Haplo-Insufficiency or Knockout of the Serotonin Transporter Does not Affect Heroin Self-Administration but Decreases BDNF in the Frontal Cortex
Abstract
1509 8580
Haplo-Insufficiency or Knockout of the Serotonin Transporter Does not Affect Heroin Self-Administration but Decreases BDNF in the Frontal CortexAbstract
(1) Background: Drug addiction places a heavy burden on those affected by it but only a small percentage of individuals (~20%), regardless of their drug of abuse, go on to develop the compulsive behaviours that define drug addiction. Clinical studies have shown that genetic variations that reduce serotonin transporter (SERT) activity increase the vulnerability to developing a variety of psychiatric disorders such as depression, anxiety and drug addiction. (2) Methods: To investigate the influence of reduced SERT fu [...] 1509 8580 |
Modeling CO2 and N2 Permeation through Mixed Matrix Membranes Containing Oxygenated Carbon Nanotubes Dispersed in PolysulfoneAbstract
Mixed matrix membranes (MMMs) consist of a polymeric phase and a dispersed solid filler such as zeolites or carbon nanotubes. We prepared symmetric and asymmetric polysulfone-based MMMs containing functionalized multi-walled carbon nanotubes (MWNT-O) for CO2/N2 separation. Maxwell’s model was used to predict the permeabilities of MMMs. The permeability achieved using the model exhibited a good fit of the model in symmetric MMMs, especially for CO2. This can be potentially attributed to the high affinity of th [...] 1816 8578 |
Three Inspiring Review Articles on Photobiomodulation: Update 2021Abstract
Photobiomodulation (PBM) is an accurate term for an effective and important application of light in medicine (such as in photomedicine). Three review articles of authors from the International Society of Medical Laser Applications (ISLA-Transcontinental) on the topic of PBM with a total of 116 printed pages, published in one renowned journal of molecular sciences with an impact factor of 13.668, are presented in the current review. The main topics are PBM, probiotics, curcumin, and arthritis. PBM can modulate cellu [...] 1824 8578 |
Rejuvenating the Skin: The Role of Macro and Microalgae in Preventing AgingAbstract
The increasing consumer demand for cosmetic products has led to the widespread use of synthetic substances, which are inexpensive and readily available but can sometimes harm the skin and body. Examples include hydroxybenzoic acid esters (parabens) and phthalates, which are considered endocrine disruptors, and synthetic fragrances that may cause irritation or allergies. Consequently, there has been a shift in consumer preferences towards natural cosmetic products. In response to this demand and the expanding market [...] 993 8577 |
Aspiration of Gastrointestinal Material and Induction of Fibronectin Expression in Lung Transplant Recipients: Implications for Early Airway Remodelingby
Abstract
Background: Gastroesophageal reflux disease has been associated with the development of chronic lung allograft dysfunction following lung transplantation. While the mechanisms are unclear, it is postulated that microaspiration of gastrointestinal material (GIM) leads to inflammation and airway remodeling that culminates in obliterative bronchiolitis. As the expression of the matrix glycoprotein fibronectin has been shown to be an early marker of this fibroproliferative process, its induction could suggest a causal [...] 1442 8561 |
The Nexus between Energy Poverty and Environmental Change in ZimbabweAbstract
Over the years, energy poverty has been seen as a major struggle in Zimbabwe and globally. This paper tries to find the relationship between energy poverty and environmental change. Ecological footprint represents a degradation in this paper. The findings showed an insignificant relationship between renewable energy and ecological footprint in Zimbabwe. This study employs the ARDL technique. This study employs time series data from 1990-2021. This study uses the ARDL framework to get robust results. The ARDL bound [...] 1599 8560 |
Left Atrial Systolic Force in Hypertensive Patients with Left Ventricular Hypertrophy: A Predictor of Incident Atrial Fibrillation. The LIFE Studyby
Abstract
It remains unknown whether left atrial systolic force (LASF), a measure of left atrial function, can be used as a predictor of new-onset atrial fibrillation (NOAF). Furthermore, the effect of the treatment with atenolol and losartan on LASF is unclear. A total of 758 patients without atrial fibrillation at baseline were enrolled from the Losartan Intervention For Endpoint (LIFE) reduction in hypertension echocardiography sub-study. Participants of the LIFE study were randomized to either atenolol-or losartan-based [...] 1350 8554 |
How Involvement in COVID-19-Related Work Changed Nurses' Job Demands, Job Resources, and Their Associations with Burnout: Evidence from China 1Abstract
China adopted a “Zero-COVID” policy for nearly three years, making Chinese healthcare workers constantly involved in COVID-19-related work. However, little is known about how involvement in COVID-19-related work shaped Chinese nurses’ burnout. This study explores how nurses’ job demands and job resources are associated with their burnout by considering high and low frequent involvements in COVID-19-related work in China. This study employed a cross-sessional design. Guided by Job Demands-Resources (JDR) model, we d [...] 1287 8553 |
Piperine: A Savor Inducer and a Cancer ReducerAbstract
Spices have been used for many decades, and although new and improved culinary spices have been developed, black pepper (Piper nigrum) continues to retain its distinguished title as the “King of spices” due to its particular pungent taste. An alkaloid called piperine is the main component in black pepper that, besides generating the well-known taste, imparts well-documented immunomodulatory, anti-inflammatory, antimicrobial, antioxidant, and even anti-cancer properties; these properties have led to rigorous researc [...] 1088 8551 |
TOP