by Tommy Sundqvist  , Lars Stenhammar  , Bo Tjellström  , Karl-Eric Magnusson  , Tore Midtvedt  , Elisabeth Norin  and Lotta Högberg

Received: 07 February 2020;  Published: 09 March 2020;  doi: 10.21926/obm.hg.2001043

by Byron J. Hoogwerf

Received: 09 July 2024;  Published: 20 February 2025;  doi: 10.21926/obm.geriatr.2501299

Sarcopenia is more common in persons with type 2 diabetes mellitus (T2DM) than in persons without diabetes. There is overlap of some pathophysiologic features of sarcopenia and T2DM. In addition, the risk for sarcopenia is associated with common complications of T2DM including renal disease, cardiovascular disease and neuropathy. Glycemic control in T2DM may have some benefits on sarcopenia. The specific effects of glucose lowering agents on sarcopenia suggest that metformin, insulin, thiazolidinediones and GLP1 re [...]

by Ramareddy V Guntaka

Received: 20 December 2018;  Published: 13 March 2019;  doi: 10.21926/obm.hg.1901014

Liver fibrosis leading to cirrhosis and cancer affects millions of people and causes thousands of deaths all over the world. Many signaling pathways could be targeted to block fibrosis but these are not successful. Reviewing recent literature and from our own studies we identified novel target, such as YB-1, which is implicated in inflammation, angiogenesis and accumulation of extracellular matrix (ECM). In addition we observed and showed that the end product of fibrosis, collagen gene, itself is a direct target fo [...]

by Tracy O'Halloran  , Jennifer Symonds  and Linda Bhreathnach

Received: 02 November 2023;  Published: 11 May 2024;  doi: 10.21926/obm.icm.2402026

This systematic review examined the impact of wellbeing interventions on the anxiety levels of children attending low-income schools. Studies, published between January 2000 and April 2022, were included if they had samples of school aged children attending low-income schools who were given a universal school-based wellbeing intervention. Ten databases were searched systematically to identify 542 records. After title and abstract screening, 43 records remained for full text screening, and of these studies, 10 met i [...]

by Navid Khaleghimoghaddam  and Sara Arzhangi

Received: 11 April 2025;  Published: 31 July 2025;  doi: 10.21926/obm.neurobiol.2503294

The acoustic design of indoor environments encompassing spatial configuration, material properties, and sound absorption significantly influences auditory perception and psychological well-being. This study examines the interaction between architectural acoustics, musical stimuli, and neural responses within a controlled therapeutic context, focusing on their effects on stress reduction and relaxation. Electroencephalography (EEG) was utilized to measure brain activity in 24 participants exposed to six musical inst [...]

by A. Maya Kaye

Received: 14 October 2023;  Published: 27 April 2024;  doi: 10.21926/obm.icm.2402024

Fueled by decreased state support, economic pressures, and a growing emphasis on academic capitalism, higher education in the United States faces significant challenges. These shifts have fostered fast-paced, competitive environments, impacting the quality and equity of faculty-student mentoring in graduate programs, particularly for Black, Indigenous, People of Color (BIPOC), and first-generation students. This article proposes a novel framework, the compassion-focused mentoring conceptual model (CFM-CM), to addre [...]

by Roy G Beran

Received: 01 July 2022;  Published: 13 September 2022;  doi: 10.21926/obm.geriatr.2203204

This paper examines sleep disorders in older people, focusing on Parkinson’s disease (PD). It defines PD and explores those conditions associated with sleep disorders and their relationship to PD. It identifies specific conditions which cause sleep disoders in patients with PD, namely: REM sleep behaviour disorder (RDB) which may be a precursor to PD; obstructive sleep apnoea (OSA) which is very prevalent amongst people with PD; depression and mood disorders which both increase with age and are more common in peopl [...]

by Minggao Zhou  , Yongren Feng  , Yongzeng Xue  , Yanmin Zhou  , Yongchao Chen  and Wilson C. Chin

Received: 12 April 2023;  Published: 27 November 2023;  doi: 10.21926/jept.2304038

An early formation tester operating a “sink probe” that extracts fluids from the borehole, also measures pressures at its location; pressures are additionally collected at two passive sensors, one situated 180 deg away and the second about meter axially. These positions are not conducive to accurate permeability predictions, since pressure transient signals used for inverse analysis attenuate very rapidly. Closer probe spacings offer formation evaluation advantages at low mobilities because Darcy pressure dissipati [...]

by OBM Genetics Editorial Office

Received: 17 February 2022;  Published: 22 February 2022;  doi: 10.21926/obm.genet.2201148

by Leonid Dvorkin  , Vadim Zhitkovsky  and Ruslan Makarenko

Received: 12 January 2023;  Published: 24 February 2023;  doi: 10.21926/rpm.2301009

The article proposes a method that considers the parameters of heat and moisture treatment of concrete when designing its composition. Based on the analysis of experimental data, formulas are proposed that allow taking into account the type and characteristics of cement, the characteristics of aggregates, the effect of temperature and duration of steaming, and the water-cement ratio. Graphs and nomograms have been obtained, which makes it possible to simplify the calculation procedure according to the proposed meth [...]