OBM Geriatrics

(ISSN 2638-1311)

OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.

Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.

Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.

Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.

Archiving: full-text archived in CLOCKSS.

Rapid publication: manuscripts are undertaken in 6 days from acceptance to publication (median values for papers published in this journal in the first half of 2019, 1-2 days of FREE language polishing time is also included in this period).

Free Publication in 2019

Open Access Editorial

Fragility Fractures in the Elderly Osteoporotic Patient and the Efficacy of Fracture Liaison Service Programs

Tarik Wasfie, Avery Jackson III, Cara Marie Brock, Stefanija Galovska, Jennifer Hille
Received: November 07, 2019; Published: November 13, 2019; doi:10.21926/obm.geriatr.1904085

Abstract: None.

Open Access Case Report

Qualitative Evaluation of Interdisciplinary Service Learning Experience to Assess and Manage Fall Risk in Community-Dwelling Older Adults

Susan Kane Patton, Jennifer Vincenzo, Holly B. Bennett, Michelle Gray, Leah Jean Henry, Alishia Ferguson, Ro Dibrezzo, Christopher S. Walter, Maryalice Kelly
Received: August 15, 2019; Published: October 29, 2019; doi:10.21926/obm.geriatr.1904084

Abstract: Aim: This case study reports on the planning and implementation of a fall risk assessment and prevention activity for older adults offered in multiple community settings by health professional faculty and students. Background: In the US, the percentage of adults 65 and older who fell was more than 2 [...]

Open Access Review

Ageing: The Role of Ageism

Sheri R. Levy, MaryBeth Apriceno
Received: June 20, 2019; Published: October 28, 2019; doi:10.21926/obm.geriatr.1904083

Abstract: Worldwide, people are living longer but not necessarily experiencing optimal health since healthy ageing stems from a combination of biological, psychological, and social factors. The growing interdisciplinary literature on ageism from education, medicine, psychology, and social work increasingly h [...]

Open Access Research Article

Using Health-Related Quality of Life (SF-36v2®) to Predict Falls in Community-Dwelling Older Adults

Elena Crooks, Kimberly Cleary
Received: September 14, 2019; Published: October 25, 2019; doi:10.21926/obm.geriatr.1904082

Abstract: Background: Falls are the leading cause of hospitalization and death among older adults; therefore, the ability to predict fall risk among older adults is critical. Several performance-based outcome measures exist to assess fall risk. Psychological factors are also associated with fall risk yet can [...]

Open Access Concept Paper

Admiral Nursing in Primary Care: Peri and Post-Diagnostic Support for Families Affected by Dementia within the UK Primary Care Network Model

Zena Aldridge, Karen Harrison Dening
Received: September 19, 2019; Published: October 18, 2019; doi:10.21926/obm.geriatr.1904081

Abstract: The UK population is ageing. In 2017 approximately 18% of the UK population were aged 65 years or over and projected to grow to almost 21% by 2027 according to the Office of National Statistics (ONS) (2018a). Increased age is the greatest risk factor for developing dementia (Van de Flier & Sche [...]

Open Access Original Research

Naming and Framing the Behavioural and Psychological Symptoms of Dementia (BPSD) Paradigm: Professional Stakeholder Perspectives

Emma Wolverson, Heather Birtles, Esme Moniz-Cook, Ian James, Dawn Brooker, Frances Duffy
Received: September 08, 2019; Published: October 11, 2019; doi:10.21926/obm.geriatr.1904080

Abstract: Background Behavioural and Psychological Symptoms of Dementia and Challenging Behaviour in dementia care are just two of a variety of terms for a complex paradigm that covers the most distressing and costly aspects of the condition. The terminology used to describe these aspects can influence what [...]

Open Access Perspective

Behavioral versus Biological Definitions of Dementia Symptoms: Recognizing that Worthwhile Interventions already Exist

Robert J. Brent
Received: July 31, 2019; Published: October 10, 2019; doi:10.21926/obm.geriatr.1904079

Abstract: Background: The 2018 Alzheimer’s Disease Facts and Figures special report includes two new guidelines for measuring dementia symptoms. The first requires that a biomarker (biological factor) be added to a doctor’s clinical judgment of the cause of symptoms when determining whether dementia is presen [...]

Open Access Research Article

GAPcare: The Geriatric Acute and Post-Acute Fall Prevention Intervention for Emergency Department Patients – A Qualitative Evaluation

Elizabeth M. Goldberg, Cameron J. Gettel, Kelsey Hayes, Renee R. Shield, Kate M. Guthrie
Received: August 21, 2019; Published: October 10, 2019; doi:10.21926/obm.geriatr.1904078

Abstract: Three million US emergency department (ED) visits occur for falls each year. The mortality of falls is increasing and only one fourth of older adults report their fall to their primary care provider, suggesting that valuable preventative opportunities are missed. A fall prevention intervention initi [...]

Open Access Review

Aging in A Changing World – the Impact of Social Contact and Physical Activity on Health-Related Quality among Older People from Austria – A Biological Perspective

Sylvia Kirchengast
Received: June 23, 2019; Published: October 08, 2019; doi:10.21926/obm.geriatr.1904077

Abstract: Background: All over the world we are confronted with an absolute and relative increase of the portion of elderly people. In order to develop strategies to keep old aged people healthy and as long as possible independent, analyses of factors influencing health related quality of life (HRQL) during o [...]

Open Access Concept Paper

The “PRIMING, TIMING, MIMING” Model of Individualized Behavioural Care Planning for Residents with Dementia

Lindy A. Kilik
Received: July 30, 2019; Published: September 29, 2019; doi:10.21926/obm.geriatr.1903076

Abstract: Background: The current paper introduces the “Priming/Timing/Miming” Model of Behavioural Care Planning with persons with Dementia. This simple heuristic provides a quick, easy and systematic way to select from the vast number of behavioural strategies offered in the BPSD literature and to organize [...]

Open Access Original Research

Sleep Symptoms Differentially Predict Cognition in Younger and Older-Onset Parkinson's Disease

Maria E. Pushpanathan, Andrea M. Loftus, Natalie Gasson, Meghan G. Thomas, Romola S. Bucks
Received: May 13, 2019; Published: September 23, 2019; doi:10.21926/obm.geriatr.1903075

Abstract: Abstract Background: Both disrupted sleep and cognitive impairment are frequent in Parkinson’s disease (PD), but the evidence for a relationship between self-reported sleep disturbance and cognitive symptoms has been equivocal. If sleep symptoms differentially predict cognition in different subtype [...]

Open Access Review

Management of Neuropsychiatric Symptoms of Dementia: A Comprehensive Review of the Current Literature

Laura Suarez, Reem M.A. Shafi, Maria I. Lapid
Received: May 14, 2019; Published: September 16, 2019; doi:10.21926/obm.geriatr.1903074

Abstract: Purpose of Review: Dementia is a progressive and debilitating condition that affects millions of patients in the United States with an enormous impact on healthcare costs, caregivers, and society. Patients with dementia often experience dementia-related neuropsychiatric disturbances, commonly known [...]

Open Access Review

Facilitation of Social Support through Negative Allosteric Modulation of α5-Associated GABAA Receptors: A Novel Mechanism for the Treatment of Depression, Agitation, and Aggression in the Elderly

Jeffrey M. Witkin, Lalit K. Golani, Rok Cerne, Md. Toufiqur Rahman, Guanguan Li, Michael M. Poe, James M. Cook, Jodi L. Smith
Received: May 05, 2019; Published: August 26, 2019; doi:10.21926/obm.geriatr.1903073

Abstract: Major depressive disorder is a highly-prevalent and debilitating disorder in the aged population. Recent and accumulating clinical evidence suggests a key role for social support in helping to mitigate depression. Preclinical data are reviewed that indicate that selective negative allosteric modul [...]

Open Access Original Research

Wisdom of the Elders: Narratives Enhancing Trainees’ Attitudes Towards Aging

James S. Powers, Destiny O. Birdsong, Kemberlee R. Bonnet, Neena R. Kapoor, Jamaria J. Southward, Ifeoma Nwankwo, David G. Schlundt
Received: April 25, 2019; Published: August 26, 2019; doi:10.21926/obm.geriatr.1903072

Abstract: Background: Narratives encompass written reflection experiences and hold the potential to display valuable insights into trainees’ thinking. We analyzed narratives from graduate students trained in aging themes, who then interviewed older hospitalized adults (senior partners) about their life exper [...]

Open Access Original Research

Atrial Fibrillation, Anticoagulation, and Major Bleeding Episodes in Geriatric Patients at the Risk of Falling

Lennaert Zwart, Tjeerd Germans, Suat Simsek, Jaap Ruiter, René Jansen
Received: May 22, 2019; Published: August 26, 2019; doi:10.21926/obm.geriatr.1903071

Abstract: Background: Geriatric patients are at risk for atrial fibrillation (AF), stroke, and the risk of anticoagulation (OAC) related bleeding is presumed to be higher. Detailed knowledge about the prevalence of AF and bleeding pattern in this population is scarce. This study sought to assess the prevalenc [...]

Open Access Review

Shedding Light on Manic Syndromes and Dementia

Gabriele Cipriani, Sabrina Danti, Cecilia Carlesi, Claudio Lucetti, Angelo Nuti, Mario Di Fiorino
Received: March 27, 2019; Published: August 16, 2019; doi:10.21926/obm.geriatr.1903070

Abstract: Background. Mania in older adults is associated with a high rate of medical and neurological disease. Objective. The goal of this review is to describe the phenomenon of manic episodes in patients suffering from dementia. Methods. Medline and Google Scholar searches were conducted for relevant artic [...]

Open Access Original Research

Intranasal Insulin in Alzheimer’s Disease: A Pragmatic Account

Sara Schatz, Melvin Gonzalez Rivera
Received: March 15, 2019; Published: August 13, 2019; doi:10.21926/obm.geriatr.1903069

Abstract: Pragmatic competence includes the capacity to express illocutionary force and successfully achieve perlocutionary effects, in order to guarantee fully functional communication exchanges. Improved pragmatic competence in patients has been found in patients with Mild Cognitive Impairment (MCI) and ear [...]

Open Access Review

The Value Given and Presupposed in Person-Centred Dementia Care

Stephen Ames
Received: April 08, 2019; Published: August 13, 2019; doi:10.21926/obm.geriatr.1903068

Abstract: Thirty years ago, Tom Kitwood proposed a change in the care of people with dementia, from ‘warehousing’ to ‘person-centred care’. The change had noticeable benefits for those with dementia. Kitwood set out his presuppositions for this change. For example, Kitwood understood personhood as the stand [...]

Open Access Original Research

Differential Effects of Social Network on Health in Later Life and the Moderating Role of Depression

Shira Peleg, Howard Litwin
Received: March 23, 2019; Published: August 12, 2019; doi:10.21926/obm.geriatr.1903067

Abstract: Background: We studied the differential effects of social network characteristics on limitations with activities (LWA) and quality of life (QOL) among older adults, and the moderating role of depression. Methods: Data from two consecutive waves of the Survey of Health, Aging and Retirement in Europe [...]

Open Access Case Report

Personalised Medicine for Dementia: Collaborative Research of Multimodal Non-pharmacological Treatment with the UK National Health Service (NHS)

Garuth Chalfont, Jane Simpson, Sarah Davies, David Morris, Ruth Wilde, Leigh Willoughby, Christine Milligan
Received: April 08, 2019; Published: August 07, 2019; doi:10.21926/obm.geriatr.1903066

Abstract: The dominant narrative around dementia argues that progression cannot be halted or reversed. However, evidence on multimodal non-pharmacological treatments formulated around a ‘personalised medicine’ approach challenges this view. This paper reviews the current evidence for dementia prevention utili [...]

Open Access Review

A Model for Understanding Hispanic/Latino Family Caregiving for Older Adults

Hsueh-Fen S. Kao, Maria A. Amaya
Received: May 19, 2019; Published: August 07, 2019; doi:10.21926/obm.geriatr.1903065

Abstract: Background: In 2016, Hispanic/Latino (H/L) Americans made up 8% of the older population (≥65) and 22.9% of the oldest population (≥85) in the United States. It is projected that the older H/L population will grow to 21% by 2060. Currently the older H/L population depends primarily on their families [...]

Open Access Review

Insights from Yeast on Oxidative Stress in Alzheimer’s Disease, Focusing on Ahp1p/Prx5

Ian Macreadie, Sudip Dhakal
Received: May 05, 2019; Published: July 17, 2019; doi:10.21926/obm.geriatr.1903064

Abstract: The yeast, Saccharomyces cerevisiae, the model eukaryote, has provided many insights into molecular and cellular biology, as well as insights into many human diseases. In this paper we present some insights on how yeast studies are contributing to knowledge about the role of oxidative damage to cel [...]

Open Access Review

Curing Alzheimer’s Disease: Myriad Causes and Myriad Cures Await

Mario D. Garrett
Received: June 12, 2019; Published: July 16, 2019; doi:10.21926/obm.geriatr.1903063

Abstract: Simplifying the cause of Alzheimer’s disease has lulled the public into believing that the search for a cure is within reach. The disease has captured the attention of researchers worldwide, catapulting the disease as the third most funded research interest (after cancer and HIV). But after a centur [...]

Open Access Review

Role of Artificial Intelligence (AI) Art in Care of Ageing Society: Focus on Dementia

Tracy Harwood, John Maltby, Elizabeta B. Mukaetova-Ladinska
Received: March 28, 2019; Published: July 15, 2019; doi:10.21926/obm.geriatr.1903062

Abstract: Background: Art enhances both physical and mental health wellbeing. The health benefits include reduction in blood pressure, heart rate, pain perception and briefer inpatient stays, as well as improvement of communication skills and self-esteem. In addition to these, people living with dementia bene [...]

Open Access Original Research

Estimating Potential Cost Containment through Provision of Unplanned Institutional Respite Services to Support Home-Based Care within Japan’s Long-Term Care Insurance System

Yoko Moriyama, Timothy Bolt, Marilyn Luptak, Nanako Tamiya
Received: February 19, 2019; Published: July 09, 2019; doi:10.21926/obm.geriatr.1903061

Abstract: Background: Many informal caregivers providing at-home care to older family members want to continue serving as the primary caregiver if they get sufficient support. A key service enabling continued at-home care is access to unplanned respite care facilities for temporary institutional care on shor [...]

OBM Geriatrics welcomes the following types of articles: original research, review, communication, opinion, case report, comment, conference report, technical note, book review, etc. There is no restriction on the length of the papers, color figures, supplementary file types. More details please see Instructions for Authors.

Register and Submit now.

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