Table of Content

Open Access Case Report

Living with Spondylolisthesis with (Relative) Equanimity

Received: 23 April 2018;  Published: 02 July 2018;  doi: 10.21926/obm.icm.1803013

Abstract

Objectives: Living with any chronic pain condition is a challenge that can be met when one reduces reactivity to the sensory and evaluative aspects of it. The aim of this case study is to show how a clinical psychologist with expertise in chronic illness applied Buddhist principles to her own experience. Methods: When one realizes that suffering is the combination of pain plus resistance then one can learn how to accept rather than exacerbate it. Applying the Four Noble Truths from Buddhist psychology to understand [...]

1880 9720

Open Access Research Article

Breathing-Based Meditation for Improving COPD Burden: A Mixed Single-Case and Qualitative Approach

Received: 21 June 2023;  Published: 19 December 2023;  doi: 10.21926/obm.icm.2304059

Abstract

Chronic obstructive pulmonary disease (COPD) impacts the physiological and psycho-emotional aspects of life. COPD-related secondary sequelae also synergistically interact with each other. For example, dyspnea affects the severity of breath, body functions, and the mind (e.g., anxiety, panic, fear). Such negative psycho-emotional states can further negatively impact the breath and the body (e.g., increased dyspnea). Given the breadth of the impact of COPD on multiple facets of health and well-being, it is essential [...]

1352 9716

Open Access Research Article

Family History, Genetic, and Other Cause-Related Beliefs among Breast Cancer Survivors

Received: 27 February 2019;  Published: 26 July 2019;  doi: 10.21926/obm.genet.1903087

Abstract

Patients’ lay theories about the cause of their cancer may influence patient behavior and adjustment, they have also been found to differ substantially from scientific evidence of cancer risk factors. This report describes beliefs about genetic causes of breast cancer, among 522 recently diagnosed breast cancer survivors participating in an observational study. Patients were asked to respond to an open-ended question about the cause of their cancer. Causes mentioned included family history, genetics, lifestyl [...]

1750 9711

Open Access Review

Non-Coding RNAs in Cutaneous Melanoma Development, Progression and Dissemination

Received: 13 March 2018;  Published: 15 May 2018;  doi: 10.21926/obm.genet.1802020

Abstract

Melanoma is a highly aggressive skin cancer with high incidence worldwide. There is growing evidence that aberrantly expressed non-coding RNAs (ncRNAs) play a role in the development, progression and dissemination of melanoma tumor cells. Among the many types of ncRNAs described in this review, the functions of micro- and long non-coding RNAs are described and related to the six hallmarks of cancer. Recently, ncRNAs discovered in body fluids have become known as one of the most promising groups of oncological bioma [...]

1915 9708

Open Access Original Research

Moldavian Dragonhead Extract: A Natural Collagen-Booster to Target Skin Aging

Received: 09 December 2024;  Published: 03 April 2025;  doi: 10.21926/obm.geriatr.2502305

Abstract

The complex process of skin aging results in noticeable changes, including decreased collagen content, reduced elasticity, and decreased hydration. Interventions to preserve or restore collagen, a key structural protein, may help counteract these signs. The concept of "beauty from within” through nutritional supplements is of growing interest, particularly the use of plant-based alternatives to animal-derived or synthetic collagen. This study investigated the anti-aging potential of an extract from Moldavian dragon [...]

956 9706

Open Access Research Article

Correlation of CT and MR Perfusion and Permeability Parameters for Intracranial Tumors

Received: 07 October 2018;  Published: 13 January 2019;  doi: 10.21926/obm.neurobiol.1901019

Abstract

Background: Perfusion imaging, mainly MR perfusion (MRP), is performed frequently for brain tumor imaging. CT perfusion (CTP) is less studied as a method for characterizing brain tumors. The purpose of this study was to demonstrate the usefulness of CTP perfusion parameters in evaluating brain tumors and to compare it with MRP measures in the same patient population. Methods: Patients underwent CTP and MRP imaging prospectively. Images were processed with vendor-provided and vendor-neutral software. Four regions of [...]

1772 9705

Open Access Original Research

Quantification and Comparative Analysis of Environmental Factors to Large-Scale Solar Plant’s Energy Performance via Regression and Linear Correlation Models

Received: 15 September 2024;  Published: 02 January 2025;  doi: 10.21926/jept.2501001

Abstract

Performance degradation, including system deterioration, corrosion, and energy loss in solar PV systems, can be caused by environmental conditions such as high humidity, frequent rainfall, and temperature swings in tropical nations. Over the years, photovoltaic energy has been successfully developed to have low production costs and high efficiency. It has been the main reason that solar energy is one of the fastest-growing renewable energies in the world, with a generation of 821 TWh of electricity since 2021, repr [...]

1102 9702

Open Access Original Research

Formulation-Properties of Novel Ibuprofen-Loaded Soy Protein Wound Dressings

Received: 31 July 2019;  Published: 11 October 2019;  doi: 10.21926/rpm.1904004

Abstract

Background:Wound management is an important field in medical care, as annually, millions of wounds require treatment worldwide. Soy protein is highly biocompatible, easily processed, and a relatively cheap natural polymer, which can be used for wound dressing applications. Methods:In this study, solvent cast soy protein films, plasticized by glycerol and cross-linked by glyoxal, were thermally treated and their mechanical properties were evaluated as a function of various processing parameters. Samples were then lo [...]

2052 9701

Open Access Research Article

Transmitted Donor Immunology Not Infection: Common Persistence of Donor Hepatitis C Antibody Production in Aviremic Lung Transplant Recipients

Received: 16 September 2020;  Published: 13 January 2021;  doi: 10.21926/obm.transplant.2101134

Abstract

Since 2018 The American Society of Transplant has recommended that Hepatitis C Virus seropositive positive, non-viremic donors (HCVAb+/NAT-) be considered non-infectious and safe for transplantation. This report describes clinical outcomes and HCV serological and virological outcomes following lung transplantation (LTx) utilizing such donors. This retrospective cohort study describes seven HCVAb+/NAT- donors used for bilateral LTx. Donor information was sourced from the national organ donation service and recipient [...]

1842 9697

Open Access Review

The Changed Transcriptome of Muscular Dystrophy and Inflammatory Myopathy: Contributions of Non-Coding RNAs to Muscle Damage and Recovery

Received: 28 February 2019;  Published: 16 May 2019;  doi: 10.21926/obm.genet.1902079

Abstract

In order to successfully recover from damage, skeletal muscle tissue requires proper activation of a tightly orchestrated repair program. Non-coding RNAs actively participate in this complex process of demolition and rebuilding. In this review, the contribution of dysregulated non-coding RNA expression to disease-associated pathological changes is explored in hereditary muscular dystrophies and idiopathic inflammatory myopathies. Disturbances in spatiotemporal expression of non-coding RNAs appear to be key factors [...]

2051 9696

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