Table of Content

Open Access Original Research

The Dynamics of the Oceanic Air-Sea Boundary Layer

Received: 13 November 2022;  Published: 05 February 2023;  doi: 10.21926/aeer.2301018

Abstract

This paper presents a model for the similarity structure of the velocity profiles in air and water in the wave boundary layer, which provides predictions in terms of two parameters, F and R, of all its important properties, including the Charnock parameter, the surface drift velocity and the condition for the cancellation of the surface Stokes velocity by the surface current. The parameter, F, arises from the fetch variability of the wave field, and the parameter, R, arises from the duration variability of the wave [...]

969 6032

Open Access Review

Astrocyte-Neuron Interactions in the Neuroinflammatory Cascade of Traumatic Brain Injury

Received: 31 March 2025;  Published: 09 July 2025;  doi: 10.21926/obm.neurobiol.2503291

Abstract

Traumatic brain injury (TBI) is a significant public health concern, leading to substantial morbidity and mortality. While the primary injury is mechanical, the subsequent neuroinflammatory cascade plays a critical role in secondary injury and long-term neurological deficits. Astrocytes, the most abundant glial cells in the brain, play a key role in this cascade, interacting with neurons in a complex interplay that can both protect and exacerbate neuronal damage. This paper aims to provide a comprehensive overview [...]

1111 6026

Open Access Research Article

Phytomodification Effects of Visceral Lymph Node Aging

Received: 09 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.geriatr.2304257

Abstract

Lymph nodes are prioritized in protecting and ensuring endoecological safety at different periods of life, especially in retirement age. It destabilizes the structure and function of the lymphatic system and organs when aging increases the risk of comorbid conditions. This is a sign of age-related pathology. Improving lymph node function is an essential task in integrating gerontology and lymphology. The solution to this problem is possible with the help of a phytotherapeutic agent, which involves the evaluation of [...]

1069 6021

Open Access Opinion

The Curing of Crohn’s Disease

Received: 06 January 2019;  Published: 04 June 2019;  doi: 10.21926/obm.hg.1902021

Abstract

Using the therapeutic intervention points identified by the Hruska Postulate, the probability of curing Crohn’s disease through destroying the anti-MAP template is discussed.

1344 6017

Open Access Case Report

Unraveling and Expanding the Genotypic Spectrum of Kabuki Syndrome with Identification of de Novo Protein-Truncating Mutations in the KMT2D Gene: Insights into the Role of Premature Stop Codons in the Etiology of the Disorder

Received: 16 January 2025;  Published: 21 May 2025;  doi: 10.21926/obm.genet.2502294

Abstract

Kabuki Syndrome (KS) is a rare, multisystem congenital disorder with five foremost clinical manifestations encompassing dysmorphic facial characteristics, postnatal growth constraint, craniofacial/skeletal anomalies, mild to moderate intellectual disability, and dermatoglyphic abnormalities. We analyzed two unrelated Iranian patients suspected of having KS using whole-exome sequencing. An in silico analysis was performed to evaluate the potential effects of the discovered variants on the structure and function of t [...]

1036 6015

Open Access Case Report

Chromosome 7 Isodisomy in a Child with Silver-Russell Syndrome

Received: 19 March 2024;  Published: 24 June 2024;  doi: 10.21926/obm.genet.2402247

Abstract

Silver-Rusell syndrome is a rare genetic disease. There is evidence that the genetic causes of the disorder are heterogeneous, with predominant alterations in the imprinted regions of chromosomes 11 and 7, in addition to other genomic alterations, such as chromosomal structural aberrations, single nucleotide polymorphisms, copy number variations, and small insertions and deletions. The most prevalent clinical manifestations include prenatal and postnatal growth retardation, dysmorphic features, and feeding difficul [...]

945 6014

Open Access Review

Introduction to COVID-19 Vaccines and Kidney Transplant Recipient

Received: 03 August 2024;  Published: 24 February 2025;  doi: 10.21926/obm.transplant.2501236

Abstract

COVID-19 has presented considerable health hazards, particularly for immunocompromised persons, such as kidney transplant recipients. This population experiences increased susceptibility due to the immunosuppressive treatments necessary to avert organ rejection, potentially resulting in a diminished immune response to immunizations. The implementation of COVID-19 vaccinations has been essential in alleviating these dangers. Studies demonstrate differing levels of vaccine efficacy among kidney transplant recipients, [...]

724 6007

Open Access Research Article

Design and Management of Renewable Energy Systems for Isolated Communities with No Grid Connection

Received: 10 October 2024;  Published: 07 March 2025;  doi: 10.21926/jept.2501005

Abstract

The growing demand for energy and the need to reduce dependence on non-renewable sources have driven the research and application of sustainable technologies. In this context, an integrated solution that combines distributed energy generation from renewable sources, such as wind and hydro, with efficient management of household energy consumption is proposed. This study focuses on the hybrid renewable energy system simulation analysis designed to meet the demand of an off-grid household in a self-consumption mode. [...]

1179 6001

Open Access Case Report

Successful Treatment of a Pregnant Woman with Chronic Active Hepatitis B using Tenofovir Disoproxil Fumarate

Received: 23 June 2017;  Published: 27 July 2017;  doi: 10.21926/obm.hg.1703004

Abstract

(1) Background: Infection with hepatitis B virus (HBV) infection during pregnancy occasionally raises concerns, including acute exacerbation and the potential for mother-to-child transmission. (2) Case Report: Here, we present a case of a female patient with a chronic HBV infection who was treated with tenofovir disoproxil fumarate (TDF) and had a normal pregnancy and delivery. Furthermore, the use of TDF, HBV vaccination and passive immunization of her child with hyperimmune hepatitis B immunoglobulin successfully [...]

973 5996

Open Access Review

Using Technologies to Promote Adaptive Responding and Reduce Challenging Behaviors in Children with Autism Spectrum Disorder: A Selective Review

Received: 30 May 2024;  Published: 15 August 2024;  doi: 10.21926/obm.neurobiol.2403240

Abstract

The management and treatment of challenging behaviors in children diagnosed with Autism Spectrum Disorder (ASD) is a priority for caregivers, educators, and healthcare professionals. This selective review examined how different technologies were used to help manage challenging behaviors in children with autism, describing each technology's strengths, weaknesses, and applications. This paper aimed to provide accessible choices for caregivers, educators, and healthcare professionals, enabling them to make well-inform [...]

696 5989

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