by Somaye-Sadat Heidari  , Nooshin Dalili  , Shiva Samavat  , Shiva Kalantari  , Leonard Foster  , Kyung-Mee Moon  and Mohsen Nafar

Received: 12 July 2023;  Published: 25 September 2023;  doi: 10.21926/obm.transplant.2303196

Acute antibody-mediated rejection (AMR) is a severe complication affecting kidney allografts' long-term survival. Timely detection and appropriate treatment of AMR are crucial for improving graft outcomes. This study aimed to discover non-invasive urinary biomarkers that can predict the response to therapy in patients with AMR. Materials and Methods: In this case-control study, urine samples from 21 biopsy-proven AMR patients underwent proteomics using label-free quantification. The patients were divided into two g [...]

by Alfonso H. Santos  , Amer Belal  , Hisham Ibrahim  and Muhannad A. Leghrouz

Received: 19 August 2022;  Published: 21 February 2023;  doi: 10.21926/obm.transplant.2301175

We aimed to identify the non-renal risk factors for simultaneous liver-kidney transplantation (SLKT) vs. liver transplantation alone (LTA) in end-stage liver disease (ESLD) patients with estimated glomerular filtration rate (eGFR) <60 ml/min, not on dialysis. Using organ procurement and transplantation network data, we studied adult ESLD patients who received deceased-donor SLKT or LTA in July 2002-Mar 2016 with a 4-point modification of renal disease (MDRD) equation-estimated glomerular filtration rate (eGFR) s [...]

by HIrotaka Yamamoto  , Maiko Kisino  , Shunichi Nakamura  and Kastutoshi Tokushige

Received: 12 November 2018;  Published: 27 December 2018;  doi: 10.21926/obm.hg.1804012

Objective: Elastography is a non-invasive examination method that can estimate the extent of liver fibrosis, measured as liver stiffness (LS). We examined the relationship between gastro-esophageal varices and the LS and how to predict esophageal varices and varices bleeding by LS. Methods: From 2014 to 2016, we conducted a retrospective study of 138 subjects, all of whom were patients with chronic liver disease, including NAFLD, alcoholic liver disease, primary biliary cholangitis, viral hepatitis, and others. LS [...]

by Richard J. Bloomer  , Alice Raphael Karikachery  , Velaphi C. Thipe  , Kavita K. Katti  , Kattesh V. Katti  , Mysore R. Harsha  , Vadakkanchery V. Vaidyanathan  , Caleb M. Schmidt  , Michael A. Schmidt  , Niraj A. Arora  , Bradley J. Ferguson  and Alton Michael Chesne

Received: 31 January 2025;  Published: 25 July 2025;  doi: 10.21926/rpn.2503014

Efficient glucose uptake by peripheral tissue is important for individuals who desire to maintain optimal wellbeing. Various methods to regulate postprandial blood glucose have been reported in the research literature, however, few have examined the effect of ketone esters on blood glucose levels. The present study evaluated blood glucose following the administration of an oral glucose tolerance test, with and without ketone esters delivered at two different dosages, in a sample of healthy Sprague-Dawley rats. We h [...]

by Ivan Stoyanov  , Penka Vasileva  , Teodora Staykova  , Teodora Popova  and Evgeniya N. Ivanova

Received: 22 June 2023;  Published: 14 December 2023;  doi: 10.21926/obm.genet.2304208

Data from the present study indicate that the neonicotinoid insecticides Nuprid 200 SL (with the active substance imidacloprid) and Calypso 480 SC (with the active substance thiacloprid) reduce the mitotic activity by inhibiting cell division and increasing chromosomal aberrations in the cells of the root apical meristem of Allium cepa L. The tested solutions of pesticides cause a wide range of anomalies associated with disorders in forming the cell's division apparatus and the integrity of chromosomes. The compara [...]

by Arbnora Batalli-Kepuska  , Lidvana Spahiu  , Emir Behluli  and Gazmend Temaj

Received: 08 February 2024;  Published: 19 July 2024;  doi: 10.21926/obm.genet.2403253

Several therapeutic methods are used to cure acute lymphoblastic leukemia (ALL). Relapsed/refractory B-cell ALL (R/R B-ALL) remains the primary cause of death worldwide due to the limitation of cure. Blinatumomab is a bispecific T-cell engaging antibody used to treat R/R B-ALL. The use of blinatumomab for treating R/R B-ALL has shown to be very efficient, especially as a bridge tool to hematopoietic stem cell transplantation (HSCT). The response to blinatumomab treatment ranged from 69% after two cycles in phase II [...]

by Michal Kawka  , Tamara MH Gall  and Long R Jiao

Received: 25 February 2019;  Published: 05 June 2019;  doi: 10.21926/obm.hg.1902022

Background: Severe necrotising pancreatitis (SNP) is characterised by high mortality, severe complications and bad prognosis despite progress in understanding of aetiology and progression of the disease. Traditionally, necrotic changes were removed by open necrosectomy but the paradigm has shifted towards more conservative management and minimally-invasive surgical procedures. However, there is still no consensus on the best management pathway. Minimally-invasive procedures percutaneous drainage, endoscopic transl [...]

by Luana Góes Soares  , Sandra Kunst  , Cláudia Trindade Oliveira  and Annelise Kopp Alves

Received: 04 February 2024;  Published: 01 July 2024;  doi: 10.21926/cr.2403007

Sustainability has driven the use of heterogeneous photocatalysis as one of the primary methods for environmental decontamination, reduction, degradation, remediation, or transformation of polluting chemical residues and purification treatment of effluents and wastewater. TiO2 is the most commonly used semiconductor in heterogeneous photocatalysis. It acquires relevance, as it has favorable properties, such as non-toxicity, stability in a wide range of pH, economic viability, etc., which encourage its application a [...]

by Dafni Foti  , Costas Passialis  , Elias Voulgaridis  and Stergios Adamopoulos

Received: 23 August 2022;  Published: 28 October 2022;  doi: 10.21926/rpm.2204022

Cellulosic fibrous mats were impregnated with various water-repellent formulations based on reclaimed polystyrene (5, 10, 15, and 20%), alkyd resin (5%), gum rosin (5%), and paraffin wax (0.5%). The mats were tested for their bursting strength and resistance to bending. They were also subjected to the ring crush test and short-span compression test. By increasing the concentration of total solid ingredients (5, 10, 15, 20, and 25.5%), the retention and grammage of the mats were increased, and all strength propertie [...]

by Joana Neto  and Félix Neto

Received: 08 February 2024;  Published: 12 April 2024;  doi: 10.21926/obm.neurobiol.2402217

Compassionate love (CL) is a recent subject of close relationships. CL is focused on enlarging beneficence to another. The present study approaches the test of the psychometric characteristics of the shortened form of the Compassionate Love Scale for a partner (CLS-P-SF) for Brazilian college students and its relationships with background and well-being variables. The sample included 217 young adults, 46.1% women and 53.9% men. Confirmatory factor analysis revealed that the single latent factor of the CLS-P-SF is g [...]