Table of Content

Open Access Original Research

The Multigenerational Legacy of Diabetes and Illness Perception: Influence on Older Adult’s Stigma

Received: 03 February 2024;  Published: 29 May 2024;  doi: 10.21926/obm.geriatr.2402280

Abstract

There is not enough information regarding the impact of stigma associated with a. diagnosis of diabetes in aging older adults. Perceptions of diabetes are passed down generationally and may be influenced by mainstream societal perceptions at the time the perception is shaped. This is known as a multigenerational legacy of diabetes for those with whom the perceptions are shaped within families when a hereditarily predisposed condition occurs. In this study, participants over the age of (n = 88) 60 years old were adm [...]

1062 5268

Open Access Original Research

Oleuropein can Protect the Brain Against Deleterious Effects of Bile Duct Ligation in Male Mice

Received: 26 December 2023;  Published: 23 April 2024;  doi: 10.21926/obm.neurobiol.2402218

Abstract

Oleuropein (OP) is a phenolic compound in olives. OP possesses potent antioxidant activity and an extensive spectrum of other pharmacological properties, including antiviral, anti-inflammatory, and antimicrobial activities. This study investigated the effects of OP on neural injuries caused by bile duct ligation (BDL) in male mice. The mice were randomly allocated to three groups: sham, BDL, and BDL + OP. Neurobehavioral tests histological and biochemical evaluations were accomplished to assess cerebral damage. The [...]

1062 4889

Open Access Editorial

Response-Guided Treatment with an Ultrarapid Virological Response Creates the Future of Interferon-Free Treatment against Hepatitis C

Received: 22 January 2017;  Published: 03 February 2017;  doi: 10.21926/obm.hg.1701002

1061 4996

Open Access Original Research

The Intra-Institutional Waste Management in Montevideo Healthcare Centers

Received: 23 September 2024;  Published: 20 May 2025;  doi: 10.21926/aeer.2502023

Abstract

Healthcare Waste (HCW) management is a pressing challenge in Latin America, where insufficient regulatory enforcement, poor segregation practices, and the lack of accurate generation data hinder sustainable waste management. This study presents a methodological proposal for the internal management of HCWs in Healthcare Centers (HCCs) in Uruguay, based on Decree 586/009 and developed through a situational diagnosis conducted at the Hospital de Clínicas "Dr. Manuel Quintela." The diagnosis involved the qualitative an [...]

1060 6358

Open Access Original Research

In Silico Evaluation of Anti-SARS-CoV-2 Bioactive Compounds from Jatropha curcas

Received: 12 March 2025;  Published: 25 May 2025;  doi: 10.21926/obm.genet.2502295

Abstract

Jatropha curcas L., a medicinal shrub renowned for its diverse phytochemicals, has been traditionally used to treat various ailments, including ulcers, neoplasms, and dermatological conditions. Despite its pharmacological promise, its potential against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) remains unexplored. This study investigates the antiviral efficacy of J. curcas phytochemicals targeting the SARS-CoV-2 main protease (Mpro), a critical enzyme for viral replication, using advanced computat [...]

1060 5774

Open Access Research Article

Phytomodification Effects of Visceral Lymph Node Aging

Received: 09 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.geriatr.2304257

Abstract

Lymph nodes are prioritized in protecting and ensuring endoecological safety at different periods of life, especially in retirement age. It destabilizes the structure and function of the lymphatic system and organs when aging increases the risk of comorbid conditions. This is a sign of age-related pathology. Improving lymph node function is an essential task in integrating gerontology and lymphology. The solution to this problem is possible with the help of a phytotherapeutic agent, which involves the evaluation of [...]

1060 6010

Open Access Short Review

Normal and Aberrant Muscle Tissue Healing, Learning from Health and Disease

Received: 28 March 2023;  Published: 19 September 2023;  doi: 10.21926/obm.genet.2303192

Abstract

Human skeletal muscle exhibits remarkable plasticity, being responsive to chemical, mechanical, metabolic, and inflammatory stress. When the homeostatic disturbance is below a threshold of significant damage, the muscle responds by modifying metabolic activity, cell size/shape, and structure, thereby normalizing cellular function. If the disturbance causes significant damage, skeletal muscle, along with a precisely choreographed response from the immune system, can regenerate. Very few pathological conditions inhib [...]

1059 7398

Open Access Original Research

Some Value-Added Met-Ocean Products to the RAMMB’s TC Surface Analysis for Marine Meteorological Applications

Received: 31 August 2023;  Published: 20 December 2023;  doi: 10.21926/aeer.2304054

Abstract

In the realm of air-sea interaction and marine meteorology, during a tropical cyclone (TC) worldwide since 2006, the Regional and Mesoscale Meteorological Branch (RAMMB) has issued surface wind analysis. Based on this TC’s isotach (line of equal wind speed) analysis, in this paper, much more meteorological-oceanographic (met-ocean) products are developed and value-added to these isotachs. They are, for marine meteorology, overwater friction velocity, wind stress, atmospheric vorticity and the mean vertical velocity [...]

1056 6085

Open Access Concept Paper

Wave Age and Steepness Relation in Growing Wind Seas: A Case Study during Hurricane Matthew in 2016

Received: 12 March 2023;  Published: 20 June 2023;  doi: 10.21926/aeer.2302037

Abstract

For wind-wave interaction studies, from the literature, two criteria for the wind sea are used: one is the wave age and the other wave steepness. Analysis of pertinent datasets from a data buoy near the passage of Hurricane Matthew in 2016 indicates that CpU10 = -15 HsLp + 1.3. Here CpU10 is the wave age and HsLp is the wave steepness, where Cp is the phase speed of the peak wave, U10 is the wind speed at 10 m, Hs is the significant wave height, and Lp is the peak or dominant wave length. It is found that 87% of th [...]

1055 7338

Open Access Concept Paper

The Bio Steel Cycle Meets Indoor Farming - CCUS with the SusCiP Principle in Agriculture

Received: 06 September 2024;  Published: 15 January 2025;  doi: 10.21926/aeer.2501006

Abstract

The World climate is changing, with a great impact on global food production systems. Extreme weather events, floods, wildfires and draughts are phenomena of disrupted previously stable natural weather patterns, which are vital for crop production and animal husbandry alike. Most of the World’s food is produced in temperate climatic zones rich in arable land and those are affected by the increasing unpredictability of previously naturally occurring seasons and weather conditions. This work aims to provide a possibl [...]

1054 5651

Open Access Case Report

Lung Transplantation from A Donor with Previous SARS-CoV-2 Infection: 1-Year Outcomes

Received: 25 October 2022;  Published: 06 January 2023;  doi: 10.21926/obm.transplant.2301173

Abstract

Few reports have described successful lung transplantation from a donor with a history of SARS-CoV-2 infection, and outcomes beyond 3 to 6 months remain unknown. After weighing the urgency and life-saving benefits of lung transplantation against the risk of viral transmission, we successfully performed a bilateral lung transplant from a donor with confirmed SARS-CoV-2 infection with mild symptoms 2 months before donation. At 1 year after transplant, there is no evidence of donor-derived viral transmission, and allo [...]

1054 6168

Open Access Original Research

The Effects of Control Measures and Social Networks on Depression Among Older People During the SARS-CoV-2 Pandemic

Received: 26 June 2022;  Published: 26 December 2022;  doi: 10.21926/obm.geriatr.2204217

Abstract

This study examined the correlates of change in the depressed state among people aged 65 and older during the SARS-CoV-2 pandemic, particularly the effects of crucial pandemic-related variables. Data were drawn from the longitudinal Survey of Health, Ageing and Retirement in Europe (SHARE), including information obtained from two special pandemic-related telephone interviews (N = 18, 266). The analysis regressed depressed state soon after the outbreak (T1) and again a year later (T2), on four pandemic-related varia [...]

1052 7378

Open Access Original Research

Pentachlorophenol Effect on Auxin Production by Pseudomonas fluorescens GU059580 and Its Application in Wastewater Bioremediation

Received: 29 July 2022;  Published: 18 November 2022;  doi: 10.21926/rpm.2204024

Abstract

Bioaugmentation by Pseudomonas strains is widely used for the removal of pollutants in wastewater. In this study, we aimed to determine the removal of pentachlorophenol (PCP, 800 mg·L–1) in secondary wastewater by the bioaugmentation process. We determined the effects of using three surfactants, namely sodium dodecyl sulfate (SDS), cetyl-tri-methyl-ammonium bromide (CTAB), and Tween 80 for PCP removal. We determined the effect of the role of PCP surfactant for the biofilm and auxin production of the se [...]

1052 6610

Open Access Original Research

Preimplantation Genetic Testing: Personal Views Regarding the Invasiveness of Trophectoderm Biopsy and Risks on Embryos Development “An Operators Survey”

Received: 02 January 2024;  Published: 07 March 2024;  doi: 10.21926/obm.genet.2401222

Abstract

This study aims to assess the Trophectoderm (TE) biopsy practice in Jordan in terms of the following effectiveness parameters: timing of zona breaching, risk of inner cell mass herniation if zona breaching was done on day 3, timing of TE sampling, method of biopsy (pulling or flicking), number of laser pulses, assessment of embryo survival after biopsy, and degeneration rate. An online cross-sectional survey was conducted in November 2022. The collected data presented the perception of embryologists (>10 years e [...]

1050 10635

Open Access Case Report

Use of Homeopathy in Patients Suffering from Long COVID-19 (LONGCOVIHOM): A Case Series

Received: 04 May 2024;  Published: 06 August 2024;  doi: 10.21926/obm.icm.2403045

Abstract

In some patients, coronavirus (COVID-19) can cause symptoms that last weeks or even months after the infection has gone. Long COVID-19 was defined as a confirmed initial COVID-19 infection, the presence of signs and symptoms more than four weeks after initial infection, and the persistence or appearance of signs and symptoms that another condition cannot explain and did not exist before infection. This study aimed to describe the effect of adjunctive individualized homeopathic treatment delivered to Long COVID-19 p [...]

1048 48291

Open Access Research Article

In Silico Evaluation of Bioactive Compounds (Flavonoids, Rosmarinic Acid) from Five Plants (Rosemary, Oregano, Pink Savory, Lemon Balm, and Saffron) and Their Role in Cardiovascular Health and Hypertension

Received: 22 January 2025;  Published: 25 June 2025;  doi: 10.21926/obm.icm.2502027

Abstract

Cardiovascular diseases and hypertension represent significant global health challenges, driving the need for innovative therapeutic solutions. In this study, we employed advanced in silico methods to investigate the molecular properties of two bioactive compounds, Flavonoids and Rosmarinic Acid, extracted from five medicinal plants: Rosemary, Oregano, Pink Savory, Lemon Balm, and Saffron. The bioactive compounds were evaluated against key biological targets associated with hypertension and cardiovascular diseases, [...]

1048 8342

Open Access Research Article

Spark Plasma Sintering of Cu-Ti-Ni Ternary Alloy: Microstructural, Thermal and Electrical Properties

Received: 28 December 2023;  Published: 01 July 2024;  doi: 10.21926/rpm.2403016

Abstract

High strength and good conductivity are both critical parameters for copper-based alloys for electrical and other technological applications. This study is aimed to produce copper alloys and metal matrix composites (MMCs) with enhanced physical properties. Cu-Ti-Ni ternary alloys and MMCs samples were sintered at 600 to 700°C using spark plasma sintering (SPS), with a heating rate of 100°C/minutes, uniaxial pressure of 50 MPa, and a holding time of 10 minutes. Scanning electron microscopy (FE-SEM) was used to exami [...]

1046 6096

Open Access Review

Modified Organized Systems by Incorporation of Carbon Allotropes and Derivatives for Electron Shuttle, ET, FRET, MEF, and Quantum Biology Coupling

Received: 14 October 2023;  Published: 31 January 2024;  doi: 10.21926/rpm.2401003

Abstract

This communication was brief to show how high conjugated carbon-based structures and carbon allotropes could participate as electron shuttles, semiconductors, quantum emitters, and Optoelectronic processors within confined nanostructured organized systems. In particular, it was focused on nanoassemblies such as vesicles, micelles, and lipidic nanoparticles and incorporated insights from other types of nanomaterials that could afford to develop new organized systems. In these cases, the term organized system was use [...]

1045 6427

Open Access Review

Poly ε-Caprolactone Scaffolds: Advancements in Bone Regeneration and Grafting

Received: 20 October 2024;  Published: 02 April 2025;  doi: 10.21926/obm.transplant.2502245

Abstract

In orthopedics and oncology, benign and malignant bone lesions pose significant clinical challenges. Malignant tumors, like osteosarcomas and multiple myeloma, pose substantial health dangers and can spread common and mostly non-life-threatening benign lesions, including non-sizing fibromas and unicameral bone cysts. Treatment plans for bone lesions may involve radiation, chemotherapy, and surgical excision, depending on their type. Combining stem cell research, bioactive materials, and advanced scaffold design, cu [...]

1045 8555

Open Access Editorial

The Next Frontier in Photocatalytic Hydrogen Generation

Received: 24 October 2025;  Published: 03 November 2025;  doi: 10.21926/cr.2504008

1044 3136

Open Access Editorial

Acknowledgement to Reviewers of OBM Neurobiology in 2021

Received: 05 January 2022;  Published: 06 January 2022;  doi: 10.21926/obm.neurobiol.2201114

Abstract

The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition di [...]

1042 6793

Open Access Editorial

OBM Transplantation—A New Hub in the Network of Transplantation Science

Received: 07 April 2017;  Published: 11 April 2017;  doi: 10.21926/obm.transplant.1701001

1042 9518

Open Access Research Article

Anti-Violence Centers in Italy During the COVID-19 Emergency: Support Strategies for Women Victims of Violence

Received: 16 August 2022;  Published: 30 November 2022;  doi: 10.21926/obm.neurobiol.2204147

Abstract

The COVID-19 pandemic has negatively impacted anti-violence centers for women. This study aims to investigate how the COVID-19 pandemic restrictions affect: the assistance and protection functions of the anti-violence centers; the needs of women victims of violence; and the well-being of the professionals working with these women. Twenty-four Italian anti-violence centers were involved, and 29 women working there were interviewed. From the qualitative analysis of the texts, three main themes were identified regardi [...]

1041 7410

Open Access Case Report

Novel FLNC Gene Variant Associated with Hypertrophic Cardiomyopathy

Received: 13 August 2024;  Published: 12 October 2024;  doi: 10.21926/obm.genet.2404266

Abstract

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy, affecting approximately 1 in 500 people. It is the most common genetic cardiomyopathy inherited as a Mendelian trait in approximately 50% of patients, mainly due to pathogenic variants in genes encoding sarcomeric proteins. Mutations in the sarcomeric protein filamin C (FLNC) gene, with a cytogenetic localization on 7q32.1, have been linked to hypertrophic cardiomyopathy, as they have been determined to increase the risk of ventricular a [...]

1040 5796

Open Access Original Research

Evaluation of Add-On Individualized Homeopathic Medicines Products in the Treatment of Symptomatic COVID-19 Managed at Home: A Double Blind, Placebo-Controlled, Randomized, Exploratory Clinical Trial

Received: 23 March 2024;  Published: 31 July 2024;  doi: 10.21926/obm.icm.2403044

Abstract

Homeopathy has shown promise in fighting epidemics, leading to potential applications in the COVID-19 clinical cases. To assess the impact of add-on individualized homeopathic medicinal products (IHMP) on improving clinical outcomes and time to medical discharge in COVID-19 patients, a prospective, double-blind, randomized, placebo-controlled, parallel-group exploratory clinical trial was conducted in a São Paulo state municipality, Brazil, between February and July 2021. 82 (unvaccinated) patients with conf [...]

1040 9438

Open Access Interview

An Interview with Dr. Joep Geraedts

Received: 17 February 2022;  Published: 22 February 2022;  doi: 10.21926/obm.genet.2201148

1039 6844

Open Access Original Research

The Timing of Endoscopic Evaluation of Anti-TNFα Therapy Patients with Ulcerative Colitis

Received: 10 August 2020;  Published: 09 July 2021;  doi: 10.21926/obm.hg.2103058

Abstract

Anti-TNFα Therapy are used to induce remission and as maintenance therapy in refractory ulcerative colitis (UC) to achieve mucosal healing (MH). However, the time at which mucosal healing should be assessed is unclear. We retrospectively examined the optimal timing for colonoscopy and the criteria to determine the need for the continuation of treatment. We evaluated 44 UC patients that were treated with anti-TNFα Therapy and categorized them into the following groups according to the degree of MH within 12 months: [...]

1039 5551

Open Access Editorial

The Human Touch in Acupuncture: A Future with Artificial Intelligence?

Received: 05 January 2025;  Published: 07 January 2025;  doi: 10.21926/obm.icm.2501003

Abstract

Acupuncture, an ancient practice in traditional Chinese medicine, is founded on understanding of human physiology and the dynamics of energy flow (Qi). The emergence of artificial intelligence (AI) in modern medicine presents opportunities to integrate advanced technologies into acupuncture, enhancing diagnostic precision and empirical validation. AI tools can analyze complex datasets, model energy flow dynamics, and provide evidence-based insights, potentially bridging traditional methodologies with scientific par [...]

1039 7996

Open Access Original Research

Detection of Activated Pepsin in Bronchoalveolar Lavage and Acute Cellular Rejection in Lung Transplant Recipients

Received: 23 February 2024;  Published: 21 June 2024;  doi: 10.21926/obm.transplant.2402219

Abstract

Activated pepsin (pepA) in bronchoalveolar lavage (BAL) fluid may be a biomarker of gastric aspiration. We sought to i) evaluate the association of pepA in BAL fluid with acute cellular rejection (ACR) in a cohort of lung transplant recipients (LTRs), ii) assess the association between pepA and isolation of typical gastrointestinal microorganisms from BAL fluid, and iii) explore the accuracy of using pepA concentration as a biomarker of ACR. After IRB approval, we conducted a retrospective observational study analy [...]

1037 5721

Open Access Original Research

Tacrolimus Therapeutic Response, Pharmacokinetics and Adherence in Liver Transplant Recipients

Received: 20 August 2024;  Published: 13 December 2024;  doi: 10.21926/obm.transplant.2404228

Abstract

A high intra and interindividual pharmacokinetics variability characterize Tacrolimus. Data regarding factors influencing its pharmacokinetics and pharmacodynamics in liver transplantation are limited. This study aimed to assess tacrolimus therapeutic response, pharmacokinetics and adherence in liver transplant recipients. The study was conducted at the Clinical Pharmacology Department for 12 years, from January 2009 to March 2021. We included liver transplant patients treated with tacrolimus referred to our depart [...]

1037 9584

Open Access Review

The Relevance of Diet in Musculoskeletal Clinical Practice—A Narrative Review

Received: 16 May 2024;  Published: 27 September 2024;  doi: 10.21926/rpn.2403015

Abstract

Musculoskeletal (MSK) pain is a multifaceted problem, with many contributors. The assessment of these contributions by clinicians has evolved to include not only the musculoskeletal and nervous systems, but also psychosocial contributions. Nutrition, however, has not been considered as a potential contributor in the same way, despite a significant body of evidence showing that amending one’s diet may significantly reduce pain and inflammation. Historically, when the biomedical model was considered the gold standard [...]

1036 12549

Open Access Original Research

Construction and Evaluation of a Modular Anthropomorphic Phantom of the Skull with an Exchangeable Specimen Jar to Optimize the Radiological Examination of Temporal Bone Pathology

Received: 26 March 2024;  Published: 25 July 2024;  doi: 10.21926/rpm.2403018

Abstract

To develop a modular anthropomorphic phantom to evaluate the performance of radiological techniques for detecting pathologies in the temporal bone region. A phantom was constructed using a human skull, temporal bone specimen, and 3D-printed contour of a human skull. The human skull was embedded in tissue-equivalent plastic, with a cavity to hold the plastic jars containing the exchangeable freshly frozen human temporal bones. Subsequently, stepwise introduction and examination of different clinicopathological scena [...]

1035 5189

Open Access Original Research

Contribution of a Single Islet Transplant Program to Basic Researchers in North America, Europe, and Asia through Distributing Human Islets

Received: 23 February 2024;  Published: 23 April 2024;  doi: 10.21926/obm.transplant.2402212

Abstract

There has been a steady expansion in islet isolation and transplantation activity worldwide. In addition to preparing human islets for transplantation, we have been providing human islets to basic researchers. The aim of this study was to review the activity of distribution of human islets to basic researchers in North America, Europe, and Asia, and to investigate if there are any differences in utilization rate of islets among three continents. We reviewed our islet isolation batch files, donor records, and docume [...]

1033 7277

Open Access Case Report

Maternally Derived Complex Small Supernumerary Marker Chromosome 22 Associated with Cat-Eye Syndrome Like Features

Received: 14 October 2024;  Published: 27 January 2025;  doi: 10.21926/obm.genet.2501282

Abstract

Cat-eye syndrome (CES) is a rare genetic disease first reported in 1965. The estimated prevalence of CES is 1:50,000 to 1:150,000, and it is typically associated with an inverted duplicated small supernumerary marker chromosome (sSMC) derived from chromosome 22. The specific chromosomal band involved in CES causing partial tetrasomy is 22q11.21, where chromosomal rearrangements occur due to the presence of low-copy repeats (LCR22). The phenotype of CES is extremely diverse, ranging from normal to multiple abnormali [...]

1032 5518

Open Access Editorial

Islet Transplantation: How Much Have We Advanced and How to Keep Moving Forward?

Received: 11 December 2022;  Published: 19 December 2022;  doi: 10.21926/obm.transplant.2204171

1032 6945

Open Access Opinion

Prevention of Drug Resistant Epilepsy and Developmental Epileptic Encephalopathy: Preventative Vigabatrin Treatment in Tuberous Sclerosis Complex and the Case for Fenfluramine Treatment of Children with Newly Diagnosed Dravet Syndrome

Received: 15 February 2024;  Published: 08 May 2024;  doi: 10.21926/obm.genet.2402234

Abstract

Tuberous sclerosis complex (TSC) is caused by mutations of hamartin (TSC1) or tuberin (TSC2) resulting in disinhibition of the mTOR pathway of cellular proliferation and differentiation and severe neurocognitive impairment, intractable epilepsy and tumors. Epilepsy develops in ~90% folllowed by drug-resistant epilepsy (DRE). Recently, prevention of DRE and developmental encephalopathy was shown to be possible in TSC using early administration of vigabatrin. For the first time, medical treatment successfully prevent [...]

1031 6169

Open Access Original Research

Physico-Chemical Study of the Anti-Diabetic Drug of [BzN-EJJ-amide] for Treatment Type2 Diabetes Using CNT Sensor by Drug Delivery Method

Received: 22 February 2024;  Published: 19 June 2024;  doi: 10.21926/obm.genet.2402245

Abstract

The potential and selective inhibitors of protein tyrosine phosphatase 1B (PTP1B) are therapeutically useful in treating type 2 diabetes. N-Benzoyl-L-glutamyl-[4-phosphono(difluoromethyl)]-L-phenylalanine-[4-phosphono(difluoro-methyl)]-L-phenylalanineamide (BzN-EJJ-amide) (BGD) which is the ligand of 1LQF protein code extracted from protein data bank (PDB) is an inhibitor of PTP-1B that indicates selectivity over several protein tyrosine phosphatases. In this research, the interaction between the anti-diabetic drug [...]

1031 4808

Open Access Original Research

Assessment of a Person's Social Success Through the Characteristics of Interpersonal Relationships in A Virtual Environment

Received: 30 April 2023;  Published: 13 November 2023;  doi: 10.21926/obm.neurobiol.2304195

Abstract

The sudden spread of the COVID-19 pandemic has convincingly proved the role of social networks in human life activity as an actor of interpersonal relations. The need for isolation and the limitation of face-to-face communication between people has significantly transformed the system of interpersonal connections through an extensive increase in social contacts in the virtual environment and the growing importance of online social services. In the study, we addressed the problem of diagnosing the indicator of socia [...]

1031 6689

Open Access Review

Mycotoxins Exposure: Neuroinflammation, Cognitive Decline and Behavioral Alteration

Received: 13 June 2025;  Published: 21 October 2025;  doi: 10.21926/obm.neurobiol.2504305

Abstract

Evidence from recent studies has suggested a significant association between mycotoxin exposure and neuroinflammation, potentially contributing to the onset of neurocognitive disorders during key developmental stages of the brain. Various research highlights how exposure to these toxins is correlated with a decline in cognitive performance, reduced motor skills, and behavioral issues. Mycotoxins are also implicated in interfering with neuronal signaling pathways and the functioning of neurotransmitters, which may l [...]

1031 5810

Open Access Original Research

Application of the Extrapolation Method in Battery Diagnostics for Electric Vehicles

Received: 17 August 2022;  Published: 14 November 2022;  doi: 10.21926/rpm.2204023

Abstract

In a lithium-ion battery, the crossing of its charging–discharging curves represents an unambiguous current capacity. The reproduction of a complete charging–discharging cycle defines the maximum possible charge for a current battery state. When obtaining of the curves experimentally, one should consider the duration of polarization or depolarization. It is reported that the battery capacity depends considerably on the value of the battery’s internal resistance as this value defines the location of the actual charg [...]

1031 6629

Open Access Original Research

Impact of Feeding Time and Duration on Body Mass and Composition in Young, Exercising Mice

Received: 21 December 2022;  Published: 22 August 2023;  doi: 10.21926/rpn.2303014

Abstract

Time-restricted feeding (TRF) has increased in popularity among various groups, including fitness enthusiasts. The ideal timing of TRF in relation to daily exercise is unknown. Most fitness enthusiasts consume meals immediately or soon after exercise to improve body composition (e.g., lean mass). We compared two different TRF approaches, as well as an ad libitum control diet, with regards to body mass and body composition in C57BL/6 mice. Young, healthy, male mice exercised five days per week and were assigned to c [...]

1030 6488

Open Access Research Article

Relationship between the Severity of Chest CT Scan Lesions, Arterial Oxygenation and Inflammatory Markers in High – Altitude Patients with Covid-19

Received: 01 December 2022;  Published: 19 April 2023;  doi: 10.21926/obm.genet.2302180

Abstract

This study aims to determine the relationship between the severity of lung tomographic compromise with arterial oxygenation and inflammatory markers in patients with COVID-19, and to evaluate the relationship between the CTSS tomographic severity score and the mortality risk in a high-altitude population. A retrospective, longitudinal study reviewed medical records between January and July of 2021 at the Daniel Alcides Carrión Regional Teaching Clinical Surgical Hospital in Huancayo. Categorical variables were anal [...]

1029 7476

Open Access Case Report

Unraveling and Expanding the Genotypic Spectrum of Kabuki Syndrome with Identification of de Novo Protein-Truncating Mutations in the KMT2D Gene: Insights into the Role of Premature Stop Codons in the Etiology of the Disorder

Received: 16 January 2025;  Published: 21 May 2025;  doi: 10.21926/obm.genet.2502294

Abstract

Kabuki Syndrome (KS) is a rare, multisystem congenital disorder with five foremost clinical manifestations encompassing dysmorphic facial characteristics, postnatal growth constraint, craniofacial/skeletal anomalies, mild to moderate intellectual disability, and dermatoglyphic abnormalities. We analyzed two unrelated Iranian patients suspected of having KS using whole-exome sequencing. An in silico analysis was performed to evaluate the potential effects of the discovered variants on the structure and function of t [...]

1029 6001

Open Access Editorial

Acknowledgment to Reviewers of Recent Progress in Nutrition in 2022

Received: 05 January 2023;  Published: 05 January 2023;  doi: 10.21926/rpn.2301001

Abstract

The editors of Recent Progress in Nutrition would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of re [...]

1029 6079

Open Access Original Research

Attenuation of Blood Glucose by the Ketone Monoester (R)-3-betahydroxybutyrate Glyceride in Healthy Male Sprague Dawley Rats in Response to a Standard Oral Glucose Tolerance Test

Received: 31 January 2025;  Published: 25 July 2025;  doi: 10.21926/rpn.2503014

Abstract

Efficient glucose uptake by peripheral tissue is important for individuals who desire to maintain optimal wellbeing. Various methods to regulate postprandial blood glucose have been reported in the research literature, however, few have examined the effect of ketone esters on blood glucose levels. The present study evaluated blood glucose following the administration of an oral glucose tolerance test, with and without ketone esters delivered at two different dosages, in a sample of healthy Sprague-Dawley rats. We h [...]

1027 5474

Open Access Original Research

Effect of Convective Mixing Process on Storage of CO2 in Saline Aquifers with Layered Permeability

Received: 19 October 2020;  Published: 25 February 2021;  doi: 10.21926/acr.2101012

Abstract

Convective mixing of free-phase CO2 and brine in saline aquifers is an established technique to accelerate the CO2 dissolution process. Correct estimation of the convection onset time and rate of CO2 dissolution into brine are two crucial parameters regarding safety issues, as the timescale for dissolution corresponds to the same time over which the free-phase CO2 has a chance to leak out from the storage site. In real practice, underground formations are heterogeneous with a layered structure, but the convective m [...]

1026 7177

Open Access Original Research

Impact of Normalization Methods on Metagenomic Characterization of Amaranthus Cruenthus var. Pribina-Associated Microbiomes Under Cadmium Stress

Received: 17 January 2025;  Published: 15 July 2025;  doi: 10.21926/obm.genet.2503303

Abstract

The study of endophytic and rhizosphere microbiota offers considerable potential for applications in agriculture, biotechnology, and bioremediation, given the phytoremediation capacity of Amaranthus cruentus var. Pribina performed a detailed analysis of the root and rhizosphere microbial communities under cadmium (Cd) stress. Although metagenomics provides powerful tools for microbial community profiling, the reproducibility and interpretability of the results are strongly influenced by the data processing strategi [...]

1025 3784

Open Access Research Article

Grid-Connected Photovoltaic System for Generating Energy to Dairy Farm Activities

Received: 28 April 2024;  Published: 26 August 2024;  doi: 10.21926/jept.2403016

Abstract

Minas Gerais is the leading milk-producing state in Brazil, and many dairy activities are supplied with electricity by the cable aerial network of the electrical energy state company. Given that the Brazilian energy matrix relies primarily on hydroelectric power, studies on the potential of other renewable energy sources in the context of dairy farms are innovative. Additionally, frequent disturbances and interruptions have motivated the installation of solar energy systems on dairy farms. However, the scarcity of [...]

1025 5607

Open Access Original Research

Monitoring Survival Following Lung Transplantation with Inclusion of Unaccounted Risks

Received: 07 November 2022;  Published: 14 March 2023;  doi: 10.21926/obm.transplant.2301177

Abstract

Lung transplant (LTx) survival and quality of life have been steadily improving, partially from changes in candidate selection for transplantation. There are well-known high-risk factors that lead to poor LTx outcomes, which may be referred to as ‘accounted’ risks. However, there are also other ‘unaccounted’ risks that are not included in the existing model for expected LTx survival to help programs for resource allocation. We performed a retrospective cohort study of all LTx recipients over the age of 18 at UC San [...]

1025 6819

Open Access Editorial

A Healthy and Happy 2019

Received: 15 January 2019;  Published: 15 January 2019;  doi: 10.21926/obm.genet.1901059

Abstract

A healthy and happy 2019

1024 6609

TOP