by Arnaud Philippot  , Yannick Bleyenheuft  and Anne De Volder

Received: 21 June 2020;  Published: 07 January 2021;  doi: 10.21926/obm.icm.2101002

In a previous study conducted to assess the impact of physical exercise on the symptoms of depression and anxiety in preadolescents in the school environment, which included a subgroup of participants comprising eleven randomly selected teens (aged 9–11) and all enrolled in primary education, it was immediately observed that one participant referred to as Andy was being bullied and teased, and the teachers were completely unaware of this scenario. All the participants of the study were volunteers, and were subjecte [...]

by Tara T. Lineweaver  , Suneeta Kercood  , Elyse B. Morgan  , Shelby L. Rampone  , Colleen C. Frank  , Scott A. McLuckie  and Mack F. Reed

Received: 27 October 2019;  Published: 07 January 2020;  doi: 10.21926/obm.icm.2001002

Past research suggests that exercise is associated with improved working memory (WM) abilities, and that athletes have better executive functioning and WM skills than non-athletes. However, no studies to date have separated the effects of exercise from the effects of athletic participation when examining WM. This study had three primary goals: (1) to determine whether amateur college athletes have better auditory and visual WM than their non-athlete peers who exercise frequently and whether non-athlete frequent exe [...]

by Nicholas Lim  , Gregory Beilman  and Timothy Pruett

Received: 21 March 2018;  Published: 12 June 2018;  doi: 10.21926/obm.transplant.1802011

Portal hypertension often occurs transiently with injection of islet cells into the portal system during total pancreatectomy-islet autotransplantation (TPIAT). We describe a TPIAT patient with non-cirrhotic portal hypertension (NCPH) two years after surgery initially identified with esophageal varices on upper endoscopy. The underlying mechanism for the development of NCPH after TPIAT is unclear but infectious and immune-related pathways have been proposed. Management of NCPH is primarily treatment of complication [...]

by Maud Gits-Muselli  , Stéphane Bretagne  and Alexandre Alanio

Received: 04 December 2018;  Published: 17 January 2019;  doi: 10.21926/obm.genet.1901060

Pneumocystis jirovecii is an atypical fungus transmitted via the airborne route between humans. This fungus is exclusively associated with humans and almost each individual has encountered it at least once before reaching the age of two. P. jirovecii can be cleared and spontaneously resolutive in immunocompetent, whereas it can be responsible for severe Pneumocystis pneumonia (PCP) in immunocompromised patients. In the next decades, the putative increase of the population of immunocompromised patients is likely to [...]

by Antonella Ciaramella

Received: 01 January 2020;  Published: 17 March 2020;  doi: 10.21926/obm.icm.2001014

Over the last 30 years, several neuroimaging and neurophysiological experiments have lent support to the neuropsychology of consciousness, and several definitions have followed to describe it. The phenomenological perspective of consciousness facilitates the description of the individual’s awareness experience of internal states (e.g., perception, sensations, emotion, volition, or memories), thus helping us to better understand the relationship between the brain and mind. Although significant research has been aime [...]

by Gerhard Litscher

Received: 11 November 2020;  Published: 13 November 2020;  doi: 10.21926/obm.icm.2004043

The Nogier reflex or reflex auriculo-cardiac (RAC) or the dynamic pulse reaction is a physiological phenomenon that is not generally accepted in conventional medicine. Therefore, evidence-based research in this sub-area is important for auricular medicine as it provides appropriate scientific evidence for better acceptance. In this editorial, a RAC measurement based on a modified smartphone registration and analysis is presented. The contribution is intended to stimulate researchers to continue working in this inte [...]

by Joep Geraedts

Received: 08 April 2019;  Published: 14 August 2019;  doi: 10.21926/obm.genet.1903089

Mitochondrial diseases are among the most prevalent inborn errors of metabolism. The overwhelming majority of mitochondrial diseases (about 85%) result from mutations in nuclear genes involved in oxidative phosphorylation, while some (15%) are caused by mutations in mitochondrial DNA (MtDNA). The familial mtDNA mutations are exclusively inherited from the mother. There are four main methods available to prevent the transmission of mtDNA mutations: preimplantation genetic diagnosis (PGD) or prenatal diagnosis (PND) [...]

by Mônica Batista Leite  and Paulo Roberto Lopes Lima

Received: 07 March 2021;  Published: 28 July 2021;  doi: 10.21926/rpm.2103032

The production of concrete using recycled aggregates, obtained from the processing of construction and demolition waste, is extensively practiced worldwide. However, the effect of simultaneous adding fine recycled aggregate and the recycled coarse aggregate on the mechanical properties of concrete is still unfamiliar. This work aims to evaluate the influence of the water/cement ratio (WC Ratio), the fine recycled aggregate content (%FRA), the coarse recycled aggregate content (%CRA), as well as the interaction betw [...]

by Em V. Adams  , Marieke Van Puymbroeck  , Heather S. Torphy  , Brian C. Helsel  , Karen A. Kemper  , Cheryl Dye  and Arlene A. Schmid

Received: 03 October 2019;  Published: 03 January 2020;  doi: 10.21926/obm.geriatr.2001097

Falls have negative consequences for older adults, but falls can be reduced through interventions that target the reduction of fall risk factors. Cognitive behavioral education programs and therapeutic yoga are two interventions that have independently been used as a means to reduce the risk of falls. The purpose of this study was to determine if adding therapeutic yoga following an education intervention improved well known fall risk factors. Potential participants were recruited through a senior center for a 12-w [...]

by Ryan Sweeney  , Alvaro J La Rosa  , Nina Sheade  , Rachael C. Olson-Marszewski  , Ryan Bergren  and Edwin Meresh

Received: 12 January 2020;  Published: 01 April 2020;  doi: 10.21926/obm.neurobiol.2002054

Case studies have associated catatonia with withdrawal from benzodiazepines and clozapine, both of which have been shown to increase GABA activity. Long-term use of GABAergic medications could result in GABAA downregulation and sudden discontinuation of the GABAergic drug could lead to a GABA hypoactive state which could predispose the patient to catatonia. The anticonvulsant topiramate, is known to increase brain GABA activity. Prader-Willi syndrome (PWS) is a genetic imprinting disorder characterized by lack of e [...]