Table of Content

Open Access Original Research

Computer-Aided Study on Metal Complexes with Benzohydrazide Schiff Base as Potential Bacterial and Fungi Inhibitors

Received: 22 October 2024;  Published: 06 March 2025;  doi: 10.21926/rpse.2501002

Abstract

The biochemical properties of metal complexes containing benzo hydrazide Schiff base have been reported by numerous researchers worldwide in various ways. In this work, the evaluation of biochemical roles of the metal complexes with benzo hydrazide Schiff base activity as anti-gram positive and gram-negative bacteria, as well as antifungal agents, were observed. The use of various techniques, including the induced fit docking methodology, the density functional theory method, and pharmacokinetics investigations wit [...]

1244 4984

Open Access Editorial

Acknowledgment to Reviewers of OBM Neurobiology in 2022

Received: 05 January 2023;  Published: 05 January 2023;  doi: 10.21926/obm.neurobiol.2301149

Abstract

The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication, and they can download a certificate of reco [...]

848 4981

Open Access Original Research

Identification of Soybean Components that Prevent the Entry of Influenza Virus

Received: 31 August 2024;  Published: 01 April 2025;  doi: 10.21926/rpn.2502005

Abstract

We have previously demonstrated the anti-influenza virus activity of a soybean extract, indicating the presence of compounds that prevent viral entry into cells. In this study, we sought to identify the compounds in hydrothermal extracts of soybean that blocked viral entrance and analyzed their mechanisms of action. Hot aqueous extracts of roasted soybeans were separated by reverse-phase chromatography on an octadecylsilyl C18 column, and the antiviral activity of individual fractions was measured during the viral [...]

1028 4972

Open Access Original Research

Chest CT Scan Features of COVID-19 in a Hospitalized High-Altitude Population

Received: 30 November 2022;  Published: 12 April 2024;  doi: 10.21926/obm.genet.2402226

Abstract

There is a lack of knowledge regarding the type of lung compromise in high-altitude residents with COVID-19. This study aims to evaluate the lung compromise in chest CT scans of high-altitude dwellers hospitalized with COVID-19. Retrospective study that took place in "Daniel Alcides Carrión" Regional Hospital, located 3,250 meters above sea level in the city of Huancayo, Perú. 464 medical charts and chest CT images of hospitalized patients with confirmed COVID-19 from January to March 2021 were reviewed. The mean a [...]

1001 4968

Open Access Original Research

Characterization of Patients with Functional Syndromes and Paradoxical Response to Hypnotic Relaxation

Received: 30 July 2024;  Published: 27 April 2025;  doi: 10.21926/obm.icm.2502019

Abstract

Hypnotherapy is effective for treating functional symptoms; however, some studies describe a paradoxical response to hypnotic relaxation. We hypothesized that functional patients who: 1) are aware of a stressful antecedent event and 2) recognize that stress is causing or exacerbating their symptoms would have reduced symptom-severity with hypnotic relaxation, whereas patients who do not perceive a stressful antecedent and do not recognize stress as causing symptoms, would more commonly experience paradoxical respon [...]

772 4955

Open Access Correction

Correction: Tse et al. How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain. OBM Neurobiology 2023; 7: 183

Received: 11 March 2024;  Published: 12 March 2024;  doi: 10.21926/obm.neurobiol.2401213

Abstract

CorrectionCorrection: Tse et al. How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain. OBM Neurobiology 2023; 7: 183Mimi Mun Yee Tse 1, *, Shamay Sheung Mei Ng 2, Vivian Lou 3, Raymond SK Lo 4, Daphne Sze Ki Cheung 5, Paul H Lee 6, Shuk Kwan Tang 7, Siu Hang Leung 1, Percy Poo-See Tse 1* Correspondence: Mimi Mun Yee Tse; E-Mail: mmytse@hkmu.edu.hkAcademic Editors: Ines Testoni, Adriano Zamperini and Lorenza PalazzoSpecial Issue: How COVID-19 Changed Indi [...]

1064 4952

Open Access Review

Trends in Breast Cancer Epigenetics Research from 1993 to 2023: A Bibliometric Analysis

Received: 12 January 2025;  Published: 15 August 2025;  doi: 10.21926/obm.genet.2503307

Abstract

Breast cancer is a significant health problem. Epigenetic alterations that influence gene expression were implicated in breast cancer pathogenesis. Bibliometric analysis can be done to evaluate the existing literature and identify gaps and emerging trends. This bibliometric analysis aims to provide an overview of the current landscape of global breast cancer epigenetics research, identify existing networks of countries and authors’ keywords, and assess the association of a country’s socioeconomic indica [...]

811 4950

Open Access Review

Love in the Time of COVID: Psychiatric Outcomes Related to Oxytocin and the “Endocrine Organ”

Received: 09 February 2025;  Published: 09 May 2025;  doi: 10.21926/obm.neurobiol.2502287

Abstract

The COVID-19 pandemic was an eye-opener for many medical disciplines. It highlighted viral exploitation of physiological cellular processes, including endocytosis and cellular senescence. These pathways play an essential role in cancer, neurodegenerative disorders, and schizophrenia (SCZ). Oxytocin, commonly called the “love hormone,” is produced in the posterior hypothalamus and is crucial for various physiological processes, including social intelligence, sexual activity, and metabolism. Many viruses, [...]

907 4950

Open Access Editorial

In the Mirror of the Past, in the Light of the Future: The ISLA – A President Looks Back and Forward

Received: 15 June 2025;  Published: 18 June 2025;  doi: 10.21926/obm.icm.2502024

Abstract

This editorial for the 27th ISLA Congress in Beverungen in Germany reflects on the development, achievements, and challenges of the International Society for Medical Laser Applications (ISLA-transcontinental) from the perspective of its President for Science and Research, Univ.-Prof. DDr. Gerhard Litscher. It reviews the organization’s milestones and growth while outlining future strategies for innovation, research, and international collaboration in medical laser technologies. The full keynote presentation is avai [...]

1374 4946

Open Access Short Report

Integrating Palliative Medicine into Medical Education: Creating a More Compassionate Generation of Physicians

Received: 26 February 2024;  Published: 01 July 2024;  doi: 10.21926/obm.geriatr.2403281

Abstract

How should Palliative Medicine competencies be taught to medical students? In the United States and other countries, there is a consensus that teaching Palliative Medicine competencies to medical students is essential. Health agencies have also identified teaching Palliative Medicine competencies as crucial. According to Sanchez-Reilly and Ross, medical students reported that they feel better prepared to care for the elderly, patients with severe illness, and dying patients after completing formal training. The aut [...]

895 4924

Open Access Interview

An Interview with Professor Gerhard Litscher: “How High-Tech and Digitalization Are Revolutionizing the Future of Acupuncture”

Received: 11 September 2024;  Published: 11 September 2024;  doi: 10.21926/obm.icm.2403050

Abstract

In this interview Professor Gerhard Litscher discusses how new technologies like laser acupuncture and electroacupuncture, artificial intelligence (AI), and robotics are revolutionizing acupuncture by enhancing precision and personalization. He emphasizes the potential for digital tools to improve treatment outcomes and training while maintaining the human aspect of this holistic practice. Litscher highlights the importance of interdisciplinary collaboration and ongoing education to successfully integrate these inn [...]

648 4920

Open Access Editorial

Acknowledgement to Reviewers of OBM Geriatrics in 2022

Received: 04 January 2023;  Published: 04 January 2023;  doi: 10.21926/obm.geriatr.2301221

Abstract

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition dire [...]

869 4917

Open Access Original Research

Parenting Behavior and Early Childhood Mental Health: Cortisol Awakening Response as a Moderator of Child Internalizing and Externalizing

Received: 02 September 2024;  Published: 04 March 2025;  doi: 10.21926/obm.icm.2501011

Abstract

Certain observable parenting behaviors contribute to the risk of children developing internalizing and externalizing problems. Yet parenting behaviors do not affect all children uniformly and effects may depend on identifiable child characteristics. One factor is a child’s biological sensitivity to the caregiving environment, an indicator of which is a stress hormone, cortisol. This longitudinal study examines two dimensions of observable parenting behaviors, responsive and rejecting/harsh. These parenting behavior [...]

1370 4913

Open Access Original Research

A New Database on Constitutional Human Ring Chromosomes

Received: 20 April 2025;  Published: 26 June 2025;  doi: 10.21926/obm.genet.2502298

Abstract

Human ring chromosomes (RCs) constitute one of the rarest described inborn chromosomal rearrangements. At first, they seem to be just another subgroup of structural chromosomal aberrations like translocations, inversions, or insertions. However, RCs are more complex, as they almost always occur in conjunction with a mosaic karyotype constitution, resulting in mosaic monosomy of the affected chromosome. Most likely due to the latter effect, a genotype-phenotype correlation is still not available. To proceed with sol [...]

766 4904

Open Access Original Research

The Multiple, Embodied Positive Effects of a Community-Based Aerial Sling Class: Improved Body Schema, Fitness, Mental Health, and Diet

Received: 06 April 2025;  Published: 17 July 2025;  doi: 10.21926/obm.icm.2503032

Abstract

Contrary to the dominant ultra-cognitive approach in public health whereby only thought processes are supposed to link to action (e.g., physical activity) and health, in this research an embodied (body-mind unison) philosophy was examined by showcasing the importance of holistic and performative movement experiences to health and well-being. Specifically, the purpose of this study was to comprehensively examine the interrelated, multiple, and embodied benefits of a community-based aerial sling class (“Flow”) on bod [...]

971 4890

Open Access Original Research

Management of Atrial Fibrillation after Kidney Transplant: Do We Need a New Metric?

Received: 06 December 2024;  Published: 27 February 2025;  doi: 10.21926/obm.transplant.2501238

Abstract

To evaluate the bleeding risk associated with anticoagulation (AC) in kidney transplant patients with post-operative atrial fibrillation (AF). We conducted a retrospective analysis of all adult kidney transplant recipients performed from October 2012 to February 2019 at our institution, the University of North Carolina at Chapel Hill, which accounted for 428 transplants. Variables assessed included AF occurrence, AC use, bleeding complications, stroke and bleeding risk stratification in AF (determined using CHA2DS2 [...]

741 4861

Open Access Concept Paper

Applied Pragmatic Functional Contextualism: A New Epistemological and Theoretical Framework for Applied Mental Health Research

Received: 22 January 2024;  Published: 10 July 2024;  doi: 10.21926/obm.icm.2403041

Abstract

This paper argues that psychology, as a discipline, requires research to be situated in the context of a content-based theory. We identify several problems and pitfalls with requiring a content-based theory for applied mental health research, a priori. Nonetheless, we also articulate a rationale for why theory matters and that a new sort of theoretical framework is required for applied mental health research. We address this need by articulating a new theoretical framework called Applied Pragmatic Functional Contex [...]

839 4852

Open Access Editorial

Acknowledgment to Reviewers of Journal of Energy and Power Technology in 2023

Received: 04 January 2024;  Published: 05 January 2024;  doi: 10.21926/jept.2401001

Abstract

The editors of Journal of Energy and Power Technology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can [...]

995 4851

Open Access Editorial

Mysteries in Acupuncture - Future Research?

Received: 19 July 2023;  Published: 21 July 2023;  doi: 10.21926/obm.icm.2303031

Abstract

The editorial lists 10 important topics that need to be considered more closely in the future in acupuncture research.

919 4831

Open Access Editorial

Acknowledgment to Reviewers of OBM Integrative and Complementary Medicine in 2022

Received: 05 January 2023;  Published: 05 January 2023;  doi: 10.21926/obm.icm.2301003

Abstract

The editors of OBM Integrative and Complementary Medicine would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a cer [...]

854 4830

Open Access Case Report

Papillon-Lefèvre Syndrome and Vitamin D Deficiency: An Intriguing Clinical Observation

Received: 06 April 2025;  Published: 24 June 2025;  doi: 10.21926/obm.genet.2502297

Abstract

We report the case of a 3-year-old girl from a consanguineous marriage, initially diagnosed with vitamin D deficiency–associated periodontitis following early tooth mobility. Despite supplementation, her condition worsened with the onset of palmoplantar hyperkeratosis. Further investigations revealed the diagnosis of Papillon-Lefèvre Syndrome (PLS), a rare genetic disorder causing severe periodontitis and palmoplantar keratosis. The patient was managed with vitamin D supplementation, dental extractions, and a remov [...]

733 4824

Open Access Original Research

Hassles during the First Year of Medical School: Can a Student Wellness Program Make a Difference?

Received: 14 March 2024;  Published: 27 September 2024;  doi: 10.21926/obm.icm.2403057

Abstract

Acute stress during medical school affects medical student well-being. The objective of the current study was to examine the influence of a holistic, school-sponsored student wellness program (SWP) on acute stress during the first year of medical school. First-year medical students attending two osteopathic medical schools participated, one school with a holistic student wellness program (SWP group) and one without an organized student wellness program (Control group). The SWP was founded on osteopathic philosophy [...]

820 4817

Open Access Perspective

Atimiaphobia: A Phenomenological Account of the Fear of Losing Honor or Being Labeled Shameless due to the Sexual Values Assigned to Femininity

Received: 30 May 2025;  Published: 10 September 2025;  doi: 10.21926/obm.icm.2503037

Abstract

Honor and shame function as moral currencies in many collectivistic cultures, shaping individual behavior, gender roles, and psychosocial well-being. This paper introduces Atimiaphobia—a newly proposed specific phobia defined as the intense and persistent fear of losing honor (particularly for men) or being labeled as shameless (particularly for women). Rooted in patriarchal, collectivist, and honor-based cultures, atimiaphobia manifests through intrusive thoughts, hypervigilance, emotional turmoil, and compu [...]

920 4815

Open Access Original Research

Molecular Cytogenetic Characterization of Rare but Repeatedly Observed Translocations

Received: 15 April 2024;  Published: 11 June 2024;  doi: 10.21926/obm.genet.2402240

Abstract

Balanced chromosomal rearrangements, including translocations, contribute to infertility, repeated abortions, and/or genetically imbalanced offspring in corresponding carriers. A translocation is usually considered a unique, de novo, or familial event. Besides, some translocations have also been shown to develop multiple times with slightly different or even identical breakpoints; for others, founder effects have been suggested. Here, two known recurrent translocations [t(11;22)(q23.3;q11.21) and der(X)t(X; Y)(p22. [...]

1024 4812

Open Access Review

Physio-Chemical and Molecular Characterization of Salinity Stress in Wheat: Mitigation Approaches and Future Perspectives

Received: 09 July 2025;  Published: 10 November 2025;  doi: 10.21926/obm.genet.2504316

Abstract

Wheat constitutes the backbone of global food supplies, and its production is directly linked to the food and nutritional security of the mounting population. Wheat is vulnerable to abiotic stresses like heat, salinity, and drought. These abiotic stresses tend to reduce the food security of the increasing population by reducing wheat production and nutritional quality. Among abiotic stresses, salinity stress (SS) has emerged as the most prevailing stress in modern high-input wheat farming systems, as it severely ha [...]

1227 4806

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