death after lung transplantation [1]. CLAD is a progressive and irreversible decline in lung function after transplant, manifested as an obstructive, restrictive, or mixed ventilatory impairment without any identifiable etiology as infection or acute rejection. Multiple risk factors have been associated with this condition. Despite its significant effect on the mortality of transplanted patients, there is still a lack of powerfully effective thera [...]

by Shehab Mohamed  , Davide Tosi  , Sara Pieropan  , Andrea Cara  , Giovanni Caffarena  , Giorgio Alberto Croci  and Lorenzo Rosso

Received: 01 July 2020;  Published: 21 December 2020;  doi: 10.21926/obm.transplant.2004129

Pulmonary transplantation (LuTx) is established as a treatment option for patients with end-stage lung diseases, such as chronic obstructive pulmonary disease, cystic fibrosis, interstitial lung disease, and pulmonary arterial hypertension. Acute rejection and infection are implicated as potential risk factors in developing complications such as bronchiolitis obliterans syndrome (BOS) and chronic rejection, leading to high morbidity and mortality rates after the LuTx. Thus, surveillance procedures after transplanta [...]

by Joseph V. Pergolizzi  , Jo Ann LeQuang  , Peter Magnusson  and Giustino Varrassi

Received: 11 April 2021;  Published: 12 July 2021;  doi: 10.21926/obm.icm.2103021

Traditional, complementary, and integrative medicine (TCIM) approaches to COVID-19 represent a paradigm shift from Western medicine, in that TCIM emphasizes prevention, encouraging wellness, and supporting health and recovery. A wide range of TCIM approaches exist: whole medical systems (such as traditional Chinese medicine), mind-body approaches, biological therapies, body-based treatments, and energy therapies. TCIM is used to help people resist infection, but people with moderate to severe COVID-19 symptoms ofte [...]

by Zena Aldridge  and Karen Harrison Dening

Received: 19 September 2019;  Published: 18 October 2019;  doi: 10.21926/obm.geriatr.1904081

The population of the United Kingdom is ageing. In 2017 approximately 18% of the UK population were aged 65 years or over and projected to grow to almost 21% by 2027 according to the Office of National Statistics. Increased age is the greatest risk factor for developing dementia. It is estimated that there are 850,000 people living with dementia in the UK and if current figures relating to incidence and prevalence are realised, this will increase to 1 million people by 2025 and 2 million by 2051. The National Healt [...]

by XinRan Quan  and Marica Bakovic

Received: 21 December 2020;  Published: 21 July 2021;  doi: 10.21926/obm.geriatr.2103176

Neurodegenerative diseases (NDs) are a diverse group of neuropathological diseases that are currently incurable due to the irreversible neuronal loss. At the present rate of the world population growth, it is projected that the number of ND cases will double by the year of 2050. With treatments only available for symptom management and relief, disease prevention may yield significant benefits. Recently, there had been association drawn between the disruption of phospholipid (PL) homeostasis and the progression of N [...]