by Marcel Tomaszewski  and Philip Wong

Received: 22 August 2018;  Published: 03 January 2019;  doi: 10.21926/obm.hg.1901013

There is evidence to suggest that older livers regenerate less well and display cellular senescence. Additionally, elderly patients with certain liver diseases have a less favourable course. Chronic liver disease, amongst the elderly, has a significant negative effect upon quality of life and functional independence. Frailty, commonly encountered in geriatric patients, remains a significant negative predictor of physical, psychological, functional and survival outcomes in chronic liver disease. Despite advances in [...]

by Joseph S. D'Arrigo

Received: 26 June 2022;  Published: 19 December 2022;  doi: 10.21926/obm.icm.2204054

The cardiovascular risk factors for dementia trigger widespread inflammation and oxidative stress. These two interacting processes lead to neurodegeneration, gradual cognitive/memory decline, and eventually (late-onset) dementia. In addition, there is supporting evidence pointing to elevated pulse pressure as a clear risk factor for cognitive decline. Accordingly, an effective therapeutic strategy to delay dementia could be based upon nanotargeting bioactive molecules, using lipid nanocarriers, toward cell-surface [...]

by Vladimir N. Gorchakov  , Kirill M. Nicolaychuk  , Olga V. Gorchakova  , Georgi A. Demchenko  and Bayan A. Nurmakhanova

Received: 09 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.geriatr.2304257

Lymph nodes are prioritized in protecting and ensuring endoecological safety at different periods of life, especially in retirement age. It destabilizes the structure and function of the lymphatic system and organs when aging increases the risk of comorbid conditions. This is a sign of age-related pathology. Improving lymph node function is an essential task in integrating gerontology and lymphology. The solution to this problem is possible with the help of a phytotherapeutic agent, which involves the evaluation of [...]

by OBM Hepatology and Gastroenterology

Received: 04 January 2021;  Published: 05 January 2021;  doi: 10.21926/obm.hg.2101054

The editors of OBM Hepatology and Gastroenterology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificat [...]

by Suat Morkuzu  , Alice Morello  , Giorgio Raposio  and Edoardo Raposio

Received: 18 July 2024;  Published: 27 November 2024;  doi: 10.21926/obm.neurobiol.2404258

Recent studies have identified that certain types of migraines, including frontal migraines, may be attributed to the irritation of specific extracranial nerves. This systematic review addresses the following questions: Which surgical techniques are most effective for chronic frontal migraines? How do combined surgical approaches compare to isolated procedures regarding efficacy and complication rates? Our objective is to comprehensively analyze surgical options for frontal migraines, including their success rates [...]

by Isadora Muller de Oliveira  , Letícia Caroline de Oliveira Vital  , Izabela de Siqueira Reis Regueira  and Marcos Paulo Gomes Mol

Received: 02 July 2025;  Published: 11 November 2025;  doi: 10.21926/aeer.2504031

The management of healthcare waste (HCW) presents a significant environmental and public health challenge, aggravated by gaps in current Brazilian federal regulations. This study provides a comprehensive analysis of specific state and municipal legislation on HCW, comparing it with ANVISA Resolution No. 222/2018 and CONAMA Resolution No. 358/2005 to ascertain whether local regulations enhance management practices and can act as supplementary instruments to federal guidelines. The methodology was structured into thr [...]

by Gabriel de Souza Vieira Bié  , Zilda de Castro Silveira  , Rafael Vidal Aroca  and Marcia Cristina Branciforti

Received: 07 February 2025;  Published: 28 May 2025;  doi: 10.21926/rpm.2502010

Tissue engineering is a technique for regenerating living tissue using portions of the patient's tissue, which are dissociated into cells and cultured on biological or synthetic supports before being transferred to the patient. In this context, the present study seeks to develop implant models (scaffolds) for replacing trabecular bone tissue, with requirements such as porosity and interconnected pores. All design development was aimed at the manufacturing of scaffolds using the material extrusion additive manufactu [...]

by Hannah O'Connor  , Joseph Biederman  , Maura DiSalvo  , Gagan Joshi  , Stephen V. Faraone  and Janet Wozniak

Received: 25 January 2024;  Published: 04 June 2024;  doi: 10.21926/obm.icm.2402031

The aim of this paper is to examine effects of stimulant treatment in children and adolescents with high levels of emotional dysregulation in a psychiatric outpatient clinic. Subjects were referred children and adolescents 6-17 years of age who presented to a child psychiatric outpatient clinic between September 2016-November 2021 and received a prescription for a stimulant medication. Children were stratified into those with low and high levels of emotional dysregulation as defined by an aggregate T-score of <1 [...]

by Candice Fischer  and Carolina Eugenia Cáceres Videla

Received: 21 March 2024;  Published: 12 August 2024;  doi: 10.21926/obm.icm.2403046

A growing body of evidence has highlighted the limitations of relying solely on positivist research when summarizing SP/SR results since it might hinder pluralistic perspectives from unique backgrounds and life experiences. In the present reflective report, I aim to conduct quantitative and qualitative research on myself to explore the impact of concentrating on genuineness when delivering psychotherapy as a trainee. This article provides concrete examples of how therapists’ authenticity could benefit the therapeut [...]

by Anna Scheyett  , Virginia Brown  and Christopher Weatherly

Received: 24 September 2024;  Published: 16 January 2025;  doi: 10.21926/obm.icm.2501005

In this conceptual paper we apply the construct of time poverty to a novel population, farmers struggling with stress and mental health challenges. Farmers have rates of suicide that can be over three times that of the general population, with depression and anxiety at double general population rates. These are linked to the multiple stressors farmers experience due to the unpredictable nature of their work, such as weather, input costs, commodity prices, and government regulations. In addition, there are multiple [...]