Table of Content

Open Access Short Review

Maximal 4-Second Cycle Accelerations Attenuate Sarcopenia and Improve Cardiovascular Function in Older Adults

Received: 20 February 2025;  Published: 08 August 2025;  doi: 10.21926/obm.geriatr.2503320

Abstract

The shrinkage of muscles with age, beginning at 30 y and accelerating in old age, is due largely to atrophy of fast-twitch muscle fibers (FT) partly from disuse. It was our purpose to develop an exercise program that is effective and time efficient at stimulating FT, as well as slow-twitch fibers (ST), to offset their atrophy. FT are recruited during movements requiring very high force and/or high velocity. We developed a safe exercise cycle that allows a person to ‘accelerate’ with the maximal effort needed to rec [...]

984 4797

Open Access Review

The Independence Principle - A Neglected Feature of the Hodgkin Huxley Legacy

Received: 19 May 2024;  Published: 17 March 2025;  doi: 10.21926/obm.neurobiol.2501278

Abstract

The legacy of Hodgkin and Huxley rests on their squid giant axon studies, which were summarised in an empirical model of impressive predictive power that successfully quantified the permeability changes of excitable membranes and accurately reconstructed the action potential. Hodgkin and Huxley applied the independence principle to their experimental data in order to reveal potential mechanism(s) of trans-membrane ion movements. This was motivated by their lack of information on the manner in which ions crossed the [...]

952 4759

Open Access Original Research

The Screening Strategies Used to Establish Egyptian Women Entrepreneurs’ Attitudes towards Genetic Technology

Received: 12 March 2024;  Published: 12 June 2024;  doi: 10.21926/obm.genet.2402241

Abstract

In this quantitative study, the researcher examined the screening strategies used to establish Egyptian women entrepreneurs' attitudes toward genetic technology. Using a questionnaire, the researcher collected data from 318 Egyptian women entrepreneurs. From applying the path analysis through Analysis of Moment Structures (AMOS) version 26.0, this study’s findings demonstrate genomic knowledge’s positive effect on attitudes towards genetic technology (β = 0.176; p = 0.003). The path analysis shows that, on the one [...]

1010 4752

Open Access Review

Platelets as Regenerative Cells, Hundreds of Opportunities in Sight

Received: 21 May 2024;  Published: 13 August 2024;  doi: 10.21926/obm.transplant.2403223

Abstract

Platelets were the last to be discovered of the three formed blood elements. Several scientists have been interested in them, recognizing them as cells other than leukocytes and erythrocytes. Its job in hemostasis and thrombosis is currently known. Platelets contain growth factors and secrete cytokines, which have roles in inflammation and tissue regeneration processes. This is why platelet concentrates have been widely used in regenerative medicine, an emerging field that involves biomolecules, cells, and scaffold [...]

794 4743

Open Access Original Research

Investigating Interest in Cancer Predisposition Testing and Expanded Carrier Screening in Routine Gynecologic Care among Pregnancy Capable Individuals

Received: 28 May 2024;  Published: 25 March 2025;  doi: 10.21926/obm.genet.2501288

Abstract

The goal of this qualitative study was to explore pregnancy capable individuals’ perceptions of having cancer predisposition testing (CPT) and/or expanded carrier screening (ECS) during routine gynecologic care and how these perceptions differ across individuals. A thematic analysis was conducted based on qualitative data from 26 semi-structured interviews with women between 20 and 35 years of age at a single academic health center in the Mountain West of United States. The analysis indicated that participants’ int [...]

1187 4739

Open Access Editorial

Catalysis, Meet the Machine: From Models to Meaning

Received: 25 June 2025;  Published: 27 June 2025;  doi: 10.21926/cr.2502005

1035 4734

Open Access Original Research

Winter Cover Crops: Relationship between Photosynthetically Active Radiation Interception and Weed Number and Productivity

Received: 04 July 2024;  Published: 06 January 2025;  doi: 10.21926/aeer.2501004

Abstract

The aim of this work was to determine the photosynthetically active radiation interception (iPAR) during the cover crop (CC) growth cycle, the number and aerial dry matter (ADM) of weeds, and productivity in the following soybean and maize rotation crop. To do this, experiments with CC were performed in 2015-2016 using Hordeum vulgare L., Lolium multiflorum L., Avena sativa L., Bromus unioloides L., Vicia villosa L., Brassica campestris L., Raphanus sativus L., and Avena sativa/Vicia villosa. The iPAR at the vegeta [...]

844 4733

Open Access Review

Precision Medicine in Liver and Lung Transplantation: Integrating Immunology, Regenerative Therapies, and Computational Advances

Received: 25 May 2025;  Published: 09 September 2025;  doi: 10.21926/obm.transplant.2503257

Abstract

Liver and lung transplantation remain among the most intricate and resource-intensive arenas in modern medicine, challenged by organ scarcity, immunological complexities, and the persistent threat of rejection. According to recent WHO and UNOS reports, approximately 100,000 patients globally await liver transplants annually, with only 30-40% receiving transplants, resulting in waitlist mortality rates of 15-20%. Similarly, lung transplant demand exceeds supply by a factor of 4:1, with 5-year survival rates remainin [...]

1087 4726

Open Access Review

An Exploration of the Psycho-Social Factors that Impact the Mental Wellbeing of Unaccompanied Asylum-Seeking Children in UK: A Narrative Review

Received: 23 January 2025;  Published: 17 July 2025;  doi: 10.21926/obm.icm.2503031

Abstract

Unaccompanied asylum-seeking children (UASC) are amongst the most vulnerable populations worldwide, facing significant psycho-social and mental health challenges influenced by pre-migration, migration, and post-migration experiences. This narrative review examines the structural, legal, and practical factors affecting UASC, focusing on their lived experiences within the UK’s asylum system. Key areas explored include trauma caused by forced migration (pre-, during and post-migration), ethical dilemmas surrounding ag [...]

656 4710

Open Access Editorial

Acknowledgment to Reviewers of Recent Progress in Materials in 2022

Received: 04 January 2023;  Published: 04 January 2023;  doi: 10.21926/rpm.2301002

Abstract

The editors of Recent Progress in Materials would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of re [...]

845 4698

Open Access Original Research

A Novel Approach to Carbon Monoxide Removal Using Transition Metal-Doped Boron Nitride Nanosensors for Environmental Sustainability

Received: 12 November 2024;  Published: 02 April 2025;  doi: 10.21926/jept.2502006

Abstract

Adsorption of toxic gas of CO molecules by using transition metals of X (X = Ti, V, Cr, Co, Cu, Zn)-doped boron nitride nanocage (B5N10_NC) has been studied by computational chemistry. Based on NQR analysis, X-doped on B5N10_NC has shown the lowest fluctuation in electric potential and the highest negative atomic charge, including 0.2331 (copper), 0.3112 (cobalt), 0.5883 (chromium), 0.6853 (zinc), 0.6893 (vanadium) and 0.7499 coulomb (titanium), respectively, have presented the most tendency for being the electron [...]

1006 4695

Open Access Review

Scoping Review of Nutraceuticals Use in Mediterranean Diet

Received: 25 September 2023;  Published: 05 July 2024;  doi: 10.21926/obm.icm.2403039

Abstract

Mediterranean diet, considered key to varied diets, raises whether it is necessary to supplement it with compounds like nutraceuticals to obtain more benefits. A scoping review was conducted. Nine articles were selected that compared the effects of nutraceuticals on biochemical markers (such as total cholesterol (TC), low-density lipoprotein cholesterol (LDLc)), weight, and blood pressure in various studies to the results observed in groups only exposed to the Mediterranean diet. The aim was to assess the impact of [...]

873 4662

Open Access Interview

An Interview with Dr. Ines Testoni

Received: 25 June 2023;  Published: 27 June 2023;  doi: 10.21926/obm.geriatr.2302241

Abstract

InterviewAn Interview with Dr. Ines TestoniOBM Geriatrics Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: geriatrics@lidsen.comOBM Geriatrics 2023, volume 7, issue 2 doi:10.21926/obm.geriatr.2302241Received: June 25, 2023Accepted: June 26, 2023Published: June 27, 2023

921 4660

Open Access Original Research

Exploring Farmers’ Motivators and Barriers to Adopting Stress Management Behaviors

Received: 30 September 2024;  Published: 05 March 2025;  doi: 10.21926/obm.icm.2501013

Abstract

Farmers experience high levels of stress, with negative sequelae including physical illness, depression, anxiety, and suicide. Despite this, farmers are often reluctant to adopt stress management behaviors. This study collected survey data on motivators and barriers to stress management behavior change among farmers from 162 participants at a regional fruit and vegetable growers’ conference. Survey findings were analyzed using the Health Beliefs Model (HBM) as an organizing framework, calculating the frequency of s [...]

1002 4659

Open Access Original Research

Cultural Cells: A Circular Economy-Driven Blueprint for Creative Tourism and Regional Revitalization in Greece

Received: 11 June 2025;  Published: 11 November 2025;  doi: 10.21926/aeer.2504032

Abstract

This study proposes a novel creative tourism model integrating artistic creation with circular economy principles to foster regional revitalization in North Euboea, Greece. Employing a case study approach, it develops the concept of “Cultural Cells”—dedicated hubs for artists and art students specializing in painting and sculpture—designed to enhance tourism through immersive engagement. The methodology combines qualitative analysis of regional cultural and environmental assets with theoretical estimates of circula [...]

1141 4645

Open Access Original Research

The Symptomatic Expression in Chinese Patients with Suspected COVID-19 Omicron Variant Infection: A Clinical Case Registry Study

Received: 29 February 2024;  Published: 29 July 2024;  doi: 10.21926/obm.icm.2403043

Abstract

Little systematic research has been conducted into the symptomatic expression of COVID-19 infections in patients. It is known that symptomatic expression varies between patients, but the nature and extent of this variability is poorly understood. This paper elaborates on the symptoms reported by Chinese patients infected with COVID-19 during the Omicron wave, and compares this with available data from other countries. This was an observational clinical case registry study of Chinese patients with suspected Omicron [...]

853 4645

Open Access Short Communication

Good or Great: Which One Are You?

Received: 17 December 2023;  Published: 19 February 2024;  doi: 10.21926/obm.geriatr.2401269

Abstract

Clinicians caring for patients, especially those with chronic diseases or older adults, need to recognize the value of being able to transition away from aggressive care when appropriate and focus on a more palliative approach. Research has shown that patients want to have goals of care discussions and maintain autonomy at the end of life. These goals of care discussions can be challenging, and clinicians must prioritize and develop this skill in order to provide their patients with what they may need most. Being a [...]

1057 4643

Open Access Editorial

Acknowledgment to Reviewers of Recent Progress in Nutrition in 2023

Received: 04 January 2024;  Published: 05 January 2024;  doi: 10.21926/rpn.2401001

Abstract

The editors of Recent Progress in Nutrition would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up t [...]

936 4606

Open Access Short Report

X Ray-Induced Insulinoma Cell Line Rin-5F Has a Novel Mutation Site, C.A1459G (P.T487A), in Death Domain Associated Protein (DAXX) Gene

Received: 05 January 2024;  Published: 19 March 2024;  doi: 10.21926/obm.genet.2401223

Abstract

A popular toxicological and pharmacological research cell line is the insulin-secreting pancreatic cell line Rin-5F. The cell line originates from insulinomas induced by X-ray exposure. The author of this report looked at the mutation status of the DAXX gene in the Rin-5F cell line clone. The complete DNA and RNA were extracted from the cultivated cells as well. Double-stranded cDNA was then synthesized using the RNA template. Sequencing was done using a 3730xl DNA Analyzer. In the present study, c.A1459G (p.T487A) [...]

929 4567

Open Access Review

Exercise Training and Cardioprotection in Cardiovascular Disease: A Review of Mechanisms

Received: 27 November 2024;  Published: 05 August 2025;  doi: 10.21926/obm.icm.2503034

Abstract

Cardiovascular disease remains the leading cause of death worldwide, prompting extensive research into effective methods for treatment and prevention. Among these, exercise training and physical activity are widely recognized as the safest and most effective strategies for improving health. Specifically, exercise training has been explored for its role in cardioprotection, particularly in reducing damage caused by ischemia-reperfusion (I/R) injury and myocardial infarction (MI). Both high-intensity interval trainin [...]

858 4528

Open Access Original Research

Serum Shock Enhances Endogenous Melatonin Production and Mitochondrial Gene Regulation in U87-MG Glioblastoma Cells

Received: 14 March 2025;  Published: 07 July 2025;  doi: 10.21926/obm.genet.2503301

Abstract

Glioblastoma (GBM) is the most aggressive primary brain tumor, with a poor prognosis despite advancements in understanding its biology. Melatonin, a key regulator of metabolism and cellular homeostasis, is known for its neuroprotective and anti-cancer properties. While traditionally linked to pineal gland secretion, emerging evidence suggests that glioblastoma cells can produce melatonin within their mitochondria. This study investigates whether serum shock can influence endogenous melatonin production and mitochon [...]

1019 4520

Open Access Original Research

Modern UNOS Data Reveals Septuagenarians Have Inferior Heart Transplant Survival

Received: 10 November 2024;  Published: 11 June 2025;  doi: 10.21926/obm.transplant.2502252

Abstract

While heart transplantation is increasingly performed in the United States for elderly patients, survival outcomes have primarily been analyzed in single-center studies. The few existing long-term studies have indicated no difference in HTx outcomes between patients ≥70 years and 60-69 years age, but these studies only assessed to 5-years post-transplant and included data from the 1980-90s, introducing significant variance due to poorer outcomes in that era. We analyzed the UNOS database from 1987-2020, stratified [...]

940 4517

Open Access Editorial

Acknowledgment to Reviewers of OBM Integrative and Complementary Medicine in 2023

Received: 04 January 2024;  Published: 05 January 2024;  doi: 10.21926/obm.icm.2401005

Abstract

Food insecurity and insufficient access to affordable nutrition have been associated with increased risk for the development of multiple chronic medical conditions, including cardiovascular disease. In this narrative review, we explore the association between food insecurity and the development of chronic medical conditions that confer increased cardiometabolic risk, cardiovascular disease, and mortality. We also identify the various barriers leading to food insecurity and lack of food literacy, with an emphasis on [...]

948 4506

Open Access Case Report

Best Care for the Dying, Right Plan at the Right Time: A Case Report

Received: 31 January 2025;  Published: 28 May 2025;  doi: 10.21926/obm.geriatr.2502312

Abstract

The growing number of individuals with palliative care needs has led to an increased demand for specialized palliative care teams.. However, these teams often struggle to meet the demand, requiring all nurses to recognize and provide appropriate care during a patient’s last hours and days of life (LHDL). This case report aims to highlight the importance of identifying the LHDL and implementing individualized and adjusted care plans based on the 10/40 model of care. A descriptive-reflective case report following the [...]

1024 4500

Open Access Original Research

Germination-Induced Starch Influence on Structural Characteristics of Water-Soluble Extracts from Purple Pericarp Creole Corn

Received: 14 October 2024;  Published: 28 July 2025;  doi: 10.21926/rpn.2503015

Abstract

Germination is a viable, cost-effective, and environmentally friendly biotechnological process that enhances the industrial applications of cereals. This study evaluated the impact of germination (86 hours at 30°C) on soluble solids, proximate composition, and total phenolic compounds (TPC) in water-soluble extracts. It also included imaging analyses using scanning electron microscopy (SEM), X-ray diffraction (XRD), apparent amylose content, and starch pasting properties of purple pericarp Creole corn (PPCC) fr [...]

1038 4494

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