by Alan M Iwahashi  , Samantha H Garvanovic  , Uoo R Kim  and Melissa D McCabe

Received: 29 August 2024;  Published: 20 March 2025;  doi: 10.21926/obm.transplant.2501243

Spontaneous coronary artery dissection (SCAD) accounts for one-third of all peripartum myocardial infarction. Peripartum SCAD is associated with increased severity. We surmise that altered maternal cardiac physiology increases susceptibility to SCAD and warrants consideration when managing cardiac ischemia. One week after vaginal delivery, a 35-year-old woman with no known medical history developed multivessel SCAD and cardiogenic shock after attempted percutaneous coronary intervention, requiring rescue CABG and p [...]

by Ellen Zhang  and Gerhard Litscher

Received: 11 September 2024;  Published: 11 September 2024;  doi: 10.21926/obm.icm.2403050

In this interview Professor Gerhard Litscher discusses how new technologies like laser acupuncture and electroacupuncture, artificial intelligence (AI), and robotics are revolutionizing acupuncture by enhancing precision and personalization. He emphasizes the potential for digital tools to improve treatment outcomes and training while maintaining the human aspect of this holistic practice. Litscher highlights the importance of interdisciplinary collaboration and ongoing education to successfully integrate these inn [...]

by Eli Cwinn  and Kayla Hamel

Received: 22 January 2024;  Published: 10 July 2024;  doi: 10.21926/obm.icm.2403041

This paper argues that psychology, as a discipline, requires research to be situated in the context of a content-based theory. We identify several problems and pitfalls with requiring a content-based theory for applied mental health research, a priori. Nonetheless, we also articulate a rationale for why theory matters and that a new sort of theoretical framework is required for applied mental health research. We address this need by articulating a new theoretical framework called Applied Pragmatic Functional Contex [...]

by Karen A. Roberto  , Pamela B. Teaster  and Imogen Fua

Received: 23 August 2024;  Published: 09 January 2025;  doi: 10.21926/obm.geriatr.2501294

The purpose of this descriptive study was to understand the nature, extent, and challenges confronted by APS programs in the United States in providing services to older clients affected by opioids. The study design involved a two-step process: Phase I involved telephone interviews with state-level Adult Protective Services administrators from 11 states considered to be “hot-bed states” for the opioid epidemic. Findings from the administrator interviews informed questions for Phase II telephone interviews with indi [...]

by Zohar Gabay  , Tal Eliav  , Oded Hammerman  , Odelia Elkana  , Maor Epstein  , Erez Yaakobi  and Yacov Ezra

Received: 30 July 2024;  Published: 27 April 2025;  doi: 10.21926/obm.icm.2502019

Hypnotherapy is effective for treating functional symptoms; however, some studies describe a paradoxical response to hypnotic relaxation. We hypothesized that functional patients who: 1) are aware of a stressful antecedent event and 2) recognize that stress is causing or exacerbating their symptoms would have reduced symptom-severity with hypnotic relaxation, whereas patients who do not perceive a stressful antecedent and do not recognize stress as causing symptoms, would more commonly experience paradoxical respon [...]

by Amarachi Nkwoada

Received: 28 November 2024;  Published: 02 December 2024;  doi: 10.21926/cr.2404013

by Abel Kolawole Oyebamiji  , Ifeoluwa Samson Ajayi  , Faith Eniola Olujinmi  , Godwin O. Olujinmi  , Sunday A. Akintelu  , Emmanuel T. Akintayo  , Cecilia O. Akintayo  and Oluwakemi Ebenezer

Received: 22 October 2024;  Published: 06 March 2025;  doi: 10.21926/rpse.2501002

The biochemical properties of metal complexes containing benzo hydrazide Schiff base have been reported by numerous researchers worldwide in various ways. In this work, the evaluation of biochemical roles of the metal complexes with benzo hydrazide Schiff base activity as anti-gram positive and gram-negative bacteria, as well as antifungal agents, were observed. The use of various techniques, including the induced fit docking methodology, the density functional theory method, and pharmacokinetics investigations wit [...]

by Urs Nydegger  and Paul Imbach

Received: 18 July 2024;  Published: 23 January 2025;  doi: 10.21926/obm.geriatr.2501297

In addition to their hemostatic functions, platelets play an essential role in immunologic interactions, which is confirmed by the observation of an increase in platelet counts in patients with immune-related thrombocytopenia and other autoimmune diseases after immunomodulatory treatment with intravenous human immunoglobulin concentrate. The mechanisms of action of this biological therapeutic option induce the development of therapeutic monoclonal antibodies, agonists, and antagonists that target the complex pathop [...]

by Mojtaba Ehsanifar  , Akram Gholami  and Joseph P Reiss

Received: 13 June 2025;  Published: 21 October 2025;  doi: 10.21926/obm.neurobiol.2504305

Evidence from recent studies has suggested a significant association between mycotoxin exposure and neuroinflammation, potentially contributing to the onset of neurocognitive disorders during key developmental stages of the brain. Various research highlights how exposure to these toxins is correlated with a decline in cognitive performance, reduced motor skills, and behavioral issues. Mycotoxins are also implicated in interfering with neuronal signaling pathways and the functioning of neurotransmitters, which may l [...]

by Phumzile Mkhize  and Phetole Mangena

Received: 16 July 2024;  Published: 16 October 2024;  doi: 10.21926/obm.genet.2404267

Breeding drought-tolerant genotypes using genetic and biochemical tools is an important mitigation strategy to improve stress response and yields in bottle gourd [Lagenaria siceraria (Molina) Standl.]. This current study evaluated the variations among bottle gourd genotypes for potential breeding purposes by establishing the relationship between agronomic traits and the protein profile required for the plants’ resilience against drought stress. The study assessed 12 bottle gourd accessions grown under non-str [...]