by Sara Schatz  and Melvin Gonzalez Rivera

Received: 15 March 2019;  Published: 13 August 2019;  doi: 10.21926/obm.geriatr.1903069

Pragmatic competence includes the capacity to express illocutionary force and successfully achieve perlocutionary effects, in order to guarantee fully functional communication exchanges. Improved pragmatic competence in patients has been found in patients with Mild Cognitive Impairment (MCI) and early to moderate Alzheimer’s Disease (AD) in the domains of jokes, self-expression and empathy after extended, targeted intranasal insulin therapy. In this paper it is argued that extended intra-nasal insulin treatment can [...]

by Danielle Graham  , Takahiro Ito  , Ronald Busuttil  and Fady Kaldas

Received: 05 May 2019;  Published: 29 July 2019;  doi: 10.21926/obm.hg.1903029

Acute pancreatitis is a highly morbid condition widely recognized and well-defined in the general population. In this article, we summarize the current literature on acute pancreatitis in the setting of solid organ transplant axiom, including patients who are listed for or have undergone transplantation. The literature is summarized by organ transplant type, including cardiac, lung, pancreas, kidney, intestine, and liver. Our review suggests that providers should have a high index of suspicion for acute pancreatiti [...]

by Behzad Foroutan

Received: 14 January 2023;  Published: 31 May 2023;  doi: 10.21926/obm.icm.2302023

Aging is a stage of the natural life cycle. It is a set of natural and coordinated growth changes all organs and body systems undergo to burnout. It is impossible to determine the exact time of old age for two reasons. First, the aging process is different for humans due to individual, hereditary factors. Second, aging has a set of physiological, psychological and, social factors. This review aimed to gather appropriate clinical information and facts for clinicians when practicing heart medications in elderly patie [...]

by Walid AL-ACHKAR  , Manar As’sad  , Thomas Liehr  , Adnan Ikhtiar  and Abdulsamad Wafa

Received: 14 August 2018;  Published: 20 June 2019;  doi: 10.21926/obm.genet.1902081

Background: The aggressive T-cell acute lymphoblastic leukemia (T-ALL) is one of the frequently occurring malignancies of the thymocytes. T-ALL is observed in 15% and 25% of all new diagnosed ALL cases in children and adults, respectively. Notably, T-ALL has a 3-fold higher incidence in males than in females. In nearly half of T-ALL cases, structural and/or numerical chromosomal abnormalities are detected, which have an important prognostic significance. A well-known genetic subtype of B-ALL, high hyperdiploidy (He [...]

by Megan Schutt  and Harvey Seim

Received: 10 April 2020;  Published: 30 April 2020;  doi: 10.21926/jept.2002006

SODAR wind profiler measurements from a land-based site within 1000 m of the coastal ocean are compared with predicted wind profiles based on upwind conditions and a stability-based model. The thermally dynamic influence of the Gulf Stream near the site of measurement, Cape Hatteras, has been found to complicate wind speed estimation at height through its impacts on atmospheric stability and the resulting changes to wind shear. The COARE 3.0 algorithm was used to calculate a Monin-Obukhov Similarity Theory (MOST) s [...]

by Marcel Ruiz-Mejias  , Patricia Castano-Prat  , Tony Donegan  and Maria V. Sanchez-Vives

Received: 31 December 2019;  Published: 14 February 2020;  doi: 10.21926/obm.geriatr.2001105

Aging and Alzheimer’s disease (AD) have been reported to induce changes in the cerebral cortex circuits. The present review aims to study these alterations by reviewing emergent cortical activity with a focus on the rhythmic patterns. The rationale for this approach was two-fold: (i) emergent rhythmic activity integrates cellular and network properties of these underlying circuits; and (ii) alterations in rhythmic patterns reflect the functional impact of changes on the network induced by the pathophysiology of the [...]

by Clara L.e Silva  , Bárbara H.S. Miranda  , Maria L. Vilela  , Jair F. Rodrigues  , Thainá G. Cunha  , Jhonatan A. Dias  , Gabriela A. Soares  , Vinicius Freitas  , Rodrigo de Q. Vilaça  , Luana Wouk  and Diego Bagnis

Received: 07 March 2022;  Published: 04 July 2022;  doi: 10.21926/jept.2203023

The lifetime and stability of organic photovoltaics (OPVs) are the key factors that influence the technology used to scale up and commercialize OPVs. High-performing and reliable devices are used to fabricate the devices of choice. Materials and methods that can be used to prevent the degradation of organic materials, enabling better OPV applications, are being increasingly researched in recent years. Herein, we present the surface modification process of a commercial, flexible barrier film based on polyethylene te [...]

by Félix Neto  and Maria da Conceição Pinto

Received: 23 January 2022;  Published: 08 June 2022;  doi: 10.21926/obm.neurobiol.2202125

This study analyzed the degree of loneliness, as well as acculturation and adaptation factors related to it among African migrants. The study sample consisted of 759 migrants (48.5% females) from four ethnocultural groups (Angolans, Cape Verdeans, Guineans, and Mozambicans) living in Portugal. Participants’ mean age was 37 years, and the mean length of sojourn in this country was 21 years. Participants completed self-reported questionnaires to evaluate social contacts, language proficiency, ethnic identity, perceiv [...]

by Laurence Pougnet  , Gilles Nevez  and Solène Le Gal

Received: 17 December 2018;  Published: 22 May 2019;  doi: 10.21926/obm.genet.1902080

Pneumocystis pneumonia (PCP) is the most frequent AIDS-defining disease among HIV-infected individuals in developed countries, and also affects immunocompromised non-HIV patients. Experimental studies on rodent models carried out in the early eighties have shown that Pneumocystis spp. can be transmitted via the airborne route. Unfortunately, this mode of acquisition and transmission has long been overlooked by physicians because PCP in immunosuppressed patients was considered to result from reactivation of a latent [...]

by Jessie Poquérusse  and Bryan W. Luikart

Received: 10 April 2017;  Published: 24 April 2017;  doi: 10.21926/obm.neurobiol.1702004

Large-scale genetic sequencing studies have identified a wealth of genes in which mutations are associated with autism spectrum disorder (ASD). Understanding the biological function of these genes sheds light onto the neurodevelopmental basis of ASD. To this end, we defined functional categories representing brain development – (1) Cell Division and Survival, (2) Cell Migration and Differentiation, (3) Neuronal Morphological Elaboration, (4) Development and Regulation of Cellular Excitability, and (5) Synapse Forma [...]