Arginine and Histidine-modified Layered Double Hydroxides Facilitate Transgene Expression in Cancer Cells in Vitro
Abstract
1475 7119
Arginine and Histidine-modified Layered Double Hydroxides Facilitate Transgene Expression in Cancer Cells in VitroAbstract
Layered double hydroxides (LDHs) have interesting properties and structures that enable them to carry nucleic acids, such as deoxyribonucleic acid (DNA). This study synthesized LDHs using the co-precipitation method and functionalized with the amino acids arginine (Arg) and histidine (His) to promote proton-sponge activity for enhanced transgene expression. The LDHs were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), and nanoparticle tracking analysis (NTA). The interaction of [...] 1475 7119 |
Young Adult’s Mental Health Literacy in Relation to Depression and Their Attitudes Towards Complementary Medicine PracticeAbstract
Depression and mental health-related issues are increasingly prevalent in young adolescents and adults and so is the use of Complementary Therapies (CTs) to treat depression. Systematic reviews have found that, of all CTs, acupuncture, exercise, and the herbal remedy St John’s Wort have the greatest amount of evidence for efficacy in treating depression. We aimed to assess Mental Health Literacy (MHL) levels in the treatment of depression and Complementary Therapy’s (CT) usage in adolescents and adults. Surveys wer [...] 1280 7119 |
Platelet Function in Experimental Models of Liver CirrhosisAbstract
(1) Background: Platelet function is commonly altered in liver cirrhosis. In experimenta models of liver cirrhosis we have analyzed the mechanisms of this defective function.
(2) Methods: Experiments were performed in a model of liver cirrhosis by bile duct-ligation in washed platelets by means of fluorescence spectroscopy with fura-2.
(3) Results: We have found several alterations compatible with the existence of a hyperaggregatory state. These alterations are related to a defective platelet calcium handling, spec [...] 1446 7117 |
Photodegradation of Polyethersulfone (PES), Polyvinylidene Fluoride (PVDF) and Polymethyl Methacrylate (PMMA) Microplastics via a Metal Organic Framework Namely ZIF-8/ZnO/CAbstract
The aim of this study was to photodegrade the Polyethersulfone (PES), Polyvinylidene fluoride (PVDF) and Polymethyl methacrylate (PMMA) microplastics using Zeolitic imidazolate framework-8/Zinc oxide/Carbon (ZIF-8/ZnO/C) nanocomposite generated under laboratory conditions. The produced nanocomposite was analysed using X-Ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Photo Spectroscopy (XPS), Scanning Electron Microscope (SEM), Diffuse reflectance UV-vis spectra (DRS) and Electron Spin R [...] 1326 7109 |
The Impact of Vitamin D on Type 2 Diabetes Mellitus: Exploring Its Role in Glucose Metabolism and Insulin SensitivityAbstract
Vitamin D, a fat-soluble secosteroid, plays a pivotal role beyond its functions in calcium and bone homeostasis. Emerging evidence suggests its involvement in glucose metabolism and insulin sensitivity, thus influencing the pathophysiology of Type 2 Diabetes Mellitus (T2DM). For the current review, a search was conducted across four major databases: PubMed, Embase, Google Scholar, and Web of Science. The aim was to identify relevant studies and clinical trials, published in English, reporting the mechanistic insigh [...] 1236 7108 |
Comparison of Sputum and Oropharyngeal Microbiome Compositions in Patients with Non-Small Cell Lung Cancerby
Abstract
Recent findings indicate that the microbiota is involved in the development of lung cancer by inducing inflammatory responses and generating genome damage. This study aimed to compare sputum microbiomes from the mouth and oropharynx in non-small cell lung carcinoma (NSCLC) patients. A second goal was to search for bacterial taxonomic units that behave differently in the microbiome of NSCLC patients and healthy subjects. In the study, the taxonomic composition of the sputum and oropharyngeal microbiomes of 23 male p [...] 1198 7100 |
COVID-19’s Psychological Threats and Future Career Anxiety among University StudentsAbstract
The COVID-19 pandemic brought different intolerable and uncomfortable situations that ruined the students' academic performance, career opportunities, and social lives through depression, anxiety, fear, uncertainty, and mental illness. In this study, we examined the psychological threats of the COVID-19 among Egypt’s public-sector university students. We employed quantitative methods in this study and used a questionnaire to collect cross-sectional data. The Structural Equation Modeling (SEM) results show that Fear [...] 822 7095 |
Impact of COVID-19 on Chile's Energy Transition Policies and Goalsby
Abstract
Because of climate change, greenhouse gas (GHG) emissions have increased, leading to the implementation of energy transition policies. Countries have adopted the Paris Agreement to curb the effects of climate change. The emergence of COVID-19 in 2020 led to the application of different measures to stop its transmission. This study evaluated the effects of COVID-19-related restrictions (such as quarantine and mobility restriction) in Chile during the first wave on compliance with the country's energy transition poli [...] 1210 7078 |
Looking Beyond the Mother: Investigating Relationship Characteristics and Postpartum Depression Risk FactorsAbstract
Postpartum depression (PPD) affects a notable number of women. While many of the risk and protective factors for PPD are specific to the mother, there are also factors that are related to the partner. However, the partner is often overlooked when assessing the landscape of PPD and potential treatment programs. This study sought to expand the knowledge on partner perceptions during the perinatal period. This online, cross-sectional survey of fathers who were in relationships with mothers who had given birth within t [...] 1128 7077 |
Highlights of Complementary and Alternative Medicine in Nervous System Conditions: An Interview with Dr. James David Adams, Jr.Abstract
Highlights of Complementary and Alternative Medicine in Nervous System Conditions: An Interview with Dr. James David Adams, Jr. 1202 7061 |
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