by Urs Nydegger  and Paul Imbach

Received: 18 July 2024;  Published: 23 January 2025;  doi: 10.21926/obm.geriatr.2501297

In addition to their hemostatic functions, platelets play an essential role in immunologic interactions, which is confirmed by the observation of an increase in platelet counts in patients with immune-related thrombocytopenia and other autoimmune diseases after immunomodulatory treatment with intravenous human immunoglobulin concentrate. The mechanisms of action of this biological therapeutic option induce the development of therapeutic monoclonal antibodies, agonists, and antagonists that target the complex pathop [...]

by Junfeng Zhang  , Yajie Li  , Qianghua Xue  , Wen He  , Chenchen Li  and Yanli Wang

Received: 21 January 2025;  Published: 12 May 2025;  doi: 10.21926/obm.icm.2502021

Evidence suggests that regular moderate exercise can improve symptoms of depression and may enhance immune function, with an interesting role in cancer prevention and improved cancer-related prognosis; however, over-exercising may lead to overtraining and generate psychological symptoms that mimic depression, and may impair immune function. In this study, we chose swimming as an exercise form to conduct research. Swimming groups were divided into 5, 20, and 60 min day-1, and open field tests (OFT) were used to asse [...]

by Adonis Sfera  , Sabine Hazan  , Jacob Anton  , Ioana Ciuperca  , Carolina Klein  and Karina G. Thomas

Received: 09 February 2025;  Published: 09 May 2025;  doi: 10.21926/obm.neurobiol.2502287

The COVID-19 pandemic was an eye-opener for many medical disciplines. It highlighted viral exploitation of physiological cellular processes, including endocytosis and cellular senescence. These pathways play an essential role in cancer, neurodegenerative disorders, and schizophrenia (SCZ). Oxytocin, commonly called the “love hormone,” is produced in the posterior hypothalamus and is crucial for various physiological processes, including social intelligence, sexual activity, and metabolism. Many viruses, [...]

by Buratovich María Victoria  and Acciaresi Horacio Abel

Received: 04 July 2024;  Published: 06 January 2025;  doi: 10.21926/aeer.2501004

The aim of this work was to determine the photosynthetically active radiation interception (iPAR) during the cover crop (CC) growth cycle, the number and aerial dry matter (ADM) of weeds, and productivity in the following soybean and maize rotation crop. To do this, experiments with CC were performed in 2015-2016 using Hordeum vulgare L., Lolium multiflorum L., Avena sativa L., Bromus unioloides L., Vicia villosa L., Brassica campestris L., Raphanus sativus L., and Avena sativa/Vicia villosa. The iPAR at the vegeta [...]

by Natsumi Sakata  , Yuka Horio  , Keiko Wakimoto  , Ryoichi Yamaji  , Hidenobu Sumitani  and Yuji Isegawa

Received: 31 August 2024;  Published: 01 April 2025;  doi: 10.21926/rpn.2502005

We have previously demonstrated the anti-influenza virus activity of a soybean extract, indicating the presence of compounds that prevent viral entry into cells. In this study, we sought to identify the compounds in hydrothermal extracts of soybean that blocked viral entrance and analyzed their mechanisms of action. Hot aqueous extracts of roasted soybeans were separated by reverse-phase chromatography on an octadecylsilyl C18 column, and the antiviral activity of individual fractions was measured during the viral [...]

by Fatemeh Mollaamin

Received: 11 November 2024;  Published: 06 March 2025;  doi: 10.21926/cr.2501003

Being critical to achieving Sustainable Development Goals (SDGs) of the United Nations, strengthening understanding of the properties and processes of soil at national and regional scales is imperative. The target of this research is removing transition metals of Cr, Mn, Fe, Zn, W, Cd from soil due to nanomaterial-based boron nitride nanocage (B5N10-nc). The electromagnetic and thermodynamic attributes of toxic transition metals trapped in B5N10-nc were depicted by materials modeling. It has been studied the behavi [...]

by Sarah L. Wells  and Raymond H. Baillargeon

Received: 31 May 2024;  Published: 08 February 2025;  doi: 10.21926/obm.icm.2501009

Disruptive behavior problems (DBPs) in young children are early indicators of potential disruptive behavior disorders (DBD), which can lead to negative health and social outcomes. Secondary prevention strategies that target DBPs may facilitate early interventions and reduce these risks. Current Canadian pediatric practice guidelines provide an example one such strategy and suggest screening for DBPs only if a child’s parent reports concerns about their behavior. This systematic review sought to determine if parents [...]

by Valeri Ligatchev

Received: 28 December 2024;  Published: 22 May 2025;  doi: 10.21926/rpm.2502008

So-called ‘Generalized Skettrup Model(s)’ (GSMs) of different (1D, 2D, 3D) spatial dimensionalities are used at simulations on temperature-dependent harmonic and anharmonic fractions of lattice thermal capacity of polyethylene and polypropylene with crystalline and/or amorphous atomic structures of limited spatial extents. Basic equations of the GSM slot in explicitly quantization effects of the single-particle and many-particle energy levels of spatially confined phonons. The harmonic lattice thermal c [...]

by Alan M Iwahashi  , Samantha H Garvanovic  , Uoo R Kim  and Melissa D McCabe

Received: 29 August 2024;  Published: 20 March 2025;  doi: 10.21926/obm.transplant.2501243

Spontaneous coronary artery dissection (SCAD) accounts for one-third of all peripartum myocardial infarction. Peripartum SCAD is associated with increased severity. We surmise that altered maternal cardiac physiology increases susceptibility to SCAD and warrants consideration when managing cardiac ischemia. One week after vaginal delivery, a 35-year-old woman with no known medical history developed multivessel SCAD and cardiogenic shock after attempted percutaneous coronary intervention, requiring rescue CABG and p [...]

by Tracie D. Parkinson  and Stephen D. Smith

Received: 11 March 2025;  Published: 23 September 2025;  doi: 10.21926/obm.icm.2503039

Hatha yoga is a common style of yoga used for physical, emotional, mental, and spiritual benefits, enhancing quality of life and well-being. The current study used a randomized control trial (RCT) to investigate whether completing an eight-week posture-based Hatha yoga program would lead to greater psychological benefits than taking part in an eight-week lecture series about the history and philosophy of yoga. Fifty-five participants (42 female, age range 18-32) completed five self-report measures both before and a [...]