by Bolanle Adenike Akinsanola  , Matthew Iyobhebhe  , Tobiloba Christianah Maduakolam-Aniobi  , Tomilola Debby Olaolu  , Damilare Emmanuel Rotimi  and Oluwafemi Adeleke Ojo

Received: 17 February 2024;  Published: 30 July 2024;  doi: 10.21926/obm.genet.2403254

Diabetes Mellitus (DM) is a degenerative disease that modifies the body’s glucose metabolism. Although glucose is a vital energy source for body cells, individuals with diabetes can either not use insulin efficiently or do not create enough of this hormone, which controls blood sugar. This review aimed to explore the multi-target treatment for diabetes. This study investigates explicitly recent reports published in peer-reviewed journals indexed in various databases, including Web of Science, Scopus, PubMed, Google [...]

by Anita Padmanabhanunni  and Tyrone Pretorius

Received: 21 September 2024;  Published: 27 January 2025;  doi: 10.21926/obm.neurobiol.2501266

Generalized Anxiety Disorder (GAD) is a prevalent mental health condition and the GAD-7 is widely used as a screening tool and measure of GAD severity. However, research has yielded conflicting findings regarding the factor structure of the instrument, with some studies supporting a unidimensional interpretation while others suggest a two-factor solution. These inconsistencies highlight the importance of validating the GAD-7 across diverse populations. This study aimed to assess the psychometric properties and fact [...]

by Oluwafemi G. Oluwole

Received: 25 April 2024;  Published: 06 December 2024;  doi: 10.21926/obm.genet.2404273

Precision medicine describes the definition of disease at a higher resolution by genomic and other technologies to enable more precise targeting of disease subgroups with new therapies. Preventative or therapeutic interventions can be developed with the knowledge of how a compound acts safely in the body to target receptors and produce the desirable effect. With the completion of the Human Genome Project in 2003 and the rapid increase in sequencing and bioinformatics tools, obtaining information about a person's ge [...]

by Fatemeh Mollaamin

Received: 15 August 2024;  Published: 07 November 2024;  doi: 10.21926/jept.2404019

A comprehensive investigation on hydrogen grabbing by SiO-GeO was carried out, including DFT computations at the CAM-B3LYP-D3/6-311+G (d,p) level of theory. The data shows that if silicon elements are replaced by germanium, the H-grabbing energy will be ameliorated. Electromagnetic and thermodynamic properties of SiO, GeO, and SiO-GeO nanoclusters have been evaluated. The hypothesis of the hydrogen adsorption phenomenon was confirmed by density distributions of PDOS and LOL for hydrated nanoclusters of H-SiO, H-GeO [...]

by Regina M. Mackey  , Macaila Eick  , Sara Jacobsen  , Abraham Labrada Satiago  and Maria I. Lapid

Received: 26 February 2024;  Published: 01 July 2024;  doi: 10.21926/obm.geriatr.2403281

How should Palliative Medicine competencies be taught to medical students? In the United States and other countries, there is a consensus that teaching Palliative Medicine competencies to medical students is essential. Health agencies have also identified teaching Palliative Medicine competencies as crucial. According to Sanchez-Reilly and Ross, medical students reported that they feel better prepared to care for the elderly, patients with severe illness, and dying patients after completing formal training. The aut [...]

by Koji Kawago  , John A Farag  , Yujiro Kawai  , Umayr Syed  , Eric Pfrender  , Satoshi Miyairi  and Yasuhiro Shudo

Received: 21 October 2024;  Published: 14 March 2025;  doi: 10.21926/obm.transplant.2501242

Heterotopic heart transplantation (HHT) in rats is a valuable tool for cardiac transplantation research. While abdominal HHT has been established in rats for nearly 90 years, novel approaches involving cervical and femoral techniques have also been explored. The abdominal HHT model, despite its long history, is technically demanding and has a steep learning curve. In contrast, the cervical HHT model enables surgeons with more basic microsurgical skills to achieve competency more quickly while producing comparable o [...]

by Pamela Whitaker

Received: 07 June 2024;  Published: 25 September 2024;  doi: 10.21926/obm.icm.2403056

This concept paper is proposing the inclusion of the home studio as an art making location for art therapy trainees who assemble personal belongings, within the context of their domestic lives. A collection of belongings can become an installation which brings together associations to identities in juxtaposition. The material culture of art therapy trainees, the objects which they live by, is a new contribution to art therapy pedagogy, as it designates the art of personal collections as a life archive (or accumulat [...]

by Walter Calderón Gerstein  , Gabriela Torres Samaniego  and Kevin Pazos Sovero

Received: 30 November 2022;  Published: 12 April 2024;  doi: 10.21926/obm.genet.2402226

There is a lack of knowledge regarding the type of lung compromise in high-altitude residents with COVID-19. This study aims to evaluate the lung compromise in chest CT scans of high-altitude dwellers hospitalized with COVID-19. Retrospective study that took place in "Daniel Alcides Carrión" Regional Hospital, located 3,250 meters above sea level in the city of Huancayo, Perú. 464 medical charts and chest CT images of hospitalized patients with confirmed COVID-19 from January to March 2021 were reviewed. The mean a [...]

by Ahmad R. Alsayed  and Yazan Alsayed

Received: 26 August 2024;  Published: 25 February 2025;  doi: 10.21926/obm.transplant.2501237

This study was designed to investigate the ability of telemonitoring involving a secure electronic database called “Alsayed System for Applied Medical-Care Improvement” (ASAMI) to detect at least 95% of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). This prospective observational study, which took place over 16 months in 2022-2023, was based at a medical center in Jordan. The study group participants were patients with COPD (from seven countries) with mixed levels of airflow limitation sever [...]

by OBM Geriatrics Editorial Office

Received: 25 June 2023;  Published: 27 June 2023;  doi: 10.21926/obm.geriatr.2302241

InterviewAn Interview with Dr. Ines TestoniOBM Geriatrics Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: geriatrics@lidsen.comOBM Geriatrics 2023, volume 7, issue 2 doi:10.21926/obm.geriatr.2302241Received: June 25, 2023Accepted: June 26, 2023Published: June 27, 2023