by Addisu Yeshambel  , Tamiru Alene  , Getachew Asmare  , Gedion Asnake  , Wallilign Anmut  , Kelemu Abebe  and Belete Birhan

Received: 08 December 2022;  Published: 12 February 2023;  doi: 10.21926/obm.neurobiol.2301154

Perinatal loss is the most painful and unanticipated experience for those who conceived and it is a major global concern worldwide, especially in developed countries like Ethiopia. Women who lost their pregnancy are believed to be at higher risk of developing severe grief following a loss. To reduce the risk of complications after perinatal loss, healthcare providers need to appreciate the grieving process and identify grief factors in mothers for early copying and to be managed promptly by providing adequate emoti [...]

by Ajay Risal  , Dipak Kunwar  and Barsha Shrestha

Received: 21 December 2023;  Published: 08 February 2024;  doi: 10.21926/obm.geriatr.2401268

This paper discusses the impact of Depression on the aging population. It also tries to explore the psychosocial risk factors and burden associated with geriatric depression in low-and-middle-income (LAMI) countries. Nepal, a South Asian developing country, is resource-poor and research-naïve. Research, in general, and mental health studies, in particular, are the least prioritized in this country. The lack of culturally adapted psychiatric inventories is one of the possible reasons for the low number of mental hea [...]

by Michael J Eiswerth  and Joel Wedd

Received: 30 November 2024;  Published: 17 April 2025;  doi: 10.21926/obm.transplant.2502247

The prevalence of alcohol use disorder (AUD) and alcohol-related liver disease (ALD) has increased in the last two decades. ALD is currently the most common indication for both waitlist additions and liver transplant (LT) in the United States, including alcohol-associated cirrhosis, alcohol-associated hepatitis (AH), and acute-on-chronic liver failure (ACLF). ALD also has a significant global disease burden. LT in ALD is a complex paradigm that poses both medical and ethical challenges, requiring a multidisciplinar [...]

by Yulia Aleksandrova  , Alexey Semakov  , Dmitry Tsypyshev  , Kirill Chaprov  , Sergey Klochkov  and Margarita Neganova

Received: 23 August 2023;  Published: 09 January 2024;  doi: 10.21926/obm.neurobiol.2401207

Here, we report the results of an investigation of the neuroprotective effects of securinine with tryptamine conjugate-allomargaritarine (2b), previously selected as the leading compound among a wide range of natural derivatives. 2b was synthesized from securinine using various Lewis acids as catalysts. In addition to the antioxidant and cytoprotective properties previously shown for 2b, in this work, in vitro analysis of the biological activity of the compound demonstrated that this conjugate is also able to influ [...]

by Sopnil Ahmed Jahin  , Biswajit Das  , Adrita Abdullah  , Sadia Akter  , Mohammad Abu Kawsar Sarower Siddique  and Mohammad Anwar Hossain

Received: 02 August 2024;  Published: 01 November 2024;  doi: 10.21926/obm.genet.2404270

Drought and phosphorus (P) deficiency stress are two significant natural abiotic stresses restricting rice growth and yield worldwide. Developing rice varieties tolerant to drought and low P stress is crucial for sustainable agricultural production. To address these issues, two separate experiments were conducted using selected advanced rice breeding lines to study the impact of drought and low P stress on yield-attributing traits. The first experiment evaluated the drought stress tolerance of five advanced lines ( [...]

by Suman Roy

Received: 27 September 2022;  Published: 03 January 2023;  doi: 10.21926/rpm.2301001

Increased occurrence of dynamic loading on bridge piers caused by seismic, blast and vehicular impact incidences have been increasingly reported. Statistical data shows that while seismic and blast have received significant attention in the literature despite the frequency of occurrence of vehicular impact is remarkably higher. Unfortunately, pier damage caused by high velocity vehicle impact contemplates a little consideration. With the newer construction methods like accelerated bridge construction (ABC) and its [...]

by Gregor Reid  , Azza A. Gadir  , Scarlett Puebla Barragan  and Raja Dhir

Received: 11 December 2020;  Published: 01 February 2021;  doi: 10.21926/obm.hg.2101055

The human intestinal microbiota represents a complex microbial community that plays an essential role in the maintenance of host health. Over the last decade, metagenomic and metabolomic analyses have revealed the influence of intestinal microbial diversity and composition on a range of biological functions in the host. While overall taxonomic composition of the intestinal microbiome is informative, changes in spatial dynamics within the community also have profound biological significance as microbial functions ar [...]

by Karine Dornela Rosa  , Tara Rava Zolnikov  , Rodrigo Souza Leite  , Sérgio Caldas  , Job Alves de Souza Filho  , Raquel Sampaio Jacob  and Marcos Paulo Gomes Mol

Received: 05 May 2022;  Published: 11 July 2022;  doi: 10.21926/aeer.2203028

Visceral leishmaniasis (VL) is a vector-borne disease that is caused by the protozoan Leishmania infantum and transmitted to humans and other mammals through the bites of infected female sandflies. VL has been prevalent in Minas Gerais, Brazil, since the 1940s. As the vector completes its reproductive cycle in the soil with organic matter, the association between the occurrence of VL and unimproved solid waste disposal sites has been investigated. Thus, in this study, we analyzed the relationship of waste disposal [...]

by Hannah Lewandowski  , Lindsay Crawford  and Paul D. Loprinzi

Received: 13 April 2019;  Published: 25 June 2019;  doi: 10.21926/obm.icm.1902039

Acute exercise may enhance episodic memory recall, or the retrospective recall of an event or episode due to exercise-induced neuronal excitability and ensuing long-term potentiation. Of interest to this paper is the potential effects of acute exercise on memory interference, when the interfering stimuli occurs at the same time as the target stimuli. A three-arm, parallel-group randomized controlled intervention was employed. Participants (N=50) were randomized into one of three groups, including 1) Interference + [...]

by Katherine W. Zerebiec  , Magalie Carey  , Noah Kolb  , Tracy Lamoy  , Divyanshu Dubey  and Michael K. Hehir

Received: 15 November 2022;  Published: 08 May 2023;  doi: 10.21926/obm.neurobiol.2302168

A 46-year-old, previously healthy woman presented via telemedicine with 14 months of progressive asymmetrical weakness, numbness, paresthesias and tremors. History and clinical exam findings suggested a peripheral etiology resembling a variant CIDP presentation. Electrodiagnostic testing identified only one motor nerve with signs of demyelination; the remainder of motor and sensory nerves were unable to be evoked. MRI showed diffuse enhancement of the trigeminal nerve and cauda equina. CSF revealed albuminocytologi [...]