Table of Content

Open Access Original Research

The Symptomatic Expression in Chinese Patients with Suspected COVID-19 Omicron Variant Infection: A Clinical Case Registry Study

Received: 29 February 2024;  Published: 29 July 2024;  doi: 10.21926/obm.icm.2403043

Abstract

Little systematic research has been conducted into the symptomatic expression of COVID-19 infections in patients. It is known that symptomatic expression varies between patients, but the nature and extent of this variability is poorly understood. This paper elaborates on the symptoms reported by Chinese patients infected with COVID-19 during the Omicron wave, and compares this with available data from other countries. This was an observational clinical case registry study of Chinese patients with suspected Omicron [...]

784 4456

Open Access Review

The Independence Principle - A Neglected Feature of the Hodgkin Huxley Legacy

Received: 19 May 2024;  Published: 17 March 2025;  doi: 10.21926/obm.neurobiol.2501278

Abstract

The legacy of Hodgkin and Huxley rests on their squid giant axon studies, which were summarised in an empirical model of impressive predictive power that successfully quantified the permeability changes of excitable membranes and accurately reconstructed the action potential. Hodgkin and Huxley applied the independence principle to their experimental data in order to reveal potential mechanism(s) of trans-membrane ion movements. This was motivated by their lack of information on the manner in which ions crossed the [...]

824 4455

Open Access Review

Platelets as Regenerative Cells, Hundreds of Opportunities in Sight

Received: 21 May 2024;  Published: 13 August 2024;  doi: 10.21926/obm.transplant.2403223

Abstract

Platelets were the last to be discovered of the three formed blood elements. Several scientists have been interested in them, recognizing them as cells other than leukocytes and erythrocytes. Its job in hemostasis and thrombosis is currently known. Platelets contain growth factors and secrete cytokines, which have roles in inflammation and tissue regeneration processes. This is why platelet concentrates have been widely used in regenerative medicine, an emerging field that involves biomolecules, cells, and scaffold [...]

677 4438

Open Access Review

Scoping Review of Nutraceuticals Use in Mediterranean Diet

Received: 25 September 2023;  Published: 05 July 2024;  doi: 10.21926/obm.icm.2403039

Abstract

Mediterranean diet, considered key to varied diets, raises whether it is necessary to supplement it with compounds like nutraceuticals to obtain more benefits. A scoping review was conducted. Nine articles were selected that compared the effects of nutraceuticals on biochemical markers (such as total cholesterol (TC), low-density lipoprotein cholesterol (LDLc)), weight, and blood pressure in various studies to the results observed in groups only exposed to the Mediterranean diet. The aim was to assess the impact of [...]

802 4397

Open Access Editorial

Acknowledgment to Reviewers of OBM Integrative and Complementary Medicine in 2023

Received: 04 January 2024;  Published: 05 January 2024;  doi: 10.21926/obm.icm.2401005

Abstract

Food insecurity and insufficient access to affordable nutrition have been associated with increased risk for the development of multiple chronic medical conditions, including cardiovascular disease. In this narrative review, we explore the association between food insecurity and the development of chronic medical conditions that confer increased cardiometabolic risk, cardiovascular disease, and mortality. We also identify the various barriers leading to food insecurity and lack of food literacy, with an emphasis on [...]

891 4373

Open Access Short Report

X Ray-Induced Insulinoma Cell Line Rin-5F Has a Novel Mutation Site, C.A1459G (P.T487A), in Death Domain Associated Protein (DAXX) Gene

Received: 05 January 2024;  Published: 19 March 2024;  doi: 10.21926/obm.genet.2401223

Abstract

A popular toxicological and pharmacological research cell line is the insulin-secreting pancreatic cell line Rin-5F. The cell line originates from insulinomas induced by X-ray exposure. The author of this report looked at the mutation status of the DAXX gene in the Rin-5F cell line clone. The complete DNA and RNA were extracted from the cultivated cells as well. Double-stranded cDNA was then synthesized using the RNA template. Sequencing was done using a 3730xl DNA Analyzer. In the present study, c.A1459G (p.T487A) [...]

838 4368

Open Access Original Research

Hassles during the First Year of Medical School: Can a Student Wellness Program Make a Difference?

Received: 14 March 2024;  Published: 27 September 2024;  doi: 10.21926/obm.icm.2403057

Abstract

Acute stress during medical school affects medical student well-being. The objective of the current study was to examine the influence of a holistic, school-sponsored student wellness program (SWP) on acute stress during the first year of medical school. First-year medical students attending two osteopathic medical schools participated, one school with a holistic student wellness program (SWP group) and one without an organized student wellness program (Control group). The SWP was founded on osteopathic philosophy [...]

686 4353

Open Access Editorial

Acknowledgement to Reviewers of Advances in Environmental and Engineering Research in 2022

Received: 04 January 2023;  Published: 04 January 2023;  doi: 10.21926/aeer.2301002

Abstract

The editors of Advances in Environmental and Engineering Research would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can do [...]

867 4350

Open Access Review

An Exploration of the Psycho-Social Factors that Impact the Mental Wellbeing of Unaccompanied Asylum-Seeking Children in UK: A Narrative Review

Received: 23 January 2025;  Published: 17 July 2025;  doi: 10.21926/obm.icm.2503031

Abstract

Unaccompanied asylum-seeking children (UASC) are amongst the most vulnerable populations worldwide, facing significant psycho-social and mental health challenges influenced by pre-migration, migration, and post-migration experiences. This narrative review examines the structural, legal, and practical factors affecting UASC, focusing on their lived experiences within the UK’s asylum system. Key areas explored include trauma caused by forced migration (pre-, during and post-migration), ethical dilemmas surrounding ag [...]

574 4345

Open Access Short Review

Maximal 4-Second Cycle Accelerations Attenuate Sarcopenia and Improve Cardiovascular Function in Older Adults

Received: 20 February 2025;  Published: 08 August 2025;  doi: 10.21926/obm.geriatr.2503320

Abstract

The shrinkage of muscles with age, beginning at 30 y and accelerating in old age, is due largely to atrophy of fast-twitch muscle fibers (FT) partly from disuse. It was our purpose to develop an exercise program that is effective and time efficient at stimulating FT, as well as slow-twitch fibers (ST), to offset their atrophy. FT are recruited during movements requiring very high force and/or high velocity. We developed a safe exercise cycle that allows a person to ‘accelerate’ with the maximal effort needed to rec [...]

859 4309

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