Table of Content

Open Access Original Research

Computer-Aided Study on Metal Complexes with Benzohydrazide Schiff Base as Potential Bacterial and Fungi Inhibitors

Received: 22 October 2024;  Published: 06 March 2025;  doi: 10.21926/rpse.2501002

Abstract

The biochemical properties of metal complexes containing benzo hydrazide Schiff base have been reported by numerous researchers worldwide in various ways. In this work, the evaluation of biochemical roles of the metal complexes with benzo hydrazide Schiff base activity as anti-gram positive and gram-negative bacteria, as well as antifungal agents, were observed. The use of various techniques, including the induced fit docking methodology, the density functional theory method, and pharmacokinetics investigations wit [...]

1299 5166

Open Access Original Research

Experiences and Support Needs of Informal Caregivers in Managing Behavioral Symptom of Dementia

Received: 03 October 2024;  Published: 10 April 2025;  doi: 10.21926/obm.geriatr.2502306

Abstract

About 90% of people living with Alzheimer's disease and related dementias experience behavioral and psychological symptoms during the course of the disorder. Although extensive research exists on the roles of informal caregivers in dementia care, their abilities to manage behavioral symptoms and the resources they turn to for support remain understudied. This phenomenological study explored informal caregivers' experience, knowledge sources, and self-initiated strategies for managing behavioral symptoms of dementia [...]

1025 5165

Open Access Short Review

Maximal 4-Second Cycle Accelerations Attenuate Sarcopenia and Improve Cardiovascular Function in Older Adults

Received: 20 February 2025;  Published: 08 August 2025;  doi: 10.21926/obm.geriatr.2503320

Abstract

The shrinkage of muscles with age, beginning at 30 y and accelerating in old age, is due largely to atrophy of fast-twitch muscle fibers (FT) partly from disuse. It was our purpose to develop an exercise program that is effective and time efficient at stimulating FT, as well as slow-twitch fibers (ST), to offset their atrophy. FT are recruited during movements requiring very high force and/or high velocity. We developed a safe exercise cycle that allows a person to ‘accelerate’ with the maximal effort needed to rec [...]

1063 5165

Open Access Research Article

Analysis of Global Scientific Production on Health Service Waste through Bibliometric and Scientometric Indicators

Received: 19 October 2024;  Published: 27 April 2025;  doi: 10.21926/aeer.2502021

Abstract

Inadequate management of healthcare waste represents a significant challenge to public health and the environment. This study aims to analyze global scientific production on healthcare waste using bibliometric and scientometric indicators, providing a comprehensive overview of research trends and areas of interest. Data from academic databases were used to map the temporal distribution of publications, identify the leading countries, institutions, and researchers involved, and evaluate collaboration networks and jo [...]

1244 5162

Open Access Review

Trends in Breast Cancer Epigenetics Research from 1993 to 2023: A Bibliometric Analysis

Received: 12 January 2025;  Published: 15 August 2025;  doi: 10.21926/obm.genet.2503307

Abstract

Breast cancer is a significant health problem. Epigenetic alterations that influence gene expression were implicated in breast cancer pathogenesis. Bibliometric analysis can be done to evaluate the existing literature and identify gaps and emerging trends. This bibliometric analysis aims to provide an overview of the current landscape of global breast cancer epigenetics research, identify existing networks of countries and authors’ keywords, and assess the association of a country’s socioeconomic indica [...]

860 5145

Open Access Review

Exploring Multitargets Treatment for Diabetes

Received: 17 February 2024;  Published: 30 July 2024;  doi: 10.21926/obm.genet.2403254

Abstract

Diabetes Mellitus (DM) is a degenerative disease that modifies the body’s glucose metabolism. Although glucose is a vital energy source for body cells, individuals with diabetes can either not use insulin efficiently or do not create enough of this hormone, which controls blood sugar. This review aimed to explore the multi-target treatment for diabetes. This study investigates explicitly recent reports published in peer-reviewed journals indexed in various databases, including Web of Science, Scopus, PubMed, Google [...]

769 5132

Open Access Original Research

Characterization of Patients with Functional Syndromes and Paradoxical Response to Hypnotic Relaxation

Received: 30 July 2024;  Published: 27 April 2025;  doi: 10.21926/obm.icm.2502019

Abstract

Hypnotherapy is effective for treating functional symptoms; however, some studies describe a paradoxical response to hypnotic relaxation. We hypothesized that functional patients who: 1) are aware of a stressful antecedent event and 2) recognize that stress is causing or exacerbating their symptoms would have reduced symptom-severity with hypnotic relaxation, whereas patients who do not perceive a stressful antecedent and do not recognize stress as causing symptoms, would more commonly experience paradoxical respon [...]

820 5114

Open Access Editorial

In the Mirror of the Past, in the Light of the Future: The ISLA – A President Looks Back and Forward

Received: 15 June 2025;  Published: 18 June 2025;  doi: 10.21926/obm.icm.2502024

Abstract

This editorial for the 27th ISLA Congress in Beverungen in Germany reflects on the development, achievements, and challenges of the International Society for Medical Laser Applications (ISLA-transcontinental) from the perspective of its President for Science and Research, Univ.-Prof. DDr. Gerhard Litscher. It reviews the organization’s milestones and growth while outlining future strategies for innovation, research, and international collaboration in medical laser technologies. The full keynote presentation is avai [...]

1439 5108

Open Access Review

Love in the Time of COVID: Psychiatric Outcomes Related to Oxytocin and the “Endocrine Organ”

Received: 09 February 2025;  Published: 09 May 2025;  doi: 10.21926/obm.neurobiol.2502287

Abstract

The COVID-19 pandemic was an eye-opener for many medical disciplines. It highlighted viral exploitation of physiological cellular processes, including endocytosis and cellular senescence. These pathways play an essential role in cancer, neurodegenerative disorders, and schizophrenia (SCZ). Oxytocin, commonly called the “love hormone,” is produced in the posterior hypothalamus and is crucial for various physiological processes, including social intelligence, sexual activity, and metabolism. Many viruses, [...]

936 5090

Open Access Interview

An Interview with Dr. David G. Smithard

Received: 09 October 2022;  Published: 09 October 2022;  doi: 10.21926/obm.geriatr.2204207

Abstract

Open AccessOBM GeriatricsInterviewAn Interview with Dr. David G. SmithardOBM Geriatrics Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: geriatrics@lidsen.comOBM Geriatrics 2022, volume 6, issue 4 doi:10.21926/obm.geriatr.2204207Received: October 09, 2022Accepted: October 09, 2022Published: October 09, 2022

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