Table of Content

Open Access Original Research

Risk and Protective Factors for Poorer Overall Health, Increased Psychological Distress, and Suicidal Ideation Due to SARS-CoV-2 outbreak in the General Japanese Population

Received: 28 December 2020;  Published: 12 March 2021;  doi: 10.21926/obm.icm.2101008

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is expected to have harmed the mental health of numerous people worldwide. Therefore, the present study was aimed to explore the effects of the SARS-CoV-2 outbreak on the overall health of the general Japanese population, with a particular focus on identifying the factors associated with a requirement for mental health treatment. Japanese residents aged 18 years and above were surveyed online, and among the 1,500 obtained responses included for a [...]

1756 8375

Open Access Editorial

Welcoming the “Metaverse” in Integrative and Complementary Medicine: Introductory Overview

Received: 17 October 2023;  Published: 25 October 2023;  doi: 10.21926/obm.icm.2304046

Abstract

The digital transformation of healthcare is accelerating. At the forefront of this revolution is the development of the "metaverse." This multidimensional digital universe, where virtual and physical realities converge, is reshaping the potential of integrative and complementary medicine. In this special edition journal series, we explore how metaverse technologies such as virtual reality, augmented reality, avatars, digital twins, blockchain smart contracts, and more, are poised to revolutionize holistic healthcar [...]

1654 8375

Open Access Original Research

N2O Emission Pattern in A Legume-Based Agroecosystem

Received: 26 January 2023;  Published: 26 April 2023;  doi: 10.21926/aeer.2302029

Abstract

Legumes provide several ecological services to agroecosystems, but there is a lack of references on services related to N flows for a wide range of legume crops. N2O emissions were measured in two field experiments using a two-year legume-cereal crop sequence. In the first year (2014 and 2016), different legume crops were grown (lupin, pea, fava bean, common bean, soybean, chickpea) and compared to fertilized cereals (barley and sorghum). Once the seeds were harvested and the residues incorporated in the soil, unfe [...]

1633 8374

Open Access Original Research

Heavy Metal Concentration and Health Risk Assessment of Selected Fruits Sold in Jos Metropolis

Received: 27 February 2021;  Published: 12 May 2021;  doi: 10.21926/acr.2102013

Abstract

The present study investigated the level of heavy metals in selected fruits sold commonly in Jos, Nigeria. The fresh fruits (Avocado pear, Black currant, Egg Plant, Golden melon, and Soursop) were purchased from five major markets (Terminus, Farin Gada, Building materials, Bukuru, and Fobur) in Jos. Each fruit sample was collected in triplicate and analyzed using standard procedures. The concentration of heavy metals (Fe, Cu, As, Cd, Zn, Pb, Mn, and Cr) was determined using Graphite Furnace Atomic Absorption Spectr [...]

1451 8371

Open Access Original Research

The Induction of Histone H3K4 Methylation on the SI Gene Correlates with SI mRNA Levels in Enterocyte-Like Caco-2 Cells

Received: 18 December 2017;  Published: 30 October 2018;  doi: 10.21926/obm.genet.1804046

Abstract

Background: Histone modifications, including acetylation and H3 lysine 4 (K4) methylation, are thought to be associated with transcriptional activation during differentiation. Methods: mRNA and histone modifications around the sucrase-isomaltase (SI) gene in Caco-2 cells (a small intestine cell line) during differentiation were determined by qRT-PCR and chromatin immunoprecipitation, respectively. Results: Mono-, di-, and tri-methylation of histone H3K4 on the SI gene correlated with the induction of SI gene expres [...]

1735 8365

Open Access Review

The Autotaxin - Lysophosphatidic Acid Axis as a Novel Therapeutic Target for Liver Fibrosis

Received: 27 March 2019;  Published: 21 June 2019;  doi: 10.21926/obm.hg.1902024

Abstract

Chronic liver diseases affects millions of people worldwide each year. Upon chronic liver injury, a wound healing process ensues, leading to the accumulation of extracellular matrix (ECM) proteins. If the injury persists, this leads to liver fibrosis with excessive scarring of the liver and loss of liver function. Lysophosphatidic acid (LPA), a signaling molecule has shown to be involved in various biological processes, including wound healing process. Elevated plasma levels of LPA and its catalyst autotaxin (ATX), [...]

1504 8363

Open Access Review

Functional Prognosis of Spinal Cord Injury Due to Spinal Tuberculosis

Received: 03 October 2024;  Published: 18 March 2025;  doi: 10.21926/obm.neurobiol.2501279

Abstract

Spinal tuberculosis (TB), an extrapulmonary manifestation of TB, primarily involves one or multiple vertebrae, with a high prevalence at the thoracolumbar region, which can compromise spinal cord integrity and result in severe sequelae such as paraplegia, bladder and bowel dysfunction, and mobility limitation. This study aimed to review medical, surgical, and rehabilitation management, clinical outcomes, and prognostic factors of spinal TB with spinal cord injury (SCI). Research was conducted utilizing databases su [...]

1225 8356

Open Access Research Article

Single Cell Metabolic Landscape of Pituitary Neuroendocrine Tumor Subgroups and Lineages

Received: 04 September 2022;  Published: 20 February 2023;  doi: 10.21926/obm.neurobiol.2301157

Abstract

Pituitary neuroendocrine tumors (PitNETs) are common intracranial tumors comprising numerous subtypes whose metabolic profiles have yet to be fully examined. The present in silico study analyzed single-cell expression profiles from 2311 PitNET cells from various lineages and subtypes to elucidate differences in metabolic activities. Gonadotroph tumors exhibited high activities with histidine metabolism, whose activity is low in lactotroph tumors. Somatotroph tumors enriched for sulfur and tyrosine metabolism, while [...]

1459 8355

Open Access Editorial

Acknowledgement to Reviewers of Journal of Energy and Power Technology in 2021

Received: 05 January 2022;  Published: 06 January 2022;  doi: 10.21926/jept.2201001

Abstract

The editors of Journal of Energy and Power Technology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a cer [...]

1280 8345

Open Access Review

The Cost-Effectiveness of Mindfulness-Based Interventions for Medical Students: A Scoping Review

Received: 16 August 2024;  Published: 23 January 2025;  doi: 10.21926/obm.icm.2501007

Abstract

This scoping review aims to understand the available research and the quality of evidence about the cost-effectiveness of mindfulness-based interventions when applied to the medical student context. There is considerable literature pertaining to the application of mindfulness-based interventions in this context. However, the links between cost and effectiveness need to be established to ensure the relative integrity of these therapeutic systems. The participants included in the study were medical students (undergra [...]

1517 8344

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