Table of Content

Open Access Original Research

Identification of Potential Predictive and Diagnostic Urinary Biomarkers for Acute Rejection in Renal Transplant Recipients: A Proteomics Study

Received: 25 May 2023;  Published: 07 July 2023;  doi: 10.21926/obm.transplant.2303191

Abstract

Acute rejection (AR) is one of the main predictors of long-term survival of allograft. The development of noninvasive diagnostic biomarkers of AR is an unmet need for the timely detection. This study aimed to identify novel detective biomarkers of AR by analyzing the urine proteome profile of transplant patients. Forty-two transplant patients including 30 biopsy-proven AR patients (including antibody and T-cell mediated rejection) and 12 transplant patients with stable renal function (control group) were enrolled. [...]

1088 6635

Open Access Editorial

Acknowledgement to Reviewers of OBM Geriatrics in 2021

Received: 06 January 2022;  Published: 06 January 2022;  doi: 10.21926/obm.geriatr.2201186

Abstract

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition [...]

1004 6633

Open Access Review

Mental Health Disorders Following Exposure to Endocrine Disruptor Chemicals

Received: 27 October 2024;  Published: 18 April 2025;  doi: 10.21926/obm.neurobiol.2502285

Abstract

There is growing scientific concern regarding how endocrine-disrupting chemicals (EDCs) impact central nervous system (CNS) disorders. Both anecdotal and preclinical studies suggest a link between EDC exposure and major depressive disorder (MDD), potentially leading to neurodegenerative outcomes. EDCs primarily exhibit their biological effects by interacting with hormone receptors. Nonetheless, there is scientific evidence pointing to dysfunction in the hypothalamic-pituitary-gonadal-adrenal axis, which is linked t [...]

878 6629

Open Access Concept Paper

Compassion-Focused Mentoring: An Antidote to Adverse Faculty-Student Mentoring Outcomes?

Received: 14 October 2023;  Published: 27 April 2024;  doi: 10.21926/obm.icm.2402024

Abstract

Fueled by decreased state support, economic pressures, and a growing emphasis on academic capitalism, higher education in the United States faces significant challenges. These shifts have fostered fast-paced, competitive environments, impacting the quality and equity of faculty-student mentoring in graduate programs, particularly for Black, Indigenous, People of Color (BIPOC), and first-generation students. This article proposes a novel framework, the compassion-focused mentoring conceptual model (CFM-CM), to addre [...]

1083 6615

Open Access Editorial

Acknowlegement to Reviewers of OBM Geriatrics in 2020

Received: 04 January 2021;  Published: 06 January 2021;  doi: 10.21926/obm.geriatr.2101149

Abstract

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition [...]

1428 6607

Open Access Research Article

An Efficient Method for Micropropagation of Red-List Herbaceous Plant Species (Hedysarum cretaceum)

Received: 11 November 2022;  Published: 20 July 2023;  doi: 10.21926/obm.genet.2303187

Abstract

Hedysarum cretaceum Fisch is a critically endangered herbaceous species with high ornamental and phytomeliorative properties; thus, it needs urgent conservation and protection methods to conserve. In the present study, an efficient method for microtonal propagation of H. cretaceum is developed. The seed sterilization was optimized as treatment with 96% alcohol (2 min) and burned (1 sec) through a burner flame. Murashige and Skoog (MS) medium with the addition of 0.5 mg/L 6-Benzylaminopurine (BAP) (shoots per explan [...]

1041 6604

Open Access Review

The Impact of Wellbeing Interventions on the Anxiety Levels of Children Attending Low-Income Schools: A Systematic Literature Review

Received: 02 November 2023;  Published: 11 May 2024;  doi: 10.21926/obm.icm.2402026

Abstract

This systematic review examined the impact of wellbeing interventions on the anxiety levels of children attending low-income schools. Studies, published between January 2000 and April 2022, were included if they had samples of school aged children attending low-income schools who were given a universal school-based wellbeing intervention. Ten databases were searched systematically to identify 542 records. After title and abstract screening, 43 records remained for full text screening, and of these studies, 10 met i [...]

1243 6603

Open Access Original Research

Predicting Suicide Risk among South African University Students: Optimal Cutoff Score for the Center for Epidemiological Studies Depression Scale

Received: 28 April 2023;  Published: 03 July 2023;  doi: 10.21926/obm.neurobiol.2303173

Abstract

University students have been identified as a particularly vulnerable group for adverse mental health outcomes owing to the distinctive implications of the COVID-19 prevention measures on the educational sector. Even prior to the pandemic, university students were identified as being at increased risk for adverse mental health outcomes and suicidality. Although various factors can enhance the risk of suicide, one of the strongest predictors of suicidality is the presence of depressive symptomology. The current stud [...]

1029 6597

Open Access Case Report

Sleep Disorders in Older People with Special Focus on Parkinson’s Disease

Received: 01 July 2022;  Published: 13 September 2022;  doi: 10.21926/obm.geriatr.2203204

Abstract

This paper examines sleep disorders in older people, focusing on Parkinson’s disease (PD). It defines PD and explores those conditions associated with sleep disorders and their relationship to PD. It identifies specific conditions which cause sleep disoders in patients with PD, namely: REM sleep behaviour disorder (RDB) which may be a precursor to PD; obstructive sleep apnoea (OSA) which is very prevalent amongst people with PD; depression and mood disorders which both increase with age and are more common in peopl [...]

1142 6593

Open Access Research Article

Accounting for the Influence of Heat-Moisture Treatment Mode When Designing Concrete Composition

Received: 12 January 2023;  Published: 24 February 2023;  doi: 10.21926/rpm.2301009

Abstract

The article proposes a method that considers the parameters of heat and moisture treatment of concrete when designing its composition. Based on the analysis of experimental data, formulas are proposed that allow taking into account the type and characteristics of cement, the characteristics of aggregates, the effect of temperature and duration of steaming, and the water-cement ratio. Graphs and nomograms have been obtained, which makes it possible to simplify the calculation procedure according to the proposed meth [...]

1068 6593

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