Table of Content

Open Access Editorial

Acknowledgment to Reviewers of OBM Integrative and Complementary Medicine in 2022

Received: 05 January 2023;  Published: 05 January 2023;  doi: 10.21926/obm.icm.2301003

Abstract

The editors of OBM Integrative and Complementary Medicine would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a cer [...]

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Open Access Case Report

Becker Phenotype Muscular Dystrophy in a Man with Klinefelter Syndrome: A Rare Association

Received: 08 July 2024;  Published: 26 September 2024;  doi: 10.21926/obm.genet.2403262

Abstract

To present a rare clinical case of a man affected simultaneously by Becker phenotype Muscular Dystrophy (MD) and Klinefelter syndrome and the way how he was diagnosed. A 35-year-old man was evaluated in the context of hospitalization for respiratory failure. Since childhood, he had a clinical and muscle biopsy diagnosis of muscular dystrophy, possibly type Becker. His physical examination showed severe weakness of the pelvic and shoulder girdle, with a waddling gait, grade II scoliosis associated with tall height, [...]

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Open Access Case Report

Feasibility and Physiological Effects of a Home-Based Swallow Exercise Program Using sEMG Biofeedback in Prefrail Older Adults: A Case Series

Received: 28 April 2025;  Published: 13 August 2025;  doi: 10.21926/obm.geriatr.2503322

Abstract

Age-related decline in swallowing function increases the risk of dysphagia in older adults. Strengthening the muscles involved in swallowing through proactive training may help prevent such decline, particularly in prefrail individuals. This case series evaluated the feasibility and physiological effects of a home-based effortful swallow training program in three prefrail older adults without swallowing impairments. The intervention used a wearable surface electromyography biofeedback device (Mobili-T®) to provide [...]

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Open Access Original Research

Opioid-Involved Elder Abuse in the United States: Perspectives from Adult Protective Services

Received: 23 August 2024;  Published: 09 January 2025;  doi: 10.21926/obm.geriatr.2501294

Abstract

The purpose of this descriptive study was to understand the nature, extent, and challenges confronted by APS programs in the United States in providing services to older clients affected by opioids. The study design involved a two-step process: Phase I involved telephone interviews with state-level Adult Protective Services administrators from 11 states considered to be “hot-bed states” for the opioid epidemic. Findings from the administrator interviews informed questions for Phase II telephone interviews with indi [...]

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Open Access Review

Engaging with an Industrial Pandemic: Drivers of and Responses to the Expansion of Ultra-Processed Foods in East and Southern Africa

Received: 14 January 2025;  Published: 29 August 2025;  doi: 10.21926/rpn.2503018

Abstract

Intensified marketing and expanding consumption of ultra-processed foods (UPFs) that contain high sugar, salt, trans-fats and other additives and sugar sweetened beverages in Sub-Saharan Africa (SSA) are associated with rising obesogenic environments and non-communicable diseases, termed by some an ‘industrial pandemic’ due to its commercial drivers and cross border nature. This review paper addresses the question of how far SSA, positioned at an early point of a rising wave, is controlling this growing health chal [...]

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Open Access Review

Platelet Immune Interactions, Lifespan, and Senescence

Received: 18 July 2024;  Published: 23 January 2025;  doi: 10.21926/obm.geriatr.2501297

Abstract

In addition to their hemostatic functions, platelets play an essential role in immunologic interactions, which is confirmed by the observation of an increase in platelet counts in patients with immune-related thrombocytopenia and other autoimmune diseases after immunomodulatory treatment with intravenous human immunoglobulin concentrate. The mechanisms of action of this biological therapeutic option induce the development of therapeutic monoclonal antibodies, agonists, and antagonists that target the complex pathop [...]

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Open Access Original Research

Computer-Aided Study on Metal Complexes with Benzohydrazide Schiff Base as Potential Bacterial and Fungi Inhibitors

Received: 22 October 2024;  Published: 06 March 2025;  doi: 10.21926/rpse.2501002

Abstract

The biochemical properties of metal complexes containing benzo hydrazide Schiff base have been reported by numerous researchers worldwide in various ways. In this work, the evaluation of biochemical roles of the metal complexes with benzo hydrazide Schiff base activity as anti-gram positive and gram-negative bacteria, as well as antifungal agents, were observed. The use of various techniques, including the induced fit docking methodology, the density functional theory method, and pharmacokinetics investigations wit [...]

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Open Access Editorial

Opportunities and Challenges of Molecular Catalysts

Received: 28 November 2024;  Published: 02 December 2024;  doi: 10.21926/cr.2404013

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Open Access Original Research

Characterization of Patients with Functional Syndromes and Paradoxical Response to Hypnotic Relaxation

Received: 30 July 2024;  Published: 27 April 2025;  doi: 10.21926/obm.icm.2502019

Abstract

Hypnotherapy is effective for treating functional symptoms; however, some studies describe a paradoxical response to hypnotic relaxation. We hypothesized that functional patients who: 1) are aware of a stressful antecedent event and 2) recognize that stress is causing or exacerbating their symptoms would have reduced symptom-severity with hypnotic relaxation, whereas patients who do not perceive a stressful antecedent and do not recognize stress as causing symptoms, would more commonly experience paradoxical respon [...]

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Open Access Original Research

Duration of Hospitalization is Associated with the Gut Microbiome in Patients Undergoing Hematopoietic Stem Cell Transplantation: Early Results from a Randomized Trial of Home Versus Hospital Transplantation

Received: 24 April 2025;  Published: 25 August 2025;  doi: 10.21926/obm.transplant.2503255

Abstract

Home-based hematopoietic stem cell transplantation (HCT) is an innovative care model with growing interest, but its impact on the gut microbiome remains unexplored in a randomized setting. We present interim results from the first randomized controlled trials (RCT) evaluating the effect of HCT location—home versus hospital—on gut microbial diversity and antimicrobial resistance (AMR) gene carriage. We hypothesize that patients randomized to undergo home HCT would have higher gut taxonomic diversity and lower AMR ge [...]

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