Table of Content

Open Access Review

The Cellular Mechanism of Aging as Programmed Epigenetic Phenomenon: From Hypothesis to Scientific Evidence

Received: 04 December 2024;  Published: 10 September 2025;  doi: 10.21926/obm.geriatr.2503325

Abstract

There is a main difference between theories explaining aging as an adaptive phenomenon that is determined and modulated by genes (i.e., the result of a specific “program”) and theories explaining aging as a non-adaptive phenomenon caused by the accumulation of random degenerative events. In fact, for adaptive theories, a genetically determined and modulated program determining aging is indispensable, while for non-adaptive theories, such a program cannot exist. However, there appears to be strong evidence to suppor [...]

982 4186

Open Access Research Article

Lanthanum Uptake and Distribution in Agricultural and Wild Plants: Insights from Greenhouse and Field Studies in Uncontaminated Soils

Received: 24 March 2025;  Published: 08 July 2025;  doi: 10.21926/rpse.2503012

Abstract

Lanthanum (La) is widely used in various fields. As a consequence, it can accumulate in soil and thus pose a potential hazard to the environment, including a decrease of plant biomass and chlorophyll content. To date, most experimental studies on the biogeochemistry of La have focused on toxic effects resulting from its accumulation in plants growing in La-contaminated areas, while the behavior of La in plants growing in uncontaminated soils has been the subject of much less research. The primary objectives of this [...]

889 4180

Open Access Original Research

The Multiple, Embodied Positive Effects of a Community-Based Aerial Sling Class: Improved Body Schema, Fitness, Mental Health, and Diet

Received: 06 April 2025;  Published: 17 July 2025;  doi: 10.21926/obm.icm.2503032

Abstract

Contrary to the dominant ultra-cognitive approach in public health whereby only thought processes are supposed to link to action (e.g., physical activity) and health, in this research an embodied (body-mind unison) philosophy was examined by showcasing the importance of holistic and performative movement experiences to health and well-being. Specifically, the purpose of this study was to comprehensively examine the interrelated, multiple, and embodied benefits of a community-based aerial sling class (“Flow”) on bod [...]

758 4119

Open Access Original Research

Hassles during the First Year of Medical School: Can a Student Wellness Program Make a Difference?

Received: 14 March 2024;  Published: 27 September 2024;  doi: 10.21926/obm.icm.2403057

Abstract

Acute stress during medical school affects medical student well-being. The objective of the current study was to examine the influence of a holistic, school-sponsored student wellness program (SWP) on acute stress during the first year of medical school. First-year medical students attending two osteopathic medical schools participated, one school with a holistic student wellness program (SWP group) and one without an organized student wellness program (Control group). The SWP was founded on osteopathic philosophy [...]

636 4113

Open Access Editorial

Catalysis, Meet the Machine: From Models to Meaning

Received: 25 June 2025;  Published: 27 June 2025;  doi: 10.21926/cr.2502005

835 4111

Open Access Short Communication

Therapeutic Termination of Pregnancy and Paternal Mental Outcomes

Received: 26 December 2023;  Published: 13 June 2024;  doi: 10.21926/obm.icm.2402034

Abstract

Therapeutic termination of pregnancy (TToP) is performed for maternal health risks or severe fetal malformations. Research focuses on women's psychopathological outcomes after TToP, noting that 10-22% of women experience psychiatric disorders, especially depressive symptoms and post-traumatic stress disorder (PTSD). However, little is known about paternal mental outcomes. This study analyzed biological fathers' mental health at a 1-year follow-up after TToP. Results indicate biological fathers show no alarming psyc [...]

781 4045

Open Access Original Research

Eryngium carlinae Extract and Exercise Improve Blood Lipid Profile and Skeletal Muscle Function in Obese Rats

Received: 08 January 2024;  Published: 10 July 2024;  doi: 10.21926/obm.icm.2403040

Abstract

An excess of adipose tissue characterizes obesity; it is associated with complications such as diabetes and cardiovascular diseases due to an alteration in the lipid profile; this condition affects all tissues; even skeletal muscle is the most affected, causing its malfunction and bringing more significant consequences. Exercise has been described as one of the best treatments to combat obesity. At the same time, E. carlinae is a plant proven to have lipid-lowering and hypoglycemic effects, improving the function o [...]

822 4045

Open Access Editorial

Acknowledgement to Reviewers of OBM Neurobiology in 2023

Received: 03 January 2024;  Published: 02 January 2024;  doi: 10.21926/obm.neurobiol.2401204

Abstract

The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the [...]

825 4045

Open Access Original Research

Serum Shock Enhances Endogenous Melatonin Production and Mitochondrial Gene Regulation in U87-MG Glioblastoma Cells

Received: 14 March 2025;  Published: 07 July 2025;  doi: 10.21926/obm.genet.2503301

Abstract

Glioblastoma (GBM) is the most aggressive primary brain tumor, with a poor prognosis despite advancements in understanding its biology. Melatonin, a key regulator of metabolism and cellular homeostasis, is known for its neuroprotective and anti-cancer properties. While traditionally linked to pineal gland secretion, emerging evidence suggests that glioblastoma cells can produce melatonin within their mitochondria. This study investigates whether serum shock can influence endogenous melatonin production and mitochon [...]

918 4038

Open Access Original Research

Digital Technology and Brain Development among Entrepreneurial Ambitions

Received: 20 October 2024;  Published: 25 February 2025;  doi: 10.21926/obm.neurobiol.2501271

Abstract

Brain development (BD) is an important factor. To effectively enhance BD, institutions employ digital tools, technology, and innovative digital competencies to improve students’ entrepreneurial ambitions. The present paper examines the role of digital technology in developing BD among entrepreneurial ambitions in Egypt. The study modes are quantitative and cross-sectional to collect data from the entrepreneurial aspirations of Egyptian universities where business, management, economics, and commerce students [...]

692 4038

TOP