Table of Content

Open Access Review

Conventional and Future Therapies for Crohn's Disease

Received: 20 May 2019;  Published: 14 August 2019;  doi: 10.21926/obm.hg.1903032

Abstract

Crohn's disease is part of a group of diseases termed inflammatory bowel disease. Guidelines have long advocated the use of steroids for acute flare up and Current goals of treatment include enhancing long-lasting remission, preventing relapse, reducing the need for surgery, preventing complications and slowing disease progression. No cure currently exists for the disease. Traditionally, the clinical approach to treatment has been symptom-based where patients have had to ‘earn’ their next treatment escalation. Howe [...]

1429 8951

Open Access Original Research

Dancing Exercise Enhances Metabolic Functions via Hypercortisolism-Mediated Inhibition of Inflammatory Cytokines in Healthy Adult Volunteers

Received: 04 December 2023;  Published: 27 February 2024;  doi: 10.21926/obm.icm.2401015

Abstract

Regular physical activity has been proven to improve metabolism, slow aging, and decrease the likelihood of various health conditions such as obesity, type 2 diabetes, and cardiovascular disorders. Hence, dancing was evaluated for its effects on cardiovascular, liver enzymes, and biochemical markers among healthy adults. Forty (40) healthy adults (20-40 years old) were chosen for the study, with an average age calculated. Those with certain health conditions or habits were not allowed to participate. Twenty (20) me [...]

1352 8946

Open Access Original Research

Predictive Factors of Response to Mindfulness-Based Cognitive Therapy (Mbct) for Patients with Depressive Symptoms: The Machine Learning’s Point of View

Received: 23 August 2022;  Published: 28 December 2022;  doi: 10.21926/obm.icm.2204058

Abstract

While there is abundant literature on the benefits of Mindfulness-Based Interventions (MBI), data about factors associated with their Efficiency are scarce. Our study attempts to determine the moderators of efficacy and adherence in Mindfulness-Based Cognitive Therapy (MBCT) with a machine learning analysis. Seventy-six psychiatric outpatients at “university hospital mental health service” had a prescription for MBCT from their referring psychiatrist. They suffer from various psychiatric illnesses with [...]

1404 8944

Open Access Original Research

Haplo-Insufficiency or Knockout of the Serotonin Transporter Does not Affect Heroin Self-Administration but Decreases BDNF in the Frontal Cortex

Received: 01 February 2018;  Published: 07 June 2018;  doi: 10.21926/obm.neurobiol.1802010

Abstract

(1) Background: Drug addiction places a heavy burden on those affected by it but only a small percentage of individuals (~20%), regardless of their drug of abuse, go on to develop the compulsive behaviours that define drug addiction. Clinical studies have shown that genetic variations that reduce serotonin transporter (SERT) activity increase the vulnerability to developing a variety of psychiatric disorders such as depression, anxiety and drug addiction. (2) Methods: To investigate the influence of reduced SERT fu [...]

1653 8944

Open Access Opinion

Doing Brief Work, Slowly: Compassion as Intervention in Behavioral Medicine

Received: 20 March 2019;  Published: 18 June 2019;  doi: 10.21926/obm.icm.1902037

Abstract

Integration of behavioral health consultants and specialists into medical settings has accelerated the development of evidenced-based practices for an array of problems and concerns common to behavioral medicine. Though these treatments have shown to be beneficial for those that engage in protocols, attrition remains high. With an emphasis in directed problem solving and skill building, many brief treatments leave little room for compassion, validation, and understanding. This article explores this trend and advoca [...]

1984 8942

Open Access Editorial

Liver Transplantation in Pediatrics

Received: 15 May 2020;  Published: 18 May 2020;  doi: 10.21926/obm.transplant.2002111

1994 8942

Open Access Review

Rare Causes of Acute Pancreatitis: Drugs, Eosinophilia, and Autoimmunity

Received: 15 March 2019;  Published: 29 August 2019;  doi: 10.21926/obm.hg.1903034

Abstract

Background: Among the rarest causes of acute pancreatitis, in addition to the drugs (DIAP), there are eosinophilic pancreatitis (EP) and autoimmune pancreatitis (AIP). Methods: we have researched on PUBMED the descriptions of clinical cases of eosinophilic pancreatitis appeared from 1990 to February 2019 and those related to new drugs responsible for acute pancreatitis. Results: we found about thirty reports of eosinophilic pancreatitis associated or not with hypereosinophilia and gastro-intestinal manifestations. [...]

1387 8941

Open Access Review

The Association between Uric Acid Level and Ischemic Stroke

Received: 11 July 2023;  Published: 16 January 2024;  doi: 10.21926/obm.neurobiol.2401209

Abstract

Stroke is the second and third leading cause of death and disability, respectively, all over the world. It seriously affects patients' lives and brings huge burdens to their families. Ischemic stroke accounts for most of the stroke cases. In the absence of any effective treatment, prevention measures through controlling the risk factors for ischemic stroke become crucial. While uric acid has been reported as an essential risk factor for ischemic stroke, researchers hold inconsistent views regarding the specific ass [...]

1487 8939

Open Access Concept Paper

Induction into Browning’s Strategy: Suggestions for Family Therapy

Received: 11 April 2022;  Published: 25 July 2022;  doi: 10.21926/obm.icm.2203029

Abstract

The authors attempted to operationalize the clinical work of strategic theorist and expert family therapist, Scott Browning. Strategic therapy takes the position that a client is stuck, not necessarily sick. This focus encourages the clinician to create alternative perspectives such that a client learns to consider a problem from a new lens. Milton Erickson, a progenitor of strategic thinking, used hypnosis and paradox to nudge clients toward a useful alternative perspective [1]. The present article examined three [...]

1519 8938

Open Access Case Report

Case of Lung Transplantation in a Recipient with Emphysema: Importance of Determining Alpha 1-Antitrypsin Deficiency Status for Lung Transplantation

Received: 18 April 2018;  Published: 16 July 2018;  doi: 10.21926/obm.transplant.1803015

Abstract

Here we present a case of a lung transplant recipient with alpha 1-antitrypsin deficiency as well as conducted a retrospective review of the United Network for Organ Sharing (UNOS) database from 1990 – 2016 specifically grouping patients with alpha-1 antitrypsin deficiency (A1ATD) and chronic obstructive pulmonary disease (COPD).

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