Table of Content

Open Access Original Research

IFN-Based and IFN-Free Direct-Acting Antiviral Drug Treatments for Acquired Hepatitis C Virus in Post-Transplant Recipients

Received: 08 February 2017;  Published: 06 April 2017;  doi: 10.21926/obm.hg.1702003

Abstract

Background: Hepatitis C virus (HCV) infection frequently occurs in recipients of liver or kidney transplants (LT/KT). Interferon (IFN)-based therapies are used to treat HCV, but their efficacy is low. Methods: We report 24 patients who received HCV therapy after LT/KT. Design, Setting, and Participants-Twelve LT and 12 KT recipients (median age, 59 years; 15 males; 21 serological type 1) were enrolled, of whom eight (six with LT) were treated with IFN-based therapy. Twelve received direct-acting antiviral drugs [ [...]

1057 6764

Open Access Original Research

Modeling Water Quality of AMD along the Flow Path

Received: 30 October 2022;  Published: 28 February 2023;  doi: 10.21926/aeer.2301023

Abstract

The water balance is severely disturbed in post-mining landscapes like Lusatia/Germany. Mine waters (amd) enter the environment and spread in groundwater and surface waters. Groundwater containing high amounts of pyrite weathering products flows into receiving waters due to lignite mining for several years. The Chair of Wassertechnik & Siedlungswasserbau at the Brandenburg University of Technology Cottbus-Senftenberg/Germany has developed a subsurface rehabilitation method using microbial sulfate reduction over the [...]

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Open Access Editorial

Acknowledgement to Reviewers of OBM Geriatrics in 2021

Received: 06 January 2022;  Published: 06 January 2022;  doi: 10.21926/obm.geriatr.2201186

Abstract

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition [...]

1081 6760

Open Access Case Report

Therapeutic Use of Auto-Induced Cognitive Trance in a Chronic Pain Setting: A Case Study Using Mixed Methodology

Received: 14 August 2024;  Published: 05 March 2025;  doi: 10.21926/obm.icm.2501012

Abstract

Auto-induced cognitive trance (AICT) is a method for voluntarily entering modified state of consciousness. The therapeutic implications of AICT are still unknown. Since complementary approaches based on modified states of consciousness are recognized to be beneficial for patients suffering from chronic pain (e.g., hypnosis, meditation), we here present the first case report of a 68-year-old man with a long history of chronic pain linked to an open Spina Bifida L4-L5, who used AICT to improve his health condition. S [...]

1092 6756

Open Access Editorial

Treasure Your Exceptions and Submit These to OBM Genetics

Received: 16 January 2017;  Published: 10 February 2017;  doi: 10.21926/obm.genet.1701001

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Open Access Review

Low Prevalence of Spontaneous Bacterial Peritonitis in Ambulatory Asymptomatic Cirrhotic Patients: Consequences in Patients’ Care

Received: 21 August 2019;  Published: 15 April 2020;  doi: 10.21926/obm.hg.2002045

Abstract

The literature on the prevalence of spontaneous bacterial peritonitis (SBP) in cirrhotic outpatients who visited the hospital for therapeutic abdominal paracentesis was reviewed in order to assess the usefulness of urinary strips in this setting. The authors reviewed the studies published as peer-reviewed articles on the prevalence of SBP in ambulatory outpatients who visited the hospital for therapeutic paracentesis. Five such studies were available in the literature. It was found that the prevalence of SBP was in [...]

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Open Access Case Report

Interstitial 1p36 Deletion Syndrome Encompassing CAMTA1 Gene: A Case Report

Received: 29 November 2024;  Published: 05 February 2025;  doi: 10.21926/obm.genet.2501284

Abstract

Deletion of chromosome 1p36 encompassed various genes; however, the role of the CAMTA1 gene in the 1p36 region is less investigated. We report a child with developmental delay, a history of congenital heart abnormality, self-injurious behavior, nystagmus, and facial dysmorphism. Chromosomal microarray revealed a 257.2 kb deletion of chromosome 1p36.31, with CAMTA1 as the only involved gene. We explore overlapping clinical features of both chromosome 1p36 deletion and CAMTA1 intragenic deletion, including intellectu [...]

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Open Access Research Article

An Efficient Method for Micropropagation of Red-List Herbaceous Plant Species (Hedysarum cretaceum)

Received: 11 November 2022;  Published: 20 July 2023;  doi: 10.21926/obm.genet.2303187

Abstract

Hedysarum cretaceum Fisch is a critically endangered herbaceous species with high ornamental and phytomeliorative properties; thus, it needs urgent conservation and protection methods to conserve. In the present study, an efficient method for microtonal propagation of H. cretaceum is developed. The seed sterilization was optimized as treatment with 96% alcohol (2 min) and burned (1 sec) through a burner flame. Murashige and Skoog (MS) medium with the addition of 0.5 mg/L 6-Benzylaminopurine (BAP) (shoots per explan [...]

1087 6731

Open Access Review

Practices Used in Health and Social Services for the Management of Mistreatment Situations towards Adults in a Context of Gender and Sexual Diversity: A Scoping Review

Received: 18 December 2023;  Published: 17 July 2024;  doi: 10.21926/obm.geriatr.2403282

Abstract

Research indicates that adults in the context of gender and sexual diversity (GSD) experienced more violence and discrimination than the rest of the population. GSD refers to all the diversities of sexual characteristics, sexual orientations and gender identity of a person or a group. To encourage the use of evidence-based interventions in health and social services, it is important to extrapolate from the scientific literature how mistreatment situations are managed in this context. A scoping review was conducted [...]

1138 6729

Open Access Original Research

Predicting Suicide Risk among South African University Students: Optimal Cutoff Score for the Center for Epidemiological Studies Depression Scale

Received: 28 April 2023;  Published: 03 July 2023;  doi: 10.21926/obm.neurobiol.2303173

Abstract

University students have been identified as a particularly vulnerable group for adverse mental health outcomes owing to the distinctive implications of the COVID-19 prevention measures on the educational sector. Even prior to the pandemic, university students were identified as being at increased risk for adverse mental health outcomes and suicidality. Although various factors can enhance the risk of suicide, one of the strongest predictors of suicidality is the presence of depressive symptomology. The current stud [...]

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