by Babak Sokouti

Received: 30 October 2024;  Published: 14 March 2025;  doi: 10.21926/obm.neurobiol.2501276

Delirium is an acute neurocognitive disorder marked by disruptions in attention, cognition, and awareness, particularly prevalent among older and critically ill patients. This study applies a systems biology framework to dissect the molecular underpinnings of delirium and evaluate natural compounds for potential therapeutic roles. Through bioinformatics analyses, key biomarkers related to delirium, including IL6, AKT1, JUN, APP, and PPARGC1A, were identified, implicating pathways tied to neuroinflammation, oxidativ [...]

by Sarah I. Willi  , Ulrike Bacher  , Marie Noelle Kronig  , Michael Daskalakis  , Lia Bally  and Thomas Pabst

Received: 29 July 2023;  Published: 04 February 2024;  doi: 10.21926/obm.transplant.2401206

Malnutrition remains a clinical challenge in AML patients undergoing autologous hematopoietic stem cell transplantation (ASCT), leading to physical deconditioning and prolonged hospitalization. Prospective data are mainly lacking to identify those patients who may particularly benefit from parenteral nutrition in this setting. This observational, non-randomized, retrospective, exploratory cohort study assessed the nutritional development in patients following high-dose chemotherapy (HDCT) with ASCT and explored the [...]

by Chandra Sekhar Devulapalli

Received: 07 July 2021;  Published: 22 July 2021;  doi: 10.21926/obm.hg.2103059

Non-celiac gluten sensitivity (NCGS) is a debatable condition that affects less than 6% of children. The absence of specific diagnostic markers and standardized diagnostic procedures make the diagnosis of NCGS challenging, covering patients with different and varied symptoms. Generally, the parents of small and younger children introduce a gluten-free diet (GFD) based on their personal experiences and expectations. Additionally, a “fad component” exists, contributing to the recent rise in the popularity of GFD. Thu [...]

by Vladimir N. Gorchakov  , Kirill M. Nicolaychuk  , Olga V. Gorchakova  , Georgi A. Demchenko  and Bayan A. Nurmakhanova

Received: 09 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.geriatr.2304257

Lymph nodes are prioritized in protecting and ensuring endoecological safety at different periods of life, especially in retirement age. It destabilizes the structure and function of the lymphatic system and organs when aging increases the risk of comorbid conditions. This is a sign of age-related pathology. Improving lymph node function is an essential task in integrating gerontology and lymphology. The solution to this problem is possible with the help of a phytotherapeutic agent, which involves the evaluation of [...]

by Recent Progress in Materials Editorial Office

Received: 29 August 2022;  Published: 30 August 2022;  doi: 10.21926/rpm.2203016

Interview An Interview with Prof. José Ignacio Álvarez GalindoRecent Progress in Materials Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: rpm@lidsen.comRecent Progress in Materials2022, volume 4, issue 3doi:10.21926/rpm.2203016Received: August 29, 2022Accepted: August 29, 2022Published: August 30, 2022

by Elena V. Kudryavtseva  , Sergey N. Fedenev  , Ilia V. Kanivets  , Anastasiya N. Troitskaya  and Vladislav V. Kovalev

Received: 30 April 2024;  Published: 05 August 2024;  doi: 10.21926/obm.genet.2403255

Assisted reproductive technologies (ART), including in vitro fertilization (IVF), are modern medical technologies widely used in developed countries. A frequent complication of pregnancy resulting from ART is miscarriage. The leading cause of miscarriage, both sporadic and recurrent, is chromosomal abnormalities (CA) of the embryo. To compare the frequency and structure of chromosomal abnormalities (CA) of the embryo during miscarriages after IVF and natural conception. Retrospective cohort comparative study. The s [...]

by Shih Ang Hsu

Received: 31 August 2023;  Published: 20 December 2023;  doi: 10.21926/aeer.2304054

In the realm of air-sea interaction and marine meteorology, during a tropical cyclone (TC) worldwide since 2006, the Regional and Mesoscale Meteorological Branch (RAMMB) has issued surface wind analysis. Based on this TC’s isotach (line of equal wind speed) analysis, in this paper, much more meteorological-oceanographic (met-ocean) products are developed and value-added to these isotachs. They are, for marine meteorology, overwater friction velocity, wind stress, atmospheric vorticity and the mean vertical velocity [...]

by Chaimae Merimi  , Abdessamad Benabbou  , Lamiae Bourassi  , Abdelhay Addous  , Ahmed A. Elhenawy  , Rachid Touzani  and Belkheir Hammouti

Received: 22 January 2025;  Published: 25 June 2025;  doi: 10.21926/obm.icm.2502027

Cardiovascular diseases and hypertension represent significant global health challenges, driving the need for innovative therapeutic solutions. In this study, we employed advanced in silico methods to investigate the molecular properties of two bioactive compounds, Flavonoids and Rosmarinic Acid, extracted from five medicinal plants: Rosemary, Oregano, Pink Savory, Lemon Balm, and Saffron. The bioactive compounds were evaluated against key biological targets associated with hypertension and cardiovascular diseases, [...]

by Byron J. Hoogwerf

Received: 09 July 2024;  Published: 20 February 2025;  doi: 10.21926/obm.geriatr.2501299

Sarcopenia is more common in persons with type 2 diabetes mellitus (T2DM) than in persons without diabetes. There is overlap of some pathophysiologic features of sarcopenia and T2DM. In addition, the risk for sarcopenia is associated with common complications of T2DM including renal disease, cardiovascular disease and neuropathy. Glycemic control in T2DM may have some benefits on sarcopenia. The specific effects of glucose lowering agents on sarcopenia suggest that metformin, insulin, thiazolidinediones and GLP1 re [...]

by Van Anh Vu  , Joelle Nelson  , Helen Sweiss  , Reed Hall  , Holly Keyt  and Elisabeth Kincaide

Received: 29 January 2024;  Published: 03 July 2024;  doi: 10.21926/obm.transplant.2403220

Secondary hypogammaglobulinemia (HGG) from immunosuppression therapy in lung transplant recipients has been associated with increased mortality, morbidity and higher risk of infection. Intravenous immunoglobulin (IVIG) for the treatment of HGG post-lung transplant is not well studied with conflicting evidence regarding efficacy. This single-center, retrospective cohort study analyzed adult lung transplant recipients with HGG receiving ≥1 dose of IVIG 0.3-0.5 g/kg. Resolution of HGG (IgG > 600 mg/dL wi [...]