The Cellular Mechanism of Aging as Programmed Epigenetic Phenomenon: From Hypothesis to Scientific Evidence
Abstract
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The Cellular Mechanism of Aging as Programmed Epigenetic Phenomenon: From Hypothesis to Scientific EvidenceAbstract
There is a main difference between theories explaining aging as an adaptive phenomenon that is determined and modulated by genes (i.e., the result of a specific “program”) and theories explaining aging as a non-adaptive phenomenon caused by the accumulation of random degenerative events. In fact, for adaptive theories, a genetically determined and modulated program determining aging is indispensable, while for non-adaptive theories, such a program cannot exist. However, there appears to be strong evidence to suppor [...] 685 3220 |
Photon Recycling for Indoor Energy Harvesting: Optical Optimization of LED-Driven Silicon Photovoltaic Systemsby
Abstract
Indoor environments offer a unique opportunity for photon recycling using LED-based illumination, particularly to address energy limitations of solar photovoltaic (PV) systems during nighttime or in low-light conditions. This study presents an optical and electrical performance evaluation of silicon-based photovoltaic (SPV) panels operating under controlled indoor LED lighting. Despite the low irradiance (~1.4 mW/cm2), significant power output was achieved through engineered panel configurations and optimized light [...] 542 3204 |
The Identification and Classification of Novel Genetic Variants in the MCPH1 Gene Suggest Association with Non-Syndromic Hearing ImpairmentAbstract
Human mouse orthologous hearing impairment genes were investigated in African patients for causal variants. A homozygous mutation in exon 13 of the microcephalin1 (MCPH1) gene, which encodes the BRCA1-carboxyl terminal 2 domain (BRCT2), was reported in non-syndromic hearing impairment (NSHI). The present study aims to investigate further the emerging roles of MCPH1 in the genetics of NSHI in African patients in the new and larger cohorts. This study screened multiplex families and isolated cases, including 90 patie [...] 536 3185 |
The Contribution of Dietary Fatty Acids to Prediction of All-Cause Mortality in a Cohort of Middle-Aged Men Followed-Up for 61 Years Until ExtinctionAbstract
To describe the contribution of three classes of dietary fatty acids to all-cause mortality and age at death among middle-aged men followed up for 61 years until extinction. The cohort comprised 1712 men aged 40-59 years at entry examination in 1960, belonging to the Italian Rural Areas of the Seven Countries Study of Cardiovascular Diseases. A dietary survey allowed to estimate dietary fatty acids [saturated (SAFA), mono-unsaturated (MUFA), poly-unsaturated (PUFA) and their ratios (M/S, P/S)] that were fed as poss [...] 615 3170 |
Anticipatory Care Plan for End-Stage Chronic Kidney Patients – Case ReportAbstract
Chronic Kidney Disease is characterized by progressive, persistent, and irreversible loss of kidney function, with a high prevalence and increasing trend in the population. An important observation, common to all recent studies, is the constant changes experienced by these individuals. Analytical changes, health status and the patient's preferences should be considered when planning anticipatory care at any phase of the disease. To comprehend the significance of the Anticipatory Care Plan for Patients with End-Stag [...] 583 3137 |
Exercise Training and Cardioprotection in Cardiovascular Disease: A Review of MechanismsAbstract
Cardiovascular disease remains the leading cause of death worldwide, prompting extensive research into effective methods for treatment and prevention. Among these, exercise training and physical activity are widely recognized as the safest and most effective strategies for improving health. Specifically, exercise training has been explored for its role in cardioprotection, particularly in reducing damage caused by ischemia-reperfusion (I/R) injury and myocardial infarction (MI). Both high-intensity interval trainin [...] 450 3120 |
Versatility of the Axillary Intra-Aortic Balloon Pump in Adult Cardiac SurgeryAbstract
The axillary intra-aortic balloon pump (ax-IABP) has been proposed as an alternative to the femoral IABP, particularly for patients with comorbidities rendering them unsuitable for fem-IABP insertion. Patient mobilisation with the ax-IABP in situ is deemed an additional potential benefit. We reviewed our experience with the ax-IABP. A single-centre retrospective review of all adult patients undergoing cardiac surgery (including heart transplantation) in a UK quaternary cardiac surgery centre between 2017 and 2021 w [...] 487 3118 |
Acknowledgment to Reviewers of Catalysis Research in 2024Abstract
The editors of Catalysis Research would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web [...] 512 3106 |
Art of Telesupport of Caregiver during Myasthenia Gravis Crisis by COVID-19 Infection-Related Followed by Rescue in Late-Onset PatientAbstract
An 83-year-old man with myasthenia gravis was hospitalized in the ICU; support for caregivers of elderly myasthenic patients in the ICU can be a crucial aspect of their care. Myasthenia gravis is a chronic autoimmune neuromuscular disease that can cause varying levels of muscle weakness, which can significantly impact the patient's day-to-day activities and overall quality of life. This intervention was followed for over one month with success. The critical phases are presented and analyzed as a medical support art [...] 622 3101 |
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