by Anastasia Gyimah  , Chinyere Ajayi  and Peggy Mulongo

Received: 23 January 2025;  Published: 17 July 2025;  doi: 10.21926/obm.icm.2503031

Unaccompanied asylum-seeking children (UASC) are amongst the most vulnerable populations worldwide, facing significant psycho-social and mental health challenges influenced by pre-migration, migration, and post-migration experiences. This narrative review examines the structural, legal, and practical factors affecting UASC, focusing on their lived experiences within the UK’s asylum system. Key areas explored include trauma caused by forced migration (pre-, during and post-migration), ethical dilemmas surrounding ag [...]

by Duc Duy Huynh  , Hoang Phuc Nguyen  , Tran Quoc Thang Nguyen  , Thi Hong Nga Pham  , Quan Anh Pham  , Thi Van Anh Duong  , Van Huong Hoang  , Xuan Tien Vo  and Vinh Tien Nguyen

Received: 29 May 2025;  Published: 24 September 2025;  doi: 10.21926/rpm.2503015

Beverage bottle caps are usually made from two primary materials: PP and HDPE. In this study, the evaluation criteria were the unnotched impact toughness and the microstructure of PP/HDPE/EVA samples produced by injection molding. The samples were tested according to ASTM D256. PP/HDPE/EVA blends were prepared with various ratios: 47.5/47.5/5, 45/45/10, 42.5/42.5/15, 40/40/20, and 37.5/37.5/25. The results showed that adding EVA to the PP/HDPE blend significantly increased the unnotched impact toughness: from 84.03 [...]

by OBM Transplantation Editorial Office

Received: 03 January 2024;  Published: 04 January 2024;  doi: 10.21926/obm.transplant.2401205

The editors of OBM Transplantation would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to t [...]

by Lucia Urbanová  , Silvia Farkasova  , Ivana Speváková  , Matúš Kyseľ  , Veronika Šimora  , Miroslava Kacaniova  and Jana Žiarovská

Received: 21 May 2024;  Published: 26 September 2024;  doi: 10.21926/obm.genet.2403263

Medicinal plants have been a part of human life from a very early age. In the field of plant genetics, they are still widely investigated for their genomic variability. This study used two DNA marker techniques to obtain polymorphic profiles in selected species from Lamiaceae. Both are based on the variability of plant genes that code for allergens - BBAP (Bet v 1-Based Amplicon Polymorphism) and PBAP (Profilin-Based Amplicon Polymorphism). Variability of Bet v 1 homologues within individual genomes showed similari [...]

by Hela Mhiri  , Manel Chalbi  , Nesrine Dridi  , Faten Ouled Brahim  and Med Ali Chemli

Received: 06 April 2025;  Published: 24 June 2025;  doi: 10.21926/obm.genet.2502297

We report the case of a 3-year-old girl from a consanguineous marriage, initially diagnosed with vitamin D deficiency–associated periodontitis following early tooth mobility. Despite supplementation, her condition worsened with the onset of palmoplantar hyperkeratosis. Further investigations revealed the diagnosis of Papillon-Lefèvre Syndrome (PLS), a rare genetic disorder causing severe periodontitis and palmoplantar keratosis. The patient was managed with vitamin D supplementation, dental extractions, and a remov [...]

by Manish Suryapalam  , Jay Kanaparthi  , Shineui Kim  , Pedram Shafiei-Jahani  , Armeen Barghi  and Mohammed Kashem

Received: 10 November 2024;  Published: 11 June 2025;  doi: 10.21926/obm.transplant.2502252

While heart transplantation is increasingly performed in the United States for elderly patients, survival outcomes have primarily been analyzed in single-center studies. The few existing long-term studies have indicated no difference in HTx outcomes between patients ≥70 years and 60-69 years age, but these studies only assessed to 5-years post-transplant and included data from the 1980-90s, introducing significant variance due to poorer outcomes in that era. We analyzed the UNOS database from 1987-2020, stratified [...]

by Robert Marx

Received: 24 April 2024;  Published: 20 August 2024;  doi: 10.21926/obm.icm.2403047

It is an axiomatic in secular mindfulness that to become present is to direct attention away from thinking to physical sensation. While this can be a useful strategy to manage depressive rumination, as an automatic default position, it risks demonising our fundamental human capacity to purposefully think about the causes of suffering and how to reduce it. Many approaches within Mahayana Buddhism in particular explicitly use reflection on key ideas as necessary pre-requisites to meditation, and in these traditions, [...]

by Pierre-Yves Maillard  , Sima Tokajian  , Marie Vilaire-Meunier  , Charbel Al Khoury  , Cybel Mehawej  , Eliane Chouery  , Marie-Anne Caillaud  , Louise Maillebouis  , Ines Ben Smida  , Sophie Durand  , Aimé Ravel  , Cecile Cieuta-Walti  , Marie-Noëlle Ungeheuer  , Clotilde Mircher  and André Mégarbané

Received: 05 October 2024;  Published: 03 July 2025;  doi: 10.21926/obm.genet.2503300

To investigate the potential impact of the additional chromosome 21 on the gut microbiome in patients with Down syndrome (DS), two monozygotic (MZ) and two dizygotic (DZ) twin pairs discordant for DS were studied. Whole-genome shotgun sequencing was conducted to analyze the taxonomic and functional profiles of the gut microbial community in the twins and assess whether the gut microbiome composition influences the development of psychological pathologies. Sequencing generated a total of 2,338,132 reads, combined ac [...]

by Jessica Palacios  , Odin Ramírez-Fernández  and Esmeralda Zuñiga-Aguilar

Received: 22 August 2024;  Published: 07 March 2025;  doi: 10.21926/obm.transplant.2501240

Tissue engineering offers alternatives when it comes to health problems such as trauma or pathologies. One of them is the scaffolds, which provide a favorable architecture, mechanics, and biocompatibility for the fixation of cells. Therefore, the following research aims to design and simulate scaffolds with mixed geometric structures to create a hybrid architecture for osseointegration while maintaining structural properties similar to subchondral bone and hyaline cartilage. Three scaffolds were designed for this p [...]

by Michael Y. Shino  , Francisco Javier Ibarrondo  , Jesse L. Clark  , Adreanne Rivera  , Marlene Florian  , Allison Ramsey  , Ariss Derhovanessian  , Rajan Saggar  , Olawale O. Amubieya  , Grant Turner  , Joanna M. Schaenman  , Pryce T. Gaynor  , Omer E. Beaird  , Ashrit Multani  , Reshma M. Biniwale  , Murray H. Kwon  , Christos J. Petropoulos  , Yolanda Lie  , Terri Wrin  , Amparo L. Figueroa  , Brett Leav  , Zelalem Endale  , Kate Anteyi  , Jacqueline M. Miller  , Abbas Ardehali  , David M. Sayah  , David Elashoff  , John A. Belperio  , Otto O. Yang  and S. Sam Weigt

Received: 16 August 2024;  Published: 20 November 2024;  doi: 10.21926/obm.transplant.2404227

Higher-dose mRNA booster vaccines have not been well studied for transplant recipients. This study evaluated the safety, reactogenicity and immunogenicity of higher dose mRNA-1273 booster vaccines among lung transplant recipients (LTRs). This phase 1/2 open-label randomized clinical trial of higher-dose mRNA-1273 booster vaccination enrolled nineteen adult LTRs into the 50 µg (n = 8) vs. 100 µg (n = 11) groups before enrollment was terminated due to the availability of the bivalent mRNA-1273.222 vaccine [...]